| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J M Ling, E W Chan, A W Lam, A F Chen. Mutations in topoisomerase genes of fluoroquinolone-resistant salmonellae in Hong Kong. Antimicrobial agents and chemotherapy. vol 47. issue 11. 2004-07-06. PMID:14576119. |
thirty-two isolates had a single gyra mutation (ser83-->phe, ser83-->tyr, asp87-->asn, asp87-->tyr, or asp87-->gly), 34 had both a gyra mutation and a parc mutation (29 isolates with a parc mutation of tyr57-->ser and 5 isolates with a parc mutation of ser80-->arg). |
2004-07-06 |
2023-08-12 |
Not clear |
| Hae Sook Park, Choonmi Kim, Young Kee Kan. Preferred conformations of cyclic Ac-Cys-Pro-Xaa-Cys-NHMe peptides: a model for chain reversal and active site of disulfide oxidoreductase. Biophysical chemistry. vol 105. issue 1. 2004-05-20. PMID:12932582. |
the conformational study on cyclic ac-cys-pro-xaa-cys-nhme (ac-cpxc-nhme; x=ala, val, leu, aib, gly, his, phe, tyr, asn and ser) peptides has been carried out using the empirical conformational energy program for peptides, version 3 (ecepp/3) force field and the hydration shell model in the unhydrated and hydrated states. |
2004-05-20 |
2023-08-12 |
Not clear |
| Ling Ling Cheng, Stoytcho Stoev, Maurice Manning, Sylvain Derick, Ana Pena, Mohamed Ben Mimoun, Gilles Guillo. Design of potent and selective agonists for the human vasopressin V1b receptor based on modifications of [deamino-cys1]arginine vasopressin at position 4. Journal of medicinal chemistry. vol 47. issue 9. 2004-05-20. PMID:15084136. |
the glutamine(4) residue in [deamino-cys(1)]arginine vasopressin (davp) was replaced by a broad series of aliphatic, aromatic, polar, and charged amino acids to give the following peptides: d[gly(4)]avp (1), d[ala(4)]avp (2), d[abu(4)]avp (3), d[nva(4)]avp (4), d[nle(4)]avp (5), d[leu(4)]avp (6), d[ile(4)]avp (7), d[thi(4)]avp (8), d[phe(4)]avp (9), d[tyr(4)]avp (10), d[trp(4)]avp (11), d[asn(4)]avp (12), d[ser(4)]avp (13), d[thr(4)]avp (14), d[dap(4)]avp (15), d[dab(4)]avp (16), d[orn(4)]avp (17), d[lys(4)]avp (18), d[arg(4)]avp (19), d[har(4)]avp (20), and d[glu(4)]avp (21). |
2004-05-20 |
2023-08-12 |
human |
| Valérie Wittamer, Françoise Grégoire, Patrick Robberecht, Gilbert Vassart, David Communi, Marc Parmentie. The C-terminal nonapeptide of mature chemerin activates the chemerin receptor with low nanomolar potency. The Journal of biological chemistry. vol 279. issue 11. 2004-05-19. PMID:14701797. |
alanine-scanning mutagenesis identified residues tyr(149), phe(150), gly(152), phe(154), and phe(156) as the key positions for chemerinr activation. |
2004-05-19 |
2023-08-12 |
human |
| Gary L Juskowiak, Shawn J Stachel, Parcharee Tivitmahaisoon, David L Van Vranke. Fluorogenic peptide sequences--transformation of short peptides into fluorophores under ambient photooxidative conditions. Journal of the American Chemical Society. vol 126. issue 2. 2004-05-04. PMID:14719952. |
the bead-based peptide library was composed of the general sequence h(2)n-ala-(xxx)(6)-ala-resin, where xxx was one of nine representative amino acids: asp, gly, his, leu, lys, pro, ser, trp, and tyr. |
2004-05-04 |
2023-08-12 |
human |
| Tiesheng Shi, Stephen M Spain, Dallas L Rabenstei. Unexpectedly fast cis/trans isomerization of Xaa-Pro peptide bonds in disulfide-constrained cyclic peptides. Journal of the American Chemical Society. vol 126. issue 3. 2004-04-28. PMID:14733553. |
acyclic dithiol and cyclic disulfide forms of the peptides ac-cys-pro-xaa-cys-nh2 (xaa = phe, his, tyr, gly, and thr) and ac-cys-gly-pro-cys-nh2 and the peptide ac-ala-gly-pro-ala-nh2 were synthesized and characterized by mass spectrometry and nmr spectroscopy. |
2004-04-28 |
2023-08-12 |
Not clear |
