| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yung Jin Jeon, Chan Hee Gil, Jina Won, Ara Jo, Hyun Jik Ki. Symbiotic microbiome Staphylococcus aureus from human nasal mucus modulates IL-33-mediated type 2 immune responses in allergic nasal mucosa. BMC microbiology. vol 20. issue 1. 2021-09-07. PMID:33028252. |
we sought to determine the distribution of nasal microbiomes in allergic nasal mucosa and elucidate the interplay between nasal microbiome staphylococcus species and th2 cytokines in allergic rhinitis (ar) models. |
2021-09-07 |
2023-08-13 |
human |
| Brennan J Blight, Amarbir S Gill, Jorgen S Sumsion, Chelsea E Pollard, Shaelene Ashby, Gretchen M Oakley, Jeremiah A Alt, Abigail Pulsiphe. Cell Adhesion Molecules are Upregulated and May Drive Inflammation in Chronic Rhinosinusitis with Nasal Polyposis. Journal of asthma and allergy. vol 14. 2021-06-05. PMID:34079296. |
chronic rhinosinusitis with nasal polyps (crswnp) is predominantly characterized by eosinophil- and t helper 2 cell (th2)-biased inflammation. |
2021-06-05 |
2023-08-13 |
Not clear |
| Xiaofeng Gu, Feng Xiao, Wenmin Lu, Ying Xu, Xia Li, Chenjie Yu, Xinyan Cu. Nanomedicine-mediated prevention of inflammatory monocytes infiltration ameliorate ovalbumin-induced allergic rhinitis in mouse model. Autoimmunity. vol 53. issue 4. 2021-06-03. PMID:32285703. |
th2 immune cells infiltration into nasal mucosa is one of the characters of allergic rhinitis (ar). |
2021-06-03 |
2023-08-13 |
mouse |
| Yuanyuan Zhang, Wei L. Effects of oral desloratadine citrate disodium combined with physiological seawater nasal irrigation on IgE levels, IL-4, IL-6, IL-13 and IFN-γ expression and treatment of intermittent allergic rhinitis. Cellular and molecular biology (Noisy-le-Grand, France). vol 66. issue 5. 2021-06-03. PMID:33040814. |
this experiment was performed to explore the effect of oral desloratadine citrate disodium combined with physiological seawater nasal irrigation in the treatment of intermittent allergic rhinitis and its effect on serum inflammatory factors and peripheral blood th1 and th2. |
2021-06-03 |
2023-08-13 |
Not clear |
| Júlio Cláudio Sousa, Renata Margarida Etchbehere, Eduardo Arthur Rodovalho Alves, Letícia Montes Stark, Eddie Fernando Cândido Murta, Márcia Antoniazi Micheli. Interferon-α action in cytokine profile in eosinophilic nasal polyp cultures. Brazilian journal of otorhinolaryngology. vol 87. issue 3. 2021-06-02. PMID:31870738. |
in the west, approximately 80% of chronic rhinosinusitis with nasal polyps cases are characterized by a predominantly eosinophilic cell infiltrate and a th2 cytokine pattern. |
2021-06-02 |
2023-08-13 |
Not clear |
| Gwanghui Ryu, Dae Woo Ki. Th2 inflammatory responses in the development of nasal polyps and chronic rhinosinusitis. Current opinion in allergy and clinical immunology. vol 20. issue 1. 2021-05-27. PMID:31567293. |
th2 inflammatory responses in the development of nasal polyps and chronic rhinosinusitis. |
2021-05-27 |
2023-08-13 |
Not clear |
| Gwanghui Ryu, Dae Woo Ki. Th2 inflammatory responses in the development of nasal polyps and chronic rhinosinusitis. Current opinion in allergy and clinical immunology. vol 20. issue 1. 2021-05-27. PMID:31567293. |
in this review, we summarized recently updated information in the understanding of mechanisms in the development of chronic rhinosinusitis with nasal polyp (crswnp) focusing on th2 inflammation. |
2021-05-27 |
2023-08-13 |
Not clear |
| Yaqiong Zhu, Yuehui Liu, Xinhua Zhu, Zhi Wang, Meiqun Wan. Upregulation of miR-155 regulates group 2 innate lymphoid cells by targeting c-maf in allergic rhinitis. European journal of pharmacology. vol 887. 2021-05-14. PMID:32946865. |
administration of mir-155 antagomir significantly reduced the activity of ilc2s in nasal mucosa, suppressed the production of th2 cytokines in serum and nasal mucosa, and alleviated the airway inflammation and allergic symptoms in ar mice, while mir-155 agomir increased ilc2s activity and production of th2 cytokines and induced airway inflammation and allergic symptoms in control mice. |
2021-05-14 |
2023-08-13 |
mouse |
| C Yang, N Chen, X L Tang, X H Qian, C P Ca. Immunomodulatory effects of IL-33 and IL-25 in an ovalbumin-induced allergic rhinitis mouse model. Journal of biological regulators and homeostatic agents. vol 35. issue 2. 2021-05-14. PMID:33738997. |
immunomodulatory effects were evaluated by measuring nasal rubbing, sneezing occurrence, serum ova-specific antibodies, th2 immune responses, neutrophil, eosinophil and mast cell recruitment into the nasal mucosa. |
2021-05-14 |
2023-08-13 |
mouse |
| C Yang, N Chen, X L Tang, X H Qian, C P Ca. Immunomodulatory effects of IL-33 and IL-25 in an ovalbumin-induced allergic rhinitis mouse model. Journal of biological regulators and homeostatic agents. vol 35. issue 2. 2021-05-14. PMID:33738997. |
