| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A P Reichl, F R Mandelbau. Proteolytic specificity of moojeni protease A isolated from the venom of Bothrops moojeni. Toxicon : official journal of the International Society on Toxinology. vol 31. issue 2. 1993-04-16. PMID:8456446. |
the tyr(16)-leu(17) and gly(20)-glu(21) cleavage sites were hydrolyzed slightly more slowly, while the peptide bonds his(5)-leu(6), his(10)-leu(11), glu(21)-arg(22), gly(23)-phe(24) and phe(24)-phe(25) were more resistant to the enzyme attack. |
1993-04-16 |
2023-08-12 |
human |
| K Hiramoto, T Kato, K Kikugaw. Generation of DNA-breaking activity in the Maillard reaction of glucose-amino acid mixtures in a solid system. Mutation research. vol 285. issue 2. 1993-03-04. PMID:7678891. |
the products of gly, his, trp, tyr, phe and cysh transformed a plasmid supercoiled dna (form i) into an open circular relaxed form (form ii) and a linear form (form iii). |
1993-03-04 |
2023-08-12 |
Not clear |
| H Norder, A M Couroucé, L O Magniu. Molecular basis of hepatitis B virus serotype variations within the four major subtypes. The Journal of general virology. vol 73 ( Pt 12). 1993-01-25. PMID:1469353. |
these were at positions 134 (phe instead of tyr), 143 (thr instead of ser), 159 (ala instead of gly), 161 (tyr instead of phe) and 168 (val instead of ala). |
1993-01-25 |
2023-08-11 |
Not clear |
| S Karlin, P Buche. Correlation analysis of amino acid usage in protein classes. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 24. 1993-01-19. PMID:1465457. |
our correlation analysis reveals three major tendencies: (i) charge compensation reflected by the high correlation of basic with acidic residues; (ii) the positive correlations of functionally and structurally similar amino acids including many pairs of hydrophobic amino acids, all pairs of aromatic amino acids, the anionic pair (glutamate and aspartate), but not the cationic pair (lysine and arginine), moderately the hydroxyl pair (serine and threonine), the small amino acids (glycine and alanine), and many (but not all) of those having high values in the dayhoff substitutability matrix (characteristics such as amino acid polarity or codon usage agreement, except for the wobble position, do not necessarily imply significant positive correlations); (iii) a widespread negative correlation of the aggregate strong codon group amino acids (ala, gly, pro) versus the weak codon group amino acids (lys, ile, tyr, asn, phe). |
1993-01-19 |
2023-08-11 |
human |
| Orekhov VYu, G V Abdulaeva, Musina LYu, A S Arsenie. 1H-15N-NMR studies of bacteriorhodopsin Halobacterium halobium. Conformational dynamics of the four-helical bundle. European journal of biochemistry. vol 210. issue 1. 1992-12-30. PMID:1332860. |
in order to assign the observed cross-peaks, a selective 15n-labeling of amino acid residues (tyr, phe, trp, lys, gly, leu, val or ile) was carried out and 1h-15n-nmr spectra of bacteriorhodopsin and its fragments c1 (residues (72-231), c2 (residues 1-71), b1 (residues 1-155) and bp2 (residues 163-231) were investigated. |
1992-12-30 |
2023-08-11 |
Not clear |
| D Shah, A Schneider, S Babler, R Gandhi, E Van Noord, E Ches. Alkylation of tryptophan during deprotection of Tmob-protected carboxamide side chains. Peptide research. vol 5. issue 4. 1992-12-23. PMID:1421810. |
alkylation of tryptophan occurred during the synthesis of a 19-amino acid peptide of the following sequence: tyr ala ala gln asn arg arg gly leu asp leu leu phe trp glu gln gly gly leu. |
1992-12-23 |
2023-08-11 |
Not clear |
