| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Efendić, F Enzmann, A Nylén, K Uvnäs-Wallensten, R Luf. Effect of glucose/sulfonylurea interaction on release of insulin, glucagon, and somatostatin from isolated perfused rat pancreas. Proceedings of the National Academy of Sciences of the United States of America. vol 76. issue 11. 1980-03-17. PMID:118458. |
the effect of a sulfonylurea, glibenclamide, on the release of insulin, glucagon, and somatostatin was studied in the isolated perfused rat pancreas. |
1980-03-17 |
2023-08-11 |
rat |
| S Efendić, F Enzmann, A Nylén, K Uvnäs-Wallensten, R Luf. Effect of glucose/sulfonylurea interaction on release of insulin, glucagon, and somatostatin from isolated perfused rat pancreas. Proceedings of the National Academy of Sciences of the United States of America. vol 76. issue 11. 1980-03-17. PMID:118458. |
a moderate glucose load (6.7 mm) inhibited glibenclamide-induced release of somatostatin, whereas the two in combination exerted an additive action on insulin release. |
1980-03-17 |
2023-08-11 |
rat |
| S Efendić, F Enzmann, A Nylén, K Uvnäs-Wallensten, R Luf. Effect of glucose/sulfonylurea interaction on release of insulin, glucagon, and somatostatin from isolated perfused rat pancreas. Proceedings of the National Academy of Sciences of the United States of America. vol 76. issue 11. 1980-03-17. PMID:118458. |
we suggest a paracrine (local) interaction of somatostatin with the alpha and beta cells, which has an important role in the kinetics of insulin and glucagon release induced by sulfonylureas. |
1980-03-17 |
2023-08-11 |
rat |
| G Berger, L Frappar. [Practical immunocytochemistry of the endocrine pancreas]. Annales d'anatomie pathologique. vol 24. issue 2. 1980-03-17. PMID:393137. |
in the adult, four essential immunoreactions, corresponding to hormones or "local hormones" are regularly detected:insulin, pancreatic glucagon, somatostatin, pancreatic polypeptide. |
1980-03-17 |
2023-08-11 |
Not clear |
| V Schusdziarra, E Zyznar, D Rouiller, G Boden, J C Brown, A Arimura, R H Unge. Splanchnic somatostatin: a hormonal regulator of nutrient homeostasis. Science (New York, N.Y.). vol 207. issue 4430. 1980-03-17. PMID:7352262. |
neutralization of circulating somatostatin while the dogs were consuming a fatty meal increased the plasma concentrations of triglycerides, gastrin, pancreatic polypeptide, and insulin after the meal. |
1980-03-17 |
2023-08-12 |
dog |
| O N Danilevskai. [Expression of eukaryotic genes in Escherichia coli cells]. Genetika. vol 15. issue 12. 1980-02-28. PMID:389736. |
studies on bacterial synthesis of somatostatin, human insulin, hormone of rat growth and proteins: chicken ovalbumin and mouse dihydrofolate reductase are discussed. |
1980-02-28 |
2023-08-11 |
mouse |
| A Czyzyk, M Szadkowski, J Muszyńsk. The effect of somatostatin on the exocrine function of the pancreas and on serum insulin level in chronic relapsing pancreatitis. Acta medica Polona. vol 20. issue 3. 1980-02-28. PMID:517161. |
the effect of somatostatin on the exocrine function of the pancreas and on serum insulin level in chronic relapsing pancreatitis. |
1980-02-28 |
2023-08-11 |
Not clear |
| S R Friesen, J R Kimmel, T Tomit. Pancreatic polypeptide as screening marker for pancreatic polypeptide apudomas in multiple endocrinopathies. American journal of surgery. vol 139. issue 1. 1980-02-28. PMID:6243207. |
both tumors contained hpp predominantly by immunocytochemistry; one, a pure pancreatic polypeptide apudoma, was studied extensively demonstrating also by radioimmunoassay a high content of hpp and negligible amounts of insulin, glucagon, somatostatin, vasoactive intestinal polypeptide and gastrin. |
1980-02-28 |
2023-08-12 |
human |
| S R Friesen, J R Kimmel, T Tomit. Pancreatic polypeptide as screening marker for pancreatic polypeptide apudomas in multiple endocrinopathies. American journal of surgery. vol 139. issue 1. 1980-02-28. PMID:6243207. |
in this patient plasma concentrations of other polypeptides including insulin, glucagon, somatostatin, vasoactive intestinal polypeptide, gastrin, parathyrin, thyrocalcitonin, prolactin, corticotropin, growth hormone, thyrtropin and amine, serotonin, were within normal limits. |
1980-02-28 |
2023-08-12 |
human |
| K Hermansen, T W Schwart. Differential sensitivity to somatostatin of pancreatic polypeptide, glucagon and insulin secretion from the isolated perfused canine pancreas. Metabolism: clinical and experimental. vol 28. issue 12. 1980-02-26. PMID:514083. |
