| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Schnabel, M Metzger, S Jiang, H C Hemmings, P Greengard, K Brau. Localization of dopamine D1 receptors and dopaminoceptive neurons in the chick forebrain. The Journal of comparative neurology. vol 388. issue 1. 1997-12-22. PMID:9364244. |
the distributions of dopamine d1 receptors, dopaminoceptive neurons, and catecholaminergic fibers were investigated in the forebrain of the domestic chick by using d1 receptor autoradiography and immunohistochemical detection of d1 receptor protein (d1rp), the dopamine- and camp-regulated phosphoprotein darpp-32, and tyrosine hydroxylase (th). |
1997-12-22 |
2023-08-12 |
chicken |
| S M Hersch, H Yi, C J Heilman, R H Edwards, A I Leve. Subcellular localization and molecular topology of the dopamine transporter in the striatum and substantia nigra. The Journal of comparative neurology. vol 388. issue 2. 1997-12-12. PMID:9368838. |
double immunocytochemistry demonstrated dat colocalization with two other markers of nigrostriatal terminals, tyrosine hydroxylase and d2 dopamine receptors. |
1997-12-12 |
2023-08-12 |
Not clear |
| J W Gibb, L Bush, G R Hanso. Exacerbation of methamphetamine-induced neurochemical deficits by melatonin. The Journal of pharmacology and experimental therapeutics. vol 283. issue 2. 1997-12-08. PMID:9353379. |
methamphetamine (meth), administered in large, repeated doses, compromises the dopaminergic and serotonergic systems as indicated by prolonged suppression of tyrosine hydroxylase and tryptophan hydroxylase activity and concurrent decreases in the content of dopamine and 5-hydroxytryptamine. |
1997-12-08 |
2023-08-12 |
rat |
| J W Gibb, L Bush, G R Hanso. Exacerbation of methamphetamine-induced neurochemical deficits by melatonin. The Journal of pharmacology and experimental therapeutics. vol 283. issue 2. 1997-12-08. PMID:9353379. |
rats were treated with meth and/or melatonin and trytophan hydroxylase activity and 5-hydroxytryptamine content were assessed; tyrosine hydroxylase activity and dopamine content were also measured. |
1997-12-08 |
2023-08-12 |
rat |
| D J Swanson, E Zellmer, E J Lewi. The homeodomain protein Arix interacts synergistically with cyclic AMP to regulate expression of neurotransmitter biosynthetic genes. The Journal of biological chemistry. vol 272. issue 43. 1997-11-28. PMID:9341190. |
transcription of the neurotransmitter biosynthetic genes tyrosine hydroxylase and dopamine beta-hydroxylase (dbh) is regulated by cell type-specific transcription factors, including the homeoprotein arix, and second messengers, including cyclic amp. |
1997-11-28 |
2023-08-12 |
Not clear |
| G Eisenhofer, A Aneman, P Friberg, D Hooper, L Fåndriks, H Lonroth, B Hunyady, E Meze. Substantial production of dopamine in the human gastrointestinal tract. The Journal of clinical endocrinology and metabolism. vol 82. issue 11. 1997-11-25. PMID:9360553. |
this study assessed the contribution of mesenteric organs (gastrointestinal tract, spleen, and pancreas) to the total body production of dopamine in humans and examined the presence of the rate-limiting enzyme for dopamine synthesis, tyrosine hydroxylase, in gastrointestinal tissues. |
1997-11-25 |
2023-08-12 |
human |
| H Wang, A Moriwaki, J B Wang, G R Uhl, V M Picke. Ultrastructural immunocytochemical localization of mu-opioid receptors in dendritic targets of dopaminergic terminals in the rat caudate-putamen nucleus. Neuroscience. vol 81. issue 3. 1997-11-24. PMID:9316027. |
we examined the cellular and subcellular bases for this interaction in the rat caudate-putamen nucleus by dual immunocytochemical labelling for mu-opioid receptors and tyrosine hydroxylase, a marker mainly for dopamine in this region. |
1997-11-24 |
2023-08-12 |
rat |
| M A Mena, M J Casarejos, A Carazo, C L Paíno, J García de Yébene. Glia protect fetal midbrain dopamine neurons in culture from L-DOPA toxicity through multiple mechanisms. Journal of neural transmission (Vienna, Austria : 1996). vol 104. issue 4-5. 1997-11-21. PMID:9295168. |
protective effects were evaluated according to the number of tyrosine hydroxylase immunoreactive cells, high affinity dopamine uptake and levels of quinones. |
1997-11-21 |
2023-08-12 |
Not clear |
| S R Wachtel, C Bencsics, U J Kan. Role of aromatic L-amino acid decarboxylase for dopamine replacement by genetically modified fibroblasts in a rat model of Parkinson's disease. Journal of neurochemistry. vol 69. issue 5. 1997-11-20. PMID:9349551. |
these findings indicate that not only is there sufficient aromatic l-amino acid decarboxylase near striatal grafts producing l-dopa, but also the close proximity of the enzyme to tyrosine hydroxylase is detrimental for optimal dopamine production. |
1997-11-20 |
2023-08-12 |
rat |
| S R Wachtel, C Bencsics, U J Kan. Role of aromatic L-amino acid decarboxylase for dopamine replacement by genetically modified fibroblasts in a rat model of Parkinson's disease. Journal of neurochemistry. vol 69. issue 5. 1997-11-20. PMID:9349551. |
