| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Melpomeni Moustaki, Stavroula A Paschou, Paraskevi Xekouki, Kalliopi Kotsa, Melpomeni Peppa, Theodora Psaltopoulou, Sophia Kalantaridou, Andromachi Vryonido. Secondary diabetes mellitus in acromegaly. Endocrine. 2023-03-07. PMID:36882643. |
somatostatin analogues inhibit insulin secretion; especially pasireotide (pasi) impairs glycaemic profile in up to 75% of cases, establishing a separate pathophysiologic entity, pasi-induced dm. |
2023-03-07 |
2023-08-14 |
Not clear |
| MingXu Lin, YuHua Chen, Jie Nin. Insulin Autoimmune Syndrome: A Systematic Review. International journal of endocrinology. vol 2023. 2023-02-27. PMID:36844104. |
for patients with severe symptoms, available treatments may include drugs that reduce pancreatic insulin secretion (such as somatostatin and diazoxide), immunosuppressants (glucocorticoids, zaprin, and rituximab), and even plasma exchange to remove autoantibodies from the body. |
2023-02-27 |
2023-08-14 |
Not clear |
| Yumiko Okano Tamura, Jun Sugama, Shin-Ichi Abe, Yuji Shimizu, Hideki Hirose, Masanori Watanab. Selective somatostatin receptor 5 inhibition improves hepatic insulin sensitivity. Pharmacology research & perspectives. vol 11. issue 1. 2022-12-31. PMID:36585794. |
selective somatostatin receptor 5 inhibition improves hepatic insulin sensitivity. |
2022-12-31 |
2023-08-14 |
mouse |
| Sipin Zhu, Xiaoyong Hu, Samuel Bennett, Oscar Charlesworth, Shengnan Qin, Yuliang Mai, Haicheng Dou, Jiake X. Galanin family peptides: Molecular structure, expression and roles in the neuroendocrine axis and in the spinal cord. Frontiers in endocrinology. vol 13. 2022-12-23. PMID:36561569. |
galanin is a neurohormone as well as a neurotransmitter and plays versatile physiological roles for the neuroendocrine axis, such as regulating food intake, insulin level and somatostatin release. |
2022-12-23 |
2023-08-14 |
human |
| Mirjam E van Albada, Klaus Mohnike, Mark J Dunne, Indi Banerjee, Stephen F Bet. Somatostatin receptors in congenital hyperinsulinism: Biology to bedside. Frontiers in endocrinology. vol 13. 2022-10-14. PMID:36237195. |
under healthy conditions, somatostatin secreted from pancreatic islet δ-cells reduces insulin release through somatostatin receptor induced camp-mediated downregulation and paracrine inhibition of β- cells. |
2022-10-14 |
2023-08-14 |
Not clear |
| Hirohumi Suzuki, Toshiharu Yamamot. CXCL14-like immunoreactivity in somatostatin-producing cells of the Japanese quail (Coturnix japonica) pancreas. Anatomia, histologia, embryologia. 2022-09-23. PMID:36148519. |
cxcl14-immunoreactive cells were immuno-positive for somatostatin, but not glucagon and insulin. |
2022-09-23 |
2023-08-14 |
human |
| Hirohumi Suzuki, Toshiharu Yamamot. CXCL14-like immunoreactivity in somatostatin-producing cells of the Japanese quail (Coturnix japonica) pancreas. Anatomia, histologia, embryologia. 2022-09-23. PMID:36148519. |
cxcl14 secreted from somatostatin-producing cells might participate in insulin secretion modulation together with somatostatin. |
2022-09-23 |
2023-08-14 |
human |
| Ananyaa Sridhar, Dawood Khan, Mahmoud Abdelaal, Jessie A Elliott, Violetta Naughton, Peter R Flatt, Carel W Le Roux, Neil G Docherty, Charlotte R Moffet. Differential effects of RYGB surgery and best medical treatment for obesity-diabetes on intestinal and islet adaptations in obese-diabetic ZDSD rats. PloS one. vol 17. issue 9. 2022-09-22. PMID:36137097. |
insulin, glucagon, somatostatin, pyy, glp-1 and gip expression patterns were assessed using immunocytochemistry and analyzed using imagej. |
2022-09-22 |
2023-08-14 |
rat |
| Ahmad A Saied, Monica N Shroyer, Joshua M Taylor, Cecily C Midkif. Functional Insulinomas in a Rhesus Macaque (Macaca mulatta). Journal of comparative pathology. vol 198. 2022-09-18. PMID:36116886. |
histologically, neoplastic cells exhibited neuroendocrine packeting, resembled pancreatic islet cells and immunolabelled for chromogranin a, synaptophysin and insulin but not for somatostatin, gastrin or pancreatic polypeptide. |
2022-09-18 |
2023-08-14 |
monkey |
| Akiko Yuno, Akemi Ikota, Shigeki Koizumi, Yasuo Mashio, Hiroko Imaizumi, Yutaka Sawamura, Akira Shimats. Advanced proliferative diabetic retinopathy and macular edema in acromegaly: a case report and literature review. Diabetology international. vol 13. issue 3. 2022-06-13. PMID:35693995. |
she was given an injection of a long-acting somatostatin analog (octreotide lar) and began taking three bolus mealtime insulin shots with basal insulin beginning 1 month before undergoing a trans-sphenoidal adenomectomy. |
2022-06-13 |
2023-08-14 |
Not clear |
| Ya-Qin Du, Xue-Ying Sha, Jie Cheng, Jin Wang, Jing-Yu Lin, Wen-Tao An, Wei Pan, Li-Jun Zhang, Xiao-Na Tao, YunFei Xu, Ying-Li Jia, Zhao Yang, Peng Xiao, Ming Liu, Jin-Peng Sun, Xiao Y. Endogenous Lipid-GPR120 Signaling Modulates Pancreatic Islet Homeostasis to Different Extents. Diabetes. 2022-04-26. PMID:35472681. |
