| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Tahara, J Tsukada, Y Tomura, K i Wada, T Kusayama, N Ishii, T Yatsu, W Uchida, A Tanak. Pharmacologic characterization of the oxytocin receptor in human uterine smooth muscle cells. British journal of pharmacology. vol 129. issue 1. 2000-04-18. PMID:10694212. |
the order of potencies for peptide agonists and antagonists was: oxytocin>[asu(1,6)]-oxytocin>avp= atosiban>d(ch(2))(5)tyr(me)avp>[thr(4),gly(7)]-oxytocin>ddavp, and for nonpeptide antagonists was: l-371257>ym087>sr 49059>opc-21268>sr 121463a>opc-31260. |
2000-04-18 |
2023-08-12 |
human |
| M Kono, N Hayashi, T Samat. Molecular mechanism of the nacreous layer formation in Pinctada maxima. Biochemical and biophysical research communications. vol 269. issue 1. 2000-03-31. PMID:10694502. |
n14 is homologous to n16, recently found in the nacreous layer of p. fucata (2) and is characterized by high proportions of gly, tyr, and asn together with ng repeat sequences. |
2000-03-31 |
2023-08-12 |
Not clear |
| R F Vitor, F C Lidon, C S Carvalh. Dark stained tissues of the epicarp of encore mandarin: interactions with the production of hydroxyl radicals. Free radical research. vol 31 Suppl. 2000-03-30. PMID:10694055. |
additionally, the relative proportions of gln, thr, asp, glu and gly increased sharply, while ala and tyr decreased. |
2000-03-30 |
2023-08-12 |
Not clear |
| B Regenberg, L Düring-Olsen, M C Kielland-Brandt, S Holmber. Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Current genetics. vol 36. issue 6. 2000-03-20. PMID:10654085. |
radiolabelled amino-acid uptake measurements showed that agp1p is a general permease for most uncharged amino acids (ala, gly, ser, thr, cys, met, phe, tyr, ile, leu, val, gln and asn). |
2000-03-20 |
2023-08-12 |
Not clear |
| B Regenberg, L Düring-Olsen, M C Kielland-Brandt, S Holmber. Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Current genetics. vol 36. issue 6. 2000-03-20. PMID:10654085. |
tat2p can take up phe, trp and tyr; put4p can transport ala, gly and pro; while can1p, lyp1p and the previously uncharacterized alp1p are specific for the cationic amino acids. |
2000-03-20 |
2023-08-12 |
Not clear |
| A K Sato, J A Zarutskie, M M Rushe, A Lomakin, S K Natarajan, S Sadegh-Nasseri, G B Benedek, L J Ster. Determinants of the peptide-induced conformational change in the human class II major histocompatibility complex protein HLA-DR1. The Journal of biological chemistry. vol 275. issue 3. 2000-02-24. PMID:10636922. |
a mutant hla-dr1 protein with a substitution in the beta subunit designed to fill the p1 pocket from within the protein (gly(86) to tyr) adopted to a large extent the compact, peptide-bound conformation. |
2000-02-24 |
2023-08-12 |
human |
| L Jaramillo, F Díaz, P Hernández, H Debray, F Trigo, G Mendoza, E Zenten. Purification and characterization of an adhesin from Pasteurella haemolytica. Glycobiology. vol 10. issue 1. 2000-02-17. PMID:10570221. |
the adhesin is a protein of 68 kda, as determined by sds-page, and the most abundant amino acids constituting this protein were gly, ser, glx, and ala, and low concentrations of cys, met, and tyr residues were also found. |
2000-02-17 |
2023-08-12 |
rabbit |
| R Percudani, S Ottonell. Selection at the wobble position of codons read by the same tRNA in Saccharomyces cerevisiae. Molecular biology and evolution. vol 16. issue 12. 2000-01-31. PMID:10605116. |
