| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Till Opatz, Rob M J Liskam. Synthesis and screening of libraries of synthetic tripodal receptor molecules with three different amino acid or peptide arms: identification of iron binders. Journal of combinatorial chemistry. vol 4. issue 4. 2002-08-06. PMID:12099844. |
in the synthesis of the first library, the two outer arms consisted of amino acid ala, arg, asp, gln, gly, lys, phe, ser, tyr, or val and the middle arm consisted of amino acid asn, glu, his, leu, or pro. |
2002-08-06 |
2023-08-12 |
Not clear |
| Till Opatz, Rob M J Liskam. Synthesis and screening of libraries of synthetic tripodal receptor molecules with three different amino acid or peptide arms: identification of iron binders. Journal of combinatorial chemistry. vol 4. issue 4. 2002-08-06. PMID:12099844. |
the first outer arm consisted of amino acid(s) ala, arg, gln, phe, or ser, the second outer arm consisted of amino acid(s) asp, gly, lys, tyr, or val, and the middle arm consisted of amino acid(s) asn, glu, his, leu, or pro, leading to a 27 000 member library of synthetic tripodal receptor molecules. |
2002-08-06 |
2023-08-12 |
Not clear |
| Laura J V Piddoc. Fluoroquinolone resistance in Salmonella serovars isolated from humans and food animals. FEMS microbiology reviews. vol 26. issue 1. 2002-07-10. PMID:12007640. |
these mutations confer substitutions analogous to escherichia coli ser83-->phe and asp87-->gly or tyr, or a novel mutation resulting in ala119-->glu or val. |
2002-07-10 |
2023-08-12 |
Not clear |
| L Li, Y Q. A novel amino acid position in hemagglutinin glycoprotein of measles virus is responsible for hemadsorption and CD46 binding. Archives of virology. vol 147. issue 4. 2002-06-26. PMID:12038687. |
after adaptation, fu strain has an asn to tyr substitution at position 481 and ima strain has two substitutions--an asp to asn at position 14 and a ser to gly at position 546, smd strain also has a ser to gly substitution at position 546. |
2002-06-26 |
2023-08-12 |
monkey |
| L Li, Y Q. A novel amino acid position in hemagglutinin glycoprotein of measles virus is responsible for hemadsorption and CD46 binding. Archives of virology. vol 147. issue 4. 2002-06-26. PMID:12038687. |
site-directed mutagenesis of the h genes were performed to confirm that the substitution of ser --> gly at position 546 and asn --> tyr at position 481 in the h protein were responsible for hemadsorption alteration. |
2002-06-26 |
2023-08-12 |
monkey |
| Valentin A Ustinov, Edward F Plo. Delineation of the key amino acids involved in neutrophil inhibitory factor binding to the I-domain supports a mosaic model for the capacity of integrin alphaMbeta 2 to recognize multiple ligands. The Journal of biological chemistry. vol 277. issue 21. 2002-06-24. PMID:11880366. |
these analyses ultimately identified asp(149), arg(151), gly(207), tyr(252), and glu(258) as critical for nif binding. |
2002-06-24 |
2023-08-12 |
Not clear |
| A A Owji, Z Khoshdel, F Sanea, M R Panjehshahin, M Shojaee Fard, D M Smith, H A Coppock, M A Ghatei, S R Bloo. Effects of intracerebroventricular injection of glucagon like peptide-1 and its related peptides on serotonin metabolism and on levels of amino acids in the rat hypothalamus. Brain research. vol 929. issue 1. 2002-06-12. PMID:11852032. |
in this study the actions of glp-1 and its related peptides, exendin-4 (glp-1r agonist), exendin (9-39) (glp-1r antagonist) and glp-1 (9-36) amide (the major glp-1 metabolite) on levels of serotonin (5-ht), 5-hydroxyindolacetic acid (5-hiaa) and amino acids (glu, asp, gln, gly, tyr, trp, gaba) in the hypothalamus were investigated. |
2002-06-12 |
2023-08-12 |
rat |
| John F Leite, Michael Casci. Probing the topology of the glycine receptor by chemical modification coupled to mass spectrometry. Biochemistry. vol 41. issue 19. 2002-06-03. PMID:11994009. |
