| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Tafti, S Nishino, W Liao, W C Dement, E Migno. Mesopontine organization of cholinergic and catecholaminergic cell groups in the normal and narcoleptic dog. The Journal of comparative neurology. vol 379. issue 2. 1997-05-21. PMID:9050784. |
therefore, we sought to characterize the corresponding neuronal populations in normal and narcoleptic dogs (doberman pinscher) by using choline acetyltransferase (chat), nicotinamide adenosine dinucleotide phosphate (nadph)-diaphorase, tyrosine hydroxylase (th), and dopamine beta-hydroxylase (dbh). |
1997-05-21 |
2023-08-12 |
human |
| J W Jahng, T A Houpt, T H Joh, T C Wesse. Expression of catecholamine-synthesizing enzymes, peptidylglycine alpha-amidating monooxygenase, and neuropeptide Y mRNA in the rat adrenal medulla after acute systemic nicotine. Journal of molecular neuroscience : MN. vol 8. issue 1. 1997-05-21. PMID:9061614. |
free-floating adrenal gland sections were hybridized with 35s-labeled cdna probes for tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), phenylethanolamine n-methyltransferase (pnmt), pam, and npy. |
1997-05-21 |
2023-08-12 |
rat |
| M M Mouradian, T N Chas. Gene therapy for Parkinson's disease: an approach to the prevention or palliation of levodopa-associated motor complications. Experimental neurology. vol 144. issue 1. 1997-05-20. PMID:9126152. |
by continuously maintaining appropriate cerebral dopamine concentrations, molecular techniques which stimulate an increase in the intrastriatal activity of tyrosine hydroxylase, the rate-limiting enzyme for dopamine synthesis, might be expected to palliate parkinsonian symptoms with less risk of the disabling consequences of current therapy. |
1997-05-20 |
2023-08-12 |
Not clear |
| D A McRitchie, H R Cartwright, G M Hallida. Specific A10 dopaminergic nuclei in the midbrain degenerate in Parkinson's disease. Experimental neurology. vol 144. issue 1. 1997-05-20. PMID:9126172. |
there was a reduction in tyrosine hydroxylase immunoreactivity but no overt neurodegeneration in other a10 regions, suggesting the disease may also influence the production of dopamine in some surviving neurons. |
1997-05-20 |
2023-08-12 |
Not clear |
| D E Millhorn, R Raymond, L Conforti, W Zhu, D Beitner-Johnson, T Filisko, M B Genter, S Kobayashi, M Pen. Regulation of gene expression for tyrosine hydroxylase in oxygen sensitive cells by hypoxia. Kidney international. vol 51. issue 2. 1997-05-19. PMID:9027733. |
gene expression of tyrosine hydroxylase (th), the rate-limiting enzyme in the biosynthesis of dopamine, is stimulated by reduced o2 tension in both type i cells and pc12 cells. |
1997-05-19 |
2023-08-12 |
Not clear |
| M J Bannon, C J Whitt. Age-related and regional differences in dopamine transporter mRNA expression in human midbrain. Neurology. vol 48. issue 4. 1997-05-15. PMID:9109886. |
the age-related decline in dat mrna was due to both a decrease in the abundance of dat mrna per dopamine cell as well as a decrease in the total number of dopamine cells expressing dat mrna, although tyrosine hydroxylase expression was less affected. |
1997-05-15 |
2023-08-12 |
human |
| M Revuelta, M Romero-Ramos, J L Venero, F Millan, A Machado, J Can. Less induced 1-methyl-4-phenylpyridinium ion neurotoxicity on striatal slices from guinea-pigs fed with a vitamin C-deficient diet. Neuroscience. vol 77. issue 1. 1997-05-02. PMID:9044384. |
in view of the higher resistance of the ascorbic acid-deficient animals to the neurotoxicity elicited by mpp+, additional dopaminergic parameters were also measured in striatal tissue from ascorbic acid-deficient animals in the absence of mpp+, including levels of dopamine and its metabolites, tyrosine hydroxylase activity and dopamine uptake, with the aim of finding an explanation for this unexpected result. |
