| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Arvinder K Dhalla, Mei Yee Wong, Peter J Voshol, Luiz Belardinelli, Gerald M Reave. A1 adenosine receptor partial agonist lowers plasma FFA and improves insulin resistance induced by high-fat diet in rodents. American journal of physiology. Endocrinology and metabolism. vol 292. issue 5. 2007-07-19. PMID:17227958. |
hf diet feeding to rats for 2 wk caused a significant increase in insulin, ffa, and triglyceride (tg) concentrations compared with rats fed chow. |
2007-07-19 |
2023-08-12 |
mouse |
| Arvinder K Dhalla, Mei Yee Wong, Peter J Voshol, Luiz Belardinelli, Gerald M Reave. A1 adenosine receptor partial agonist lowers plasma FFA and improves insulin resistance induced by high-fat diet in rodents. American journal of physiology. Endocrinology and metabolism. vol 292. issue 5. 2007-07-19. PMID:17227958. |
cvt-3619 (1 mg/kg) caused a time-dependent decrease in fasting insulin, ffa, and tg concentrations. |
2007-07-19 |
2023-08-12 |
mouse |
| Arvinder K Dhalla, Mei Yee Wong, Peter J Voshol, Luiz Belardinelli, Gerald M Reave. A1 adenosine receptor partial agonist lowers plasma FFA and improves insulin resistance induced by high-fat diet in rodents. American journal of physiology. Endocrinology and metabolism. vol 292. issue 5. 2007-07-19. PMID:17227958. |
treatment with cvt-3619 for 2 wk resulted in significant lowering of ffa, tg, and insulin concentrations in rats on hf diet. |
2007-07-19 |
2023-08-12 |
mouse |
| Arvinder K Dhalla, Mei Yee Wong, Peter J Voshol, Luiz Belardinelli, Gerald M Reave. A1 adenosine receptor partial agonist lowers plasma FFA and improves insulin resistance induced by high-fat diet in rodents. American journal of physiology. Endocrinology and metabolism. vol 292. issue 5. 2007-07-19. PMID:17227958. |
in conclusion, cvt-3619 treatment lowers ffa and tg concentrations and improves insulin sensitivity in rodent models of insulin resistance. |
2007-07-19 |
2023-08-12 |
mouse |
| Tsutomu Hiran. [Metabolic syndrome and small dense LDL-cholesterol]. Rinsho byori. The Japanese journal of clinical pathology. vol 55. issue 5. 2007-07-13. PMID:17593688. |
it has been proposed that increased triglyceride (tg) production in the liver due to insulin resistance preferentially produces tg-rich very-low density lipoproteins (vldl1), which finally generate sd-ldl particles. |
2007-07-13 |
2023-08-12 |
Not clear |
| Tsutomu Hiran. [Metabolic syndrome and small dense LDL-cholesterol]. Rinsho byori. The Japanese journal of clinical pathology. vol 55. issue 5. 2007-07-13. PMID:17593688. |
sd-ldl-c levels were positively correlated with tg, ldl c, and apolipoprotein b, and were inversely with hdl-c. sd-ldl-c levels were also correlated positively with waist circumference, blood pressure, and insulin resistance index, and negatively with adiponectin level. |
2007-07-13 |
2023-08-12 |
Not clear |
| Norio Tada, Hiroshi Yoshid. [Clinical significance of triglyceride-rich lipoproteins in metabolic syndrome]. Rinsho byori. The Japanese journal of clinical pathology. vol 55. issue 5. 2007-07-13. PMID:17593689. |
increase in triglyceride (tg) -rich lipoproteins is one of the symptoms clustered in metabolic syndrome and is associated with increased plasma free fatty acid level derived from central obesity and insulin resistance. |
2007-07-13 |
2023-08-12 |
Not clear |
| V A Gaysinskaya, O Karatayev, G-Q Chang, S F Leibowit. Increased caloric intake after a high-fat preload: relation to circulating triglycerides and orexigenic peptides. Physiology & behavior. vol 91. issue 1. 2007-07-03. PMID:17383691. |
this overeating after a hf preload was invariably associated with a 2- to 3-fold increase in circulating levels of triglycerides (tg), with no change in leptin or insulin. |
2007-07-03 |
2023-08-12 |
rat |
| Elena Ryder, Eglee Silva, Tulio Sulbarán, Virginia Fernández, Gilberto Campos, Gustavo Calmon, Emilio Clavell, Xiomara Raleigh, Hermes Flore. Black Hispanics have a worse cardiovascular risk profile than mixed Hispanics in Venezuela. Investigacion clinica. vol 48. issue 1. 2007-06-14. PMID:17432543. |
