| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Ahrén, M Pettersson, K Uvnäs-Moberg, M Gutniak, S Efendi. Effects of cholecystokinin (CCK)-8, CCK-33, and gastric inhibitory polypeptide (GIP) on basal and meal-stimulated pancreatic hormone secretion in man. Diabetes research and clinical practice. vol 13. issue 3. 1992-01-03. PMID:1683622. |
cck-8, cck-33, and gip were all found to increase the basal plasma levels of insulin, somatostatin, and pp; the increases were observed already in samples taken at 2 min after the injection. |
1992-01-03 |
2023-08-11 |
human |
| B Ahrén, M Pettersson, K Uvnäs-Moberg, M Gutniak, S Efendi. Effects of cholecystokinin (CCK)-8, CCK-33, and gastric inhibitory polypeptide (GIP) on basal and meal-stimulated pancreatic hormone secretion in man. Diabetes research and clinical practice. vol 13. issue 3. 1992-01-03. PMID:1683622. |
cck-8 and gip together (100 pmol/kg for both) increased plasma levels of insulin, pp and somatostatin as much as each of the peptides given alone, both under basal conditions and after the meal intake. |
1992-01-03 |
2023-08-11 |
human |
| K Ono, J Yamada, V D Pai, N Kitamura, E A Gregório, T Yamashita, V J Campo. An ultrastructural study on the endocrine pancreas of Caiman latirostris, with special reference to pancreatic motilin cells. Archives of histology and cytology. vol 54. issue 3. 1991-12-31. PMID:1683242. |
three types of endocrine cells were identified as either glucagon, insulin or somatostatin cells by the presence of such characteristic granules well established in mammals. |
1991-12-31 |
2023-08-11 |
Not clear |
| K Ono, J Yamada, V D Pai, N Kitamura, E A Gregório, T Yamashita, V J Campo. An ultrastructural study on the endocrine pancreas of Caiman latirostris, with special reference to pancreatic motilin cells. Archives of histology and cytology. vol 54. issue 3. 1991-12-31. PMID:1683242. |
immunocytochemical observations confirmed the ultrastructural classification of glucagon, insulin and somatostatin cells. |
1991-12-31 |
2023-08-11 |
Not clear |
| P Diem, R P Robertso. Preventive effects of octreotide (SMS 201-995) on diabetic ketogenesis during insulin withdrawal. British journal of clinical pharmacology. vol 32. issue 5. 1991-12-30. PMID:1954071. |
we conclude that, despite accelerated lipolysis and provision of substrate for ketogenesis during insulin withdrawal, this somatostatin analogue significantly reduces ketogenesis resulting from insulin deprivation, probably secondary to decreasing glucagon secretion. |
1991-12-30 |
2023-08-11 |
Not clear |
| R L Sorenson, D G Garry, T C Brelj. Structural and functional considerations of GABA in islets of Langerhans. Beta-cells and nerves. Diabetes. vol 40. issue 11. 1991-12-19. PMID:1936599. |
effects of gaba on insulin, glucagon, and somatostatin secretion have been proposed. |
1991-12-19 |
2023-08-11 |
Not clear |
| M Beylot, S Picard, C Chambrier, H Vidal, M Laville, R Cohen, A Cotisson, R Morne. Effect of physiological concentrations of insulin and glucagon on the relationship between nonesterified fatty acids availability and ketone body production in humans. Metabolism: clinical and experimental. vol 40. issue 11. 1991-12-12. PMID:1943742. |
to determine the effect of insulin and glucagon on the transformation of nonesterified fatty acids (nefa) into ketone bodies (kb), we measured simultaneously in normal subjects nefa and kb kinetics at different nefa levels in the presence of basal (control test) or increasing insulin concentrations with glucagopenia (somatostatin + insulin infusion, insulin test) and without glucagopenia (somatostatin + insulin + glucagon infusion, glucagon test). |
1991-12-12 |
2023-08-11 |
human |
| M Bendayan, I S Par. Presence of extrapancreatic islets of Langerhans in the duodenal wall of the rat. Diabetologia. vol 34. issue 8. 1991-12-10. PMID:1682201. |
the insulin cells formed the core of the islets while the glucagon, the somatostatin and the pancreatic polypeptide cells were located at the periphery. |
1991-12-10 |
2023-08-11 |
rat |
| C Orskov, S S Poulse. Glucagonlike peptide-I-(7-36)-amide receptors only in islets of Langerhans. Autoradiographic survey of extracerebral tissues in rats. Diabetes. vol 40. issue 10. 1991-12-06. PMID:1657666. |
we also found binding of 125i-glp-i to insulin-, glucagon-, and somatostatin-immunoreactive cells by combined autoradiographic and immunohistochemical analysis of pancreatic specimens using antisera against insulin, glucagon, and somatostatin. |
1991-12-06 |
2023-08-11 |
rat |
| M Hayakawa, K Yokono, M Nagata, N Hatamori, W Ogawa, A Miki, H Mizoguti, S Bab. Morphological analysis of selective destruction of pancreatic beta-cells by cytotoxic T lymphocytes in NOD mice. Diabetes. vol 40. issue 9. 1991-12-06. PMID:1682198. |
