| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Saito, K Ohki, N Sakura, T Hashimot. Hydrolytic cleavage of pyroglutamyl-peptide bond. II. Effects of amino acid residue neighboring the pGlu moiety. Biological & pharmaceutical bulletin. vol 19. issue 5. 1997-01-02. PMID:8741593. |
we studied the susceptibility of the pyrrolidone moiety and the pyroglutamyl-peptide bond at pglu-x-ala-phe-oh (x = gly, ala, tyr, ile, pro, his, lys, arg, thr, ser, asp, glu and trp) to 1 n hcl or 2 m trifluoromethanesulfonic acid at 60 degrees c. here we describe the rates of the cleavage reaction of the pglu-x bond, the pyrrolidone ring-opening reaction of the pglu moiety and the hydrolysate accumulation. |
1997-01-02 |
2023-08-12 |
Not clear |
| S Saito, K Ohki, N Sakura, T Hashimot. Hydrolytic cleavage of pyroglutamyl-peptide bond. II. Effects of amino acid residue neighboring the pGlu moiety. Biological & pharmaceutical bulletin. vol 19. issue 5. 1997-01-02. PMID:8741593. |
the rank order of the susceptibility rates of the cleavage reactions was ser > pro, gly > arg, ala, glu, thr, asp > his, lys > trp, tyr, ile, and that of the ring-opening reaction was ile > tyr, trp > arg, his, lys, asp > glu > ala > pro, gly > ser > thr. |
1997-01-02 |
2023-08-12 |
Not clear |
| S Saito, K Ohki, N Sakura, T Hashimot. Hydrolytic cleavage of pyroglutamyl-peptide bond. II. Effects of amino acid residue neighboring the pGlu moiety. Biological & pharmaceutical bulletin. vol 19. issue 5. 1997-01-02. PMID:8741593. |
the rank order of the half-lives of the model peptides was pro > arg, lys, ile > his, glu > ala, tyr > asp > gly > ser > thr. |
1997-01-02 |
2023-08-12 |
Not clear |
| D G Arquès, C J Miche. A complementary circular code in the protein coding genes. Journal of theoretical biology. vol 182. issue 1. 1996-12-11. PMID:8917736. |
the trinucleotides of tzero code for 13 amino acids: ala, asn, asp, gln, glu, gly, ile, leu, lys, phe, thr, tyr and val. |
1996-12-11 |
2023-08-12 |
Not clear |
| K M Partin, M W Fleck, M L Maye. AMPA receptor flip/flop mutants affecting deactivation, desensitization, and modulation by cyclothiazide, aniracetam, and thiocyanate. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 21. 1996-11-27. PMID:8824304. |
point mutations from ser to asn, ala, asp, gly, gln, met, cys, thr, leu, val, and tyr were constructed in gluraflip. |
1996-11-27 |
2023-08-12 |
Not clear |
| Z N Karamysheva, A L Karamyshev, V N Ksenzenko, M A Nesmeianov. [Analysis of the effect of replacing Lys(-20) in the alkaline phosphatase signal peptide on secretion of this enzyme]. Biokhimiia (Moscow, Russia). vol 61. issue 4. 1996-10-28. PMID:8724791. |
this was followed by mutant protein synthesis in e. coli strains producing amber-suppressor trnas specific for tyr, gly, ala, glu, phe, his, cys, and pro. |
1996-10-28 |
2023-08-12 |
Not clear |
| Z N Karamysheva, A L Karamyshev, V N Ksenzenko, M A Nesmeianov. [Analysis of the effect of replacing Lys(-20) in the alkaline phosphatase signal peptide on secretion of this enzyme]. Biokhimiia (Moscow, Russia). vol 61. issue 4. 1996-10-28. PMID:8724791. |
his and the polar uncharged tyr is without effect, while negatively charged glu and hydrophobic ala, phe and pro residues as well as gly and cys have an inhibiting action. |
1996-10-28 |
2023-08-12 |
Not clear |
| D J Griggs, K Gensberg, L J Piddoc. Mutations in gyrA gene of quinolone-resistant Salmonella serotypes isolated from humans and animals. Antimicrobial agents and chemotherapy. vol 40. issue 4. 1996-10-24. PMID:8849216. |
substitutions analogous to a substitution of a ser to a phe at position 83 (ser83-->phe) and asp87-->gly or tyr in escherichia coli were found, as was a single novel mutation outside of the qrdr resulting in ala119-->glu. |
1996-10-24 |
2023-08-12 |
Not clear |
| B Persson, P Argo. Topology prediction of membrane proteins. Protein science : a publication of the Protein Society. vol 5. issue 2. 1996-10-17. PMID:8745415. |
intra/extracellular ratios are calculated for the residue types asn, asp, gly, phe, pro, trp, tyr, and val, preferably found on the extracellular side, and for ala, arg, cys, and lys, mostly occurring on the intracellular side. |
1996-10-17 |
2023-08-12 |
Not clear |
| P Komminoth, S Muletta-Feurer, A Soltermann, E Gemsenjäger, H Bürgi, J J Staub, E Schönle, M Fried, W Vetter, G A Spinas, P U Heit. [Detection of RET-proto-oncogene mutations in the diagnosis of Type 2 endocrine neoplasia (MEN 2)]. Schweizerische medizinische Wochenschrift. vol 126. issue 31-32. 1996-10-17. PMID:8765374. |
ten different types of mutations were identified in the men 2a/fmtc families (620 cys-->arg, 618 cys-->ser, gly, 611 cys-->tyr; 634 cys-->arg, tyr, trp, phe, ser, gly) and all 6 men 2b families had a 918 met-->thr point mutation. |
1996-10-17 |
2023-08-12 |
Not clear |
