| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Ishida, S Röjdmark, G Bloom, M C Chou, J B Fiel. The effect of somatostatin on the hepatic extraction of insulin and glucagon in the anesthetized dog. Endocrinology. vol 106. issue 1. 1980-02-26. PMID:7349954. |
during the final 20 min of the combined infusion of somatostatin, insulin, and glucagon, hepatic extraction of insulin returned to control values and glucagon extraction rose from 7 +/- 12% to 35 +/- 11%. |
1980-02-26 |
2023-08-12 |
dog |
| T Ishida, S Röjdmark, G Bloom, M C Chou, J B Fiel. The effect of somatostatin on the hepatic extraction of insulin and glucagon in the anesthetized dog. Endocrinology. vol 106. issue 1. 1980-02-26. PMID:7349954. |
these results demonstrate that somatostatin may influence peripheral insulin and glucagon values by modifying their hepatic extraction and inhibiting their pancreatic secretion. |
1980-02-26 |
2023-08-12 |
dog |
| H F Kitson, R B McCrossin, M Jimenez, A Middleton, M Silin. Somatostatin treatment of insulin excess due to beta-cell adenoma in a neonate. The Journal of pediatrics. vol 96. issue 1. 1980-02-26. PMID:7350297. |
somatostatin treatment of insulin excess due to beta-cell adenoma in a neonate. |
1980-02-26 |
2023-08-12 |
Not clear |
| D Baetens, F Malaisse-Lagae, A Perrelet, L Orc. Endocrine pancreas: three-dimensional reconstruction shows two types of islets of langerhans. Science (New York, N.Y.). vol 206. issue 4424. 1980-02-15. PMID:390711. |
three-dimensional reconstructions of islets of langerhans, based on immunofluorescent staining of successive serial sections with antiserums to insulin, glucagon, somatostatin, and pancreatic polypeptide reveal a marked difference in the number of cells containing glucagon and pancreatic polypeptide depending on the anatomical location of the islet in the pancreas. |
1980-02-15 |
2023-08-11 |
Not clear |
| J A Lupiáñez, K N Dileepan, S R Wagl. Interrelationship of somatostatin, insulin, and calcium in the control of gluconeogenesis in kidney cortex slices. Biochemical and biophysical research communications. vol 90. issue 4. 1980-02-15. PMID:518589. |
interrelationship of somatostatin, insulin, and calcium in the control of gluconeogenesis in kidney cortex slices. |
1980-02-15 |
2023-08-11 |
Not clear |
| A A Galoia. [Chemistry and biology of hypothalamic cardioactive proteins and peptides]. Voprosy biokhimii mozga. vol 13. 1980-01-24. PMID:228493. |
it enhances the secretion of insulin and counteracts the inhibitory action of somatostatin on the insular apparatus. |
1980-01-24 |
2023-08-11 |
cattle |
| J Dolais-Kitabgi, Y Le Marchand-Brustel, P Freyche. Somatostatin in the pancreas and hypothalamus of obese mice. Diabetologia. vol 17. issue 4. 1980-01-24. PMID:387502. |
the pancreatic content of somatostatin, insulin, and glucagon and the hypothalamic content of somatostatin were examined in ob/ob mice at various ages and in goldthioglucose-obese mice. |
1980-01-24 |
2023-08-11 |
mouse |
| J Dolais-Kitabgi, Y Le Marchand-Brustel, P Freyche. Somatostatin in the pancreas and hypothalamus of obese mice. Diabetologia. vol 17. issue 4. 1980-01-24. PMID:387502. |
in goldthioglucose-obese mice the pancreatic content of insulin was also increased but to a lesser extent than in ob/ob mice; the pancreatic levels of somatostatin and glucagon were unaltered. |
1980-01-24 |
2023-08-11 |
mouse |
| W Waldhäusl, P Bratusch-Marrain, P Nowotn. Increase by somatostatin of the arginine induced rise in blood glucose in untreated insulin requiring diabetics. Endokrinologie. vol 73. issue 3. 1980-01-24. PMID:499100. |
increase by somatostatin of the arginine induced rise in blood glucose in untreated insulin requiring diabetics. |
1980-01-24 |
2023-08-11 |
human |
| W Waldhäusl, P Bratusch-Marrain, P Nowotn. Increase by somatostatin of the arginine induced rise in blood glucose in untreated insulin requiring diabetics. Endokrinologie. vol 73. issue 3. 1980-01-24. PMID:499100. |
