Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
P Leduque, R Scharfmann, J A Chayvialle, S Aratan-Spire, A Basmaciogullari, P Czernichow, P M Duboi. Insulin, glucagon and somatostatin in fetal rat islets maintained free-floating in culture: immunocytochemistry and radioimmunoassay. Biology of the cell. vol 74. issue 2. 1992-07-08. PMID:1350743. |
insulin, glucagon, and somatostatin contents were determined in extracts of the cultured tissue. |
1992-07-08 |
2023-08-11 |
rat |
J Rouru, R Huupponen, U Pesonen, M Koul. Subchronic treatment with metformin produces anorectic effect and reduces hyperinsulinemia in genetically obese Zucker rats. Life sciences. vol 50. issue 23. 1992-07-08. PMID:1350851. |
metformin did not change plasma corticosterone levels or insulin and somatostatin concentrations in the pancreas. |
1992-07-08 |
2023-08-11 |
rat |
C A Conover, P D Lee, J A Kanaley, J T Clarkson, M D Jense. Insulin regulation of insulin-like growth factor binding protein-1 in obese and nonobese humans. The Journal of clinical endocrinology and metabolism. vol 74. issue 6. 1992-06-29. PMID:1375600. |
to assess the dynamics of insulin regulated igfbp-1, 10 obese and 8 nonobese women were studied during sequential saline infusion (0-90 min), hyperinsulinemia (insulin infusion; 90-210 min) and hypoinsulinemia (somatostatin + gh infusion; 210-330 min). |
1992-06-29 |
2023-08-11 |
human |
Y Kunoh, A Iguchi, K Uemura, H Miura, T Tamagawa, T Mano, K Nonogaki, M Gotoh, N Sakamot. Effects of adrenergic blockers on central nervous system-mediated hyperglycemia in fed rats. Metabolism: clinical and experimental. vol 41. issue 5. 1992-06-19. PMID:1350317. |
neostigmine was injected into the third cerebral ventricle of bilaterally adrenodemedullectomized (admx) rats, while somatostatin and insulin were administered intravenously. |
1992-06-19 |
2023-08-11 |
rat |
B Vonen, J Florholmen, D Malm, P Torjessen, P G Burho. Glucagon mediates arginine-induced somatostatin secretion from isolated rat pancreatic islets. Scandinavian journal of clinical and laboratory investigation. vol 52. issue 2. 1992-06-19. PMID:1350374. |
glucagon has been suggested to be a mediator of intra-islet paracrine effect of insulin and somatostatin during nutritive stimulation. |
1992-06-19 |
2023-08-11 |
rat |
B Vonen, J Florholmen, D Malm, P Torjessen, P G Burho. Glucagon mediates arginine-induced somatostatin secretion from isolated rat pancreatic islets. Scandinavian journal of clinical and laboratory investigation. vol 52. issue 2. 1992-06-19. PMID:1350374. |
the aim of this study was to reveal possible intra-islet interactions between insulin, somatostatin and glucagon in a batch stimulation model with isolated pancreatic islets. |
1992-06-19 |
2023-08-11 |
rat |
B Vonen, J Florholmen, D Malm, P Torjessen, P G Burho. Glucagon mediates arginine-induced somatostatin secretion from isolated rat pancreatic islets. Scandinavian journal of clinical and laboratory investigation. vol 52. issue 2. 1992-06-19. PMID:1350374. |
in our hands arginine stimulated somatostatin secretion only in the presence of insulin antiserum. |
1992-06-19 |
2023-08-11 |
rat |
B Vonen, J Florholmen, D Malm, P Torjessen, P G Burho. Glucagon mediates arginine-induced somatostatin secretion from isolated rat pancreatic islets. Scandinavian journal of clinical and laboratory investigation. vol 52. issue 2. 1992-06-19. PMID:1350374. |
the addition of glucagon antiserum inhibited these effects of insulin antiserum on somatostatin secretion. |
1992-06-19 |
2023-08-11 |
rat |
P Joanny, G Peyre, J Steinberg, V Guillaume, G Pesce, D Becquet, C Olive. Effect of diabetes on in vivo and in vitro hypothalamic somatostatin release. Neuroendocrinology. vol 55. issue 5. 1992-06-18. PMID:1350065. |
chronic insulin replacement therapy in diabetic animals partly normalized somatostatin levels as well as plasma gh and glucose levels. |
1992-06-18 |
2023-08-11 |
rat |
J Permert, M Mogaki, A Andrén-Sandberg, K Kazakoff, P M Pou. Pancreatic mixed ductal-islet tumors. Is this an entity? International journal of pancreatology : official journal of the International Association of Pancreatology. vol 11. issue 1. 1992-06-12. PMID:1316418. |
thirty-eight human pancreatic cancer specimens were studied for the reactivity of cancer cells with monoclonal antibodies against insulin, glucagon, somatostatin, pancreatic polypeptide (pp), vasoactive intestinal peptide (vip), gastrin, calcitonin, and with argyrophilic reactivity. |
1992-06-12 |
2023-08-11 |
human |
W J Rossowski, S Zacharia, Z Mungan, V Ozmen, A Ertan, L M Baylor, N Y Jiang, D H Co. Reduced gastric acid inhibitory effect of a pGIP(1-30)NH2 fragment with potent pancreatic amylase inhibitory activity. Regulatory peptides. vol 39. issue 1. 1992-06-10. PMID:1374565. |
