| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K A Strait, R Kuczensk. Dopamine autoreceptor regulation of the kinetic state of striatal tyrosine hydroxylase. Molecular pharmacology. vol 29. issue 6. 1986-07-18. PMID:2872588. |
the observations that dopamine and apomorphine can block forskolin activation of tyrosine hydroxylase, that this blockade can in turn be prevented by preincubation with haloperidol or chlorpromazine, and that the amount of dopamine required for blockade of forskolin activation in synaptosomes has no effect on tyrosine hydroxylase when added to the enzyme assay constitute the first clear evidence of a presynaptic dopamine receptor (autoreceptor). |
1986-07-18 |
2023-08-11 |
Not clear |
| K A Strait, R Kuczensk. Dopamine autoreceptor regulation of the kinetic state of striatal tyrosine hydroxylase. Molecular pharmacology. vol 29. issue 6. 1986-07-18. PMID:2872588. |
failure of dopamine to block dibutyryl cyclic amp activation of tyrosine hydroxylase suggests that, if forskolin and dibutyryl cyclic amp activate tyrosine hydroxylase through identical changes in phosphorylation state, then autoreceptor regulation of tyrosine hydroxylase must occur through a decrease in cyclic amp levels. |
1986-07-18 |
2023-08-11 |
Not clear |
| V W Yong, T L Perry, W J Godolphin, K A Jones, R M Clavier, M Ito, J G Foulk. Chronic organic manganese administration in the rat does not damage dopaminergic nigrostriatal neurons. Neurotoxicology. vol 7. issue 1. 1986-07-14. PMID:2872639. |
this was assessed by measurements of tyrosine hydroxylase activity and contents of dopamine and its metabolites in the striatum, and by histological examination of the substantia nigra. |
1986-07-14 |
2023-08-11 |
mouse |
| R B Simerly, R A Gorski, L W Swanso. Neurotransmitter specificity of cells and fibers in the medial preoptic nucleus: an immunohistochemical study in the rat. The Journal of comparative neurology. vol 246. issue 3. 1986-06-20. PMID:2422228. |
for this, we used an indirect immunohistochemical method with antisera to serotonin (5ht), dopamine beta-hydroxylase (dbh), tyrosine hydroxylase (th), neuropeptide y (npy), cholecystokinin (cck), vasoactive intestinal polypeptide (vip), substance p (sp), neurotensin (nt), corticotropin-releasing factor (crf), luteotropin-releasing hormone (lrh), somatostatin (ss), thyrotropin-releasing hormone (trh), oxytocin (oxy), vasopressin (vas), adrenocorticotropic hormone (1-24; acth), alpha-melanocyte-stimulating hormone (alpha-msh), leucine-enkephalin (l-enk), and calcitonin gene-related peptide (cgrp). |
1986-06-20 |
2023-08-11 |
rat |
| M F Notter, M Gupta, D M Gas. Neuronal properties of monkey adrenal medulla in vitro. Cell and tissue research. vol 244. issue 1. 1986-06-06. PMID:2870811. |
cells exhibited intense histofluorescence for catecholamines even after three weeks in vitro in the presence of ngf and positive staining for tyrosine hydroxylase and dopamine beta hydroxylase could be detected by immunocytochemistry. |
1986-06-06 |
2023-08-11 |
monkey |
| D H Park, G Teitelman, M J Evinger, J I Woo, D A Ruggiero, V R Albert, E E Baetge, V M Pickel, D J Reis, T H Jo. Phenylethanolamine N-methyltransferase-containing neurons in rat retina: immunohistochemistry, immunochemistry, and molecular biology. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 6. issue 4. 1986-06-06. PMID:2871139. |
the results show that there are two types of pnmt-containing cells: those containing pnmt exclusively and those containing pnmt with two other catecholamine-synthesizing enzymes, tyrosine hydroxylase (th) and aromatic l-amino acid decarboxylase (aadc), but not dopamine beta-hydroxylase (dbh). |
