All Relations between th2 and nasal

Publication Sentence Publish Date Extraction Date Species
Rui Zheng, Dan Wang, Kai Wang, Wen-Xiang Gao, Qin-Tai Yang, Li-Jie Jiang, Min Zhou, Yu-Jie Cao, Jianbo Shi, Yueqi Su. Elevated expression of IL-17RB and ST2 on myeloid dendritic cells is associated with a Th2-skewed eosinophilic inflammation in nasal polyps. Clinical and translational allergy. vol 8. 2020-09-30. PMID:30519393. this study aimed to measure the expressions of il-17rb, st2 and tslpr, receptor of il-25, il-33, and tslp respectively, on myeloid dcs in nasal polyps (np) and evaluate their association with local th2 inflammation and disease severity in patients with np. 2020-09-30 2023-08-13 Not clear
Yi Wei, Renqiang Ma, Jia Zhang, Xingmei Wu, Guodong Yu, Xianting Hu, Jian Li, Zhuofu Liu, Wendong Ji, Huabin Li, Weiping We. Excessive periostin expression and Th2 response in patients with nasal polyps: association with asthma. Journal of thoracic disease. vol 10. issue 12. 2020-09-30. PMID:30746204. excessive periostin expression and th2 response in patients with nasal polyps: association with asthma. 2020-09-30 2023-08-13 Not clear
Tomoe Nishimura, Osamu Kaminuma, Mayumi Saeki, Noriko Kitamura, Akio Mori, Takachika Hiro. Suppressive effect of environmental tobacco smoke on murine Th2 cell-mediated nasal eosinophilic inflammation. Asia Pacific allergy. vol 10. issue 2. 2020-09-28. PMID:32411583. suppressive effect of environmental tobacco smoke on murine th2 cell-mediated nasal eosinophilic inflammation. 2020-09-28 2023-08-13 Not clear
Suoyi Feng, Longzhu Ju, Ziqi Shao, Mark Grzanna, Lu Jia, Ming Li. Therapeutic Effect of C-C Chemokine Receptor Type 1 (CCR1) Antagonist BX471 on Allergic Rhinitis. Journal of inflammation research. vol 13. 2020-09-28. PMID:32801828. allergic rhinitis (ar) is an immunoglobulin e (ige)-mediated inflammatory respiratory hypersensitivity characterized by elevated th2 cytokines and infiltration of inflammatory cells to nasal tissues. 2020-09-28 2023-08-13 mouse
Brandi T Johnson-Weaver, Gregory D Sempowski, Herman F Staat. Nasal peanut+ CpG immunotherapy enhances peanut-specific IFN-γ in Th2 cells and IL-10 in non-Th2 cells in mice. Allergy. vol 74. issue 11. 2020-09-03. PMID:30746720. nasal peanut+ cpg immunotherapy enhances peanut-specific ifn-γ in th2 cells and il-10 in non-th2 cells in mice. 2020-09-03 2023-08-13 mouse
Yun-Xiu Wang, Zhao-Wei Gu, Li-Ying Ha. The environmental hormone nonylphenol interferes with the therapeutic effects of G protein-coupled estrogen receptor specific agonist G-1 on murine allergic rhinitis. International immunopharmacology. vol 78. 2020-07-13. PMID:31835084. the expression of transcription factors unique to th1, th2, treg cells and cytokine levels in nasal mucosa were evaluated by real-time pcr and cytometric bead arrays. 2020-07-13 2023-08-13 mouse
Yun-Xiu Wang, Zhao-Wei Gu, Li-Ying Ha. The environmental hormone nonylphenol interferes with the therapeutic effects of G protein-coupled estrogen receptor specific agonist G-1 on murine allergic rhinitis. International immunopharmacology. vol 78. 2020-07-13. PMID:31835084. these results indicate that g-1 attenuated the nasal symptoms, serum ova-specific ige, and th2 cell immune response, whereas it enhanced treg immune response, in mice with ar. 2020-07-13 2023-08-13 mouse
Z Chen, Y Deng, F Li, B Xiao, X Zhou, Z Ta. MicroRNA-466a-3p attenuates allergic nasal inflammation in mice by targeting GATA3. Clinical and experimental immunology. vol 197. issue 3. 2020-05-06. PMID:31081939. allergic rhinitis is thought to be an allergic disease associated with immunoglobulin (ig)e-mediated immune response, characterized by increased t helper type 2 (th2) cytokine production, elevated eosinophil levels in the nasal mucosa and induced nasal secretions. 2020-05-06 2023-08-13 mouse