| Maoqing Dong, Zhijun Li, Delia I Pinon, Terry P Lybrand, Laurence J Mille. Spatial approximation between the amino terminus of a peptide agonist and the top of the sixth transmembrane segment of the secretin receptor. The Journal of biological chemistry. vol 279. issue 4. 2004-04-23. PMID:14593094. |
because his(1) is critical for function, we also positioned a photolabile bpa as an amino-terminal extension, in positions -1 (rat [bpa(-1),tyr(10)]secretin-27) and -2 (rat [bpa(-2),gly(-1),tyr(10)]secretin-27). |
2004-04-23 |
2023-08-12 |
rat |
| Stéphanie Chevalier, Réjeanne Gougeon, Stuart H Kreisman, Chantal Cassis, José A Morai. The hyperinsulinemic amino acid clamp increases whole-body protein synthesis in young subjects. Metabolism: clinical and experimental. vol 53. issue 3. 2004-04-09. PMID:15015153. |
all 21 plasma aa remained in the target range; 15, including the bcaa, alanine, and glycine were within 13% of baseline, and only 6 (thr, his, arg, asn, cit, tyr) varied more (18% to 42%). |
2004-04-09 |
2023-08-12 |
human |
| R A Walker, J A Skinner, L R Ward, E J Threlfal. LightCycler gyrA mutation assay (GAMA) identifies heterogeneity in GyrA in Salmonella enterica serotypes Typhi and Paratyphi A with decreased susceptibility to ciprofloxacin. International journal of antimicrobial agents. vol 22. issue 6. 2004-03-25. PMID:14659662. |
four mutations (ser-83 to phe, asp-87 to asn, ser-83 to tyr and asp-87 to gly) have been identified in 13 strains of typhi and three strains of paratyphi a resistant to nalidixic acid (=nal(r)) and with decreased susceptibility to ciprofloxacin (=cp(l)), with the mutation ser-83 to phe predominating. |
2004-03-25 |
2023-08-12 |
Not clear |
| Jorge A Vila, Héctor A Baldoni, Daniel R Ripoll, Harold A Scherag. Unblocked statistical-coil tetrapeptides in aqueous solution: quantum-chemical computation of the carbon-13 NMR chemical shifts. Journal of biomolecular NMR. vol 26. issue 2. 2004-03-04. PMID:12766407. |
here, we carry out a cluster analysis of the ensembles of conformations generated in that study, and use them to compute the boltzmann-averaged values of the quantum-chemical (13)c chemical shifts for different amino acids in the unblocked tetrapeptides ggxa (where x stands for phe, arg, his, glu, ile, lys, gln, tyr, leu, thr, ala, gly and val). |
2004-03-04 |
2023-08-12 |
Not clear |
| Sanjay Sarkhel, Gautam R Desiraj. N-H...O, O-H...O, and C-H...O hydrogen bonds in protein-ligand complexes: strong and weak interactions in molecular recognition. Proteins. vol 54. issue 2. 2004-02-27. PMID:14696187. |
c-h...o bonds formed by gly, phe, and tyr residues are noteworthy. |
2004-02-27 |
2023-08-12 |
Not clear |
| Hiroshi Sawada, Hiroshi Nakato, Toru Togawa, Motoko Nakagoshi, Shin-Ichiro Takikawa, Kenjiro Dohke, Teruhiko Iino, Keisuke Mase, Toshio Yamamoto, Susumu Izum. Molecular cloning and characterization of a cDNA encoding a novel cuticle protein in the silkworm, Bombyx mori. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. vol 134. issue 3. 2003-12-23. PMID:12628383. |
both a typical tandem repeat (a-a-p-a/v) for cuticle protein and a unique tandem repeat with ser, ala, gly, pro, val, tyr and thr were observed in the predicted amino acid sequence of the cdna encoding bmcpa. |
2003-12-23 |
2023-08-12 |
Not clear |
| Hiroshi Sawada, Hiroshi Nakato, Toru Togawa, Motoko Nakagoshi, Shin-Ichiro Takikawa, Kenjiro Dohke, Teruhiko Iino, Keisuke Mase, Toshio Yamamoto, Susumu Izum. Molecular cloning and characterization of a cDNA encoding a novel cuticle protein in the silkworm, Bombyx mori. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. vol 134. issue 3. 2003-12-23. PMID:12628383. |
approximately 80% of the amino acids in bmcpa were composed of ser, ala, gly, pro, val and tyr. |
