| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W M Kazmierski, R D Ferguson, A W Lipkowski, V J Hrub. A topographical model of mu-opioid and brain somatostatin receptor selective ligands. NMR and molecular dynamics studies. International journal of peptide and protein research. vol 46. issue 3-4. 1996-02-08. PMID:8537180. |
we have refined the 1h nmr-based conformations of the mu-opioid receptor selective peptides related to somatostatin of general formula xxx-yyy1-cys-zzz-d-trp-lys(orn)5-thr-pen-thr8- nh2, where xxx, yyy, zzz are 0, d-phe and tyr for 1; 0, d-tic and tyr for 2; gly, d-tic and tyr for 3; and 0, d-phe and tic for 4, respectively, (kazmierski et al., j. |
1996-02-08 |
2023-08-12 |
Not clear |
| O Hammouda, A Gaber, N Abdel-Raou. Microalgae and wastewater treatment. Ecotoxicology and environmental safety. vol 31. issue 3. 1996-01-17. PMID:7498057. |
wastewater supported algal growth by inducing the incorporation of a significantly higher content of the individual amino acids asp, thr, ser, glu, gly, and tyr, and a markedly higher level of pro. |
1996-01-17 |
2023-08-12 |
Not clear |
| A Minnich, M Roy, A Chamberland, J Lavigne, J Davigno. New methods for rapid detection of low-density lipoprotein receptor and apolipoprotein B gene mutations causing familial hypercholesterolemia. Clinical biochemistry. vol 28. issue 3. 1995-11-07. PMID:7554246. |
other less prevalent mutations include a gene deletion of approximately 5 kb, which removes exons 2 and 3 (2% of cases) and three missense mutations: trp66-->gly (exon 3) (12%), glu207-->lys (exon 4) (3%), and cys646-->tyr (exon 14) (6%). |
1995-11-07 |
2023-08-12 |
Not clear |
| A E Postlethwaite, J M Seye. Identification of a chemotactic epitope in human transforming growth factor-beta 1 spanning amino acid residues 368-374. Journal of cellular physiology. vol 164. issue 3. 1995-09-28. PMID:7650066. |
a seven residue peptide containing residues 368-374, val tyr tyr val gly arg lys, was demonstrated to be capable of inducing chemotactic migration of human peripheral blood neutrophils, monocytes, monocyte leukemia cell line thp-1, and infant foreskin fibroblasts. |
1995-09-28 |
2023-08-12 |
human |
| M Yonezawa, M Takahata, N Banzawa, N Matsubara, Y Watanabe, H Narit. Analysis of the NH2-terminal 83rd amino acid of Escherichia coli GyrA in quinolone-resistance. Microbiology and immunology. vol 39. issue 4. 1995-09-28. PMID:7651238. |
by genetic analysis of gyra genes in a gyra temperature sensitive (ts) background, exchange of ser at the nh2-terminal 83rd position of gyra to trp, leu, phe, tyr, ala, val, and ile caused bacterial resistance to the quinolones, while exchange to gly, asn, lys, arg and asp did not confer resistance. |
1995-09-28 |
2023-08-12 |
Not clear |
| A Taralp, H Kaplan, I I Sytwu, I Vlattas, R Bohacek, A K Knap, T Hirama, C P Huber, S Hasnai. Characterization of the S3 subsite specificity of cathepsin B. The Journal of biological chemistry. vol 270. issue 30. 1995-09-05. PMID:7629112. |
five synthetic substrates containing different amino acid residues at the p3 position (acetyl-x-arg-arg-amc, where x is gly, glu, arg, val, and tyr and where amc represents 7-amindo-4-methylcoumarin) were used to investigate the s3 subsite specificity of cathepsin b. |
1995-09-05 |
2023-08-12 |
Not clear |
