| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Dégano, E Peiró, P Miralles, R A Silvestre, J Marc. Effects of rat pancreatic polypeptide on islet-cell secretion in the perfused rat pancreas. Metabolism: clinical and experimental. vol 41. issue 3. 1992-04-03. PMID:1347399. |
however, during aminogenic priming of the d cell, the inhibition of insulin output induced by rpp was accompanied by an increase in somatostatin release. |
1992-04-03 |
2023-08-11 |
human |
| H C Fehmann, R Göke, B Göke, R Eissele, R Arnol. Helodermin and islet hormone release in isolated rat pancreas. International journal of pancreatology : official journal of the International Association of Pancreatology. vol 8. issue 4. 1992-04-01. PMID:1686442. |
the effect of helodermin (1,10,100 pmol/l), a new member of the vip/secretin/glucagon peptide family, was investigated in glucose- (10 mmol/l) and arginine- (10 mmol/l) induced insulin, glucagon, and somatostatin secretion from the isolated perfused rat pancreas. |
1992-04-01 |
2023-08-11 |
rat |
| K M Nelson, C L Long, R Bailey, R J Smith, H L Laws, W S Blakemor. Regulation of glucose kinetics in trauma patients by insulin and glucagon. Metabolism: clinical and experimental. vol 41. issue 1. 1992-03-27. PMID:1347143. |
the current study was undertaken to evaluate the contribution of insulin and glucagon to regulation of glucose metabolism in man following severe, traumatic injury by manipulating concentrations of insulin and glucagon with infusions of somatostatin. |
1992-03-27 |
2023-08-11 |
human |
| K M Nelson, C L Long, R Bailey, R J Smith, H L Laws, W S Blakemor. Regulation of glucose kinetics in trauma patients by insulin and glucagon. Metabolism: clinical and experimental. vol 41. issue 1. 1992-03-27. PMID:1347143. |
modulation of insulin and glucagon with somatostatin indicated that non-insulin-mediated glucose uptake (nimgu) was significantly elevated in injured patients (12.2 +/- 0.94 mumol/kg/min v 7.4 +/- 0.61 mumol/kg/min). |
1992-03-27 |
2023-08-11 |
human |
| T Iu Koval', D Kh Khamidov, L E Andreeva, K G Gazaria. [Influence of the expression of the human growth hormone releasing factor gene on hormone levels in a transgenic rabbit]. Problemy endokrinologii. vol 37. issue 6. 1992-03-26. PMID:1788215. |
analysis of the hormonal status of the transgene animal has shown change in the levels of the majority of hormones: a 6-10-fold increase in insulin; a 2-3-fold increase in the level of triiodothyronine, thyroxin; a reduced somatostatin concentration, a two-fold decrease in the level of progesterone, and a four-fold decrease in the level of testosterone. |
1992-03-26 |
2023-08-11 |
mouse |
| N Altszuler, B Winkler, C R Rosenberg, F X Pi-Sunyer, A R Fuch. Role of insulin and glucagon in oxytocin effects on glucose metabolism. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 199. issue 2. 1992-03-24. PMID:1346936. |
the studies were carried out in normal, unanesthetized dogs in which ot infusion was superimposed on infusion of either somatostatin, which suppresses insulin and glucagon secretion, or clonidine, which suppresses insulin secretion only. |
1992-03-24 |
2023-08-11 |
Not clear |
| N Altszuler, B Winkler, C R Rosenberg, F X Pi-Sunyer, A R Fuch. Role of insulin and glucagon in oxytocin effects on glucose metabolism. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 199. issue 2. 1992-03-24. PMID:1346936. |
infusion of 0.2 microgram/kg/min of somatostatin suppressed basal levels of plasma insulin and glucagon and inhibited the ot-induced rise of these hormones by about 60-80% of that seen with ot alone. |
1992-03-24 |
2023-08-11 |
Not clear |
| K C McHardy, M A McNurlan, E Milne, A G Calder, L M Fearns, J Broom, P J Garlic. The effect of insulin suppression on postprandial nutrient metabolism: studies with infusion of somatostatin and insulin. European journal of clinical nutrition. vol 45. issue 11. 1992-03-13. PMID:1685991. |
the effect of insulin suppression on postprandial nutrient metabolism: studies with infusion of somatostatin and insulin. |
1992-03-13 |
2023-08-11 |
human |
| K C McHardy, M A McNurlan, E Milne, A G Calder, L M Fearns, J Broom, P J Garlic. The effect of insulin suppression on postprandial nutrient metabolism: studies with infusion of somatostatin and insulin. European journal of clinical nutrition. vol 45. issue 11. 1992-03-13. PMID:1685991. |
the role of insulin was investigated by repeating a control study with the addition of an infusion of somatostatin, a hormone which can suppress insulin release. |
1992-03-13 |
2023-08-11 |
human |
| C G Ostenson, B Ahrén, O Johansson, S Karlsson, M Hilliges, S Efendi. Diazepam binding inhibitor and the endocrine pancreas. Neuropharmacology. vol 30. issue 12B. 1992-03-10. PMID:1780037. |
its major hormonal regulators include insulin, glucagon and somatostatin from the endocrine pancreas. |
1992-03-10 |
2023-08-11 |
rat |