of significance, nitrations at tyr 223 and tyr 228 occur within the first putative transmembrane helix (m1) of the receptor, and their labeling suggests a non-helical secondary structure for m1 for the glycine receptor. |
2002-06-03 |
2023-08-12 |
human |
| Richard J Balment, Maria A Masini, Mauro Vallarino, J Michael Conlo. Cardiovascular actions of lungfish bradykinin in the unanaesthetised African lungfish, Protopterus annectens. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 131. issue 2. 2002-05-31. PMID:11818234. |
bradykinin (bk) isolated from plasma of the african lungfish, protopterus annectens, contains four amino acid substitutions compared with bk from mammals (arg(1)-->tyr, pro(2)-->gly, pro(7)-->ala, phe(8)-->pro). |
2002-05-31 |
2023-08-12 |
Not clear |
| Tsuyoshi Saito, Yoshinao Oda, Akio Sakamoto, Ken-ichi Kawaguchi, Kazuhiro Tanaka, Shuichi Matsuda, Sadafumi Tamiya, Yukihide Iwamoto, Masazumi Tsuneyosh. APC mutations in synovial sarcoma. The Journal of pathology. vol 196. issue 4. 2002-05-28. PMID:11920741. |
the mutational sites comprised one case each at codons 1299 (gct to act, ala to thr), 1412 (gga to aga, gly to arg), and 1414 (gta to ata, val to ile), in addition to one case with double point mutations at codon 1398 (agt to aat, ser to asn) and at codon 1413 (atg to ata, met to ile), together with beta-catenin mutation at codon 32 (gac to tac, asp to tyr). |
2002-05-28 |
2023-08-12 |
Not clear |
| Yu-Chen Chen, Andras Muhlrad, Arie Shteyer, Marina Vidson, Itai Bab, Michael Chore. Bioactive pseudopeptidic analogues and cyclostereoisomers of osteogenic growth peptide C-terminal pentapeptide, OGP(10-14). Journal of medicinal chemistry. vol 45. issue 8. 2002-05-06. PMID:11931616. |
residues tyr(10), phe(12), gly(13), and gly(14) of ogp are essential for the ogp(10-14) activity. |
2002-05-06 |
2023-08-12 |
Not clear |
| Kevin B Temeyer, L Carmen Soileau, John H Pruet. Cloning and sequence analysis of a cDNA encoding Pso o II, a mite group II allergen of the sheep scab mite (Acari: Psoroptidae). Journal of medical entomology. vol 39. issue 2. 2002-04-25. PMID:11931040. |
nucleotide and translated sequences of the cdna were compared with sequences in genbank and found to be homologous to mite group ii allergens lep d ii (formerly lep d i) of lepidoglyphus destructor schrank, derfii of dermatophagoides farinae hughes, der p ii of derrmatophagoides pteronyssinus (trouessart), tyr p ii of tyrophagus putrescentiae (schrank), eur m ii of euroglyphus maynei (cooreman) and gly d ii of glycophagus domesticus (de geer). |
2002-04-25 |
2023-08-12 |
cattle |
| Ivano Eberini, Laura Calabresi, Robin Wait, Gabriella Tedeschi, Angela Pirillo, Lina Puglisi, Cesare R Sirtori, Elisabetta Gianazz. Macrophage metalloproteinases degrade high-density-lipoprotein-associated apolipoprotein A-I at both the N- and C-termini. The Biochemical journal. vol 362. issue Pt 3. 2002-04-19. PMID:11879189. |
the higher abundance of c- than n-terminally cleaved peptides agrees with data in the literature for a fully structured alpha-helix around tyr(18) compared with an unstructured region around gly(185) and gly(186). |
2002-04-19 |
2023-08-12 |
Not clear |
| John L Battiste, Renhao Li, Clare Woodwar. A highly destabilizing mutation, G37A, of the bovine pancreatic trypsin inhibitor retains the average native conformation but greatly increases local flexibility. Biochemistry. vol 41. issue 7. 2002-03-27. PMID:11841215. |
in wild-type (wt) bpti, gly 37 hn is in an unusual nh-aromatic-nh network of interactions with the ring of tyr 35 and the side chain hn of asn 44. |
2002-03-27 |
2023-08-12 |
cattle |