| P E Fraser, J T Nguyen, H Inouye, W K Surewicz, D J Selkoe, M B Podlisny, D A Kirschne. Fibril formation by primate, rodent, and Dutch-hemorrhagic analogues of Alzheimer amyloid beta-protein. Biochemistry. vol 31. issue 44. 1992-12-08. PMID:1420187. |
as controls, we examined a reverse primate sequence [pm*(40-1)] and an extensively substituted primate peptide [c(1-40); with glu3-->arg, arg5-->glu, asp7-->val, his13-->lys, lys16-->his, val18-->asp, phe19-->ser, phe20-->tyr, ser26-->pro, ala30-->val, ile31-->ala, met35-->norleu, gly38-->ile, val39-->ala, and val40-->gly]. |
1992-12-08 |
2023-08-11 |
human |
| K Yamasaki, Y Muto, Y Ito, M Wälchli, T Miyazawa, S Nishimura, S Yokoyam. A 1H-15N NMR study of human c-Ha-ras protein: biosynthetic incorporation of 15N-labeled amino acids. Journal of biomolecular NMR. vol 2. issue 1. 1992-12-02. PMID:1422147. |
in order to resolve overlapping cross peaks, selective 15n-labeling of one or two types of amino acid residues (ala, arg, asx, glx, gly, his, ile, leu, lys, met, phe, ser, thr, tyr and/or val) was carried out using appropriate e. coli mutant strains. |
1992-12-02 |
2023-08-11 |
human |
| E Ronne-Engström, L Hillered, R Flink, B Spännare, U Ungerstedt, H Carlso. Intracerebral microdialysis of extracellular amino acids in the human epileptic focus. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 12. issue 5. 1992-09-21. PMID:1506452. |
extracellular levels of aspartate (asp), glutamate (glu), serine (ser), asparagine (asn), glycine (gly), threonine (thr), arginine (arg), alanine (ala), taurine (tau), tyrosine (tyr), phenylalanine (phe), isoleucine (ileu), and leucine (leu) were monitored by using intracerebral microdialysis in seven patients with medically intractable epilepsy, undergoing epilepsy surgery. |
1992-09-21 |
2023-08-11 |
human |
| E S Dzhafaro. [Study of the structure of human serum albumin, liberated from fatty acids, by a tritium marker method]. Molekuliarnaia biologiia. vol 26. issue 1. 1992-09-18. PMID:1508166. |
defatted hsa was shown to be characterized a higher accessibility of asx, glx, thr, ser, gly, pro, ile, tyr residues while the other residues remain unchanged. |
1992-09-18 |
2023-08-11 |
human |
| Y Kawakami, T Ohga, C Shimamoto, N Satoh, S Ohmor. Determination of free N-acetylamino acids in biological samples and N-terminal acetylamino acids of proteins. Journal of chromatography. vol 576. issue 1. 1992-09-17. PMID:1500458. |
n-acetyl derivatives of asn, gln, ser, thr, gly, ala, tyr, pro, met, val, ile and leu as well as n-formyl-met could be separated and identified in the same chromatographic run. |
1992-09-17 |
2023-08-11 |
rat |
| K P Soteriadou, M S Remoundos, M C Katsikas, A K Tzinia, V Tsikaris, C Sakarellos, S J Tzarto. The Ser-Arg-Tyr-Asp region of the major surface glycoprotein of Leishmania mimics the Arg-Gly-Asp-Ser cell attachment region of fibronectin. The Journal of biological chemistry. vol 267. issue 20. 1992-08-14. PMID:1629196. |
single residue substitution peptide analogues showed that indeed tyr and gly can be alternatively substituted in the sryd- and rgds-containing peptides of gp63 and fibronectin, respectively, without major effects on their antibody binding capacity. |
1992-08-14 |
2023-08-11 |
Not clear |
| P S Brzović, Y Sawa, C C Hyde, E W Miles, M F Dun. Evidence that mutations in a loop region of the alpha-subunit inhibit the transition from an open to a closed conformation in the tryptophan synthase bienzyme complex. The Journal of biological chemistry. vol 267. issue 18. 1992-08-06. PMID:1618800. |