| C G Ostenson, B Ahrén, O Johansson, S Karlsson, M Hilliges, S Efendi. Diazepam binding inhibitor and the endocrine pancreas. Neuropharmacology. vol 30. issue 12B. 1992-03-10. PMID:1780037. |
thus, it is likely that peptides, released from cells of the gut or endocrine pancreas or from peptidergic nerves, affect glucose homeostasis by modulating the secretion of insulin, glucagon and somatostatin. |
1992-03-10 |
2023-08-11 |
rat |
| E Adeghate, T Donát. Morphometric and immunohistochemical study on the endocrine cells of pancreatic transplants. Experimental and clinical endocrinology. vol 98. issue 3. 1992-03-06. PMID:1685711. |
four types of endocrine cells were identified and their distribution was as follows: insulin: 42-52%, glucagon: 11-28%, somatostatin: 4%, and pancreatic polypeptide-positive cells: 3-6%. |
1992-03-06 |
2023-08-11 |
rat |
| W Knepel, M Vallejo, J A Chafitz, J F Habene. The pancreatic islet-specific glucagon G3 transcription factors recognize control elements in the rat somatostatin and insulin-I genes. Molecular endocrinology (Baltimore, Md.). vol 5. issue 10. 1992-03-05. PMID:1685554. |
it has been shown previously that g3-binding and transactivating proteins are present in islet cell lines expressing the glucagon, somatostatin, and insulin genes, but not in several nonislet cell lines. |
1992-03-05 |
2023-08-11 |
rat |
| W Knepel, M Vallejo, J A Chafitz, J F Habene. The pancreatic islet-specific glucagon G3 transcription factors recognize control elements in the rat somatostatin and insulin-I genes. Molecular endocrinology (Baltimore, Md.). vol 5. issue 10. 1992-03-05. PMID:1685554. |
in addition, when fused to glucagon or somatostatin minimal promoters in reporter plasmids, these enhancer elements of the three islet hormone-producing genes functionally activate transcription when transfected into islet cell lines producing glucagon, insulin, or somatostatin. |
1992-03-05 |
2023-08-11 |
rat |
| M Sasaki, T Arai, T Usui, Y Ok. Immunohistochemical, ultrastructural, and hormonal studies on the endocrine pancreas of voles (Microtus arvalis) with monosodium aspartate-induced diabetes. Veterinary pathology. vol 28. issue 6. 1992-02-27. PMID:1685274. |
blood glucose concentration and tissue content of insulin, glucagon, and somatostatin were also measured. |
1992-02-27 |
2023-08-11 |
Not clear |
| D Malm, B Vonen, P G Burhol, J Florholme. The interaction between cAMP-dependent and cAMP-independent mechanisms in mediating the somatostatin inhibition of insulin secretion in isolated rat pancreatic islets. Acta physiologica Scandinavica. vol 143. issue 3. 1992-02-27. PMID:1685288. |
the interaction between camp-dependent and camp-independent mechanisms in mediating the somatostatin inhibition of insulin secretion in isolated rat pancreatic islets. |
1992-02-27 |
2023-08-11 |
rat |
| D Malm, B Vonen, P G Burhol, J Florholme. The interaction between cAMP-dependent and cAMP-independent mechanisms in mediating the somatostatin inhibition of insulin secretion in isolated rat pancreatic islets. Acta physiologica Scandinavica. vol 143. issue 3. 1992-02-27. PMID:1685288. |
to characterize the intracellular mechanisms by which somatostatin modulates the insulin secretion, studies were performed with isolated rat pancreatic islets at 12 mmol l-1 glucose. |
1992-02-27 |
2023-08-11 |
rat |
| D Malm, B Vonen, P G Burhol, J Florholme. The interaction between cAMP-dependent and cAMP-independent mechanisms in mediating the somatostatin inhibition of insulin secretion in isolated rat pancreatic islets. Acta physiologica Scandinavica. vol 143. issue 3. 1992-02-27. PMID:1685288. |
an additional inhibition of the insulin secretion was observed when somatostatin was combined with verapamil in the absence, but not in the presence of dibutyryl-camp. |
1992-02-27 |
2023-08-11 |
rat |
| D Malm, B Vonen, P G Burhol, J Florholme. The interaction between cAMP-dependent and cAMP-independent mechanisms in mediating the somatostatin inhibition of insulin secretion in isolated rat pancreatic islets. Acta physiologica Scandinavica. vol 143. issue 3. 1992-02-27. PMID:1685288. |
we conclude that somatostatin inhibits the glucose-induced insulin secretion both by camp-dependent mechanism which requires extracellular ca2+, and by camp-independent/verapamil-sensitive ca(2+)-channel-dependent mechanism. |
1992-02-27 |
2023-08-11 |
rat |
| B Algers, A Madej, S Rojanasthien, K Uvnäs-Mober. Quantitative relationships between suckling-induced teat stimulation and the release of prolactin, gastrin, somatostatin, insulin, glucagon and vasoactive intestinal polypeptide in sows. Veterinary research communications. vol 15. issue 5. 1992-02-24. PMID:1685275. |
quantitative relationships between suckling-induced teat stimulation and the release of prolactin, gastrin, somatostatin, insulin, glucagon and vasoactive intestinal polypeptide in sows. |
1992-02-24 |
2023-08-11 |
Not clear |