| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Hao, M Ebadi, R F Pfeiffe. Selegiline protects dopaminergic neurons in culture from toxic factor(s) present in the cerebrospinal fluid of patients with Parkinson's disease. Neuroscience letters. vol 200. issue 2. 1996-06-06. PMID:8614567. |
further, selegiline, a monoamine oxidase b (mao) inhibitor (0.125-0.250 microm) enhanced the number of tyrosine hydroxylase (th)-positive neurons, augmented the high affinity uptake of dopamine (da), and averted the neurotoxic effects of csf of pd patients on rat mesencephalic neurons in culture. |
1996-06-06 |
2023-08-12 |
rat |
| J Balthazart, A Foidart, P Absil, N Harad. Effects of testosterone and its metabolites on aromatase-immunoreactive cells in the quail brain: relationship with the activation of male reproductive behavior. The Journal of steroid biochemistry and molecular biology. vol 56. issue 1-6 Spec No. 1996-05-16. PMID:8603040. |
fibers that are immunoreactive for tyrosine hydroxylase (synthesis of dopamine), dopamine beta-hydroxylase (synthesis of norepinephrine) or vasotocine have been identified in the close vicinity of aro-ir cells in the pom and retrograde tracing has identified the origin of the dopaminergic and noradrenergic innervation of these areas. |
1996-05-16 |
2023-08-12 |
rat |
| A Castaño, A Ayala, J A Rodriguez-Gomez, C P de la Cruz, E Revilla, J Cano, A Machad. Increase in dopamine turnover and tyrosine hydroxylase enzyme in hippocampus of rats fed on low selenium diet. Journal of neuroscience research. vol 42. issue 5. 1996-04-30. PMID:8600301. |
increase in dopamine turnover and tyrosine hydroxylase enzyme in hippocampus of rats fed on low selenium diet. |
1996-04-30 |
2023-08-12 |
rat |
| A Castaño, A Ayala, J A Rodriguez-Gomez, C P de la Cruz, E Revilla, J Cano, A Machad. Increase in dopamine turnover and tyrosine hydroxylase enzyme in hippocampus of rats fed on low selenium diet. Journal of neuroscience research. vol 42. issue 5. 1996-04-30. PMID:8600301. |
under these circumstances, there was an increase of dopamine turnover (4-fold) in rats fed with selenium-deficient diet with respect to controls and also an increase in the tyrosine hydroxylase activity (75.8%), which was the result of the increase of the amount of the enzyme (2-fold), without significant change in the phosphorylation of the tyrosine hydroxylase. |
1996-04-30 |
2023-08-12 |
rat |
| A Castaño, A Ayala, J A Rodriguez-Gomez, C P de la Cruz, E Revilla, J Cano, A Machad. Increase in dopamine turnover and tyrosine hydroxylase enzyme in hippocampus of rats fed on low selenium diet. Journal of neuroscience research. vol 42. issue 5. 1996-04-30. PMID:8600301. |
it is concluded that the increase in dopamine turnover seems to be associated with the induction of tyrosine hydroxylase enzyme. |
1996-04-30 |
2023-08-12 |
rat |
| D A Dartt, D M McCarthy, H J Mercer, T L Kessler, E H Chung, J D Ziesk. Localization of nerves adjacent to goblet cells in rat conjunctiva. Current eye research. vol 14. issue 11. 1996-03-27. PMID:8585938. |
tissue was sectioned and nerves localized by indirect immunofluorescence microscopy, using antibodies to synaptophysin (indicates nerve, independent of type), vasoactive intestinal peptide (vip, indicates parasympathetic nerves), tyrosine hydroxylase (th, indicates sympathetic nerves), dopamine beta-hydroxylase (dbh, indicates sympathetic nerves), phenylethanolamine-n-methyltransferase (pnmt, indicates sympathetic nerves), and calcitonin gene-related peptide (cgrp, indicates sensory nerves). |
1996-03-27 |
2023-08-12 |
rat |
