| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Mugnaini, W H Oertel, F F Wouterloo. Immunocytochemical localization of GABA neurons and dopamine neurons in the rat main and accessory olfactory bulbs. Neuroscience letters. vol 47. issue 3. 1984-10-15. PMID:6147797. |
immunocytochemical localization of gaba neurons and dopamine neurons in the rat olfactory bulb was obtained with sheep antiserum to glutamate decarboxylase (gad) and rabbit antiserum to tyrosine hydroxylase (th). |
1984-10-15 |
2023-08-12 |
rat |
| P M Iuvon. Regulation of retinal dopamine biosynthesis and tyrosine hydroxylase activity by light. Federation proceedings. vol 43. issue 12. 1984-09-28. PMID:6147273. |
regulation of retinal dopamine biosynthesis and tyrosine hydroxylase activity by light. |
1984-09-28 |
2023-08-12 |
human |
| J C Davi. Relationship between phenolamines and catecholamines during rat brain embryonic development in vivo and in vitro. Journal of neurochemistry. vol 43. issue 3. 1984-09-13. PMID:6146658. |
the parallel developmental study of the activities of dopamine beta-hydroxylase, 3,4-dihydroxyphenylalanine decarboxylase, tyrosine hydroxylase, and monoamine oxidase shows that phenolamines are present in significant amounts in the hypothalamus until tyrosine hydroxylase and monoamine oxidase become catalytically active. |
1984-09-13 |
2023-08-12 |
rat |
| M E Morgan, B K Yamamoto, C R Free. Unilateral activation of caudate tyrosine hydroxylase during voluntary circling behavior. Journal of neurochemistry. vol 43. issue 3. 1984-09-13. PMID:6146659. |
we trained rats to circle for a sucrose water reward and found that this behavior is associated with a unilateral increase in the activity of caudate tyrosine hydroxylase, the rate-limiting enzyme for dopamine synthesis. |
1984-09-13 |
2023-08-12 |
rat |
| A F Sved, H A Baker, D J Rei. Dopamine synthesis in inbred mouse strains which differ in numbers of dopamine neurons. Brain research. vol 303. issue 2. 1984-08-30. PMID:6744023. |
balb/cj and cba/j mice have been shown to have different numbers of dopamine (da) neurons in the central nervous system, with balb/cj mice having 20-50% more da neurons in each dopaminergic cell group which is reflected in a difference in tyrosine hydroxylase activity in these cell groups. |
1984-08-30 |
2023-08-12 |
mouse |
| M J Zigmond, E M Stricke. Parkinson's disease: studies with an animal model. Life sciences. vol 35. issue 1. 1984-08-14. PMID:6146085. |
it appears that the loss of dopaminergic neurons is accompanied by an exponential increase in the ratio of tyrosine hydroxylase activity to dopamine content. |
1984-08-14 |
2023-08-12 |
rat |
| P T Ozand, R L Hawkins, R M Collins, W D Reed, P J Baab, M L Oster-Granit. Neurochemical changes in murine trisomy 16: delay in cholinergic and catecholaminergic systems. Journal of neurochemistry. vol 43. issue 2. 1984-08-08. PMID:6145755. |
the rate limiting enzymes of catecholaminergic neurons, tyrosine hydroxylase and dopamine beta-hydroxylase, and the concentration of catecholamines in the brains of ts16 animals were lower. |
1984-08-08 |
2023-08-12 |
mouse |
| W G Kuhr, A G Ewing, W L Caudill, R M Wightma. Monitoring the stimulated release of dopamine with in vivo voltammetry. I: Characterization of the response observed in the caudate nucleus of the rat. Journal of neurochemistry. vol 43. issue 2. 1984-08-08. PMID:6736965. |
(5) inhibition of tyrosine hydroxylase, and thus dopamine synthesis, decreases the observed release while inhibition of monoamine oxidase, and thus formation of dopamine metabolites, does not. |
1984-08-08 |
2023-08-12 |
rat |
| M Goldstei. Regulatory mechanisms of dopamine biosynthesis at the tyrosine hydroxylase step. Annals of the New York Academy of Sciences. vol 430. 1984-08-03. PMID:6146282. |
regulatory mechanisms of dopamine biosynthesis at the tyrosine hydroxylase step. |
1984-08-03 |
2023-08-12 |
Not clear |
| H Baker, T Kawano, V Albert, T H Joh, D J Reis, F L Margoli. Olfactory bulb dopamine neurons survive deafferentation-induced loss of tyrosine hydroxylase. Neuroscience. vol 11. issue 3. 1984-06-20. PMID:6144081. |
olfactory bulb dopamine neurons survive deafferentation-induced loss of tyrosine hydroxylase. |
1984-06-20 |
2023-08-12 |
Not clear |
| H Baker, T Kawano, V Albert, T H Joh, D J Reis, F L Margoli. Olfactory bulb dopamine neurons survive deafferentation-induced loss of tyrosine hydroxylase. Neuroscience. vol 11. issue 3. 1984-06-20. PMID:6144081. |
peripheral deafferentation of the rodent olfactory bulb results in loss of dopamine content, tyrosine hydroxylase activity and immunocytochemical staining for tyrosine hydroxylase in juxtaglomerular dopamine neurons. |
1984-06-20 |
2023-08-12 |
Not clear |
| H Baker, T Kawano, V Albert, T H Joh, D J Reis, F L Margoli. Olfactory bulb dopamine neurons survive deafferentation-induced loss of tyrosine hydroxylase. Neuroscience. vol 11. issue 3. 1984-06-20. PMID:6144081. |