| A Taralp, H Kaplan, I I Sytwu, I Vlattas, R Bohacek, A K Knap, T Hirama, C P Huber, S Hasnai. Characterization of the S3 subsite specificity of cathepsin B. The Journal of biological chemistry. vol 270. issue 30. 1995-09-05. PMID:7629112. |
at ph 6.0, the specificity constant, kcat/km, for tripeptide substrate hydrolysis was observed to increase in the order glu < gly < arg < val < tyr. |
1995-09-05 |
2023-08-12 |
Not clear |
| J A Endrizzi, K Breddam, S J Remingto. 2.8-A structure of yeast serine carboxypeptidase. Biochemistry. vol 33. issue 37. 1995-05-30. PMID:7727362. |
the binding of an inhibitor, benzylsuccinic acid, suggests that the c-terminal carboxylate binding site for peptide substrates is asn 51, gly 52, glu 145, and his 397 and that the "oxyanion hole" consists of the amides of gly 53 and tyr 147. |
1995-05-30 |
2023-08-12 |
Not clear |
| T L Bullock, B Branchaud, S J Remingto. Structure of the complex of L-benzylsuccinate with wheat serine carboxypeptidase II at 2.0-A resolution. Biochemistry. vol 33. issue 37. 1995-05-30. PMID:7727364. |
one of the oxygens accepts hydrogen bonds from the amides of tyr 147 and gly 53, while the other forms a very close contact (2.3 a) with the o gamma of ser 146, forcing the side chain into a conformation alternative to that found in the resting state of the enzyme. |
1995-05-30 |
2023-08-12 |
Not clear |
| S Miura-Onai, M Yabuta, K Ohsuy. Mutational study at Ser300 position of the Escherichia coli lactose repressor. Biochemical and biophysical research communications. vol 209. issue 1. 1995-05-25. PMID:7726826. |
the substitutions at this position that exhibited repressors with the wild-type phenotype in vivo were gly, ala, ile, thr, met and cys; the other 10 substitutions examined (leu, val, tyr, trp, asp, glu, gln, his, lys and arg) resulted in the laci- phenotype. |
1995-05-25 |
2023-08-12 |
Not clear |
| D H Fremont, E A Stura, M Matsumura, P A Peterson, I A Wilso. Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 7. 1995-05-11. PMID:7708669. |
based on this structural evidence, h-2kb has at least two submotifs: one with tyr at p5 (or p6 for nonamer peptides) and a small residue at p2 (i.e., ala or gly) and another with phe at p5 and a medium-sized hydrophobic residue at p2 (i.e., ile). |
1995-05-11 |
2023-08-12 |
Not clear |
| J M Hemmingsen, K M Gernert, J S Richardson, D C Richardso. The tyrosine corner: a feature of most Greek key beta-barrel proteins. Protein science : a publication of the Protein Society. vol 3. issue 11. 1995-05-09. PMID:7703839. |
y - 2 is almost always a glycine, whose left-handed beta or very extended beta conformation helps the backbone curve around the tyr ring. |
1995-05-09 |
2023-08-12 |
Not clear |
| J M Hemmingsen, K M Gernert, J S Richardson, D C Richardso. The tyrosine corner: a feature of most Greek key beta-barrel proteins. Protein science : a publication of the Protein Society. vol 3. issue 11. 1995-05-09. PMID:7703839. |
delta 5 tyr corners have a 1-residue insertion between the gly and tyr, forming a beta-bulge. |
1995-05-09 |
2023-08-12 |
Not clear |
| K Yamaoka, K Ishii, R Edamatsu, T Ito, A Mor. Changes in specific amino acid residues and Na+, K(+)-ATPase activity in cell membranes of rat cerebral cortex by low dose X-irradiation. Physiological chemistry and physics and medical NMR. vol 26. issue 4. 1995-05-02. PMID:7700981. |
it showed no dose dependent changes in tyrosine (tyr), phenylalanine (phe) and glycine (gly). |
1995-05-02 |
2023-08-12 |
