| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Judy A Butler, Tory M Hagen, Régis Morea. Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and downregulating liver triacylglycerol secretion. Archives of biochemistry and biophysics. vol 485. issue 1. 2009-05-15. PMID:19232511. |
the observation that mice lacking the enzyme sn-glycerol-3-phosphate acyltransferase are protected from insulin resistance suggests the possibility that the regulation of tg synthesis be a target for therapy. |
2009-05-15 |
2023-08-12 |
mouse |
| Matthew J Wat. Storing up trouble: does accumulation of intramyocellular triglyceride protect skeletal muscle from insulin resistance? Clinical and experimental pharmacology & physiology. vol 36. issue 1. 2009-04-30. PMID:18986321. |
increasing tg content by muscle-specific overexpression of diacylglycerol acyltransferase (dgat) 1 protected mice from insulin resistance. |
2009-04-30 |
2023-08-12 |
mouse |
| Matthew J Wat. Storing up trouble: does accumulation of intramyocellular triglyceride protect skeletal muscle from insulin resistance? Clinical and experimental pharmacology & physiology. vol 36. issue 1. 2009-04-30. PMID:18986321. |
conversely, overexpression of dgat2 in glycolytic muscle resulted in accumulation of tg and ceramide and insulin resistance in these tissues. |
2009-04-30 |
2023-08-12 |
mouse |
| D A Tanianskiĭ, E M Firova, L V Shatilina, A D Denisenk. [Adiponectin: lowering in metabolic syndrome and independent relation to hypertriglyceridemia]. Kardiologiia. vol 48. issue 12. 2009-04-28. PMID:19076090. |
body mass index (bmi), waist circumference (wc), index of insulin resistance , levels of glucose, insulin, free fatty acids (ffa), triglycerides (tg) were lower in 3rd tertile of distribution of adiponectin blood content compared with 1st tertile. |
2009-04-28 |
2023-08-12 |
human |
| D A Tanianskiĭ, E M Firova, L V Shatilina, A D Denisenk. [Adiponectin: lowering in metabolic syndrome and independent relation to hypertriglyceridemia]. Kardiologiia. vol 48. issue 12. 2009-04-28. PMID:19076090. |
significant negative correlations were found between adiponectin content and bmi (r=-0.36), wc (r=-0.34), index (r=-0.31), level of diastolic arterial pressure (r=-0.34), concentrations of glucose (r=-0.24), insulin (r=-0.26), ffa (r=-0.24), tg (r=-0.45), uric acid (r=-0.29). |
2009-04-28 |
2023-08-12 |
human |
| Cun-Zhi Han, Li-Li Du, Jie-Xian Jing, Xian-Wen Zhao, Fu-Guo Tian, Jing Shi, Bao-Guo Tian, Xiu-Ying Liu, Li-Jiao Zhan. Associations among lipids, leptin, and leptin receptor gene Gin223Arg polymorphisms and breast cancer in China. Biological trace element research. vol 126. issue 1-3. 2009-04-21. PMID:18668212. |
we found that the serum levels of leptin, insulin, triglyceride (tg), free cholesterol (fch), apolipoprotain (apo) a1, and bmi were significantly higher in breast cancer cases than the controls, while physical activity was clearly less in breast cancer cases (p < 0.02 approximately p < 0.001, respectively). |
2009-04-21 |
2023-08-12 |
Not clear |
| Cun-Zhi Han, Li-Li Du, Jie-Xian Jing, Xian-Wen Zhao, Fu-Guo Tian, Jing Shi, Bao-Guo Tian, Xiu-Ying Liu, Li-Jiao Zhan. Associations among lipids, leptin, and leptin receptor gene Gin223Arg polymorphisms and breast cancer in China. Biological trace element research. vol 126. issue 1-3. 2009-04-21. PMID:18668212. |
interestingly, logistic regression analysis showed that lepr gene gln223arg polymorphism and elevated leptin, insulin, tg, fch, apoa1, whr, and reduced apob increased the risk of developing breast cancer, respectively. |