| L S Leshin, R R Kraeling, T E Kise. Immunocytochemical localization of the catecholamine-synthesizing enzymes, tyrosine hydroxylase and dopamine-beta-hydroxylase, in the hypothalamus of cattle. Journal of chemical neuroanatomy. vol 9. issue 3. 1996-03-22. PMID:8588833. |
immunocytochemical staining for the presence of catecholamine synthesizing enzymes, tyrosine hydroxylase and dopamine beta-hydroxylase, was used to characterize the regional distribution of catecholaminergic neurons in the hypothalamus and adjacent areas of domestic cattle, bos taurus. |
1996-03-22 |
2023-08-12 |
cattle |
| S R Sesack, C N Bressler, D A Lewi. Ultrastructural associations between dopamine terminals and local circuit neurons in the monkey prefrontal cortex: a study of calretinin-immunoreactive cells. Neuroscience letters. vol 200. issue 1. 1996-03-19. PMID:8584271. |
sections through prefrontal area 9 of cynomolgus monkeys were processed by immunoperoxidase for tyrosine hydroxylase (th) to label dopamine varicosities and by pre-embedding immunogold for calr. |
1996-03-19 |
2023-08-12 |
monkey |
| S N Haber, H Ryoo, C Cox, W L. Subsets of midbrain dopaminergic neurons in monkeys are distinguished by different levels of mRNA for the dopamine transporter: comparison with the mRNA for the D2 receptor, tyrosine hydroxylase and calbindin immunoreactivity. The Journal of comparative neurology. vol 362. issue 3. 1996-03-12. PMID:8576447. |
subsets of midbrain dopaminergic neurons in monkeys are distinguished by different levels of mrna for the dopamine transporter: comparison with the mrna for the d2 receptor, tyrosine hydroxylase and calbindin immunoreactivity. |
1996-03-12 |
2023-08-12 |
monkey |
| G F Ball, J M Casto, J Balthazar. Autoradiographic localization of D1-like dopamine receptors in the forebrain of male and female Japanese quail and their relationship with immunoreactive tyrosine hydroxylase. Journal of chemical neuroanatomy. vol 9. issue 2. 1996-03-01. PMID:8561950. |
autoradiographic localization of d1-like dopamine receptors in the forebrain of male and female japanese quail and their relationship with immunoreactive tyrosine hydroxylase. |
1996-03-01 |
2023-08-12 |
Not clear |
| D M Yurek, W Lu, S Hipkens, S J Wiegan. BDNF enhances the functional reinnervation of the striatum by grafted fetal dopamine neurons. Experimental neurology. vol 137. issue 1. 1996-03-01. PMID:8566202. |
infusion of bdnf greatly enhanced the reinnervation of the host striatum by the engrafted dopamine neurons, as determined by tyrosine hydroxylase immunostaining, and also increased the effect of the graft on locomotor behavior induced by amphetamine administration. |
1996-03-01 |
2023-08-12 |
human |
| C Font, P V Hoogland, E Vermeulen van der Zee, J Pérez-Clausell, F Martínez-Garcí. The septal complex of the telencephalon of the lizard Podarcis hispanica. I. Chemoarchitectonical organization. The Journal of comparative neurology. vol 359. issue 1. 1996-02-27. PMID:8557841. |
histochemical and immunohistochemical techniques were used to define the distribution of zinc (timm stain), acetyl cholinesterase (achase), gamma-aminobutyric acid (gaba), tyrosine hydroxylase (th), dopamine (da), serotonin (5-ht), and two neuropeptides: leu-enkephalin (l-enk) and substance p (sp). |
1996-02-27 |
2023-08-12 |
Not clear |
| Q Y Zhou, R D Palmite. Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic. Cell. vol 83. issue 7. 1996-02-21. PMID:8548806. |
mice unable to synthesize dopamine (da) specifically in dopaminergic neurons were created by inactivating the tyrosine hydroxylase (th) gene then by restoring th function in noradrenergic cells. |
1996-02-21 |
