| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Gorio, M L Malosio, L Vergani, A M Di Giuli. Exposure to perinatal morphine promotes developmental changes in rat striatum. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 14. issue 4. 1997-01-24. PMID:8884380. |
dopamine release may also be increased as indicated by a higher metabolism and consequent reduction of tyrosine hydroxylase mrna expression in the substantia nigra. |
1997-01-24 |
2023-08-12 |
rat |
| B Nankova, R Kvetnansky, B Hiremagalur, B Sabban, M Rusnak, E L Sabba. Immobilization stress elevates gene expression for catecholamine biosynthetic enzymes and some neuropeptides in rat sympathetic ganglia: effects of adrenocorticotropin and glucocorticoids. Endocrinology. vol 137. issue 12. 1997-01-23. PMID:8940389. |
here we examined the effect of immobilization stress and treatment with acth and glucocorticoids on messenger rna (mrna) levels for tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), preproneuropeptide y (pre-npy), and proenkephalin in rat superior cervical ganglia (scg) and in stellate ganglia. |
1997-01-23 |
2023-08-12 |
rat |
| L I Serova, E V Naumenk. Involvement of the brain catecholaminergic system in the regulation of dominant behavior. Pharmacology, biochemistry, and behavior. vol 53. issue 2. 1997-01-16. PMID:8808133. |
the role of the brain catecholaminergic system in establishing dominant-subordinate relationships in mice of different genotypes was studied using inhibitors of tyrosine hydroxylase (alpha-methyl-p-tyrosine) or of dopamine-beta-hydroxylase (fla-57) or fla-57 plus the dopamine precursor, dopa. |
1997-01-16 |
2023-08-12 |
mouse |
| B Lüdecke, P M Knappskog, P T Clayton, R A Surtees, J D Clelland, S J Heales, M P Brand, K Bartholomé, T Flatmar. Recessively inherited L-DOPA-responsive parkinsonism in infancy caused by a point mutation (L205P) in the tyrosine hydroxylase gene. Human molecular genetics. vol 5. issue 7. 1997-01-16. PMID:8817341. |
tyrosine hydroxylase (th) catalyzes the conversion of l-tyrosine to l-dihydroxyphenylalanine (l-dopa), the rate-limiting step in the biosynthesis of dopamine. |
1997-01-16 |
2023-08-12 |
human |
| D B Miller, J P O'Callagha. Neurotoxicity of d-amphetamine in the C57BL/6J and CD-1 mouse. Interactions with stress and the adrenal system. Annals of the New York Academy of Sciences. vol 801. 1997-01-08. PMID:8959030. |
our previous work demonstrated that a variety of amps, including d-meth, d-mda, d-mdma but not d-fen are able to damage dopaminergic elements of the striatum as shown by decreases in dopamine and tyrosine hydroxylase. |
1997-01-08 |
2023-08-12 |
mouse |
| E Pettersson, M Herrera-Marschitz, R Rodriguez-Puertas, Z Q Xu, Z B You, J Hughes, R P Elde, U Ungerstedt, T Hökfel. Evidence for aspartate-immunoreactive neurons in the neostriatum of the rat: modulation by the mesencephalic dopamine pathway via D1-subtype of receptor. Neuroscience. vol 74. issue 1. 1997-01-06. PMID:8843077. |
the up-regulation of dynorphin and aspartate was only observed when there was an almost complete denervation of the neostriatum as visualized with antiserum to tyrosine hydroxylase, a marker for dopamine fibres. |
1997-01-06 |
2023-08-12 |
rat |
| F Hoda, D Nicholl, P Bennett, M Arranz, K J Aitchison, A al-Chalabi, H Kunugi, H Vallada, P N Leigh, K R Chaudhuri, D A Collie. No association between Parkinson's disease and low-activity alleles of catechol O-methyltransferase. Biochemical and biophysical research communications. vol 228. issue 3. 1997-01-06. PMID:8941353. |