Neil N Patel, Vasiliki Triantafillou, Ivy W Maina, Alan D Workman, Charles C L Tong, Edward C Kuan, Peter Papagiannopoulos, John V Bosso, Nithin D Adappa, James N Palmer, Michael A Kohanski, De'Broski R Herbert, Noam A Cohe. Fungal extracts stimulate solitary chemosensory cell expansion in noninvasive fungal rhinosinusitis. International forum of allergy & rhinology. vol 9. issue 7. 2020-04-06. PMID:30892837. solitary chemosensory cells (sccs) are rare epithelial cells enriched in nasal polyps and are the primary source of interleukin-25 (il-25), an innate cytokine eliciting t-helper 2 (th2) immune response. 2020-04-06 2023-08-13 human
Y Zhang, L Derycke, G Holtappels, X D Wang, L Zhang, C Bachert, N Zhan. Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps. Allergy. vol 74. issue 1. 2020-03-20. PMID:29802623. th2 cytokines orchestrate the secretion of muc5ac and muc5b in il-5-positive chronic rhinosinusitis with nasal polyps. 2020-03-20 2023-08-13 Not clear
E Ridolo, I Martignago, S Masier. Mechanisms of allergic diseases in Otorhinolaryngology. Journal of biological regulators and homeostatic agents. vol 32. issue 1 Suppl. 1. 2019-12-09. PMID:29552867. such mechanism is responsible for continuing inflammation sustained by chemoattractants, cytokines and adhesion receptors that induce cellular infiltration of eosinophils, basophils, th2 lymphocytes and mast cells and is clinically mirrored by the prevalence of nasal congestion over sneezing, itching and rhinorrhea. 2019-12-09 2023-08-13 Not clear
Ibon Eguíluz-Gracia, Kristiina Malmstrom, Sinan Ahmed Dheyauldeen, Jouko Lohi, Antti Sajantila, Ragnhild Aaløkken, Arvind Y M Sundaram, Gregor D Gilfillan, Mika Makela, Espen S Baekkevold, Frode L Jahnse. Monocytes accumulate in the airways of children with fatal asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. vol 48. issue 12. 2019-11-14. PMID:30184280. recently, it was shown in an experimental human model of allergic rhinitis (ar) that activated monocytes rapidly accumulate in the nasal mucosa after local allergen challenge, where they promote recruitment of th2 cells and eosinophils. 2019-11-14 2023-08-13 human
Xi-Hui Fan, Lei Cheng, Ai-Hui Ya. Ameliorative effect of acetylshikonin on ovalbumin (OVA)-induced allergic rhinitis in mice through the inhibition of Th2 cytokine production and mast cell histamine release. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. vol 127. issue 10. 2019-09-17. PMID:31344274. acetylshikonin attenuated manifestation of nasal symptoms in sensitized mice and inhibited production of th2-related ova-specific ige, igg1, and th2 cell-produced il-4, il-5, il-13, and mast cell produced histamine; however, it had no effect on th1 cell-produced cytokines, like inf-γ. 2019-09-17 2023-08-13 mouse
Lisa Giovannini-Chami, Agnès Paquet, Céline Sanfiorenzo, Nicolas Pons, Julie Cazareth, Virginie Magnone, Kévin Lebrigand, Benoit Chevalier, Ambre Vallauri, Valérie Julia, Charles-Hugo Marquette, Brice Marcet, Sylvie Leroy, Pascal Barbr. The "one airway, one disease" concept in light of Th2 inflammation. The European respiratory journal. vol 52. issue 4. 2019-08-19. PMID:30190271. in line with the pathophysiological continuum described between nose and bronchus in allergic respiratory diseases, we assessed whether nasal epithelium could mirror the type 2 t-helper cell (th2) status of bronchial epithelium.nasal and bronchial cells were collected by brushing from healthy controls (c, n=13), patients with allergic rhinitis and asthma (ar, n=12), and patients with isolated allergic rhinitis (r, n=14). 2019-08-19 2023-08-13 Not clear