single substitutions of phe for glu at position 49, leu for gly at position 51, or tyr for asp at position 60 in the alpha-subunit strongly alter the observed steady state and pre-steady state inhibitory effects of the alpha-subunit-specific ligand alpha-glycerophosphate (gp) on the plp-dependent beta-reaction. |
1992-08-06 |
2023-08-11 |
Not clear |
| G Y Bakalkin, A B Rakhmaninova, V K Akparov, A A Volodin, V V Ovchinnikov, R A Sarkisya. Amino acid sequence pattern in the regulatory peptides. International journal of peptide and protein research. vol 38. issue 6. 1992-07-29. PMID:1668097. |
these properties are as follows: increased content of certain residues (gly, pro, phe, arg, tyr, met and trp) as well as an increased rate of occurrence of certain pairs of residue as compared with proteins, a random sequence of residues and "nonregulatory" peptides. |
1992-07-29 |
2023-08-11 |
Not clear |
| T Fujiwara, E Tsuji, Y Misumi, N Takami, Y Ikehar. Selective cell-surface expression of dipeptidyl peptidase IV with mutations at the active site sequence. Biochemical and biophysical research communications. vol 185. issue 2. 1992-07-21. PMID:1351722. |
when tyr632 was substituted, one mutant (tyr----phe) was expressed on the surface, whereas the others (tyr----gly or leu) were intracellularly retained. |
1992-07-21 |
2023-08-11 |
Not clear |
| G Van der Kraak, K Suzuki, R E Peter, H Itoh, H Kawauch. Properties of common carp gonadotropin I and gonadotropin II. General and comparative endocrinology. vol 85. issue 2. 1992-07-14. PMID:1601254. |
these subunits contain different n-terminal amino acids (tyr and gly for gth i; tyr and ser for gth ii). |
1992-07-14 |
2023-08-11 |
Not clear |
| M Jadot, W M Canfield, W Gregory, S Kornfel. Characterization of the signal for rapid internalization of the bovine mannose 6-phosphate/insulin-like growth factor-II receptor. The Journal of biological chemistry. vol 267. issue 16. 1992-07-06. PMID:1317852. |
val29 could be replaced by other large hydrophobic residues (phe, leu, ile, or met) with no loss of activity, but the presence of ala, gly, arg, gln, or tyr in this position inactivated the signal. |
1992-07-06 |
2023-08-11 |
cattle |
| M Ishikawa, H Iijima, R Satake-Ishikawa, H Tsumura, A Iwamatsu, T Kadoya, Y Shimada, H Fukamachi, K Kobayashi, S Matsuk. The substitution of cysteine 17 of recombinant human G-CSF with alanine greatly enhanced its stability. Cell structure and function. vol 17. issue 1. 1992-06-23. PMID:1375132. |
the cys17 of rhg-csf was substituted with gly, ala, ser, ile, tyr, arg, and pro, or deleted using site-directed mutagenesis in order to improve its thermostability. |
1992-06-23 |
2023-08-11 |
mouse |
| C de Céspedes, J G Thoene, K Lowler, H N Christense. Leucine and tissue distribution of bulky and small neutral amino acids in rats: dissociation between transport and insulin-mediated effects. Journal of inherited metabolic disease. vol 15. issue 1. 1992-06-17. PMID:1583869. |
in the present study a decrease in the plasma concentration of ile, val, phe, tyr, met, ala, pro and gly was observed after the intraperitoneal injection of leu to weanling rats. |
1992-06-17 |
2023-08-11 |
rat |
| Y Shimohigashi, K Sakaguchi, H Sakamoto, M Waki, T Cost. Opioid activities of morphiceptin-like peptides latent in various natural proteins. Peptide research. vol 3. issue 5. 1992-04-16. PMID:1966866. |
seven morphiceptin-like peptides with the h-tyr-pro-phe-xxx-nh2 sequence, where xxx denotes the selected amino acids (ala, asp, gly, gln, lys, thr and tyr), have been synthesized. |
1992-04-16 |
2023-08-11 |
Not clear |