blood pressure (bp), waist circumference, as well as fasting insulin, fasting blood glucose (fbg), triglycerides (tg) and high-density lipoprotein cholesterol (hdl-c) levels were measured. |
2007-06-14 |
2023-08-12 |
human |
| Giuseppe Derosa, Arrigo F G Cicero, Filippo Scalise, Maria A Avanzini, Carmine Tinelli, Mario N Piccinni, Emmanouil Peros, Diego Geroldi, Elena Fogari, Angela D'Angel. Metalloproteinase-2 and -9 in diabetic and nondiabetic subjects during acute coronary syndromes. Endothelium : journal of endothelial cell research. vol 14. issue 1. 2007-06-06. PMID:17364896. |
the following parameters were measured: body mass index (bmi), glycosylated hemoglobin (hba1c), fasting plasma glucose (fpg), fasting plasma insulin (fpi), homeostasis model assessment index (homa index), systolic blood pressure (sbp), diastolic blood pressure (dbp), total cholesterol (tc), low-density lipoprotein cholesterol (ldl-c), high-density lipoprotein cholesterol (hdl-c), triglycerides (tg), lipoprotein(a) [lp(a)], plasminogen activator inhibitor-1 (pai-1), homocysteine (hct), fibrinogen (fg), high-sensitivity c-reactive protein (hs-crp), and plasma levels of mmp-2, mmp-9, timp-1, and timp-2. |
2007-06-06 |
2023-08-12 |
human |
| Ramalingam Saravanan, Leelavinothan Par. Effect of a novel insulinotropic agent, succinic acid monoethyl ester, on lipids and lipoproteins levels in rats with streptozotocin-nicotinamide-induced type 2 diabetes. Journal of biosciences. vol 31. issue 5. 2007-05-29. PMID:17301496. |
at the end of experimental period, the effect of ems on plasma glucose, insulin, thiobarbituric acid reactive substances (tbars) and hydroperoxide (hp) and serum triglycerides (tg), phospholipids (pl), free fatty acids (ffa), total cholesterol (tc), very low density lipoprotein-cholesterol (vldl-c) and low density lipoprotein-cholesterol (ldl-c), high-density lipoprotein-cholesterol (hdl-c) and the percentage of antiatherogenic index (aai) (ratio of hdl-c to total cholesterol) were studied. |
2007-05-29 |
2023-08-12 |
rat |
| Vladimir Savransky, Ashika Nanayakkara, Angelica Vivero, Jianguo Li, Shannon Bevans, Philip L Smith, Michael S Torbenson, Vsevolod Y Polotsk. Chronic intermittent hypoxia predisposes to liver injury. Hepatology (Baltimore, Md.). vol 45. issue 4. 2007-05-29. PMID:17393512. |
cih also induced hyperglycemia, a decrease in fasting serum insulin levels, and mild elevation of fasting serum total cholesterol and triglycerides (tg). |
2007-05-29 |
2023-08-12 |
mouse |
| Roberto Gambino, Maurizio Cassader, Gianfranco Pagano, Marilena Durazzo, Giovanni Muss. Polymorphism in microsomal triglyceride transfer protein: a link between liver disease and atherogenic postprandial lipid profile in NASH? Hepatology (Baltimore, Md.). vol 45. issue 5. 2007-05-25. PMID:17464986. |
the severity of liver histology, the magnitude of triglycerides (tg), free fatty acid (ffa), and ldl-conjugated diene responses, and the fall in hdl-c and apoa1 were significantly higher in nash g/g (66% of patients) than in the other genotypes, despite similar adipokine profile and degree of insulin resistance. |
2007-05-25 |
2023-08-12 |
Not clear |
| Kashif Sheikh, Germán Camejo, Boel Lanne, Torbjörn Halvarsson, Marie Rydén Landergren, Nicholas D Oake. Beyond lipids, pharmacological PPARalpha activation has important effects on amino acid metabolism as studied in the rat. American journal of physiology. Endocrinology and metabolism. vol 292. issue 4. 2007-05-21. PMID:17164430. |
the high-fat diet elevated plasma levels of insulin and triglycerides (tg), and wy 14,643 treatment ameliorated this insulin resistance and dyslipidemia, lowering plasma insulin and tg levels. |
2007-05-21 |
2023-08-12 |
rat |
| Riad A Bayoumi, Saeed A S Al-Yahyaee, Sulayma A Albarwani, Syed G Rizvi, Saleh Al-Hadabi, Firial F Al-Ubaidi, Ali T Al-Hinai, Mohammed N Al-Kindi, Haleema T Adnan, Hameeda S Al-Barwany, Antony G Comuzzie, Guowen Cai, Juan C Lopez-Alvarenga, Mohammed O Hassa. Heritability of determinants of the metabolic syndrome among healthy Arabs of the Oman family study. Obesity (Silver Spring, Md.). vol 15. issue 3. 2007-05-15. PMID:17372303. |
