| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Giovanni Musso, Roberto Gambino, Franco De Michieli, Marilena Durazzo, Gianfranco Pagano, Maurizio Cassade. Adiponectin gene polymorphisms modulate acute adiponectin response to dietary fat: Possible pathogenetic role in NASH. Hepatology (Baltimore, Md.). vol 47. issue 4. 2008-04-28. PMID:18311774. |
in both patients and controls, these genotypes exhibited a blunted postprandial adiponectin response and higher postprandial triglycerides (tg), free fatty acids (ffa), oxidized ldl (oxldl), and vldl levels than their counterparts, despite comparable fasting adipokines, lipids, dietary habits, adiposity, and insulin resistance. |
2008-04-28 |
2023-08-12 |
Not clear |
| Xing Xian Yu, Sanjay K Pandey, Sheri L Booten, Susan F Murray, Brett P Monia, Sanjay Bhano. Reduced adiposity and improved insulin sensitivity in obese mice with antisense suppression of 4E-BP2 expression. American journal of physiology. Endocrinology and metabolism. vol 294. issue 3. 2008-04-24. PMID:18198353. |
treatment decreased liver triglyceride (tg) content by >50%, normalized plasma glucose and insulin levels, and reduced glucose excursion during glucose tolerance test. |
2008-04-24 |
2023-08-12 |
mouse |
| b' Sibel Tulgar Kinik, Namik Ozbek, Muammer Yuce, Ayse Canan Yazici, Hasibe Verdi, F Belgin Ata\\xc3\\xa. PAI-1 gene 4G/5G polymorphism, cytokine levels and their relations with metabolic parameters in obese children. Thrombosis and haemostasis. vol 99. issue 2. 2008-04-22. PMID:18278185.' |
the mean relative body mass index (bmi) and homa-ir score, vldl, tg, insulin, pai-1, tnfalpha levels were higher, and hdl and tgfbeta levels were lower in the obese group. |
2008-04-22 |
2023-08-12 |
Not clear |
| b' Sibel Tulgar Kinik, Namik Ozbek, Muammer Yuce, Ayse Canan Yazici, Hasibe Verdi, F Belgin Ata\\xc3\\xa. PAI-1 gene 4G/5G polymorphism, cytokine levels and their relations with metabolic parameters in obese children. Thrombosis and haemostasis. vol 99. issue 2. 2008-04-22. PMID:18278185.' |
also, a positive correlation was found between pai-1 and tnfalpha levels, and relative bmi, homa-ir score, insulin, tg, hdl levels. |
2008-04-22 |
2023-08-12 |
Not clear |
| Seungwan Jee, Daeyoun Hwang, Sujin Seo, Yongkyu Kim, Chuelkyu Kim, Byungguk Kim, Sunbo Shim, Suhae Lee, Jisoon Sin, Changjun Bae, Byoungchun Lee, Meekyung Jang, Minsun Kim, Suyoun Yim, Insurk Jang, Jungsik Cho, Kabryong Cha. Microarray analysis of insulin-regulated gene expression in the liver: the use of transgenic mice co-expressing insulin-siRNA and human IDE as an animal model. International journal of molecular medicine. vol 20. issue 6. 2008-04-18. PMID:17982690. |
to characterize the changes in global gene expression in the livers of h1/sirnainsulin-cmv/hide transgenic (tg) mice in response to the reduced bioavailability of insulin, total rna extracted from the livers of 20-week-old tg and non-tg mice was converted to cdna, labeled with biotin and hybridized to oligonucleotide microarrays. |
2008-04-18 |
2023-08-12 |
mouse |
| Seungwan Jee, Daeyoun Hwang, Sujin Seo, Yongkyu Kim, Chuelkyu Kim, Byungguk Kim, Sunbo Shim, Suhae Lee, Jisoon Sin, Changjun Bae, Byoungchun Lee, Meekyung Jang, Minsun Kim, Suyoun Yim, Insurk Jang, Jungsik Cho, Kabryong Cha. Microarray analysis of insulin-regulated gene expression in the liver: the use of transgenic mice co-expressing insulin-siRNA and human IDE as an animal model. International journal of molecular medicine. vol 20. issue 6. 2008-04-18. PMID:17982690. |
two hundred and fifty-one and 73 genes were up- and down-regulated, respectively by insulin in h1/sirnainsulin-cmv/hide tg mice compared to the controls. |
2008-04-18 |
2023-08-12 |
mouse |