| Lu Liu, Michael Murray, Elizabeth Burche. Structure-activity studies of bufokinin, substance P and their C-terminal fragments at bufokinin receptors in the small intestine of the cane toad, Bufo marinus. Biochemical pharmacology. vol 63. issue 2. 2002-03-27. PMID:11841796. |
the study suggests that the full undecapeptide sequence of bufokinin is required for optimal activity, with high potency conferred by lys(1), pro(2), gly(9) and probably tyr(8). |
2002-03-27 |
2023-08-12 |
Not clear |
| D A Cochran, A J Doi. Effect of the N2 residue on the stability of the alpha-helix for all 20 amino acids. Protein science : a publication of the Protein Society. vol 10. issue 7. 2002-02-21. PMID:11420432. |
the rank order of deltadeltag((relative to ala)) is glu(-), asp(-) > ala > glu(0), leu, val, gln, thr, ile, ser, met, asp(0), his(0), arg, cys, lys, phe > asn, > gly, his(+), pro, tyr. |
2002-02-21 |
2023-08-12 |
Not clear |
| M Treger, E Westho. Statistical analysis of atomic contacts at RNA-protein interfaces. Journal of molecular recognition : JMR. vol 14. issue 4. 2001-12-19. PMID:11500966. |
the main conclusions are the following: (i) in all three groups of complexes, the most preferred amino acids (arg, asn, ser, lys) and the less preferred ones (ala, ile, leu, val) are the same; trp and cys are rarely observed (respectively 15 and 5 amino acids in the ensemble of interfaces); (ii) of the total number of amino acids located at the interfaces 22% are hydrophobic, 40% charged (positive 32%, negative 8%), 30% polar and 8% are gly; (iii) in ribosomal complexes, phosphate is preferred over ribose, which is preferred over the bases, but there is no significant preference in the other two groups; (iv) there is no significant prevalence of a base type at protein-rna interfaces, but specifically arg and lys display a preference for phosphate over ribose and bases; pro and asn prefer bases over ribose and phosphate; met, phe and tyr prefer ribose over phosphate and bases. |
2001-12-19 |
2023-08-12 |
Not clear |
| J Marie, E Richard, D Pruneau, J L Paquet, C Siatka, R Larguier, C Poncé, P Vassault, T Groblewski, B Maigret, J C Bonnafou. Control of conformational equilibria in the human B2 bradykinin receptor. Modeling of nonpeptidic ligand action and comparison to the rhodopsin structure. The Journal of biological chemistry. vol 276. issue 44. 2001-12-07. PMID:11495910. |
a detailed pharmacological analysis of receptor mutants possessing either increased constitutive activity or impaired activation or ligand recognition allowed us to propose key residues participating in intramolecular interaction networks stabilizing receptor inactive or active conformations: asn(113) and tyr(115) (tm iii), trp(256) and phe(259) (tm vi), tyr(295) (tm vii) which are homologous of the rhodopsin residues gly(120), glu(122), trp(265), tyr(268), and lys(296), respectively. |
2001-12-07 |
2023-08-12 |
human |
| T Kozaki, T Shono, T Tomita, Y Kon. Fenitroxon insensitive acetylcholinesterases of the housefly, Musca domestica associated with point mutations. Insect biochemistry and molecular biology. vol 31. issue 10. 2001-12-04. PMID:11483435. |
mutations at gly(342) and tyr(407), which are reportedly conserved in resistant strains of drosophila, were associated with the insensitivity to fenitroxon. |
2001-12-04 |
2023-08-12 |
drosophila_melanogaster |
| C M Deane, S C Lummi. The role and predicted propensity of conserved proline residues in the 5-HT3 receptor. The Journal of biological chemistry. vol 276. issue 41. 2001-12-04. PMID:11495906. |
thus five residues (gly, pro, tyr, trp, phe) and three residues (pro, tyr, phe) were found more frequently than expected before and after cis-prolines respectively, whereas five residues (val, ile, leu, asp, thr) and two residues (asp, glu) were found less frequently. |
2001-12-04 |
2023-08-12 |
Not clear |