highly significant, but widely spread, h2 values were obtained for: height (0.68), weight (0.68), bmi (0.68), serum hdl (0.63), serum leptin (0.55), percentage body fat (0.53), total serum cholesterol (0.53), fasting serum insulin (0.51), homeostasis model assessment-insulin resistance index (0.48), serum tg (0.43), waist circumference (0.40), diastolic blood pressure (0.38), and 2-hour glucose level (0.17), whereas for the metabolic syndrome itself, h2 was 0.38. |
2007-05-15 |
2023-08-12 |
Not clear |
| Riad A Bayoumi, Saeed A S Al-Yahyaee, Sulayma A Albarwani, Syed G Rizvi, Saleh Al-Hadabi, Firial F Al-Ubaidi, Ali T Al-Hinai, Mohammed N Al-Kindi, Haleema T Adnan, Hameeda S Al-Barwany, Antony G Comuzzie, Guowen Cai, Juan C Lopez-Alvarenga, Mohammed O Hassa. Heritability of determinants of the metabolic syndrome among healthy Arabs of the Oman family study. Obesity (Silver Spring, Md.). vol 15. issue 3. 2007-05-15. PMID:17372303. |
other determinants such as insulin resistance, abdominal obesity, diastolic blood pressure, and tg levels seem to be more environmentally driven. |
2007-05-15 |
2023-08-12 |
Not clear |
| John Q Zhang, Lisa L Ji, Vicki S Fretwell, Guadalupe Nune. Effect of exercise on postprandial lipemia in men with hypertriglyceridemia. European journal of applied physiology. vol 98. issue 6. 2007-05-14. PMID:17006711. |
subjects were 10 hypertriglyceridemia (htg) males with insulin resistance [age = 40.1 +/- 2.2 years, body weight = 96.3 +/- 3.3 kg, fasting triglyceride (tg) = 263 +/- 25 mg/dl, vo(2)max = 37 +/- 1.1 ml/kg/min, and homeostatic model assessment (homa-ir, an index of insulin resistance) = 3.05 +/- 0.40]. |
2007-05-14 |
2023-08-12 |
human |
| Isabelle B Bauche, Samira Ait El Mkadem, Anne-Marie Pottier, Maximin Senou, Marie-Christine Many, René Rezsohazy, Luc Penicaud, Norikazu Maeda, Tohru Funahashi, Sonia M Brichar. Overexpression of adiponectin targeted to adipose tissue in transgenic mice: impaired adipocyte differentiation. Endocrinology. vol 148. issue 4. 2007-04-24. PMID:17204560. |
adipose mass remodeling favors enhanced insulin sensitivity and improved lipid profile of tg mice. |
2007-04-24 |
2023-08-12 |
mouse |
| Junji Kobayashi, Atsushi Nohara, Masa-aki Kawashiri, Akihiro Inazu, Junji Koizumi, Katsuyuki Nakajima, Hiroshi Mabuch. Serum lipoprotein lipase mass: clinical significance of its measurement. Clinica chimica acta; international journal of clinical chemistry. vol 378. issue 1-2. 2007-04-17. PMID:17223095. |
studies have shown that pre-heparin plasma or serum lpl mass has significant relationships with serum lipids and lipoproteins, visceral fat area, insulin resistance, and even the development of coronary atherosclerosis in cross-sectional studies, although this might be a metabolic surrogate marker with almost no catalytic activities, which does not appear to be involved in catalyzing hydrolysis of tg in tg-rich lipoproteins. |
2007-04-17 |
2023-08-12 |
human |
| Giuseppe Derosa, Arrigo F G Cicero, Angela D'Angelo, Pietro D Ragonesi, Leonardina Ciccarelli, Mario N Piccinni, Fabio Pricolo, Sibilla A T Salvadeo, Ilaria Ferrari, Alessia Gravina, Roberto Fogar. Telmisartan and irbesartan therapy in type 2 diabetic patients treated with rosiglitazone: effects on insulin-resistance, leptin and tumor necrosis factor-alpha. Hypertension research : official journal of the Japanese Society of Hypertension. vol 29. issue 11. 2007-04-12. PMID:17345784. |
we evaluated body mass index (bmi), glycemic control (hba1c fasting plasma glucose and insulin levels [fpg, and fpi, respectively], and homeostasis model assessment [homa] index), lipid profile (total cholesterol [tc], low density lipoprotein-cholesterol [ldl-c], high density lipoprotein-cholesterol [hdl-c], and triglycerides [tg]), systolic and diastolic blood pressure (sbp and dbp), tumor necrosis factor-alpha (tnf-alpha), and leptin during the 12 months of this treatment. |
2007-04-12 |
2023-08-12 |
human |