2023-08-12 |
mouse |
| L A Arbogast, J L Voog. The responsiveness of tuberoinfundibular dopaminergic neurons to prolactin feedback is diminished between early lactation and midlactation in the rat. Endocrinology. vol 137. issue 1. 1996-02-05. PMID:8536641. |
this study examined the influence of prl feedback and the suckling stimulus on tyrosine hydroxylase (th), the rate-limiting enzyme in dopamine biosynthesis, during early and midlactation. |
1996-02-05 |
2023-08-12 |
rat |
| B Ziolkowska, G Horn, A Kupsch, V Höll. The expression of proenkephalin and prodynorphin genes and the induction of c-fos gene by dopaminergic drugs are not altered in the straitum of MPTP-treated mice. Journal of neural transmission. Parkinson's disease and dementia section. vol 9. issue 2-3. 1996-02-01. PMID:8527000. |
two weeks after systemic administration of mptp (2 x 40 mg/kg, s.c. 18h apart), the lesion of the substantia nigra (sn) could be visualised by loss of the nigral tyrosine hydroxylase (th) mrna hybridization signal and by a 91% decrease in striatal dopamine levels. |
1996-02-01 |
2023-08-12 |
mouse |
| D S Albers, P K Sonsall. Methamphetamine-induced hyperthermia and dopaminergic neurotoxicity in mice: pharmacological profile of protective and nonprotective agents. The Journal of pharmacology and experimental therapeutics. vol 275. issue 3. 1996-02-01. PMID:8531070. |
the animals were sacrificed > or = 5 days later and neostriatal tyrosine hydroxylase activity and dopamine were measured. |
1996-02-01 |
2023-08-12 |
mouse |
| Y Shiotani, S Kimura, Y Ohshige, C Yanaihara, N Yanaihar. Immunohistochemical localization of pituitary adenylate cyclase-activating polypeptide (PACAP) in the adrenal medulla of the rat. Peptides. vol 16. issue 6. 1996-02-01. PMID:8532586. |
in comparison with adjacent sections stained with antisera to catecholamine synthesizing enzymes, pacap-positive cells were immunoreactive to tyrosine hydroxylase and dopamine beta-hydroxylase, but not to phenylethanolamine-n-methyltransferase, suggesting that they were coincident with noradrenaline secreting cells. |
1996-02-01 |
2023-08-12 |
rat |
| b' P M Knappskog, T Flatmark, J Mallet, B L\\xc3\\xbcdecke, K Bartholom\\xc3\\xa. Recessively inherited L-DOPA-responsive dystonia caused by a point mutation (Q381K) in the tyrosine hydroxylase gene. Human molecular genetics. vol 4. issue 7. 1996-01-26. PMID:8528210.' |
tyrosine hydroxylase (th) catalyzes the conversion of l-tyrosine to l-dihydroxyphenylalanine (l-dopa), the rate-limiting step in the biosynthesis of dopamine. |
1996-01-26 |
2023-08-12 |
Not clear |
| H Houchi, M Azuma, K Kitamura, M Okuno, M Ok. Pituitary adenylate cyclase-activating polypeptide stimulates the synthesis of dopamine in cultured bovine adrenal chromaffin cells. Hypertension research : official journal of the Japanese Society of Hypertension. vol 18 Suppl 1. 1996-01-26. PMID:8529052. |
the peptide also stimulated the phosphorylation of tyrosine hydroxylase, the enzyme catalyzing the rate-limiting step in dopamine synthesis. |
1996-01-26 |
2023-08-12 |
cattle |
| H Houchi, M Azuma, K Kitamura, M Okuno, M Ok. Pituitary adenylate cyclase-activating polypeptide stimulates the synthesis of dopamine in cultured bovine adrenal chromaffin cells. Hypertension research : official journal of the Japanese Society of Hypertension. vol 18 Suppl 1. 1996-01-26. PMID:8529052. |
dopamine synthesis and tyrosine hydroxylase phosphorylation stimulated by the maximal effective concentration of dibutyryl camp or high k+, which activates ca2+ uptake, were further enhanced by pacap1-38. |
1996-01-26 |
2023-08-12 |
cattle |