2003-12-23 |
2023-08-12 |
Not clear |
| U Kosior-Korzecka, R Bobowie. Changes in the level of endogenous leptin, FSH, 17beta-oestradiol and metabolites during lupin-induced increase in ovulation rate in ewes. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine. vol 50. issue 7. 2003-12-12. PMID:14633226. |
moreover, in the ewes fed lupin the plasma concentrations of glucose and nine glycogenic amino acids (gly, ala, val, met, leu, ile, tyr, phe and arg) were increased. |
2003-12-12 |
2023-08-12 |
human |
| Paul K S Chan, Chi-Kong Li, Ki-Wai Chik, Matthew M K Shing, Vincent Lee, King-Cheung Ng, Ching-Wan Lam, Jo L K Cheung, Augustine F Chen. Genetic variation of glycoproteins B and H of human herpesvirus 7 in Hong Kong. Journal of medical virology. vol 71. issue 3. 2003-12-11. PMID:12966550. |
three of these were nonsynonymous substitutions (codon 271 lys --> gln, codon 308 gly --> glu, codon 397 asn --> tyr). |
2003-12-11 |
2023-08-12 |
human |
| Michele Arienzo, Antonio De Martino, Renato Capasso, Antimo Di Maro, Augusto Parent. Analysis of carbohydrates and amino acids in vegetable waste waters by ion chromatography. Phytochemical analysis : PCA. vol 14. issue 2. 2003-12-08. PMID:12693630. |
the sugars determined were arabinose, fructose, galactose, glucose, rhamnose, xylose, galacturonic and glucuronic acids, and the amino acids were asp, glu, thr, ser, pro, gly, ala, val, met, ile, leu, tyr, phe, lys, his, arg and cys. |
2003-12-08 |
2023-08-12 |
Not clear |
| Yolanda Sáenz, Myriam Zarazaga, Laura Briñas, Fernanda Ruiz-Larrea, Carmen Torre. Mutations in gyrA and parC genes in nalidixic acid-resistant Escherichia coli strains from food products, humans and animals. The Journal of antimicrobial chemotherapy. vol 51. issue 4. 2003-12-05. PMID:12654733. |
a single change in the gyra protein was detected in all 61 nalr strains with ciprofloxacin mics leu (54), ser-83-->ala (one), ser-83-->val (one), asp-87-->asn (two), asp-87-->tyr (two) and asp-87-->gly (one). |
2003-12-05 |
2023-08-12 |
Not clear |
| Jana Charvátová, Zdenek Deyl, Václav Kasika, Vladimír Krá. Open tubular capillary electrochromatography of underivatized amino acids using Rh(III) tetrakis(phenoxyphenyl)porphyrinate as wall modifier. Journal of chromatography. A. vol 990. issue 1-2. 2003-11-20. PMID:12685594. |
regarding the sensitivity of the method, lower concentration limits of detection (lods) in the coated capillary were obtained for thr, gly, tyr, and val; the other amino acids exhibited lower lods in the uncoated capillary. |
2003-11-20 |
2023-08-12 |
Not clear |
| María-Isabel Morosini, Elena Loza, Rosa del Campo, Felisa Almaraz, Fernando Baquero, Rafael Cantó. Fluoroquinolone-resistant Streptococcus pneumoniae in Spain: activities of garenoxacin against clinical isolates including strains with altered topoisomerases. Antimicrobial agents and chemotherapy. vol 47. issue 8. 2003-09-23. PMID:12878544. |
amino acid replacements in grya (ser81-->phe or tyr), parc (ser79-->phe or tyr; asp83-->gly; lys137-->asn), and pare (ile460-->val; asp435-->asn), alone or in combination, were ascribed to the reduced garenoxacin susceptibility (mic range, 0.5 to 1 micro g/ml) found in four isolates. |
2003-09-23 |
2023-08-12 |
Not clear |
| Françoise Payan, Ruth Flatman, Sophie Porciero, Gary Williamson, Nathalie Juge, Alain Rousse. Structural analysis of xylanase inhibitor protein I (XIP-I), a proteinaceous xylanase inhibitor from wheat (Triticum aestivum, var. Soisson). The Biochemical journal. vol 372. issue Pt 2. 2003-07-22. PMID:12617724. |
gly(81), located in subsite -1 of hevamine, where the reaction intermediate is formed, is replaced by tyr(80) in xip-i. |
2003-07-22 |
2023-08-12 |
Not clear |