rat |
| M P Bemquerer, P Adlercreutz, M Tominag. Pepsin-catalyzed peptide synthesis in organic media: studies with free and immobilized enzyme. International journal of peptide and protein research. vol 44. issue 5. 1995-04-27. PMID:7896503. |
pepsin immobilized by adsorption onto the solid supports celite and chromosorb was employed to perform a study of secondary specificity of the enzyme in organic media through the coupling between z-x-phe-oh (x = ala, asp, glu, gly, phe, ile, val, trp and tyr) and phe-ome. |
1995-04-27 |
2023-08-12 |
Not clear |
| R A Moore, B Beckthold, S Wong, A Kureishi, L E Brya. Nucleotide sequence of the gyrA gene and characterization of ciprofloxacin-resistant mutants of Helicobacter pylori. Antimicrobial agents and chemotherapy. vol 39. issue 1. 1995-04-26. PMID:7695290. |
sequencing of the amplification product from ciprofloxacin-resistant mutants of h. pylori revealed four classes of mutations with substitutions at amino acid 87 (asn-->lys), amino acid 88 (ala-->val), and amino acid 91 (asp-->gly, -->asn, or -->tyr) and a double substitution at amino acids 91 and 97 (ala-->val). |
1995-04-26 |
2023-08-12 |
Not clear |
| J Emmerich, G Chadeuf, M Alhenc-Gelas, M Gouault-Heilman, P Toulon, J N Fiessinger, M Aiac. Molecular basis of antithrombin type I deficiency: the first large in-frame deletion and two novel mutations in exon 6. Thrombosis and haemostasis. vol 72. issue 4. 1995-03-31. PMID:7878627. |
a deletion of 105 bp causing an in-frame deletion of 35 amino acids between tyr 240 and gly 276 was found in exon 4. |
1995-03-31 |
2023-08-12 |
human |
| C A Stein, P Levantis, J S Oxfor. Sequence analysis of proviral HIV RT amplified directly by a semi-quantitative technique from AZT treated patients. Journal of medical virology. vol 44. issue 2. 1995-03-16. PMID:7531752. |
amino acid changes in rt from patients harbouring resistant strains of hiv-1 were found in positions 60 (val), 62 (ala), 93 (gly), 100 (phe), 161 (pro), 173 (asn), 177 (glu), 180 (ile), 181 (tyr), 182 (leu), 186 (asp), 194 (gln), 196 (glu), 200 (ile), 209 (val), 210 (trp), 211 (lys), and 214 (phe) in addition to those described previously. |
1995-03-16 |
2023-08-12 |
Not clear |
| M Pizza, M Domenighini, W Hol, V Giannelli, M R Fontana, M M Giuliani, C Magagnoli, S Peppoloni, R Manetti, R Rappuol. Probing the structure-activity relationship of Escherichia coli LT-A by site-directed mutagenesis. Molecular microbiology. vol 14. issue 1. 1995-02-22. PMID:7830560. |
the second group was formed by mutations that caused the collapse or prevented the assembly of the a subunit: leu-41-->phe, ala-45-->tyr or glu, val-53-->tyr, val-60-->gly, ser-68-->pro, his-70-->pro, val-97-->tyr and ser-114-->tyr. |
1995-02-22 |
2023-08-12 |
Not clear |
| A B Kulkarni, P L Collins, I Bacik, J W Yewdell, J R Bennink, J E Crowe, B R Murph. Cytotoxic T cells specific for a single peptide on the M2 protein of respiratory syncytial virus are the sole mediators of resistance induced by immunization with M2 encoded by a recombinant vaccinia virus. Journal of virology. vol 69. issue 2. 1995-02-09. PMID:7815502. |
in this study, we used two approaches to demonstrate that expression of an h-2kd-restricted nonameric peptide (ser tyr ile gly ser ile asn asn ile) corresponding to m2 residues 82 to 90 is necessary and sufficient to induce protective tcd8+ responses. |
1995-02-09 |
2023-08-12 |
mouse |