| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Hertzberg, T Brosenitsch, D M Kat. Depolarizing stimuli induce high levels of dopamine synthesis in fetal rat sensory neurons. Neuroreport. vol 7. issue 1. 1996-10-17. PMID:8742459. |
to investigate the role of activity-dependent mechanisms in sensory transmitter development, we examined the effect of depolarizing stimuli on tyrosine hydroxylase expression and dopamine synthesis in cells of the fetal rat petrosal ganglion, a model of catecholaminergic sensory neurons. |
1996-10-17 |
2023-08-12 |
rat |
| T Hertzberg, T Brosenitsch, D M Kat. Depolarizing stimuli induce high levels of dopamine synthesis in fetal rat sensory neurons. Neuroreport. vol 7. issue 1. 1996-10-17. PMID:8742459. |
although dopaminergic traits are normally detectable in only 10-20% of ganglion neurones, exposure to depolarizing concentrations of potassium chloride (40 mm) or veratridine (10 microm) in culture induced tyrosine hydroxylase expression in 100% of petrosal neurons and a 10-fold increase in dopamine content. |
1996-10-17 |
2023-08-12 |
rat |
| H Ewald, O Mors, H Eiberg, T Flint, T A Krus. No evidence of linkage between manic depressive illness and the dopa decarboxylase gene or nearby region on chromosome 7p. Psychiatric genetics. vol 5. issue 4. 1996-10-11. PMID:8750358. |
we have earlier reported evidence against linkage between manic depressive illness and tyrosine hydroxylase and dopamine beta-hydroxylase. |
1996-10-11 |
2023-08-12 |
Not clear |
| J F Bowyer, P Clausing, L Schmued, D L Davies, Z Binienda, G D Newport, A C Scallet, W Slikke. Parenterally administered 3-nitropropionic acid and amphetamine can combine to produce damage to terminals and cell bodies in the striatum. Brain research. vol 712. issue 2. 1996-10-04. PMID:8814896. |
such rats showed no signs of neuronal cell degeneration in the striatum, but did show significant dopamine depletions (60% of control) and reductions in tyrosine hydroxylase immunoreactivity at 14 days postexposure. |
1996-10-04 |
2023-08-12 |
rat |
| K R Johnson, L Smith, D K Johnson, J Rhodes, E M Rinchik, M Thayer, E J Lewi. Mapping of the ARIX homeodomain gene to mouse chromosome 7 and human chromosome 11q13. Genomics. vol 33. issue 3. 1996-09-20. PMID:8661014. |
arix interacts with regulatory elements of the genes encoding the noradrenergic biosynthetic enzymes tyrosine hydroxylase and dopamine beta-hydroxylase, suggesting a role for arix in expression of the noradrenergic phenotype. |
1996-09-20 |
2023-08-12 |
mouse |
| S C Kumer, K E Vran. Intricate regulation of tyrosine hydroxylase activity and gene expression. Journal of neurochemistry. vol 67. issue 2. 1996-09-19. PMID:8764568. |
tyrosine hydroxylase catalyzes the rate-limiting step in the biosynthesis of the catecholamines dopamine, norepinephrine, and epinephrine. |
1996-09-19 |
2023-08-12 |
Not clear |
| E Josefsson, J Bergquist, R Ekman, A Tarkowsk. Catecholamines are synthesized by mouse lymphocytes and regulate function of these cells by induction of apoptosis. Immunology. vol 88. issue 1. 1996-09-12. PMID:8707341. |
the dopamine production of lymphocytes was blocked by the tyrosine hydroxylase inhibitor alpha-methyl-p-tyrosine, whereas incubation with the precursor l-dopa increased the dopamine content. |
1996-09-12 |
2023-08-12 |
mouse |
| E Grassi, M Mortilla, L Amaducci, S Pallanti, A Pazzagli, F Galassi, B M Guarnieri, C Petruzzi, F Bolino, L Ortenzi, R Nistico, S De Cataldo, A Rossi, S Sorb. No evidence of linkage between schizophrenia and D2 dopamine receptor gene locus in Italian pedigrees. Neuroscience letters. vol 206. issue 2-3. 1996-09-12. PMID:8710185. |
our purpose was to test the dopamine d2 receptor gene (drd2), the tyrosine hydroxylase (th) gene and the monoamino oxydase a (mao-a) gene for linkage to schizophrenia and bipolar disorders. |
1996-09-12 |
2023-08-12 |
Not clear |
| M Lazaroff, K Dunlap, D M Chikaraish. A CNS catecholaminergic cell line expresses voltage-gated currents. The Journal of membrane biology. vol 151. issue 3. 1996-09-10. PMID:8661508. |
cath.a cells express several differentiated neuronal characteristics including medium and light chain neurofilament proteins, synaptophysin, tyrosine hydroxylase, and dopamine beta-hydroxylase; they synthesize dopamine and norepinephrine. |
1996-09-10 |
2023-08-12 |
mouse |
| M Tanaka, Y Matsumoto, T Murakami, Y Hisa, Y Ibat. The origins of catecholaminergic innervation in the rostral ventromedial medulla oblongata of the rat. Neuroscience letters. vol 207. issue 1. 1996-09-09. PMID:8710209. |