differential sensitivity to somatostatin of pancreatic polypeptide, glucagon and insulin secretion from the isolated perfused canine pancreas. |
1980-02-26 |
2023-08-11 |
Not clear |
| K Hermansen, T W Schwart. Differential sensitivity to somatostatin of pancreatic polypeptide, glucagon and insulin secretion from the isolated perfused canine pancreas. Metabolism: clinical and experimental. vol 28. issue 12. 1980-02-26. PMID:514083. |
this dose-response study deals with the relative inhibitory effect of somatostatin on the acetylcholine-stimulated release of pancreatic polypeptide (pp), glucagon, and insulin from the isolated canine pancrease. |
1980-02-26 |
2023-08-11 |
Not clear |
| K Hermansen, T W Schwart. Differential sensitivity to somatostatin of pancreatic polypeptide, glucagon and insulin secretion from the isolated perfused canine pancreas. Metabolism: clinical and experimental. vol 28. issue 12. 1980-02-26. PMID:514083. |
somatostatin in picomolar doses potently inhibited insulin and glucagon secretion, whereas pp secretion was relatively insensitive. |
1980-02-26 |
2023-08-11 |
Not clear |
| K Hermansen, T W Schwart. Differential sensitivity to somatostatin of pancreatic polypeptide, glucagon and insulin secretion from the isolated perfused canine pancreas. Metabolism: clinical and experimental. vol 28. issue 12. 1980-02-26. PMID:514083. |
also, in the absence of acetylcholine, somatostatin exerted a preferential inhibition of the release insulin and glucagon compared with pp. |
1980-02-26 |
2023-08-11 |
Not clear |
| K Hermansen, T W Schwart. Differential sensitivity to somatostatin of pancreatic polypeptide, glucagon and insulin secretion from the isolated perfused canine pancreas. Metabolism: clinical and experimental. vol 28. issue 12. 1980-02-26. PMID:514083. |
these findings point to a physiologically important role of somatostatin for the secretion of insulin and glucagon, but probably not for pp. |
1980-02-26 |
2023-08-11 |
Not clear |
| F Ginsberg-Fellner, E J Rayfiel. Metabolic studies in a child with a pancreatic insulinoma. American journal of diseases of children (1960). vol 134. issue 1. 1980-02-26. PMID:6243203. |
somatostatin infusion resulted in a modest increase in plasma glucose levels and a decrease in serum insulin concentrations. |
1980-02-26 |
2023-08-12 |
Not clear |
| T Ishida, S Röjdmark, G Bloom, M C Chou, J B Fiel. The effect of somatostatin on the hepatic extraction of insulin and glucagon in the anesthetized dog. Endocrinology. vol 106. issue 1. 1980-02-26. PMID:7349954. |
the effect of somatostatin on the hepatic extraction of insulin and glucagon in the anesthetized dog. |
1980-02-26 |
2023-08-12 |
dog |
| T Ishida, S Röjdmark, G Bloom, M C Chou, J B Fiel. The effect of somatostatin on the hepatic extraction of insulin and glucagon in the anesthetized dog. Endocrinology. vol 106. issue 1. 1980-02-26. PMID:7349954. |
during the final 50 min of the somatostatin or saline infusion, insulin (1.7 mu/kg . |
1980-02-26 |
2023-08-12 |
dog |
| T Ishida, S Röjdmark, G Bloom, M C Chou, J B Fiel. The effect of somatostatin on the hepatic extraction of insulin and glucagon in the anesthetized dog. Endocrinology. vol 106. issue 1. 1980-02-26. PMID:7349954. |
somatostatin rapidly and significantly decreased portal vein insulin and glucagon concentrations. |
1980-02-26 |
2023-08-12 |
dog |
| T Ishida, S Röjdmark, G Bloom, M C Chou, J B Fiel. The effect of somatostatin on the hepatic extraction of insulin and glucagon in the anesthetized dog. Endocrinology. vol 106. issue 1. 1980-02-26. PMID:7349954. |
hepatic extraction of endogenous insulin decreased from the control value of 61 +/- 5% to 29 +/- 10% during the final 20 min of somatostatin infusion before exogenous insulin and glucagon were added to the infusion. |
1980-02-26 |
2023-08-12 |
dog |
| T Ishida, S Röjdmark, G Bloom, M C Chou, J B Fiel. The effect of somatostatin on the hepatic extraction of insulin and glucagon in the anesthetized dog. Endocrinology. vol 106. issue 1. 1980-02-26. PMID:7349954. |
during the final 20 min of somatostatin infusion before the addition of insulin and glucagon, the blood glucose significantly decreased and hepatic glucose output fell from 2.4 +/- 0.4 to 1.4 +/- 0.3 mg/kg . |
1980-02-26 |
2023-08-12 |
dog |