| S P Rafferty, J G Guillemette, A M Berghuis, M Smith, G D Brayer, A G Mau. Mechanistic and structural contributions of critical surface and internal residues to cytochrome c electron transfer reactivity. Biochemistry. vol 35. issue 33. 1996-09-30. PMID:8718869. |
in parallel studies, the co(phen)3(3+) oxidation kinetics of tyr, leu, ile, ala, ser, and gly variants of the phylogenetically conserved residue phe82 have been studied and correlated with previous electrochemical and kinetic results. |
1996-09-30 |
2023-08-12 |
Not clear |
| R J Bienstock, T Darden, R Wiseman, L Pedersen, J C Barret. Molecular modeling of the amino-terminal zinc ring domain of BRCA1. Cancer research. vol 56. issue 11. 1996-07-30. PMID:8653694. |
the zinc ring domain of brca1 is of particular interest because it is the location of significant and frequently occurring missense (cys(61)gly, cys(64)gly, and cys(64)tyr) and frameshift (185delag) mutations observed in several high-risk kindreds. |
1996-07-30 |
2023-08-12 |
Not clear |
| D Russo, F Arturi, H G Suarez, M Schlumberger, J A Du Villard, U Crocetti, S Filett. Thyrotropin receptor gene alterations in thyroid hyperfunctioning adenomas. The Journal of clinical endocrinology and metabolism. vol 81. issue 4. 1996-07-11. PMID:8636365. |
one mutation occurred in codon 619 (asp to gly), four in codon 623 (three were ala to ser, one ala to val substitution), two in codon 632 (both thr to ile), and two in codon 633 (asp to tyr or his). |
1996-07-11 |
2023-08-12 |
Not clear |
| V Mandiyan, R O'Brien, M Zhou, B Margolis, M A Lemmon, J M Sturtevant, J Schlessinge. Thermodynamic studies of SHC phosphotyrosine interaction domain recognition of the NPXpY motif. The Journal of biological chemistry. vol 271. issue 9. 1996-06-11. PMID:8617744. |
alteration of a leu at position -5 (with respect to tyr(p)) in the egfr peptide to gly also reduced the binding affinity (kd = 580 nm). |
1996-06-11 |
2023-08-12 |
Not clear |
| D Naor, D Fischer, R L Jernigan, H J Wolfson, R Nussino. Amino acid pair interchanges at spatially conserved locations. Journal of molecular biology. vol 256. issue 5. 1996-05-03. PMID:8601843. |
first, a pronounced division of the amino acids into two classes is displayed: lys, glu, arg, gln, asp, asn, pro, gly, thr, ser and his on the one hand, and ile, val, leu, phe, met, tyr, trp, cys and ala on the other. |
1996-05-03 |
2023-08-12 |
Not clear |
| T Cserháti, E Forgác. Binding of amino acids to the cationic surfactant cetyltrimethylammoniumbromide. Biochemistry and molecular biology international. vol 37. issue 3. 1996-04-17. PMID:8595396. |
only the binding of arg, glu, gly, leu, lys, met, nle, phe trp, tyr and val to the surfactant was observed, however, the strength of interaction was fairly low. |
1996-04-17 |
2023-08-12 |
Not clear |
| A Kikuchi, T Sakaguchi, K Miwa, Y Takamiya, H G Rammensee, Y Kaneko, M Takiguch. Binding of nonamer peptides to three HLA-B51 molecules which differ by a single amino acid substitution in the A-pocket. Immunogenetics. vol 43. issue 5. 1996-04-03. PMID:9110930. |
further analysis of peptide binding to hla-b*5102 and b*5103 molecules showed that a single amino acid substitution of tyr for his at residue 171(b*5102) and that of gly for trp at residue 167 (b*5103) has a minimum effect in hla-b51-peptide binding. |
1996-04-03 |
2023-08-12 |
human |
| M Tashiro, C B Rios, G T Montelion. Classification of amino acid spin systems using PFG HCC(CO)NH-TOCSY with constant-time aliphatic 13C frequency labeling. Journal of biomolecular NMR. vol 6. issue 2. 1996-03-27. PMID:8589609. |
when combined with 13c chemical shift information, these patterns allow identification of the following spin system types: gly, ala, thr, val, leu, ile, lys, arg, pro, long-type (i.e., gln, glu and met), ser, and amx-type (i.e., asp, asn, cys, his, phe, trp and tyr). |
1996-03-27 |
2023-08-12 |
Not clear |
| A P Kyritsis, B Zhang, W Zhang, M Xiao, H Takeshima, M L Bondy, J E Cunningham, V A Levin, J Brune. Mutations of the p16 gene in gliomas. Oncogene. vol 12. issue 1. 1996-02-20. PMID:8552400. |
however, after sequencing of individual clones, we found multiple mutations in 5 tumors involving codons 73(gcc to acc, ala to thr), 76 (gcc to gtc, ala to val), 85(gct to act, ala to thr), 98(cac to tac, his to tyr), 102 (gcg to gtg, ala to val), 106 (gtg to atg, val to met), 107 (cgc to tgc, arg to cys), 127 (gca to gta, ala to val), 128 (cgg to tgg, arg to trp) and 136 (ggc to gac, gly to asp). |
1996-02-20 |
2023-08-12 |
Not clear |
| R Schwaab, J Oldenburg, U Schwaab, D J Johnson, W Schmidt, K Olek, H H Brackman, E G Tuddenha. Characterization of mutations within the factor VIII gene of 73 unrelated mild and moderate haemophiliacs. British journal of haematology. vol 91. issue 2. 1996-02-16. PMID:8547094. |
one patient showed two different base pair alterations, the first at amino acid 469 [ala(gca-->gly(gga)] and the second at position 473 [tyr(tat)-->cys(tgt)]. |
1996-02-16 |
2023-08-12 |
Not clear |