1986-06-06 |
2023-08-11 |
rat |
| R A Altschuler, D W Hoffman, R J Wenthol. Neurotransmitters of the cochlea and cochlear nucleus: immunocytochemical evidence. American journal of otolaryngology. vol 7. issue 2. 1986-05-21. PMID:2870655. |
immunoreactivities to enkephalins, dynorphins, calcitonin gene-related peptide, and tyrosine hydroxylase (a marker for dopamine) are also found in lateral efferents. |
1986-05-21 |
2023-08-11 |
Not clear |
| R A Mayer, A S Walters, R E Heikkil. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration to C57-black mice leads to parallel decrements in neostriatal dopamine content and tyrosine hydroxylase activity. European journal of pharmacology. vol 120. issue 3. 1986-04-22. PMID:2868908. |
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) administration to c57-black mice leads to parallel decrements in neostriatal dopamine content and tyrosine hydroxylase activity. |
1986-04-22 |
2023-08-11 |
mouse |
| R A Mayer, A S Walters, R E Heikkil. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration to C57-black mice leads to parallel decrements in neostriatal dopamine content and tyrosine hydroxylase activity. European journal of pharmacology. vol 120. issue 3. 1986-04-22. PMID:2868908. |
the administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) to c57-black mice (4 doses of 20 mg/kg, at 2 h intervals) led to a large decrement in the neostriatal content of dopamine (92%) and a parallel decrease in tyrosine hydroxylase activity (91%). |
1986-04-22 |
2023-08-11 |
mouse |
| B Meister, T Hökfelt, W W Vale, P E Sawchenko, L Swanson, M Goldstei. Coexistence of tyrosine hydroxylase and growth hormone-releasing factor in a subpopulation of tubero-infundibular neurons of the rat. Neuroendocrinology. vol 42. issue 3. 1986-04-03. PMID:2869425. |
the distribution of growth hormone-releasing factor (grf) and tyrosine hydroxylase (th), a marker for dopamine neurons in this region, was analyzed in the mediobasal hypothalamus with indirect immunofluorescence histochemistry and an elution-restaining procedure. |
1986-04-03 |
2023-08-11 |
rat |
| N T Glanville, G H Anderso. Hypothalamic catecholamine metabolism in diabetic rats: the effect of insulin deficiency and meal ingestion. Journal of neurochemistry. vol 46. issue 3. 1986-04-02. PMID:2869102. |
also normal were the rates of 3,4-dihydroxyphenylalanine accumulation following aromatic amino acid decarboxylase inhibition, norepinephrine and 3,4-dihydroxyphenylethylamine (dopamine) clearance after tyrosine hydroxylase inhibition, and intraneuronal amine accumulation following monoamine oxidase inhibition. |
1986-04-02 |
2023-08-11 |
rat |
| H Nissbrandt, E Pileblad, A Carlsso. Evidence for dopamine release and metabolism beyond the control of nerve impulses and dopamine receptors in rat substantia nigra. The Journal of pharmacy and pharmacology. vol 37. issue 12. 1986-03-20. PMID:2868096. |
in rat substantia nigra a biphasic disappearance curve of dopamine (da) was seen after tyrosine hydroxylase inhibition by alpha-methyl-p-tyrosine (alpha-mt): the initial phase had a fast turnover and a half life of 0.5 h and the later phase had an extremely slow turnover. |
1986-03-20 |
2023-08-11 |
rat |
| M Ekker, T L Sourke. Differential effects of thioridazine, clozapine and metoclopramide on the induction of adrenomedullary enzymes by apomorphine. Neuropharmacology. vol 24. issue 11. 1986-02-19. PMID:2867484. |
the induction of two adrenomedullary enzymes, ornithine decarboxylase and tyrosine hydroxylase, by apomorphine was studied in rats receiving dopamine antagonists known to by specific in their site of action. |