idiopathic parkinson's disease (ipd) is characterised by the loss of pigmented neurones in the substantia nigra, leading to reduced tyrosine hydroxylase activity and depletion of dopamine. |
1997-01-06 |
2023-08-12 |
human |
| D W Howells, G T Liberatore, J Y Wong, G A Donna. Dopaminergic responses to striatal damage. Journal of the neurological sciences. vol 139. issue 1. 1996-12-23. PMID:8836983. |
we provide evidence in a mouse model of striatal damage that surgical cavitation induces a concerted response from the dopaminergic system with proliferation of striatal presynaptic dopamine uptake sites, increased tyrosine hydroxylase activity, increased concentrations of dopamine, dihydroxyphenylacetic acid and homovanillic acid. |
1996-12-23 |
2023-08-12 |
mouse |
| D A Di Monte, J E Royland, M W Jakowec, J W Langsto. Role of nitric oxide in methamphetamine neurotoxicity: protection by 7-nitroindazole, an inhibitor of neuronal nitric oxide synthase. Journal of neurochemistry. vol 67. issue 6. 1996-12-23. PMID:8931477. |
treatment of mice with 7-ni (50 mg/kg) almost completely counteracted the loss of dopamine, 3,4-dihydroxyphenylacetic acid, and tyrosine hydroxylase immunoreactivity observed 5 days after four injections of 10 or 7.5 mg/kg meth. |
1996-12-23 |
2023-08-12 |
mouse |
| J Nguyen-Legros, E Chanut, C Versaux-Botteri, A Simon, J H Trouvi. Dopamine inhibits melatonin synthesis in photoreceptor cells through a D2-like receptor subtype in the rat retina: biochemical and histochemical evidence. Journal of neurochemistry. vol 67. issue 6. 1996-12-23. PMID:8931485. |
alpha-methyl-p-tyrosine, a competitive inhibitor of tyrosine hydroxylase, enhanced the nocturnal content of melatonin, suggesting the dopamine control of melatonin synthesis as in non-mammals. |
1996-12-23 |
2023-08-12 |
rat |
| E Koutsilieri, T S Chen, W D Rausch, P Riedere. Selegiline is neuroprotective in primary brain cultures treated with 1-methyl-4-phenylpyridinium. European journal of pharmacology. vol 306. issue 1-3. 1996-12-18. PMID:8813631. |
in the delayed scheme, selegiline (1 microm) increased dopamine content, number of tyrosine hydroxylase immunoreactive cells and astrocytes in the cultures. |
1996-12-18 |
2023-08-12 |
mouse |
| C Nyquist-Battie, P K Cochran, V R Evans, J M Hitchcock, C Una. Regulation of sympathetic presynaptic components in rat left ventricle during ligation of abdominal aorta. The American journal of physiology. vol 271. issue 4 Pt 2. 1996-12-16. PMID:8897951. |
in contrast, aortic constriction did not reduce neuropeptide y (npy), tyrosine hydroxylase, dopamine beta-hydroxylase, nervegrowth factor, and low-affinity nerve growth factor receptors at any time point. |
1996-12-16 |
2023-08-12 |
rat |
| A Freese, M J During, B L Davidson, T A Gennarelli, M G Kaplitt, E S Flamm, P J Snyde. Transfection of human lactotroph adenoma cells with an adenovirus vector expressing tyrosine hydroxylase decreases prolactin release. The Journal of clinical endocrinology and metabolism. vol 81. issue 6. 1996-12-11. PMID:8964885. |
we transfected primary cultures of human lactotroph adenoma cells with an adenovirus vector containing a cdna which encodes a human tyrosine hydroxylase, the rate-limiting enzyme in the biosynthesis of dopamine. |
1996-12-11 |
2023-08-12 |
human |
| A Freese, M J During, B L Davidson, T A Gennarelli, M G Kaplitt, E S Flamm, P J Snyde. Transfection of human lactotroph adenoma cells with an adenovirus vector expressing tyrosine hydroxylase decreases prolactin release. The Journal of clinical endocrinology and metabolism. vol 81. issue 6. 1996-12-11. PMID:8964885. |