| Seungwan Jee, Daeyoun Hwang, Sujin Seo, Yongkyu Kim, Chuelkyu Kim, Byungguk Kim, Sunbo Shim, Suhae Lee, Jisoon Sin, Changjun Bae, Byoungchun Lee, Meekyung Jang, Minsun Kim, Suyoun Yim, Insurk Jang, Jungsik Cho, Kabryong Cha. Microarray analysis of insulin-regulated gene expression in the liver: the use of transgenic mice co-expressing insulin-siRNA and human IDE as an animal model. International journal of molecular medicine. vol 20. issue 6. 2008-04-18. PMID:17982690. |
these results indicate that the microarray analysis identifies several gene functional groups and individual genes that respond to a sustained reduction in the insulin levels in the livers of tg mice. |
2008-04-18 |
2023-08-12 |
mouse |
| Tomohito Gohda, Hiromichi Gotoh, Mitsuo Tanimoto, Michiko Sato, Hiroaki Io, Kayo Kaneko, Chieko Hamada, Yasuhiko Tomin. Relationship between abdominal fat accumulation and insulin resistance in hemodialysis patients. Hypertension research : official journal of the Japanese Society of Hypertension. vol 31. issue 1. 2008-04-15. PMID:18360022. |
furthermore, crp was positively correlated with bmi, vfa, sfa, tg, high-density lipoprotein (hdl)-cholesterol, atherosclerosis index (ai), immunoreactive insulin (iri) and homa-ir in simple regression analysis. |
2008-04-15 |
2023-08-12 |
Not clear |
| Joel B Mitchell, James R Rowe, Meena Shah, James J Barbee, Austen M Watkins, Chad Stephens, Steve Simmon. Effect of prior exercise on postprandial triglycerides in overweight young women after ingesting a high-carbohydrate meal. International journal of sport nutrition and exercise metabolism. vol 18. issue 1. 2008-04-14. PMID:18272933. |
blood was analyzed for triglycerides (tg), blood glucose (bg), and insulin (in). |
2008-04-14 |
2023-08-12 |
human |
| Joji Miyawaki, Setsuya Kamei, Kenshi Sakayama, Haruyasu Yamamoto, Hiroshi Masun. 4-tert-octylphenol regulates the differentiation of C3H10T1/2 cells into osteoblast and adipocyte lineages. Toxicological sciences : an official journal of the Society of Toxicology. vol 102. issue 1. 2008-04-10. PMID:18065773. |
since this treatment strongly induced the expression of peroxisome proliferator-activated receptor r (pparr) but did not stimulate triacylglycerol (tg) accumulation in cells, c3h10t1/2 cells in the control and op-treated cultures were incubated for 2 days with a hormone mixture (insulin [ins], dexamethasone, and 1-methyl-3-isobutylxanthine) and incubated for an additional 5 days with ins alone. |
2008-04-10 |
2023-08-12 |
mouse |
| Guo-Ping Lin, Tao Jiang, Xiao-Bo Hu, Xin-Hui Qiao, Qin-Hui Tu. Effect of Siraitia grosvenorii polysaccharide on glucose and lipid of diabetic rabbits induced by feeding high fat/high sucrose chow. Experimental diabetes research. vol 2007. 2008-03-28. PMID:18273381. |
after administration of sgp for 4 weeks, the fasting blood glucose (fbg), plasma insulin levels (ins), plasma total cholesterol (tc), triglyceride (tg), and hdl-c were assayed. |
2008-03-28 |
2023-08-12 |
Not clear |
| William B Kannel, Ramachandran S Vasan, Michelle J Keyes, Lisa M Sullivan, Sander J Robin. Usefulness of the triglyceride-high-density lipoprotein versus the cholesterol-high-density lipoprotein ratio for predicting insulin resistance and cardiometabolic risk (from the Framingham Offspring Cohort). The American journal of cardiology. vol 101. issue 4. 2008-03-28. PMID:18312765. |
increased triglycerides (tg) and decreased high-density lipoprotein (hdl) cholesterol are key metabolic abnormalities in patients with insulin resistance (ir) states, including diabetes mellitus. |
2008-03-28 |
2023-08-12 |
Not clear |