gastric inhibitory polypeptide (gip) strongly stimulates insulin secretion in the presence of glucose and also stimulates somatostatin release from gastric mucosa. |
1992-06-10 |
2023-08-11 |
rat |
W J Rossowski, S Zacharia, Z Mungan, V Ozmen, A Ertan, L M Baylor, N Y Jiang, D H Co. Reduced gastric acid inhibitory effect of a pGIP(1-30)NH2 fragment with potent pancreatic amylase inhibitory activity. Regulatory peptides. vol 39. issue 1. 1992-06-10. PMID:1374565. |
since insulin and somatostatin are involved in regulation of exocrine pancreatic and gastric secretion in rats, we compared the inhibitory effects of pgip and the pgip(1-30)nh2 fragment on pancreatic amylase and gastric acid secretion. |
1992-06-10 |
2023-08-11 |
rat |
P L Herrera, J Huarte, F Sanvito, P Meda, L Orci, J D Vassall. Embryogenesis of the murine endocrine pancreas; early expression of pancreatic polypeptide gene. Development (Cambridge, England). vol 113. issue 4. 1992-06-05. PMID:1811941. |
in both dorsal and ventral buds, the majority of these endocrine cells contain pp, but many also contain glucagon, insulin or somatostatin. |
1992-06-05 |
2023-08-11 |
mouse |
Y Ceti. Chromogranin A immunoreactivity and Grimelius' argyrophilia. A correlative study in mammalian endocrine cells. Anatomy and embryology. vol 185. issue 3. 1992-05-29. PMID:1349463. |
we found that endocrine cells could be positive for chromogranin a and argyrophilia (e.g., aminergic endocrine cells); or positive for chromogranin a but negative for argyrophilia (e.g., insulin cells of all species; somatostatin cells of cattle and pig); or negative for chromogranin a but positive for argyrophilia (e.g., glucagon cells of pig and guinea pig); or negative for chromogranin a and argyrophilia (e.g., somatostatin cells of man and guinea pig). |
1992-05-29 |
2023-08-11 |
cattle |
S Attvall, J Fowelin, H von Schenck, U Smith, I Lage. Insulin-antagonistic effects of pulsatile and continuous glucagon infusions in man--a comparison with the effect of adrenaline. The Journal of clinical endocrinology and metabolism. vol 74. issue 5. 1992-05-26. PMID:1569157. |
glucose production and utilization were evaluated with d-3-3h-glucose and somatostatin was used in all studies to inhibit the endogenous release of insulin and glucagon. |
1992-05-26 |
2023-08-11 |
human |
D C Bradley, R N Bergma. Restoration of stable metabolic conditions during islet suppression in dogs. The American journal of physiology. vol 262. issue 4 Pt 1. 1992-05-21. PMID:1348903. |
somatostatin was infused peripherally at 0.8 microgram.min-1.kg-1, insulin was infused intraportally at 200 microu.min-1.kg-1, and glucagon was infused intraportally at 0, 0.6, 1, 2, 5, or 20 ng.min-1.kg-1 in conscious overnight-fasted dogs. |
1992-05-21 |
2023-08-11 |
Not clear |
K K Ho, A B Jenkins, S M Furler, M Borkman, D J Chishol. Impact of octreotide, a long-acting somatostatin analogue, on glucose tolerance and insulin sensitivity in acromegaly. Clinical endocrinology. vol 36. issue 3. 1992-05-21. PMID:1563080. |
impact of octreotide, a long-acting somatostatin analogue, on glucose tolerance and insulin sensitivity in acromegaly. |
1992-05-21 |
2023-08-11 |
Not clear |
K K Ho, A B Jenkins, S M Furler, M Borkman, D J Chishol. Impact of octreotide, a long-acting somatostatin analogue, on glucose tolerance and insulin sensitivity in acromegaly. Clinical endocrinology. vol 36. issue 3. 1992-05-21. PMID:1563080. |
we aimed to investigate the impact of a long-acting somatostatin analogue, octreotide, on glucose tolerance and on insulin sensitivity in acromegaly. |
1992-05-21 |
2023-08-11 |
Not clear |
D C Bradley, R N Bergma. Hepatic glucagon sensitivity and fasting glucose concentration in normal dogs. The American journal of physiology. vol 262. issue 4 Pt 1. 1992-05-21. PMID:1566839. |
somatostatin was infused to inhibit endogenous insulin and glucagon, insulin was replaced intraportally at 200 microu.min-1.kg-1, and glucagon was infused intraportally at 0, 0.6, 1, 2, 5, or 20 ng.min-1.kg-1. |
1992-05-21 |
2023-08-11 |
Not clear |
A Iguchi, Y Kunoh, M Gotoh, H Miura, K Uemura, T Tamagawa, N Sakamot. Relative contribution of nervous system and hormones to CNS-mediated hyperglycemia is determined by the neurochemical specificity in the brain. Physiology & behavior. vol 50. issue 5. 1992-05-07. PMID:1805263. |
group 2 comprised intact rats receiving the constant infusion of a) somatostatin to inhibit the endogenous secretion of insulin and glucagon, and b) insulin to maintain the plasma insulin concentration at basal levels. |
1992-05-07 |
2023-08-11 |
rat |