2009-04-21 |
2023-08-12 |
Not clear |
| Cun-Zhi Han, Li-Li Du, Jie-Xian Jing, Xian-Wen Zhao, Fu-Guo Tian, Jing Shi, Bao-Guo Tian, Xiu-Ying Liu, Li-Jiao Zhan. Associations among lipids, leptin, and leptin receptor gene Gin223Arg polymorphisms and breast cancer in China. Biological trace element research. vol 126. issue 1-3. 2009-04-21. PMID:18668212. |
and, it also suggested that lepr gene gln223arg polymorphisms, elevated leptin, insulin, tg, fch, apoa1, whr, and reduced apob should play a major role in the development of breast cancer. |
2009-04-21 |
2023-08-12 |
Not clear |
| F Lavoie, F Frisch, P Brassard, F Normand-Lauzière, D Cyr, R Gagnon, R Drouin, J-P Baillargeon, A C Carpentie. Relationship between total and high molecular weight adiponectin levels and plasma nonesterified fatty acid tolerance during enhanced intravascular triacylglycerol lipolysis in men. The Journal of clinical endocrinology and metabolism. vol 94. issue 3. 2009-04-07. PMID:19066306. |
increased plasma nonesterified fatty acid (nefa) appearance during enhanced intravascular triacylglycerol (tg) lipolysis is a marker of metabolic adipose tissue dysfunction and may lead to the development of insulin resistance. |
2009-04-07 |
2023-08-12 |
Not clear |
| B Selma Mohammed, Samuel Cohen, Dominic Reeds, V Leroy Young, Samuel Klei. Long-term effects of large-volume liposuction on metabolic risk factors for coronary heart disease. Obesity (Silver Spring, Md.). vol 16. issue 12. 2009-04-03. PMID:18820648. |
metabolic endpoints (oral glucose tolerance, homeostasis model assessment of insulin resistance, blood pressure and plasma triglyceride (tg), high-density lipoprotein (hdl)-cholesterol, and low-density lipoprotein (ldl)-cholesterol concentrations) obtained at 10 through 208 weeks were not different from baseline and did not change over time. |
2009-04-03 |
2023-08-12 |
human |
| J Capea. Insulin resistance and steatosis in humans. Diabetes & metabolism. vol 34. issue 6 Pt 2. 2009-03-24. PMID:19195626. |
strong adverse relationships between adipose tissue, liver and muscles in these patients result in lipotoxicity, with deposition of triglycerides (tg) within the liver and muscles together with insulin resistance. |
2009-03-24 |
2023-08-12 |
human |
| J Capea. Insulin resistance and steatosis in humans. Diabetes & metabolism. vol 34. issue 6 Pt 2. 2009-03-24. PMID:19195626. |
insulin signals in the liver through its tyrosine-kinase receptors to negatively control hepatic glucose production (hgp), replenish glycogen stores and synthesize fatty acids (fa), leading to tg exported as vldl. |
2009-03-24 |
2023-08-12 |
human |
| Guang-Hua Zhai, Ping Wen, Lan-Fang Guo, Lu Che. [Association of apolipoprotein A5 gene -1131T/C polymorphism with lipid metabolism and insulin resistance in patients with type II diabetes mellitus]. Yi chuan = Hereditas. vol 29. issue 5. 2009-03-13. PMID:17548321. |
the -1131c allele contributed to the increase of serum levels of tg, tc and ldl-c and but had no effect on profiles of insulin resistance in dm patients. |
2009-03-13 |
2023-08-12 |
human |
| Takeshi Kanda, Jonathan D Brown, Gabriela Orasanu, Silke Vogel, Frank J Gonzalez, Juliano Sartoretto, Thomas Michel, Jorge Plutzk. PPARgamma in the endothelium regulates metabolic responses to high-fat diet in mice. The Journal of clinical investigation. vol 119. issue 1. 2009-03-10. PMID:19065047. |
when gammaec/bm-ko mice were fed a high-fat diet, they had decreased adiposity and increased insulin sensitivity compared with control mice, despite increased serum ffa and triglyceride (tg) levels. |
