| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Shimohigashi, K Sakaguchi, H Sakamoto, M Waki, T Cost. Opioid activities of morphiceptin-like peptides latent in various natural proteins. Peptide research. vol 3. issue 5. 1992-04-16. PMID:1966866. |
for the mu opioid receptors to which morphiceptin binds specifically and selectively, analogs with xxx = asp, lys, ala, thr, gln, tyr and gly showed a considerably weaker binding affinity than morphiceptin. |
1992-04-16 |
2023-08-11 |
Not clear |
| M D Hanigan, C C Calvert, E J DePeters, B L Reis, R L Baldwi. Kinetics of amino acid extraction by lactating mammary glands in control and sometribove-treated Holstein cows. Journal of dairy science. vol 75. issue 1. 1992-04-08. PMID:1541729. |
extractions of asn, his, thr, arg, tyr, met, cystathionine, cystine, ile, phe, orn, glu, gly, tau, cit, leu, and val were correlated linearly with arterial concentrations (r2 greater than .15) of each aa. |
1992-04-08 |
2023-08-11 |
Not clear |
| M D Hanigan, C C Calvert, E J DePeters, B L Reis, R L Baldwi. Kinetics of amino acid extraction by lactating mammary glands in control and sometribove-treated Holstein cows. Journal of dairy science. vol 75. issue 1. 1992-04-08. PMID:1541729. |
extractions of asp, glu, ser, asn, gly, gln, tau, his, cit, thr, pro, tyr, val, cystine, ile, leu, trp, orn, and lys also were correlated with arteriovenous differences of met. |
1992-04-08 |
2023-08-11 |
Not clear |
| I Kumagai, F Sunada, S Takeda, K Miur. Redesign of the substrate-binding site of hen egg white lysozyme based on the molecular evolution of C-type lysozymes. The Journal of biological chemistry. vol 267. issue 7. 1992-04-02. PMID:1537843. |
on the basis of the molecular evolution of hen egg white, human, and turkey lysozymes, three replacements (trp62 with tyr, asn37 with gly, and asp101 with gly) were introduced into the active-site cleft of hen egg white lysozyme by site-directed mutagenesis. |
1992-04-02 |
2023-08-11 |
human |
| I Kumagai, F Sunada, S Takeda, K Miur. Redesign of the substrate-binding site of hen egg white lysozyme based on the molecular evolution of C-type lysozymes. The Journal of biological chemistry. vol 267. issue 7. 1992-04-02. PMID:1537843. |
however, the combination of asn37----gly (n37g) replacement with asp101----gly (d101g) and trp62----tyr (w62y) conversions enhanced bacteriolytic activity much more than each single mutation and restored hydrolytic activity toward glycol chitin. |
1992-04-02 |
2023-08-11 |
human |
| J C Carrington, K L Herndo. Characterization of the potyviral HC-pro autoproteolytic cleavage site. Virology. vol 187. issue 1. 1992-03-12. PMID:1736533. |
substitutions of tyr (p4), val (p2), gly (p1), and gly (p1') were found to eliminate or nearly eliminate proteolysis. |
1992-03-12 |
2023-08-11 |
Not clear |
| C K Sung, X L Han, A Brunetti, B Maddux, R Yamamoto-Honda, I D Goldfin. Regulation of biological functions by an insulin receptor monoclonal antibody in insulin receptor beta-subunit mutants. Biochemistry. vol 31. issue 1. 1992-02-25. PMID:1731870. |
we then combined the use of this monoclonal antibody with cells expressing insulin receptors with mutations in the beta-subunit tyrosine kinase domain; two of atp binding site mutants v1008 (gly----val) and m1030 (lys----met) and one triple-tyrosine autophosphorylation site mutant f3 (tyr----phe at 1158, 1162, and 1163). |
1992-02-25 |
2023-08-11 |
human |
| G Deferrari, G Garibotto, C Robaudo, S Saffioti, R Pontremoli, A Tizianell. Renal metabolism of amino acids in early insulin-dependent diabetes mellitus. The Journal of diabetic complications. vol 5. issue 2-3. 1992-02-21. PMID:1770010. |
after aa ingestion in c, renal extraction of most eaas, mainly bcaas, lys, and thr, occurs; pro extraction also increases and a significant uptake of gly, glu, asp, orn, and tyr takes place. |
1992-02-21 |
2023-08-11 |
Not clear |
| K M Carvalho, C Joudiou, H Boussetta, A M Leseney, P Cohe. A peptide-hormone-inactivating endopeptidase in Xenopus laevis skin secretion. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 1. 1992-02-12. PMID:1729723. |
this enzyme, which has an apparent molecular mass of 100 kda, performs a selective cleavage at the xaa-phe, xaa-leu, or xaa-ile bond (xaa = ser, phe, tyr, his, or gly) of a number of peptide hormones, including atrial natriuretic factor, substance p, angiotensin ii, bradykinin, somatostatin, neuromedins b and c, and litorin. |
1992-02-12 |
2023-08-11 |
xenopus_laevis |
| K Gonzalez, J Cunnick, D Takemot. Retinal cyclic-GMP phosphodiesterase gamma-subunit: identification of functional residues in the inhibitory region. Biochemical and biophysical research communications. vol 181. issue 3. 1992-02-07. PMID:1662493. |