however, in the case of four cognate pairs (gly: ggu/ggc; asn: aau/aac; phe: uuu/uuc; tyr: uau/ uac) all read by guanosine-starting anticodons, we found evidence for a strong selective pressure driven by translational efficiency. |
2000-01-31 |
2023-08-12 |
Not clear |
| R A Farah, G R Buchanan, C F Timmons, L Phillips, V F Fairbanks, K Snow, J D Hoye. Double heterozygosity for Hb G-San Jose [beta7(A4)Glu-->Gly] and Hb Fukuoka [beta2(NA2)His-->Tyr] in a 2 1/2-year-old girl. Hemoglobin. vol 23. issue 4. 1999-12-23. PMID:10569729. |
double heterozygosity for hb g-san jose [beta7(a4)glu-->gly] and hb fukuoka [beta2(na2)his-->tyr] in a 2 1/2-year-old girl. |
1999-12-23 |
2023-08-12 |
Not clear |
| E G Novikova, F J Eng, L Yan, Y Qian, L D Fricke. Characterization of the enzymatic properties of the first and second domains of metallocarboxypeptidase D. The Journal of biological chemistry. vol 274. issue 41. 1999-11-09. PMID:10506132. |
cleavage of a peptide with ala in the penultimate position was most efficient, with the relative order ala >/= met > ser, phe > tyr > trp > thr >/= gln, asp, leu, gly >> pro for cpd with both domains active. |
1999-11-09 |
2023-08-12 |
Not clear |
| R P Ambler, M Daniel, T E Meyer, M A Cusanovic. Amino acid sequences of two high-potential iron-sulfur proteins (HiPIPs) from the moderately halophilic purple phototrophic bacterium, Rhodospirillum salinarum. Archives of biochemistry and biophysics. vol 369. issue 1. 1999-10-05. PMID:10462450. |
prior to this study, there were only 2 absolutely conserved residues (tyr 19 and gly 75, chromatium numbering) in addition to the 4 iron-sulfur cluster binding cysteine residues among the 13 hipips sequenced to date. |
1999-10-05 |
2023-08-12 |
Not clear |
| S T Liu, G Howlett, C J Barro. Histidine-13 is a crucial residue in the zinc ion-induced aggregation of the A beta peptide of Alzheimer's disease. Biochemistry. vol 38. issue 29. 1999-09-15. PMID:10413512. |
rat abeta differs from human abeta by the substitution of gly for arg, phe for tyr, and arg for his at positions 5, 10, and 13, respectively. |
1999-09-15 |
2023-08-12 |
human |
| R Morse, K O'Hanlon, M Virji, M D Collin. Isolation of rifampin-resistant mutants of Listeria monocytogenes and their characterization by rpoB gene sequencing, temperature sensitivity for growth, and interaction with an epithelial cell line. Journal of clinical microbiology. vol 37. issue 9. 1999-09-02. PMID:10449475. |
rifampin-resistant (rif(r)) mutants arising from l. monocytogenes cultures exposed to rifampin were isolated, and by partial sequencing of their rpob genes, seven different point mutations affecting five different amino acids (473asp-->asn or gly, 479gly-->asp, 483his-->tyr or leu, 528ile-->phe, and 530ser-->tyr), which led to mics of 0.5 to 100 microg/ml for the organisms, were determined. |
1999-09-02 |
2023-08-12 |
human |
| T Hagen, C Y Zhang, L J Slieker, W K Chung, R L Leibel, B B Lowel. Assessment of uncoupling activity of the human uncoupling protein 3 short form and three mutants of the uncoupling protein gene using a yeast heterologous expression system. FEBS letters. vol 454. issue 3. 1999-08-26. PMID:10431807. |
a truncated version of uncoupling protein 3s, lacking the last three c-terminal residues, tyr, lys and gly, that are part of a carrier motif that is highly conserved among all mitochondrial carriers, had a greatly reduced uncoupling activity. |