reinnervation of the bulb by afferent neurons results in the return of all parameters to control levels suggesting that the dopamine neurons did not degenerate but that the expression of tyrosine hydroxylase enzyme was transneuronally regulated in a static population of juxtaglomerular cells. |
1984-06-20 |
2023-08-12 |
Not clear |
| H Baker, T Kawano, V Albert, T H Joh, D J Reis, F L Margoli. Olfactory bulb dopamine neurons survive deafferentation-induced loss of tyrosine hydroxylase. Neuroscience. vol 11. issue 3. 1984-06-20. PMID:6144081. |
the dopa decarboxylase activity measurements and immunocytochemistry argue for the continued presence, in the lesioned olfactory bulb, of a population of tyrosine hydroxylase deficient dopamine neurons. |
1984-06-20 |
2023-08-12 |
Not clear |
| G A Smythe, J E Bradsha. Different acute effects of the tyrosine hydroxylase inhibitors alpha-methyl-p-tyrosine and 3-iodo-L-tyrosine on hypothalamic noradrenaline activity and adrenocorticotrophin release in the rat. Australian journal of biological sciences. vol 36. issue 5-6. 1984-06-20. PMID:6144300. |
computerized gas chromatography-mass spectrometry techniques using selected ion monitoring and deuterated internal standards were used to assay simultaneously the medial basal hypothalamic concentrations of dopamine (da) and noradrenaline (na) and their major metabolites in individual rats 30 min after the administration of two different inhibitors of tyrosine hydroxylase, alpha-methyl-p-tyrosine (alpha-mt) and 3-iodo-l-tyrosine (mit). |
1984-06-20 |
2023-08-12 |
rat |
| F Cesselin, L Pique, X Bertagna, C Benlot, J Antréassian, M F Proeschel, F Girard, F Zogbi, J C Legrand, J P Luto. Simultaneous evaluation of the catecholamine pathway and three opioid peptide-producing systems in human pheochromocytomas. Neuropeptides. vol 4. issue 2. 1984-06-14. PMID:6144074. |
tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) activities, dopamine (da), noradrenaline (na), adrenaline (a), met 5-enkephalin (met-enk), leu5-enkephalin (leu-enk), dynorphin (dyn) and beta-endorphin (beta-end) were measured simultaneously in ten human pheochromocytomas = 1 - th activity was highly variable, from 22 to 2220 u/g tissue. |
1984-06-14 |
2023-08-12 |
human |
| T H McNeill, L L Koek, J W Haycoc. Age-correlated changes in dopaminergic nigrostriatal perikarya of the C57BL/6NNia mouse. Mechanisms of ageing and development. vol 24. issue 3. 1984-06-11. PMID:6143863. |
this study examined nigrostriatal (a9) and mesolimbic (a10) dopamine neurons for qualitative age-correlated changes using fluorescence histochemistry for catecholamines and immunocytochemical techniques for the catecholamine-synthesizing enzyme, tyrosine hydroxylase. |
1984-06-11 |
2023-08-12 |
mouse |
| A H Anton, R S Crumrine, R C Stern, R J Izan. Inhibition of catecholamine biosynthesis by carbidopa and metyrosine in neuroblastoma. Pediatric pharmacology (New York, N.Y.). vol 3. issue 2. 1984-06-11. PMID:6425794. |
in three patients with neuroblastoma and high circulating levels of dopamine and dopa, we interfered pharmacologically with catecholamine biosynthesis either at the tyrosine hydroxylase or dopa decarboxylase step in an attempt to 1) improve the efficacy of antitumor therapy and 2) avoid the potential arrythmogenic interaction between elevated circulating catecholamines and an halogenated hydrocarbon anesthetic during surgery. |
1984-06-11 |
2023-08-12 |
Not clear |
| B J Everitt, T Hökfelt, L Terenius, K Tatemoto, V Mutt, M Goldstei. Differential co-existence of neuropeptide Y (NPY)-like immunoreactivity with catecholamines in the central nervous system of the rat. Neuroscience. vol 11. issue 2. 1984-05-30. PMID:6144080. |
the distribution of neuropeptide y immunoreactive cell bodies in relation to various types of catecholamine-containing cell bodies in the rat brain was analyzed immunohistochemically using antisera to tyrosine hydroxylase, dopamine beta-hydroxylase and phenylethanolamine n-methyltransferase. |
1984-05-30 |
2023-08-12 |
rat |
| J Gu, J M Polak, J M Allen, W M Huang, M N Sheppard, K Tatemoto, S R Bloo. High concentrations of a novel peptide, neuropeptide Y, in the innervation of mouse and rat heart. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 32. issue 5. 1984-05-30. PMID:6546942. |
the distribution of npy-containing nerves paralleled that of noradrenergic fibers, demonstrated by the use of antibodies to the catecholamine-converting enzymes tyrosine hydroxylase and dopamine beta-hydroxylase. |
1984-05-30 |
2023-08-12 |
mouse |
| S I Hari. Locus ceruleus lesion by local 6-hydroxydopamine infusion causes marked and specific destruction of noradrenergic neurons, long-term depletion of norepinephrine and the enzymes that synthesize it, and enhanced dopaminergic mechanisms in the ipsilateral cerebral cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 4. issue 3. 1984-05-04. PMID:6142931. |
such lesion is accompanied by a marked and long-term depletion of norepinephrine and comparable loss of activity of its synthesizing enzymes, dopamine beta-hydroxylase and tyrosine hydroxylase, in the ipsilateral cerebral cortex. |
1984-05-04 |
2023-08-12 |
Not clear |