2009-03-10 |
2023-08-12 |
mouse |
| Robert K Semple, Alison Sleigh, Peter R Murgatroyd, Claire A Adams, Les Bluck, Sarah Jackson, Alessandra Vottero, Dipak Kanabar, Valentine Charlton-Menys, Paul Durrington, Maria A Soos, T Adrian Carpenter, David J Lomas, Elaine K Cochran, Phillip Gorden, Stephen O'Rahilly, David B Savag. Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis. The Journal of clinical investigation. vol 119. issue 2. 2009-03-10. PMID:19164855. |
here we show that humans with generalized insulin resistance caused by either mutations in the insulin receptor gene or inhibitory antibodies specific for the insulin receptor uniformly exhibited low serum tg and normal hdl cholesterol levels. |
2009-03-10 |
2023-08-12 |
mouse |
| Anne-Louise Ponsonby, Leigh Blizzard, Angela Pezic, Jenny A Cochrane, Justine A Ellis, Ruth Morley, Jo L Dickinson, Michele M Sale, Stephen M Richards, Terence Dwye. Adiposity gain during childhood, ACE I/D polymorphisms and metabolic outcomes. Obesity (Silver Spring, Md.). vol 16. issue 9. 2009-03-05. PMID:18551123. |
we aimed to (i) determine the relative importance of childhood gain in upper body adiposity for insulin resistance (ir) and triglyceridemia (tg); (ii) examine whether the associations between adiposity and metabolic indices were more evident in those with the ace dd genotype. |
2009-03-05 |
2023-08-12 |
Not clear |
| Mi Jung Park, Su Ryun Jung, Hyun Lyung Jung, Bruce W Craig, Chong-Do Lee, Ho Youl Kan. Effects of 4 weeks recombinant human growth hormone administration on insulin resistance of skeletal muscle in rats. Yonsei medical journal. vol 49. issue 6. 2009-03-03. PMID:19108026. |
thus, we investigated the effects of rhgh treatment on muscle triglyceride (tg) and ceramide content, and insulin sensitivity after 4 weeks of rhgh administration in rats. |
2009-03-03 |
2023-08-12 |
human |
| Anne E Sumne. The relationship of body fat to metabolic disease: influence of sex and ethnicity. Gender medicine. vol 5. issue 4. 2009-02-26. PMID:19108808. |
although tg levels are excellent predictors of insulin resistance in whites, they are not effective markers of insulin resistance in blacks. |
2009-02-26 |
2023-08-12 |
Not clear |
| O R Rebolledo, C A Marra, A Raschia, S Rodriguez, J J Gagliardin. Abdominal adipose tissue: early metabolic dysfunction associated to insulin resistance and oxidative stress induced by an unbalanced diet. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 40. issue 11. 2009-02-13. PMID:18622897. |
the glucose (g), triglyceride (tg), and insulin (i) plasma levels, and the activity of antioxidant enzymes, lyposoluble antioxidants, total glutathione (gsh), lipid peroxidation as tbars, fatty acid (fa) composition of aat-tg as well as their release by incubated pieces of aat were measured. |
2009-02-13 |
2023-08-12 |
rat |
| Ali Sazci, Gurler Akpinar, Cem Aygun, Emel Ergul, Omer Senturk, Sadettin Hulag. Association of apolipoprotein E polymorphisms in patients with non-alcoholic steatohepatitis. Digestive diseases and sciences. vol 53. issue 12. 2009-02-03. PMID:18465245. |
body mass index (bmi), waist circumference (wc), ast, alt, fasting blood sugar (fbs), total cholesterol, triglyceride (tg), low-density lipoprotein (ldl) cholesterol, very low-density lipoprotein (vldl) cholesterol, insulin and ferritin levels were significantly higher in the 57 patients with nash compared with the 245 healthy controls. |
2009-02-03 |
2023-08-12 |
human |