the localization of catecholaminergic neuronal cell bodies which project to the rostral ventromedial medulla oblongata (rvm) were investigated by the combined technique with dopamine beta-hydroxylase (dbh), phenylethanolamine n-methyltransferase (pnmt) or tyrosine hydroxylase (th) immunocytochemistry and retrograde neuronal tracing method using fluorescent latex microspheres (fluospheres) injected into the center of the rvm, the nucleus raphe magnus (nrm). |
1996-09-09 |
2023-08-12 |
rat |
| T G Hastings, D A Lewis, M J Zigmon. Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 5. 1996-09-05. PMID:8700866. |
moreover, the specific loss of tyrosine hydroxylase immunoreactivity associated with dopamine injections was no longer detectable, although the nonspecific changes in cytoarchitecture were still apparent. |
1996-09-05 |
2023-08-12 |
rat |
| S Halle. [Gene therapy: technics, strategy and application]. Revue des maladies respiratoires. vol 12. issue 6. 1996-08-15. PMID:8677351. |
the transfer of genes is equally applicable in any disease where the expression of the gene in the particular tissue is more effective than systemic or local treatment with the corresponding protein (for example dopamine or tyrosine hydroxylase for parkinson's disease). |
1996-08-15 |
2023-08-12 |
Not clear |
| W S Neckameye. Multiple roles for dopamine in Drosophila development. Developmental biology. vol 176. issue 2. 1996-08-06. PMID:8660862. |
manipulation of dopamine levels by inhibition of tyrosine hydroxylase activity was accomplished in drosophila melanogaster larval instars by feeding enzyme inhibitors for a 24-hr period. |
1996-08-06 |
2023-08-12 |
mouse |
| W S Neckameye. Multiple roles for dopamine in Drosophila development. Developmental biology. vol 176. issue 2. 1996-08-06. PMID:8660862. |
these results suggest that the enzymatic function of tyrosine hydroxylase is vital and that reduced levels of dopamine result in akinesia and lethality, developmental retardation, and decreased fertility. |
1996-08-06 |
2023-08-12 |
mouse |
| P M Almqvist, E Akesson, L U Wahlberg, H Pschera, A Seiger, E Sundstro. First trimester development of the human nigrostriatal dopamine system. Experimental neurology. vol 139. issue 2. 1996-07-31. PMID:8654525. |
embryonic brain tissue was taken for analysis of tyrosine hydroxylase (th) by immunohistochemistry and western blot, and for analysis of endogenous dopamine (a) content using hplc-ed. |
1996-07-31 |
2023-08-12 |
human |
| S R Sesack, C L Snyder, D A Lewi. Axon terminals immunolabeled for dopamine or tyrosine hydroxylase synapse on GABA-immunoreactive dendrites in rat and monkey cortex. The Journal of comparative neurology. vol 363. issue 2. 1996-07-16. PMID:8642074. |
axon terminals immunolabeled for dopamine or tyrosine hydroxylase synapse on gaba-immunoreactive dendrites in rat and monkey cortex. |
1996-07-16 |
2023-08-12 |
rat |
| S R Sesack, C L Snyder, D A Lewi. Axon terminals immunolabeled for dopamine or tyrosine hydroxylase synapse on GABA-immunoreactive dendrites in rat and monkey cortex. The Journal of comparative neurology. vol 363. issue 2. 1996-07-16. PMID:8642074. |
we sought to address these issues by an immunocytochemical electron microscopic approach that combined peroxidase staining for dopamine or tyrosine hydroxylase (th) with a pre-embedding gold-silver marker for gaba. |
1996-07-16 |
2023-08-12 |
rat |
| J M Wilson, K S Kalasinsky, A I Levey, C Bergeron, G Reiber, R M Anthony, G A Schmunk, K Shannak, J W Haycock, S J Kis. Striatal dopamine nerve terminal markers in human, chronic methamphetamine users. Nature medicine. vol 2. issue 6. 1996-07-15. PMID:8640565. |
we found reduced levels of three dopamine nerve terminal markers (dopamine, tyrosine hydroxylase and the dopamine transporter) in post-mortem striatum (nucleus accumbens, caudate, putamen) of chronic methamphetamine users. |
1996-07-15 |
2023-08-12 |
human |
| C M O'Hara, A Uhland-Smith, K L O'Malley, R D Tod. Inhibition of dopamine synthesis by dopamine D2 and D3 but not D4 receptors. The Journal of pharmacology and experimental therapeutics. vol 277. issue 1. 1996-06-06. PMID:8613917. |
we have derived a model system utilizing a mouse mesencephalic cell line, mn9d, which both synthesizes and releases dopamine, to characterize the modulation of tyrosine hydroxylase activity, the rate limiting enzyme in the conversion of tyrosine to dopamine, by the d2-like receptors. |
1996-06-06 |
2023-08-12 |
mouse |
| C M O'Hara, A Uhland-Smith, K L O'Malley, R D Tod. Inhibition of dopamine synthesis by dopamine D2 and D3 but not D4 receptors. The Journal of pharmacology and experimental therapeutics. vol 277. issue 1. 1996-06-06. PMID:8613917. |
in the current study, we show that quinpirole stimulation of transfected d2 and d3, but not d4, dopamine receptors inhibited k+-stimulated tyrosine hydroxylase activity in a pertussis toxin-sensitive manner, strongly suggesting g-protein coupling as a mechanistic pathway. |
1996-06-06 |
2023-08-12 |
mouse |