these findings indicate a diabetogenic action of somatostatin also in insulin requiring diabetics as long as some residual capacity for insulin release is retained. |
1980-01-24 |
2023-08-11 |
human |
| G J Taborsky, P H Smith, J B Halter, D Port. Glucose infusion potentiates the acute insulin response to nonglucose stimuli during the infusion of somatostatin. Endocrinology. vol 105. issue 5. 1979-12-29. PMID:488008. |
glucose infusion potentiates the acute insulin response to nonglucose stimuli during the infusion of somatostatin. |
1979-12-29 |
2023-08-11 |
Not clear |
| M Nagulesparan, P J Savage, R H Unger, P H Bennet. A simplified method using somatostatin to assess in vivo insulin resistance over a range of obesity. Diabetes. vol 28. issue 11. 1979-12-29. PMID:488547. |
a simplified method using somatostatin to assess in vivo insulin resistance over a range of obesity. |
1979-12-29 |
2023-08-11 |
human |
| W L Mille. Use of recombinant DNA technology for the production of polypeptides. Advances in experimental medicine and biology. vol 118. 1979-12-20. PMID:91311. |
several eucaryotic proteins, including insulin, growth hormone, ovalbumin, dihydrofolate reductase and somatostatin have been produced in bacteria. |
1979-12-20 |
2023-08-11 |
Not clear |
| E Ipp, R H Unge. Bombesin stimulates the release of insulin and glucagon, but not pancreatic somatostatin, from the isolated perfused dog pancreas. Endocrine research communications. vol 6. issue 1. 1979-12-20. PMID:385299. |
bombesin stimulates the release of insulin and glucagon, but not pancreatic somatostatin, from the isolated perfused dog pancreas. |
1979-12-20 |
2023-08-11 |
dog |
| J Järhult, B Ahrén, I Lundquis. Inhibitory effect of somatostatin on insulin secretion during alpha-adrenergic blockade in three different species. Acta endocrinologica. vol 92. issue 1. 1979-12-20. PMID:386685. |
inhibitory effect of somatostatin on insulin secretion during alpha-adrenergic blockade in three different species. |
1979-12-20 |
2023-08-11 |
mouse |
| J Järhult, B Ahrén, I Lundquis. Inhibitory effect of somatostatin on insulin secretion during alpha-adrenergic blockade in three different species. Acta endocrinologica. vol 92. issue 1. 1979-12-20. PMID:386685. |
it has recently been suggested from experiments in dogs that somatostatin suppresses insulin release via a stimulation of the inhibitory alpha-adrenoceptors of the pancreatic b-cell. |
1979-12-20 |
2023-08-11 |
mouse |
| J Järhult, B Ahrén, I Lundquis. Inhibitory effect of somatostatin on insulin secretion during alpha-adrenergic blockade in three different species. Acta endocrinologica. vol 92. issue 1. 1979-12-20. PMID:386685. |
the effect of somatostatin on insulin secretion during alpha-adrenergic blockade with phentolamine was therefore studied in three different species; the rat, the cat and the mouse. |
1979-12-20 |
2023-08-11 |
mouse |
| J Järhult, B Ahrén, I Lundquis. Inhibitory effect of somatostatin on insulin secretion during alpha-adrenergic blockade in three different species. Acta endocrinologica. vol 92. issue 1. 1979-12-20. PMID:386685. |
it was found that somatostatin significantly depressed insulin release during alpha-adrenoceptor blockade in all three species. |
1979-12-20 |
2023-08-11 |
mouse |
| J Järhult, B Ahrén, I Lundquis. Inhibitory effect of somatostatin on insulin secretion during alpha-adrenergic blockade in three different species. Acta endocrinologica. vol 92. issue 1. 1979-12-20. PMID:386685. |
in the rat, infusion of somatostatin at a dose of 0.3 microgram/kg/min decreased basal plasma insulin concentration by 92%. |
1979-12-20 |
2023-08-11 |
mouse |
| J Järhult, B Ahrén, I Lundquis. Inhibitory effect of somatostatin on insulin secretion during alpha-adrenergic blockade in three different species. Acta endocrinologica. vol 92. issue 1. 1979-12-20. PMID:386685. |
in the presence of phentolamine, the same dose of somatostatin lowered plasma insulin by 85%. |
1979-12-20 |
2023-08-11 |
mouse |