we found that treatment with anti-il-33 ab markedly reduced nasal rubbing, sneezing events, th2 immune responses, serum ova-specific ige and igg1 levels, mucosal neutrophil, eosinophil and mast cell infiltration. |
2021-05-14 |
2023-08-13 |
mouse |
| Hao Zhang, Xinhua Zhu, Xiao Liu, Yaojie Wang, Yuehui Li. Long non-coding RNA FOXD3-AS1 regulates the expression and secretion of IL-25 in nasal epithelial cells to inhibit Th2 type immunoreaction in allergic rhinitis. Molecular and cellular biochemistry. vol 473. issue 1-2. 2021-04-28. PMID:32671514. |
long non-coding rna foxd3-as1 regulates the expression and secretion of il-25 in nasal epithelial cells to inhibit th2 type immunoreaction in allergic rhinitis. |
2021-04-28 |
2023-08-13 |
Not clear |
| G M Zhan. [Left-side endoscopic sinus surgery for Th2 type nasal polyps]. Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery. vol 56. issue 3. 2021-04-08. PMID:33730820. |
[left-side endoscopic sinus surgery for th2 type nasal polyps]. |
2021-04-08 |
2023-08-13 |
Not clear |
| Tim Delemarre, Natalie De Ruyck, Gabriele Holtappels, Claus Bachert, Elien Gevaer. Unravelling the expression of interleukin-9 in chronic rhinosinusitis: A possible role for Staphylococcus aureus. Clinical and translational allergy. vol 10. issue 1. 2020-12-12. PMID:33292477. |
chronic rhinosinusitis with nasal polyps (crswnp) is a th2 biased inflammation, associated with nasal colonization of staphylococcus (s.) aureus. |
2020-12-12 |
2023-08-13 |
Not clear |
| Selene K Bantz, Zhou Zhu, Tao Zhen. The Atopic March: Progression from Atopic Dermatitis to Allergic Rhinitis and Asthma. Journal of clinical & cellular immunology. vol 5. issue 2. 2020-10-01. PMID:25419479. |
this induces systemic th2 immunity that predisposes patients to allergic nasal responses and promotes airway hyper reactivity. |
2020-10-01 |
2023-08-13 |
Not clear |
| Rui Zheng, Dan Wang, Kai Wang, Wen-Xiang Gao, Qin-Tai Yang, Li-Jie Jiang, Min Zhou, Yu-Jie Cao, Jianbo Shi, Yueqi Su. Elevated expression of IL-17RB and ST2 on myeloid dendritic cells is associated with a Th2-skewed eosinophilic inflammation in nasal polyps. Clinical and translational allergy. vol 8. 2020-09-30. PMID:30519393. |
this study aimed to measure the expressions of il-17rb, st2 and tslpr, receptor of il-25, il-33, and tslp respectively, on myeloid dcs in nasal polyps (np) and evaluate their association with local th2 inflammation and disease severity in patients with np. |
2020-09-30 |
2023-08-13 |
Not clear |
| Yi Wei, Renqiang Ma, Jia Zhang, Xingmei Wu, Guodong Yu, Xianting Hu, Jian Li, Zhuofu Liu, Wendong Ji, Huabin Li, Weiping We. Excessive periostin expression and Th2 response in patients with nasal polyps: association with asthma. Journal of thoracic disease. vol 10. issue 12. 2020-09-30. PMID:30746204. |
excessive periostin expression and th2 response in patients with nasal polyps: association with asthma. |
2020-09-30 |
2023-08-13 |
Not clear |
| Tomoe Nishimura, Osamu Kaminuma, Mayumi Saeki, Noriko Kitamura, Akio Mori, Takachika Hiro. Suppressive effect of environmental tobacco smoke on murine Th2 cell-mediated nasal eosinophilic inflammation. Asia Pacific allergy. vol 10. issue 2. 2020-09-28. PMID:32411583. |
suppressive effect of environmental tobacco smoke on murine th2 cell-mediated nasal eosinophilic inflammation. |
2020-09-28 |
2023-08-13 |
Not clear |
| Suoyi Feng, Longzhu Ju, Ziqi Shao, Mark Grzanna, Lu Jia, Ming Li. Therapeutic Effect of C-C Chemokine Receptor Type 1 (CCR1) Antagonist BX471 on Allergic Rhinitis. Journal of inflammation research. vol 13. 2020-09-28. PMID:32801828. |
allergic rhinitis (ar) is an immunoglobulin e (ige)-mediated inflammatory respiratory hypersensitivity characterized by elevated th2 cytokines and infiltration of inflammatory cells to nasal tissues. |
2020-09-28 |
2023-08-13 |
mouse |
| Brandi T Johnson-Weaver, Gregory D Sempowski, Herman F Staat. Nasal peanut+ CpG immunotherapy enhances peanut-specific IFN-γ in Th2 cells and IL-10 in non-Th2 cells in mice. Allergy. vol 74. issue 11. 2020-09-03. PMID:30746720. |
nasal peanut+ cpg immunotherapy enhances peanut-specific ifn-γ in th2 cells and il-10 in non-th2 cells in mice. |
2020-09-03 |
2023-08-13 |
mouse |
| Yun-Xiu Wang, Zhao-Wei Gu, Li-Ying Ha. The environmental hormone nonylphenol interferes with the therapeutic effects of G protein-coupled estrogen receptor specific agonist G-1 on murine allergic rhinitis. International immunopharmacology. vol 78. 2020-07-13. PMID:31835084. |
the expression of transcription factors unique to th1, th2, treg cells and cytokine levels in nasal mucosa were evaluated by real-time pcr and cytometric bead arrays. |
2020-07-13 |
2023-08-13 |
mouse |