| Marco Gentile, Salvatore Panico, Fabrizio Jossa, Amalia Mattiello, Stefania Ubaldi, Gennaro Marotta, Paolo Pauciullo, Paolo Rubb. Small dense LDL particles and metabolic syndrome in a sample of middle-aged women. Findings from Progetto Atena. Clinica chimica acta; international journal of clinical chemistry. vol 388. issue 1-2. 2008-03-27. PMID:18035055. |
after controlling for age, insulin and apo b, ms diagnosis (or 4.0; 95% ci 1.76-9.09; p<0.001 for ms diagnosis) and ms components (tg, hdl-c) (or 4.41; 95% ci 1.22-15.87; p=0.023 for ln tg); (or 0.94; 95% ci 0.89-0.98; p=0.009 for hdl-c) remained significantly associated with high ldl score (upper quintile). |
2008-03-27 |
2023-08-12 |
human |
| Akari Inada, Hiroshi Kanamori, Hidenori Arai, Tomoyuki Akashi, Makoto Araki, Gordon C Weir, Atsushi Fukats. A model for diabetic nephropathy: advantages of the inducible cAMP early repressor transgenic mouse over the streptozotocin-induced diabetic mouse. Journal of cellular physiology. vol 215. issue 2. 2008-03-25. PMID:18270980. |
the icer igamma tg mouse is an interesting model of sustained hyperglycemia due to its low production of insulin and insulin-producing beta cells. |
2008-03-25 |
2023-08-12 |
mouse |
| Anne E Sumner, Catherine C Cowi. Ethnic differences in the ability of triglyceride levels to identify insulin resistance. Atherosclerosis. vol 196. issue 2. 2008-03-24. PMID:17254586. |
but as insulin resistant non-hispanic blacks (nhb) often have triglyceride (tg) levels below the thresholds set by these syndromes, the ability of either tg or these syndromes to identify high risk nhb is unknown. |
2008-03-24 |
2023-08-12 |
human |
| Anne E Sumner, Catherine C Cowi. Ethnic differences in the ability of triglyceride levels to identify insulin resistance. Atherosclerosis. vol 196. issue 2. 2008-03-24. PMID:17254586. |
using the national health and nutrition examination survey (nhanes) 1999-2002, our goals were to determine by ethnicity: (1) the prevalence of each of these syndromes; (2) the ability of fasting tg concentrations to identify insulin resistance at cut-off levels established by these syndromes, specifically 130, 150 and 176 mg/dl. |
2008-03-24 |
2023-08-12 |
human |
| S Zhao, Y Chu, C Zhang, Y Lin, K Xu, P Yang, J Fan, E Li. Diet-induced central obesity and insulin resistance in rabbits. Journal of animal physiology and animal nutrition. vol 92. issue 1. 2008-03-17. PMID:18184386. |
plasma levels of triglycerides (tg), total cholesterol (tc), glucose and insulin were measured. |
2008-03-17 |
2023-08-12 |
human |
| S Zhao, Y Chu, C Zhang, Y Lin, K Xu, P Yang, J Fan, E Li. Diet-induced central obesity and insulin resistance in rabbits. Journal of animal physiology and animal nutrition. vol 92. issue 1. 2008-03-17. PMID:18184386. |
although there were no differences in plasma tg, tc, glucose, insulin levels and blood pressure between the two groups, hfsd-fed rabbits showed impaired glucose clearance associated with higher levels of insulin secretion compared to control rabbits. |
2008-03-17 |
2023-08-12 |
human |
| Melanie G Cree, Robert R Wolf. Postburn trauma insulin resistance and fat metabolism. American journal of physiology. Endocrinology and metabolism. vol 294. issue 1. 2008-03-13. PMID:17957035. |
we propose that the insulin resistance is likely related to the development of "ectopic" fat stores, i.e., triglyceride (tg) storage in sites such as the liver and muscle cells. |
2008-03-13 |
2023-08-12 |
Not clear |
| Melanie G Cree, Robert R Wolf. Postburn trauma insulin resistance and fat metabolism. American journal of physiology. Endocrinology and metabolism. vol 294. issue 1. 2008-03-13. PMID:17957035. |
the resultant increases in intracellular tg or related lipid products may in turn contribute to alterations in insulin signaling. |
2008-03-13 |
2023-08-12 |
Not clear |