1997-05-02 |
2023-08-12 |
Not clear |
| M Revuelta, M Romero-Ramos, J L Venero, F Millan, A Machado, J Can. Less induced 1-methyl-4-phenylpyridinium ion neurotoxicity on striatal slices from guinea-pigs fed with a vitamin C-deficient diet. Neuroscience. vol 77. issue 1. 1997-05-02. PMID:9044384. |
while dopamine levels and tyrosine hydroxylase activity remained close to control levels, dopamine uptake was significantly reduced in striatal synaptosomes from ascorbic acid-deficient animals as compared with control animals. |
1997-05-02 |
2023-08-12 |
Not clear |
| H Moukhles, O Bosler, J P Bolam, A Vallée, D Umbriaco, M Geffard, G Douce. Quantitative and morphometric data indicate precise cellular interactions between serotonin terminals and postsynaptic targets in rat substantia nigra. Neuroscience. vol 76. issue 4. 1997-04-29. PMID:9027876. |
the combination of serotonin immunocytochemistry with tyrosine hydroxylase immunolabelling of dopamine neurons reveals that 20% of the serotonin synaptic contacts in the pars reticulata are on dopamine dendrites and 6% are on a type of unlabelled dendrite characterized by its peculiarly high cytoplasmic content of microtubules. |
1997-04-29 |
2023-08-12 |
rat |
| D C German, E L Nelson, C L Liang, S G Speciale, C M Sinton, P K Sonsall. The neurotoxin MPTP causes degeneration of specific nucleus A8, A9 and A10 dopaminergic neurons in the mouse. Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration. vol 5. issue 4. 1997-04-24. PMID:9117541. |
seven days later, dopamine concentrations were measured in the striatum using high performance liquid chromatography, and midbrain dopaminergic neurons were identified using an antibody against tyrosine hydroxylase. |
1997-04-24 |
2023-08-12 |
mouse |
| Y Watanabe, T Harada, T Ito, Y Ishiguro, H Ando, T Seo, S Kobayashi, M Takahashi, Y Nimur. ret Proto-oncogene product is a useful marker of lineage determination in the development of the enteric nervous system in rats. Journal of pediatric surgery. vol 32. issue 1. 1997-04-17. PMID:9021562. |
a polyclonal antibody against ret proto-oncogene product (c-ret protein) and various monoclonal antibodies against neural markers (tyrosine hydroxylase, dopamine beta hydroxylase, microtubule-associated protein 5, microtubule-associated protein 2 and 160-kd neurofilaments) were used to identify neural crest-derived cells in rat embryos (10.5 to 15.5 days' gestation) and adult rats using a double immunostaining method. |
1997-04-17 |
2023-08-12 |
rat |
| U Ungethüm, Y Chen, J Gross, B Bjelke, P Bolme, P Eneroth, J Heldt, C F Loidl, M Herrera-Marschitz, K Andersso. Effects of perinatal asphyxia on the mesostriatal/mesolimbic dopamine system of neonatal and 4-week-old male rats. Experimental brain research. vol 112. issue 3. 1997-04-15. PMID:9007542. |
the present study was undertaken in order to study the effects of perinatal asphyxia on tyrosine hydroxylase (th) activity, dopamine levels and turnover, and dopamine metabolites (3,4-dihydroxyphenylacetic acid, dopac, homovanillic acid, hva, and 3-methoxytyramine, 3-mt, analyzed by high-performance liquid chromatography, hplc) measured in the basal ganglia of the 20- to 40-min-old newborn and 4-week-old male rat. |
1997-04-15 |
2023-08-12 |
rat |
| B Bjelke, M Goldstein, B Tinner, C Andersson, S R Sesack, H W Steinbusch, J Y Lew, X He, S Watson, B Tengroth, K Fux. Dopaminergic transmission in the rat retina: evidence for volume transmission. Journal of chemical neuroanatomy. vol 12. issue 1. 1997-04-11. PMID:9001947. |
in double immunolabelling experiments, a mismatch as well as a match was demonstrated in the rat retina between tyrosine hydroxylase (th) and dopamine (da) immunoreactive (ir) terminals and cell bodies and dopamine d2 receptor-like ir cell bodies and processes. |