this is most likely due to feedback inhibition of tyrosine hydroxylase by dopamine. |
1997-11-20 |
2023-08-12 |
rat |
| P Pastuszko, D F Wilso. Activation of tyrosine hydroxylase in striatum of newborn piglets in response to hypocapnic ischemia and recovery. Advances in experimental medicine and biology. vol 411. 1997-10-20. PMID:9269412. |
the present study describes the effect of hypocapnic ischemia caused by hyperventilation on striatal levels of dopamine, dopac, hva and activity of tyrosine hydroxylase in striatal synaptosomes isolated from the brain of newborn piglets. |
1997-10-20 |
2023-08-12 |
Not clear |
| C D Richards, T Shiroyama, S T Kita. Electrophysiological and immunocytochemical characterization of GABA and dopamine neurons in the substantia nigra of the rat. Neuroscience. vol 80. issue 2. 1997-10-17. PMID:9284356. |
the neurons recorded in the pars reticulata were identified as either gaba or dopamine neurons: neurons were considered to be gaba neurons if they were immunopositive for glutamate decarboxylase, whereas those neurons which were immunopositive for tyrosine hydroxylase were considered to be dopaminergic. |
1997-10-17 |
2023-08-12 |
rat |
| T Nagatsu, H Ichinos. GTP cyclohydrolase I gene, dystonia, juvenile parkinsonism, and Parkinson's disease. Journal of neural transmission. Supplementum. vol 49. 1997-10-03. PMID:9266429. |
gtp cyclohydrolase i is the rate-limiting enzyme for the biosynthesis of tetrahydrobiopterin, which is the cofactor for tyrosine hydroxylase, the rate-limiting enzyme for dopamine biosynthesis. |
1997-10-03 |
2023-08-12 |
Not clear |
| B K Jin, L Iacovitt. Dopamine differentiation factors produce partial motor recovery in 6-hydroxydopamine lesioned rats. Neurobiology of disease. vol 2. issue 1. 1997-10-02. PMID:8980004. |
in parallel with behavioural recovery, striatal tyrosine hydroxylase (th) activity, dopamine (da) and dihydroxy-phenyl-acetic acid (dopac) levels recovered in a dose-dependent manner in all treated rats when compared to controls. |
1997-10-02 |
2023-08-12 |
human |
| N Y Choksi, A Hussain, R G Boot. 2-Phenylaminoadenosine stimulates dopamine synthesis in rat forebrain in vitro and in vivo via adenosine A2 receptors. Brain research. vol 761. issue 1. 1997-10-01. PMID:9247078. |
using an in vivo model that measures presynaptic effects of drugs at dopamine nerve terminals, intracerebroventricular administration of pad to rats stimulated tyrosine hydroxylase activity in striatum in a manner that was selectively blocked by csc. |
1997-10-01 |
2023-08-12 |
rat |
| N Y Choksi, A Hussain, R G Boot. 2-Phenylaminoadenosine stimulates dopamine synthesis in rat forebrain in vitro and in vivo via adenosine A2 receptors. Brain research. vol 761. issue 1. 1997-10-01. PMID:9247078. |
these results suggest that pad stimulates adenylyl cyclase and tyrosine hydroxylase activity, with a corresponding increase in dopamine synthesis, by activation of presynaptic a2-type receptors in mammalian forebrain. |
1997-10-01 |
2023-08-12 |
rat |
| K Matsuura, H Makino, N Ogaw. Cyclosporin A attenuates the decrease in tyrosine hydroxylase immunoreactivity in nigrostriatal dopaminergic neurons and in striatal dopamine content in rats with intrastriatal injection of 6-hydroxydopamine. Experimental neurology. vol 146. issue 2. 1997-09-19. PMID:9270064. |
cyclosporin a attenuates the decrease in tyrosine hydroxylase immunoreactivity in nigrostriatal dopaminergic neurons and in striatal dopamine content in rats with intrastriatal injection of 6-hydroxydopamine. |
1997-09-19 |
2023-08-12 |
rat |
| N Dünke. Development and organization of the retinal dopaminergic system of Ichthyophis kohtaoensis (Amphibia; Gymnophiona). Cell and tissue research. vol 289. issue 2. 1997-09-16. PMID:9211829. |
in this study, the organization and development of the dopaminergic system have been examined in the retinae of embryonic, larval, and adult i. kohtaoensis, by using an antiserum against tyrosine hydroxylase, the rate-limiting enzyme in the catecholamine synthetic pathway, and an antiserum against dopamine itself. |
1997-09-16 |
2023-08-12 |
Not clear |
| H Tong, J Zhang, Q X. [The changes of striatal dopamine levels in the brain in rat models for Parkinson's disease after gene therapy]. Zhonghua yi xue za zhi. vol 76. issue 7. 1997-09-16. PMID:9275495. |
to examine the levels of striatal dopamine and metabolic products in rat model of parkinson's disease (pd) by intracerebral grafting of the genetically modified muscle cells expressing tyrosine hydroxylase (th). |
1997-09-16 |
2023-08-12 |
rat |
| A Ota, A Nakashima, K Mori, T Nagats. Effects of dopamine on N-terminus-deleted human tyrosine hydroxylase type 1 expressed in Escherichia coli. Neuroscience letters. vol 229. issue 1. 1997-09-12. PMID:9224801. |
effects of dopamine on n-terminus-deleted human tyrosine hydroxylase type 1 expressed in escherichia coli. |
1997-09-12 |
2023-08-12 |
human |