transfection induced expression of tyrosine hydroxylase and increased production of dopamine, resulting in the predicted biologic effect of decreased prolactin secretion. |
1996-12-11 |
2023-08-12 |
human |
| A Raghunathan, G A Matthews, P J Lombroso, J R Naegel. Transient compartmental expression of a family of protein tyrosine phosphatases in the developing striatum. Brain research. Developmental brain research. vol 91. issue 2. 1996-12-06. PMID:8852369. |
tyrosine hydroxylase immunoreactive fibers from the substantia nigra form distinctive dopamine islands in the striatum during late embryonic development, and occupy the sites of future patches [23,37,38,54]. |
1996-12-06 |
2023-08-12 |
rat |
| N Y Rots, A R Cools, A Bérod, P Voorn, W Rostène, E R de Kloe. Rats bred for enhanced apomorphine susceptibility have elevated tyrosine hydroxylase mRNA and dopamine D2-receptor binding sites in nigrostriatal and tuberoinfundibular dopamine systems. Brain research. vol 710. issue 1-2. 1996-12-05. PMID:8963658. |
rats bred for enhanced apomorphine susceptibility have elevated tyrosine hydroxylase mrna and dopamine d2-receptor binding sites in nigrostriatal and tuberoinfundibular dopamine systems. |
1996-12-05 |
2023-08-12 |
rat |
| N Y Rots, A R Cools, A Bérod, P Voorn, W Rostène, E R de Kloe. Rats bred for enhanced apomorphine susceptibility have elevated tyrosine hydroxylase mRNA and dopamine D2-receptor binding sites in nigrostriatal and tuberoinfundibular dopamine systems. Brain research. vol 710. issue 1-2. 1996-12-05. PMID:8963658. |
therefore, we measured tyrosine hydroxylase (th), the rate limiting enzyme in dopamine synthesis, as well as dopamine d1 and d2 receptor mrna levels in discrete brain regions by in situ hybridization. |
1996-12-05 |
2023-08-12 |
rat |
| K Yamada, S Goto, M Yoshikawa, Y Ushi. Gabaergic transmission and tyrosine hydroxylase expression in the nigral dopaminergic neurons: an in vivo study using a reversible ischemia model of rats. Neuroscience. vol 73. issue 3. 1996-12-04. PMID:8809797. |
the authors conducted an in vivo study, using a rat striatal ischemic model, of the effect of gabaergic transmission upon the dopamine synthesizing enzyme tyrosine hydroxylase in the neurons of the substantia nigra pars compacta. |
1996-12-04 |
2023-08-12 |
rat |
| K Yamada, S Goto, M Yoshikawa, Y Ushi. Gabaergic transmission and tyrosine hydroxylase expression in the nigral dopaminergic neurons: an in vivo study using a reversible ischemia model of rats. Neuroscience. vol 73. issue 3. 1996-12-04. PMID:8809797. |
the present study revealed that the striatal ischemic lesion induced a transient down-regulation of tyrosine hydroxylase synthesis in the pars compacta neurons, which could be prevented by administration of gaba agonist, suggesting that gabaergic transmission greatly affects dopamine metabolism in these cells. |
1996-12-04 |
2023-08-12 |
rat |
| J Y Cho, N Min, L Franzen, H Bake. Rapid down-regulation of tyrosine hydroxylase expression in the olfactory bulb of naris-occluded adult rats. The Journal of comparative neurology. vol 369. issue 2. 1996-12-03. PMID:8726999. |
previous odorant deprivation studies that employed unilateral naris closure in neonatal rats demonstrated down-regulation of the catecholamine biosynthetic enzyme tyrosine hydroxylase (th) in dopamine neurons intrinsic to the olfactory bulb. |
1996-12-03 |
2023-08-12 |
rat |