in addition, the concentration of pancreatic hormones in the culture medium, used as a marker of cytolysis, also demonstrated that insulin was significantly increased after 6 h of culture, whereas glucagon and somatostatin were not. |
1991-12-06 |
2023-08-11 |
mouse |
| G D Divertie, M D Jensen, J M Mile. Stimulation of lipolysis in humans by physiological hypercortisolemia. Diabetes. vol 40. issue 10. 1991-12-06. PMID:1936585. |
on both occasions, a pancreatic clamp (0.12 micrograms.kg-1.min-1 somatostatin, 0.05 mu.kg-1.min-1 insulin, and 3 ng.kg-1.min-1 growth hormone) was used to maintain plasma hormone concentrations at desired levels. |
1991-12-06 |
2023-08-11 |
human |
| H J Zhang, J B Redmon, J M Andresen, R P Robertso. Somatostatin and epinephrine decrease insulin messenger ribonucleic acid in HIT cells through a pertussis toxin-sensitive mechanism. Endocrinology. vol 129. issue 5. 1991-12-02. PMID:1682135. |
somatostatin and epinephrine decrease insulin messenger ribonucleic acid in hit cells through a pertussis toxin-sensitive mechanism. |
1991-12-02 |
2023-08-11 |
Not clear |
| H J Zhang, J B Redmon, J M Andresen, R P Robertso. Somatostatin and epinephrine decrease insulin messenger ribonucleic acid in HIT cells through a pertussis toxin-sensitive mechanism. Endocrinology. vol 129. issue 5. 1991-12-02. PMID:1682135. |
the sites of action for somatostatin and epinephrine to inhibit insulin secretion have been reported to be exclusively in the exocytotic pathway. |
1991-12-02 |
2023-08-11 |
Not clear |
| H J Zhang, J B Redmon, J M Andresen, R P Robertso. Somatostatin and epinephrine decrease insulin messenger ribonucleic acid in HIT cells through a pertussis toxin-sensitive mechanism. Endocrinology. vol 129. issue 5. 1991-12-02. PMID:1682135. |
we observed that both somatostatin and epinephrine not only inhibit insulin secretion (53 +/- 2% and 50 +/- 2% of control, respectively) but also decrease insulin mrna levels (54 +/- 5% and 66 +/- 5% of control, respectively) and insulin content in hit cells (61 +/- 2% and 51 +/- 1% of control, respectively). |
1991-12-02 |
2023-08-11 |
Not clear |
| H J Zhang, J B Redmon, J M Andresen, R P Robertso. Somatostatin and epinephrine decrease insulin messenger ribonucleic acid in HIT cells through a pertussis toxin-sensitive mechanism. Endocrinology. vol 129. issue 5. 1991-12-02. PMID:1682135. |
these new observations suggest that somatostatin and epinephrine negatively modulate insulin availability through a guanine nucleotide binding protein-mediated step in insulin synthesis before the exocytotic pathway. |
1991-12-02 |
2023-08-11 |
Not clear |
| P Gilon, G Bertrand, M M Loubatières-Mariani, C Remacle, J C Henqui. The influence of gamma-aminobutyric acid on hormone release by the mouse and rat endocrine pancreas. Endocrinology. vol 129. issue 5. 1991-12-02. PMID:1682137. |
exogenous gaba, baclofen (agonist of gabab receptors), muscimol (agonist of gabaa receptors), or bicuculline (antagonist of gabaa receptors) did not affect insulin and somatostatin release by isolated mouse or rat islets. |
1991-12-02 |
2023-08-11 |
mouse |
| P Gilon, G Bertrand, M M Loubatières-Mariani, C Remacle, J C Henqui. The influence of gamma-aminobutyric acid on hormone release by the mouse and rat endocrine pancreas. Endocrinology. vol 129. issue 5. 1991-12-02. PMID:1682137. |
in conclusion, gaba does not affect insulin and somatostatin secretion, but inhibits a-cells, probably by acting on gabaa receptors. |
1991-12-02 |
2023-08-11 |
mouse |
| D Grube, A Jörn. The endocrine pancreas of glucagon-and somatostatin-immunized rabbits. I. Light microscopy and immunohistochemistry. Cell and tissue research. vol 265. issue 2. 1991-11-25. PMID:1682051. |
the latter changes differed after either immunization: glucagon immunization resulted in hypertrophy and hyperplasia of glucagon cells and a decrease in their hormonal content; somatostatin immunization led to an increased proportion of somatostatin cells and a lowered hormonal content of insulin cells. |
1991-11-25 |
2023-08-11 |
rabbit |
| b' M Zamaklar, N Ribarac-Stepi\\xc4\\x87, N Lali\\xc4\\x87, M Devecerski, S Damjanovi\\xc4\\x87, P Djordjevi\\xc4\\x8. [The effect of somatostatin on specific binding of insulin to receptors in patients with non-insulin dependent diabetes]. Glas. Srpska akademija nauka i umetnosti. Odeljenje medicinskih nauka. issue 41. 1991-11-20. PMID:1680775.' |
[the effect of somatostatin on specific binding of insulin to receptors in patients with non-insulin dependent diabetes]. |
1991-11-20 |
2023-08-11 |
human |
| H Yamagiwa, T Onishi, M Nishi. [Histological study of heterotopic pancreas tissue of the stomach--histogenesis and immunohistochemical findings]. Rinsho byori. The Japanese journal of clinical pathology. vol 39. issue 8. 1991-11-18. PMID:1920887. |
staining behavior by insulin, gastrin, glucagon, somatostatin and serotonin was similar to that of normal pancreas. |
1991-11-18 |
2023-08-11 |
Not clear |