1986-02-19 |
2023-08-11 |
rat |
| H Baker, A F Sved, L W Tucker, S M Alden, D J Rei. Strain differences in pituitary prolactin content: relationship to number of hypothalamic dopamine neurons. Brain research. vol 358. issue 1-2. 1986-02-18. PMID:2866817. |
balb/cj mice have more tuberoinfundibular dopamine neurons, and thus greater tyrosine hydroxylase activity, than cba/j mice. |
1986-02-18 |
2023-08-11 |
mouse |
| K Andersson, P Eneroth, K Fuxe, F Mascagni, L F Agnat. Effects of chronic exposure to cigarette smoke on amine levels and turnover in various hypothalamic catecholamine nerve terminal systems and on the secretion of pituitary hormones in the male rat. Neuroendocrinology. vol 41. issue 6. 1986-02-13. PMID:3001559. |
there was also an increase in amine turnover (tyrosine hydroxylase inhibition by alpha-methyl-dl-p-tyrosine methylester; alpha mt) in the dopamine (da) systems of the medial and lateral palisade zones and in the periventricular noradrenaline (na) hypothalamic systems. |
1986-02-13 |
2023-08-11 |
rat |
| K T Demarest, K E Moore, G D Riegl. Acute restraint stress decreases tuberoinfundibular dopaminergic neuronal activity: evidence for a differential response in male versus female rats. Neuroendocrinology. vol 41. issue 6. 1986-02-13. PMID:4080091. |
tida neuronal activity was estimated by measuring the rate of dopamine (da) synthesis (dopa accumulation after the administration of a decarboxylase inhibitor, nsd 1015) and the rate of da turnover (decline of da after administration of a tyrosine hydroxylase inhibitor; alpha-methyltyrosine) in the median eminence. |
1986-02-13 |
2023-08-11 |
rat |
| T H Jo. Genes for neurotransmitter synthesis, storage and release. Progress in clinical and biological research. vol 192. 1986-02-07. PMID:2867555. |
we found that the catecholamine biosynthetic enzymes, tyrosine hydroxylase, dopamine b-hydroxylase and phenylethanolamine n-methyltransferase share similar protein domains in their primary structures, and therefore are coded for by a single gene or a family of genes. |
1986-02-07 |
2023-08-11 |
Not clear |
| L J Valenta, A N Elias, H Eisenber. ACTH stimulation of adrenal epinephrine and norepinephrine release. Hormone research. vol 23. issue 1. 1986-02-07. PMID:3000912. |
it is postulated that acth stimulated ne and e secretion by augmenting blood flow through the adrenals and by induction of tyrosine hydroxylase and dopamine beta-hydroxylase, although a direct effect of acth on ne and e secretion cannot be excluded. |
1986-02-07 |
2023-08-11 |
Not clear |
| M Bräutigam, B Kittner, G Laschinsk. Effects of apomorphine enantiomers and of lisuride on 3,4-dihydroxyphenylalanine production in striatal synaptosomes. Molecular pharmacology. vol 28. issue 6. 1986-01-29. PMID:3935908. |
as s(+)-apomorphine but not r(-)-apomorphine is considered to be a dopamine antagonist, these results support the assumption that the block of synaptosomal dopa production by both apomorphine enantiomers is due to a direct inhibition of tyrosine hydroxylase. |
1986-01-29 |
2023-08-11 |
Not clear |
| M Bräutigam, B Kittner, G Laschinsk. Effects of apomorphine enantiomers and of lisuride on 3,4-dihydroxyphenylalanine production in striatal synaptosomes. Molecular pharmacology. vol 28. issue 6. 1986-01-29. PMID:3935908. |
these results demonstrate that inhibition of synaptosomal dopa production by at least some dopamine agonists may be explained by direct inhibitory effects on tyrosine hydroxylase. |
1986-01-29 |
2023-08-11 |
Not clear |