the following peptides exhibited a decreased ability to inhibit pde alpha/beta: all were from pde gamma # 63-87; pde gamma tyr 84----gly, pde gamma phe 73----gly and pde gamma gln 83----gly. |
1992-02-07 |
2023-08-11 |
Not clear |
| E S Dzhafaro. [Conformational transitions of human serum albumin depending on pH. Study using tritium markers]. Molekuliarnaia biologiia. vol 25. issue 5. 1992-01-28. PMID:1753965. |
in was shown that the f-form in comparison top the n-form is characterized by more high accessibility of ser, ala, ile, tyr, phe, his, arg, pro, val and phe residues and in the b-form tyr, ser, arg, gly, ile, phe and pro residues turn to be highly accessible. |
1992-01-28 |
2023-08-11 |
human |
| C A Fierke, T L Calderone, J F Kreb. Functional consequences of engineering the hydrophobic pocket of carbonic anhydrase II. Biochemistry. vol 30. issue 46. 1991-12-20. PMID:1657158. |
twelve amino acid substitutions of varying size and hydrophobicity were constructed at val 143 in human carbonic anhydrase ii (including gly, ser, cys, asn, asp, leu, ile, his, phe and tyr) to examine the catalytic roles of the hydrophobic pocket in the active site of this enzyme. |
1991-12-20 |
2023-08-11 |
human |
| R S Alexander, S K Nair, D W Christianso. Engineering the hydrophobic pocket of carbonic anhydrase II. Biochemistry. vol 30. issue 46. 1991-12-20. PMID:1932029. |
the obliteration of a well-defined pocket in the val-143----phe and val-143----tyr mutants results in significantly diminished enzyme activity [(5 x 10(4))-fold and (3 x 10(5))-fold, respectively]; however, the activity of the val-143----his mutant is diminished less (10(2)-fold), and deepening the pocket in the val-143----gly mutant results in only a 2-fold decrease in activity [fierke et al., 1991 (preceding paper in this issue)]. |
1991-12-20 |
2023-08-11 |
human |
| K Paul, M K Morell, T J Andrew. Mutations in the small subunit of ribulosebisphosphate carboxylase affect subunit binding and catalysis. Biochemistry. vol 30. issue 41. 1991-11-20. PMID:1911767. |
substitutions of conserved amino acid residues at positions 14 (ala, val, gly, or asp instead of thr) and 17 (cys instead of tyr), which make important contacts with conserved large-subunit residues, were introduced by site-directed mutagenesis. |
1991-11-20 |
2023-08-11 |
Not clear |
| D R McKelvey, C L Brooks, M Mokotof. A CHARMM analysis of the conformations of the metastasis-inhibiting laminin pentapeptide. Journal of protein chemistry. vol 10. issue 3. 1991-11-04. PMID:1910458. |
in this conformation the arginine side chain acts to hold tyr, ile, and gly in a partial right-handed alpha helix. |
1991-11-04 |
2023-08-11 |
mouse |
| V Döring, M Schleicher, A A Noege. Dictyostelium annexin VII (synexin). cDNA sequence and isolation of a gene disruption mutant. The Journal of biological chemistry. vol 266. issue 26. 1991-10-21. PMID:1832674. |
by cloning the cdna coding for the membrane associated actin-binding protein p24, we identified a repetitive sequence motif consisting of the amino acids gly, tyr, pro, gln which is characteristic for a gene family in dictyostelium discoideum. |
1991-10-21 |
2023-08-11 |
Not clear |
| K Yoshida, A Oshima, M Shimmoto, Y Fukuhara, H Sakuraba, N Yanagisawa, Y Suzuk. Human beta-galactosidase gene mutations in GM1-gangliosidosis: a common mutation among Japanese adult/chronic cases. American journal of human genetics. vol 49. issue 2. 1991-09-06. PMID:1907800. |
the other two infantile patients had different mutations; a 123 gly(ggg)----arg(agg) mutation in one patient and a 316 tyr(tat)----cys(tgt) mutation in the other. |
1991-09-06 |
2023-08-11 |
human |
| S E Shephard, I Meier, W K Lut. Alkylating potency of nitrosated amino acids and peptides. IARC scientific publications. issue 105. 1991-08-29. PMID:1855885. |
the relative overall alkylating potency was 23:10:5:4:2:1: for trp, met, his, tyr, phe and gly, respectively. |
1991-08-29 |
2023-08-11 |
human |
| C N Trotman, A M Manning, L Moens, W P Tat. The polymeric hemoglobin molecule of Artemia. Interpretation of translated cDNA sequence of nine domains. The Journal of biological chemistry. vol 266. issue 21. 1991-08-23. PMID:1856210. |
features found to be characteristic of artemia globin and present in all nine domains were phe at b10, tyr at c4, gly at f5, phe at g5 and gly at h22. |
1991-08-23 |
2023-08-11 |
Not clear |
| T Muro, T Murakami, Y Tominaga, T Tokuyama, S Okad. Purification and some properties of protease I having transfer action from Streptomyces griseus var. alcalophilus. Agricultural and biological chemistry. vol 55. issue 2. 1991-08-20. PMID:1368689. |
protease i catalyzed the transfer reaction synthesizing the hydroxamic acids of hydrophobic, acidic, basic, and small aliphatic amino acids such as phe, tyr, leu, asp, glu, arg, lys, ala, and gly. |
1991-08-20 |
2023-08-11 |
Not clear |