| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Inoue, A Hisatomi, F Umeda, H Nawat. Effects of exogenous somatostatin and insulin on islet amyloid polypeptide (amylin) release from perfused rat pancreas. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 24. issue 6. 1992-08-27. PMID:1353050. |
effects of exogenous somatostatin and insulin on islet amyloid polypeptide (amylin) release from perfused rat pancreas. |
1992-08-27 |
2023-08-11 |
rat |
| K Inoue, A Hisatomi, F Umeda, H Nawat. Effects of exogenous somatostatin and insulin on islet amyloid polypeptide (amylin) release from perfused rat pancreas. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 24. issue 6. 1992-08-27. PMID:1353050. |
this study examined the effects of exogenous somatostatin and insulin on the release of islet amyloid polypeptide (iapp), or amylin, from the isolated perfused rat pancreas. |
1992-08-27 |
2023-08-11 |
rat |
| K Inoue, A Hisatomi, F Umeda, H Nawat. Effects of exogenous somatostatin and insulin on islet amyloid polypeptide (amylin) release from perfused rat pancreas. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 24. issue 6. 1992-08-27. PMID:1353050. |
somatostatin inhibited the release of both amylin and insulin from the perfused pancreas to the same extent. |
1992-08-27 |
2023-08-11 |
rat |
| K Inoue, A Hisatomi, F Umeda, H Nawat. Effects of exogenous somatostatin and insulin on islet amyloid polypeptide (amylin) release from perfused rat pancreas. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 24. issue 6. 1992-08-27. PMID:1353050. |
the infusion of 10 nm somatostatin resulted in 40% inhibition of the secretion of both amylin and insulin induced by 11.1 mm glucose and 10 mm arginine, and this inhibition was significantly increased to 70% by the infusion of 100 nm somatostatin (p less than 0.05). |
1992-08-27 |
2023-08-11 |
rat |
| K Inoue, A Hisatomi, F Umeda, H Nawat. Effects of exogenous somatostatin and insulin on islet amyloid polypeptide (amylin) release from perfused rat pancreas. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 24. issue 6. 1992-08-27. PMID:1353050. |
these findings suggest that the release of amylin may be negatively regulated by somatostatin and that circulating insulin may have no direct effect on the release of amylin at least at a physiological concentration. |
1992-08-27 |
2023-08-11 |
rat |
| P Petit, M M Loubatières-Marian. Potassium channels of the insulin-secreting B cell. Fundamental & clinical pharmacology. vol 6. issue 3. 1992-08-20. PMID:1628875. |
thus, galanine, somatostatin and adrenaline, which inhibit insulin release, increase k+ conductance by a g protein-dependent mechanism; both peptides were reported to open atp-sensitive k+ channels in insulin-secreting cell line rinm5f. |
1992-08-20 |
2023-08-11 |
Not clear |
| N Edwin, J Yamada, C M Leig. A light-microscopic immunocytochemical study of the endocrine pancreas in the Australian fat-tailed dunnart (Sminthopsis crassicaudata). Singapore medical journal. vol 33. issue 3. 1992-08-14. PMID:1352914. |
serial paraffin sections were stained individually with primary antibodies for anti-porcine glucagon, anti-beef pork insulin, anti-human somatostatin, and anti-avian pancreatic polypeptide (app), anti-bovine pancreatic polypeptide (bpp), anti-serotonin, anti-porcine motilin, showing the same islet. |
1992-08-14 |
2023-08-11 |
human |
| N Edwin, J Yamada, C M Leig. A light-microscopic immunocytochemical study of the endocrine pancreas in the Australian fat-tailed dunnart (Sminthopsis crassicaudata). Singapore medical journal. vol 33. issue 3. 1992-08-14. PMID:1352914. |
cells immunoreactive to porcine glucagon, porcine insulin, human somatostatin, app, bpp were found in endocrine islets, but bpp and app also appear to be scattered amidst the exocrine portion. |
1992-08-14 |
2023-08-11 |
human |
| M Vallejo, C P Miller, J F Habene. Somatostatin gene transcription regulated by a bipartite pancreatic islet D-cell-specific enhancer coupled synergetically to a cAMP response element. The Journal of biological chemistry. vol 267. issue 18. 1992-08-06. PMID:1352291. |
relative to the early expression of the glucagon and insulin genes on embryonic days 10 and 12, respectively, the expression of the somatostatin gene is delayed (day 17). |
1992-08-06 |
2023-08-11 |
Not clear |
| M Vallejo, L Penchuk, J F Habene. Somatostatin gene upstream enhancer element activated by a protein complex consisting of CREB, Isl-1-like, and alpha-CBF-like transcription factors. The Journal of biological chemistry. vol 267. issue 18. 1992-08-06. PMID:1352292. |