1999-08-26 |
2023-08-12 |
human |
| H Segawa, Y Fukasawa, K Miyamoto, E Takeda, H Endou, Y Kana. Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivity. The Journal of biological chemistry. vol 274. issue 28. 1999-08-05. PMID:10391916. |
lat-2 exhibits higher affinity (km = 30-50 microm) to tyr, phe, trp, thr, asn, ile, cys, ser, leu, val, and gln and relatively lower affinity (km = 180-300 microm) to his, ala, met, and gly. |
1999-08-05 |
2023-08-12 |
rat |
| A Rauk, D Yu, J Taylor, G V Shustov, D A Block, D A Armstron. Effects of structure on alpha C-H bond enthalpies of amino acid residues: relevance to H transfers in enzyme mechanisms and in protein oxidation. Biochemistry. vol 38. issue 28. 1999-08-02. PMID:10413483. |
the results for neutral side chains with phi, psi angles approximately 180 degrees, approximately 180 degrees in ascending order, to an expected accuracy of +/-10 kj mol(-)(1), are asn 326; cystine 330; asp 332; gln 334; trp 337; arg 340; lys 340; met 343; his 344; phe 344; tyr 344; leu 344; ala 345; cys 346; ser 349; gly 350; ile 351; val 352; glu 354; thr 357; pro-cis 358; pro-trans 369. |
1999-08-02 |
2023-08-12 |
Not clear |
| K J Schleife. Stereoselective characterization of the 1,4-dihydropyridine binding site at L-type calcium channels in the resting state and the opened/inactivated state. Journal of medicinal chemistry. vol 42. issue 12. 1999-07-08. PMID:10377225. |
since all pseudoreceptor models are composed of the same six amino acid residues-thr, phe, gly, met, tyr, tyr-transition from resting to open/inactivated state may be described by one additional hydrogen bond donor interaction (thr) at the left-hand side of dhps. |
1999-07-08 |
2023-08-12 |
Not clear |
| A E Mitchell, A D Jones, R S Mercer, R B Rucke. Characterization of pyrroloquinoline quinone amino acid derivatives by electrospray ionization mass spectrometry and detection in human milk. Analytical biochemistry. vol 269. issue 2. 1999-06-15. PMID:10222004. |
ala, asp, arg, cys, gly, glu, ser, thr, trp, and tyr form ipq upon incubation with pqq. |
1999-06-15 |
2023-08-12 |
human |
| B Wang, M Ishihara, Y Egashira, T Ohta, H Sanad. Effects of various kinds of dietary amino acids on the hepatotoxic action of D-galactosamine in rats. Bioscience, biotechnology, and biochemistry. vol 63. issue 2. 1999-05-20. PMID:10192913. |
in the groups with the 10% amino acid diets, activities of ast, alt, and ldh in serum of 10% l-glutamine (gln), 10% l-asparagine (asn), and 10% l-serine (ser) groups were significantly lower than those of the control group, and in the groups with the 5% amino acid diets, those activities of 5% l-histidine (his), 5% l-tyrosine (tyr), 5% l-lysine (lys), and 5% l-glycine (gly) groups were also lower than those of the control group. |
1999-05-20 |
2023-08-12 |
rat |
| H Sakagami, Y Yokote, M Kochi, E Hara, K Akahan. Amino acid utilization during apoptosis in HL-60 cells. Anticancer research. vol 19. issue 1A. 1999-05-20. PMID:10226562. |
human promyelocytic leukemia (hl-60), human squamous carcinoma (hsc-2, hsc-4, na) and rat pheochromocytoma (pc-12) cell lines consumed nonpolar (leu, ile, val, cys, met, phe), neutral polar (gln, ser, thr, tyr) and basic polar amino acids (arg, lys, his), whereas they produced nonpolar (gly, pro, ala) and acidic polar amino acids (glu). |
1999-05-20 |
2023-08-12 |
human |