these two lcfas promoted insulin secretion by inhibiting somatostatin secretion, and showed bias activation of gpr120 in a model system. |
2022-04-26 |
2023-08-13 |
mouse |
| Taylor Simone Morriseau, Christine Doucette, Vernon W Dolinsk. More than meets the islet: Aligning nutrient and paracrine inputs with hormone secretion in health and disease. American journal of physiology. Endocrinology and metabolism. 2022-04-04. PMID:35373587. |
although the mechanisms governing glucose-coupled insulin secretion have received the most attention, there is emerging evidence for a multitude of physiological signalling pathways and paracrine networks that collectively regulate insulin, glucagon, and somatostatin release. |
2022-04-04 |
2023-08-13 |
Not clear |
| Hasan Husni, Sara A Khan, Buraq Alghaieb, Mohammed S Abusamaan, Thomas W Donner, Amir H Hamrahia. Pasireotide use for the treatment of endogenous hyperinsulinemic hypoglycemia refractory to conventional medical therapy: A case report and review of the literature. Clinical case reports. vol 10. issue 3. 2022-03-31. PMID:35356161. |
it has up to 40 times higher affinity for somatostatin receptor subtype 5 in comparison with octreotide, leading to a higher inhibition of insulin release from beta cells. |
2022-03-31 |
2023-08-13 |
Not clear |
| Dawood Khan, R Charlotte Moffett, Peter R Flatt, Andrei I Taraso. Classical and non-classical islet peptides in the control of β-cell function. Peptides. 2021-12-27. PMID:34958851. |
classical islet hormones, insulin, glucagon, pancreatic polypeptide and somatostatin, interact in an autocrine and paracrine manner, to fine-tube the islet function and insulin secretion to the needs of the body. |
2021-12-27 |
2023-08-13 |
Not clear |
| Daniel B Andersen, Jens J Hols. Peptides in the regulation of glucagon secretion. Peptides. vol 148. 2021-12-02. PMID:34748791. |
glucose homeostasis is maintained by the glucoregulatory hormones, glucagon, insulin and somatostatin, secreted from the islets of langerhans. |
2021-12-02 |
2023-08-13 |
Not clear |
| Daniel B Andersen, Jens J Hols. Peptides in the regulation of glucagon secretion. Peptides. vol 148. 2021-12-02. PMID:34748791. |
hormones that may regulate glucagon secretion include locally produced insulin and somatostatin, but also urocortin-3, amylin and pancreatic polypeptide, and from outside the pancreas glucagon-like peptide-1 and 2, peptide tyrosine tyrosine and oxyntomodulin, glucose-dependent insulinotropic polypeptide, neurotensin and ghrelin, as well as the hypothalamic hormones arginine-vasopressin and oxytocin, and calcitonin from the thyroid. |
2021-12-02 |
2023-08-13 |
Not clear |
| J Pires, R L Greathouse, N Quach, M O Huising, K R Crakes, M Miller, C Gilo. The effect of the ghrelin-receptor agonist capromorelin on glucose metabolism in healthy cats. Domestic animal endocrinology. vol 74. 2021-11-30. PMID:32619812. |
somatostatin secretion from islet delta cells is important in maintaining low glycemic variability (gv) by providing negative feedback to beta cells and inhibiting insulin secretion. |
2021-11-30 |
2023-08-13 |
Not clear |
| Jing-Yu Lin, Jie Cheng, Ya-Qin Du, Wei Pan, Zhong Zhang, Jin Wang, Jie An, Fan Yang, Yun-Fei Xu, Hui Lin, Wen-Tao An, Jia Wang, Zhao Yang, Ren-Jie Chai, Xue-Ying Sha, Hui-Li Hu, Jin-Peng Sun, Xiao Y. In vitro expansion of pancreatic islet clusters facilitated by hormones and chemicals. Cell discovery. vol 6. 2021-11-26. PMID:32284878. |
the expanded islet clusters expressed insulin, glucagon and somatostatin, which are markers corresponding to pancreatic β cells, α cells and δ cells, respectively. |
2021-11-26 |
2023-08-13 |
mouse |
| Christopher Gribben, Christopher Lambert, Hendrik A Messal, Ella-Louise Hubber, Chloe Rackham, Ian Evans, Harry Heimberg, Peter Jones, Rocio Sancho, Axel Behren. Ductal Ngn3-expressing progenitors contribute to adult β cell neogenesis in the pancreas. Cell stem cell. vol 28. issue 11. 2021-11-15. PMID:34478642. |
lineage tracing using the neurogenin3 (ngn3)-creert line identified ductal cells expressing the endocrine master transcription factor ngn3 that were positive for the δ cell marker somatostatin and occasionally co-expressed insulin. |
2021-11-15 |
2023-08-13 |
Not clear |
| Mei Wang, Shaoqi Xu, Ya Li, Ni Tang, Hu Chen, Shupeng Zhang, Yanling Liu, Jun Wang, Defang Chen, Xin Zhang, Zhiqiong L. Identification, tissue distribution, and anorexigenic effect of amylin in Siberian sturgeon (Acipenser baeri). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 263. 2021-11-11. PMID:34534676. |
these results show that amylin inhibits feeding in siberian sturgeon by down-regulating the appetite-stimulating factor npy and up-regulating the appetite-suppressing factors somatostatin, mc4r, cck, and insulin. |
2021-11-11 |
2023-08-13 |
Not clear |