the expression of the genes encoding the hormones glucagon, insulin, somatostatin, and pancreatic polypeptide in the endocrine islets of the pancreas is regulated in a cell-specific manner, defining four distinct cellular phenotypes (a-, b-, d-, and f-cells, respectively). |
1992-08-06 |
2023-08-11 |
human |
| S Dawiskiba, P M Pour, U Stenram, F Sundler, A Andrén-Sandber. Immunohistochemical characterization of endocrine cells in experimental exocrine pancreatic cancer in the Syrian golden hamster. International journal of pancreatology : official journal of the International Association of Pancreatology. vol 11. issue 2. 1992-07-21. PMID:1351511. |
insulin and antinse-reactive cells were the most common, followed in decreasing frequency by glucagon, somatostatin, and pp cells. |
1992-07-21 |
2023-08-11 |
Not clear |
| H Yamagiwa, N Onishi, M Nishi. Heterotopic pancreas of the stomach. Histogenesis and immunohistochemistry. Acta pathologica japonica. vol 42. issue 4. 1992-07-20. PMID:1376953. |
positive cells were found not infrequently in the acini of type-ii cases after staining for pancreatic polypeptide, insulin, glucagon, somatostatin, serotonin, and gastrin. |
1992-07-20 |
2023-08-11 |
Not clear |
| A Iguchi, K Uemura, H Miura, T Ishiguro, K Nonogaki, T Tamagawa, K Goshima, N Sakamot. Mechanism of intrahippocampal neostigmine-induced hyperglycemia in fed rats. Neuroendocrinology. vol 55. issue 1. 1992-07-20. PMID:1608508. |
to evaluate the relative contribution of these glucoregulatory hormones and the nervous system to the net hyperglycemic response, we unilaterally injected neostigmine (5 x 10(-8) mol) into the dorsal hippocampus in the following groups of rats: intact rats with bilateral adrenalectomy to eliminate the action of epinephrine, and rats receiving a constant infusion of somatostatin and insulin to prevent the glucagon response and to maintain the basal insulin level. |
1992-07-20 |
2023-08-11 |
rat |
| A Iguchi, K Uemura, H Miura, T Ishiguro, K Nonogaki, T Tamagawa, K Goshima, N Sakamot. Mechanism of intrahippocampal neostigmine-induced hyperglycemia in fed rats. Neuroendocrinology. vol 55. issue 1. 1992-07-20. PMID:1608508. |
the areas under the glucose curve for rats receiving somatostatin and insulin, adrenalectomy rats, and adrenalectomy rats receiving somatostatin and insulin were, respectively, 82, 31, and 61% of that for intact rats. |
1992-07-20 |
2023-08-11 |
rat |
| S Reddy, N J Bibby, R B Elliot. An immunocytochemical study of endocrine cell development in the early fetal guinea pig pancreas. General and comparative endocrinology. vol 86. issue 2. 1992-07-10. PMID:1351015. |
the presence of insulin, glucagon, pancreatic polypeptide, and somatostatin containing cells and their ontogenic changes were investigated immunocytochemically in the early fetal pancreas of the guinea pig (days 25-40). |
1992-07-10 |
2023-08-11 |
Not clear |
| S Reddy, N J Bibby, R B Elliot. An immunocytochemical study of endocrine cell development in the early fetal guinea pig pancreas. General and comparative endocrinology. vol 86. issue 2. 1992-07-10. PMID:1351015. |
insulin and somatostatin immunoreactive cells were less numerous. |
1992-07-10 |
2023-08-11 |
Not clear |
| S Reddy, N J Bibby, R B Elliot. An immunocytochemical study of endocrine cell development in the early fetal guinea pig pancreas. General and comparative endocrinology. vol 86. issue 2. 1992-07-10. PMID:1351015. |
at these later stages insulin and somatostatin cells were increasingly frequent. |
1992-07-10 |
2023-08-11 |
Not clear |
| S Reddy, N J Bibby, R B Elliot. An immunocytochemical study of endocrine cell development in the early fetal guinea pig pancreas. General and comparative endocrinology. vol 86. issue 2. 1992-07-10. PMID:1351015. |
a small proportion of endocrine cells coexpress either insulin and glucagon or pancreatic polypeptide and somatostatin. |
1992-07-10 |
2023-08-11 |
Not clear |
| K A Heald, C A Hail, R P Hurst, N Kane, R Downin. Separation of beta-cells from dispersed porcine pancreas by selective lectin binding. Diabetes research (Edinburgh, Scotland). vol 17. issue 1. 1992-07-09. PMID:1816975. |
immunohistochemical analysis of the fluorescent populations showed that 93% +/- 2% of these cells contained insulin: none of the cells stained positive for glucagon or somatostatin. |
1992-07-09 |
2023-08-11 |
Not clear |
| P Leduque, R Scharfmann, J A Chayvialle, S Aratan-Spire, A Basmaciogullari, P Czernichow, P M Duboi. Insulin, glucagon and somatostatin in fetal rat islets maintained free-floating in culture: immunocytochemistry and radioimmunoassay. Biology of the cell. vol 74. issue 2. 1992-07-08. PMID:1350743. |
insulin, glucagon and somatostatin in fetal rat islets maintained free-floating in culture: immunocytochemistry and radioimmunoassay. |
1992-07-08 |
2023-08-11 |
rat |