1997-04-11 |
2023-08-12 |
rat |
| T L Horvat. Suprachiasmatic efferents avoid phenestrated capillaries but innervate neuroendocrine cells, including those producing dopamine. Endocrinology. vol 138. issue 3. 1997-04-07. PMID:9048641. |
as fluorogold labeling resulted in dense immunopositive granules without diffuse cytoplasmic labeling, selected sections were further immunostained for cytoplasmic tyrosine hydroxylase (dopamine). |
1997-04-07 |
2023-08-12 |
Not clear |
| T A Jenkins, F A Mendelsohn, S Y Cha. Angiotensin-converting enzyme modulates dopamine turnover in the striatum. Journal of neurochemistry. vol 68. issue 3. 1997-04-07. PMID:9048778. |
levels of dopamine d1 and d2 receptors and of preprotachykinin and tyrosine hydroxylase mrnas were unchanged after angiotensin-converting enzyme inhibition. |
1997-04-07 |
2023-08-12 |
rat |
| B Goheen Robillard, J N Kott, L E Westru. Electron microscopy of colocalization of GABA and tyrosine hydroxylase expression in rat olfactory bulb transplants. Experimental neurology. vol 143. issue 2. 1997-04-07. PMID:9056385. |
deafferentation or functional odor deprivation of the normal ob causes a loss of tyrosine hydroxylase (th) (the rate limiting enzyme in the dopamine synthesis pathway) expression within the jg cell population, but appears to have no effect on gaba levels. |
1997-04-07 |
2023-08-12 |
rat |
| F Vaglini, C Pardini, M Cavalletti, R Maggio, G U Corsin. L-deprenyl fails to protect mesencephalic dopamine neurons and PC12 cells from the neurotoxic effect of 1-methyl-4-phenylpyridinium ion. Brain research. vol 741. issue 1-2. 1997-04-02. PMID:9001706. |
on the fifth day after l-deprenyl and mpp+ exposition, cells were washed free of drugs, and the following day they were tested for dopamine uptake, intracellular dopamine content and tyrosine hydroxylase immunoreactivity. |
1997-04-02 |
2023-08-12 |
mouse |
| F Vaglini, C Pardini, M Cavalletti, R Maggio, G U Corsin. L-deprenyl fails to protect mesencephalic dopamine neurons and PC12 cells from the neurotoxic effect of 1-methyl-4-phenylpyridinium ion. Brain research. vol 741. issue 1-2. 1997-04-02. PMID:9001706. |
the fall in dopamine uptake and intracellular dopamine content, and the diminution of tyrosine hydroxylase immunoreactivity observed in cells pretreated with l-deprenyl and then given mpp+ were not significantly different from the values observed in cells treated with mpp+ alone. |
1997-04-02 |
2023-08-12 |
mouse |
| A Kupsch, J Sautter, J Schwarz, P Riederer, M Gerlach, W H Oerte. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in non-human primates is antagonized by pretreatment with nimodipine at the nigral, but not at the striatal level. Brain research. vol 741. issue 1-2. 1997-04-02. PMID:9001722. |
in common marmosets mptp induced severe parkinsonian symptoms, a pronounced dopamine depletion in the caudate-putamen (more than 99% of control) and a loss of tyrosine hydroxylase immunoreactive cells in the substantia nigra (50% percent of control) 7 days after mptp-administration. |
1997-04-02 |
2023-08-12 |
mouse |
| A Kupsch, J Sautter, J Schwarz, P Riederer, M Gerlach, W H Oerte. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in non-human primates is antagonized by pretreatment with nimodipine at the nigral, but not at the striatal level. Brain research. vol 741. issue 1-2. 1997-04-02. PMID:9001722. |
pretreatment with nimodipine (120 mg pellets) did neither attenuate the behavioural impairments in mptp-treated animals nor antagonize the striatal neurotoxin-induced dopamine depletion, but almost completely prevented (in a dose-dependent manner) the mptp-induced decrease of nigral tyrosine hydroxylase immunoreactive cells. |
1997-04-02 |
2023-08-12 |
mouse |