Lisa Giovannini-Chami, Agnès Paquet, Céline Sanfiorenzo, Nicolas Pons, Julie Cazareth, Virginie Magnone, Kévin Lebrigand, Benoit Chevalier, Ambre Vallauri, Valérie Julia, Charles-Hugo Marquette, Brice Marcet, Sylvie Leroy, Pascal Barbr. The "one airway, one disease" concept in light of Th2 inflammation. The European respiratory journal. vol 52. issue 4. 2019-08-19. PMID:30190271. the gene expression profile of nasal samples from the ar group correctly predicted the paired bronchial sample th2 status in 71% of cases. 2019-08-19 2023-08-13 Not clear
Lisa Giovannini-Chami, Agnès Paquet, Céline Sanfiorenzo, Nicolas Pons, Julie Cazareth, Virginie Magnone, Kévin Lebrigand, Benoit Chevalier, Ambre Vallauri, Valérie Julia, Charles-Hugo Marquette, Brice Marcet, Sylvie Leroy, Pascal Barbr. The "one airway, one disease" concept in light of Th2 inflammation. The European respiratory journal. vol 52. issue 4. 2019-08-19. PMID:30190271. nevertheless, nasal cells did not appear to be a reliable surrogate for the th2 response, in particular due to a more robust influence of the ifn response in 14 out of 26 nasal samples. 2019-08-19 2023-08-13 Not clear
Lisa Giovannini-Chami, Agnès Paquet, Céline Sanfiorenzo, Nicolas Pons, Julie Cazareth, Virginie Magnone, Kévin Lebrigand, Benoit Chevalier, Ambre Vallauri, Valérie Julia, Charles-Hugo Marquette, Brice Marcet, Sylvie Leroy, Pascal Barbr. The "one airway, one disease" concept in light of Th2 inflammation. The European respiratory journal. vol 52. issue 4. 2019-08-19. PMID:30190271. the th2 scores in the nose and bronchi correlated with mast cell count (both p<0.001) and number of sensitisations (p=0.006 and 0.002), while the th17 scores correlated with pmn count (p=0.006 and 0.003).the large variability in nasal cell composition and type of inflammation restricts its use as a surrogate for assessing bronchial th2 inflammation in ar patients. 2019-08-19 2023-08-13 Not clear
Yanjing Fan, Chun Hua Piao, Eunjin Hyeon, Sun Young Jung, Ji-Eun Eom, Hee Soon Shin, Chang Ho Song, Ok Hee Cha. Gallic acid alleviates nasal inflammation via activation of Th1 and inhibition of Th2 and Th17 in a mouse model of allergic rhinitis. International immunopharmacology. vol 70. 2019-08-13. PMID:30884431. gallic acid alleviates nasal inflammation via activation of th1 and inhibition of th2 and th17 in a mouse model of allergic rhinitis. 2019-08-13 2023-08-13 mouse
Yun-Fang An, Yong-Jin Wu, Xian-Hai Zeng, Li-Juan Song, Fei Ma, Wen-Jing Liao, Zhi-Qiang Liu, Gui Yang, Xiao-Wen Zhang, Zhi-Gang Liu, Chang-Qing Zhao, Ping-Chang Yan. B cell lymphoma-2-like protein-12 association with T-helper 2 inflammation in chronic rhinosinusitis with allergy. International forum of allergy & rhinology. vol 8. issue 11. 2019-08-05. PMID:30281927. t-helper 2 (th2) polarization plays a critical role in the pathogenesis of chronic rhinosinusitis (crs) with accompanying nasal allergy. 2019-08-05 2023-08-13 Not clear
Y-Y Zhang, J An, K Wang, B Han, Y-F Liu, H-L Jia, Y-S Li, L Lei, N Jia, J L. Comparative studies of mucosal humoral and cellular immune responses to 2009 pandemic H1N1 influenza virus in mice. Acta virologica. vol 63. issue 2. 2019-08-01. PMID:31230449. compared with pr8 infection, bj501 induced a more rapid increase of virus-specific iga and igg antibodies in the nasal lavage fluid and a higher ratio of igg1/igg2a, indicating a stronger th2 response to bj501 in mucosal immunity. 2019-08-01 2023-08-13 mouse