| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Ishibashi, T Sato, K Onari, R Kawat. Effect of somatostatin on glucose-induced 45Ca uptake in the pancreatic islets. Endocrinologia japonica. vol 26. issue 5. 1980-04-23. PMID:393504. |
somatostatin inhibited preferentially the early phase of glucose-induced insulin release, whereas diltiazem hcl inhibited the late one. |
1980-04-23 |
2023-08-11 |
rat |
| F Ishibashi, T Sato, K Onari, R Kawat. Effect of somatostatin on glucose-induced 45Ca uptake in the pancreatic islets. Endocrinologia japonica. vol 26. issue 5. 1980-04-23. PMID:393504. |
these data indicate that somatostatin suppresses the early phase of glucose-induced ca2+ uptake preferentially to the late one and has a different action mechanism from ca antagonist on glucose-induced insulin release. |
1980-04-23 |
2023-08-11 |
rat |
| P E Lins, S Efendić, K Hal. Effect of 24-hour somatostatin infusion on glucose homeostasis and on the levels of somatomedin A and pancreatic and thyroid hormones in man. Acta medica Scandinavica. vol 206. issue 6. 1980-04-23. PMID:394578. |
in order to investigate whether somatostatin plays a role in the regulation of thyroid hormone secretion we have compared the effects of a prolonged somatostatin infusion on insulin and glucagon levels, on the one hand, with its effect on t4, t3, rt3 and tsh, on the other. |
1980-04-23 |
2023-08-11 |
Not clear |
| P E Lins, S Efendić, K Hal. Effect of 24-hour somatostatin infusion on glucose homeostasis and on the levels of somatomedin A and pancreatic and thyroid hormones in man. Acta medica Scandinavica. vol 206. issue 6. 1980-04-23. PMID:394578. |
somatostatin suppressed basal insulin and glucagon levels as well as insulin responses to meals but did not influence somatomedin a levels. |
1980-04-23 |
2023-08-11 |
Not clear |
| K H Usadel, U Schwedes, G Bastert, U Steinau, I Klempa, W Fassbinder, K Schöfflin. Transplantation of human fetal pancreas: experience in thymusaplastic mice and rats and in a diabetic patient. Diabetes. vol 29 Suppl 1. 1980-04-23. PMID:6986312. |
insulin, glucagon, somatostatin, and pancreatic polypeptide immunoreactivities were also seen in very early stages of the transplant development within the monolayered ducts. |
1980-04-23 |
2023-08-12 |
mouse |
| F Fallucca, C Mirabella, G Tamburrano, S Gambardella, G Aufieri, F Barbetti, D Andrean. Effects of somatostatin on insulin and glucagon in patients with insulinoma. Journal of endocrinological investigation. vol 2. issue 3. 1980-04-17. PMID:231062. |
effects of somatostatin on insulin and glucagon in patients with insulinoma. |
1980-04-17 |
2023-08-11 |
Not clear |
| F Fallucca, C Mirabella, G Tamburrano, S Gambardella, G Aufieri, F Barbetti, D Andrean. Effects of somatostatin on insulin and glucagon in patients with insulinoma. Journal of endocrinological investigation. vol 2. issue 3. 1980-04-17. PMID:231062. |
effects of somatostatin on fasting and arginine-or tolbutamide-stimulated insulin release were studied in four patients with insulinoma. |
1980-04-17 |
2023-08-11 |
Not clear |
| F Fallucca, C Mirabella, G Tamburrano, S Gambardella, G Aufieri, F Barbetti, D Andrean. Effects of somatostatin on insulin and glucagon in patients with insulinoma. Journal of endocrinological investigation. vol 2. issue 3. 1980-04-17. PMID:231062. |
somatostatin (bolus or bolus + infusion) reduced fasting insulin values in all patients; insulin response to tolbutamide was partially reduced in two patients; somatostatin bolus impaired the insulin response to arginine. |
1980-04-17 |
2023-08-11 |
Not clear |
| F Fallucca, C Mirabella, G Tamburrano, S Gambardella, G Aufieri, F Barbetti, D Andrean. Effects of somatostatin on insulin and glucagon in patients with insulinoma. Journal of endocrinological investigation. vol 2. issue 3. 1980-04-17. PMID:231062. |
these results indicate the potential usefulness of somatostatin in the diagnosis of insulinoma even if its effect on insulin is only partial. |
1980-04-17 |
2023-08-11 |
Not clear |
| L Mandarino, M Itoh, W Blanchard, G Patton, J Geric. Stimulation of insulin release in the absence of extracellular calcium by isobutylmethylxanthine and its inhibition by somatostatin. Endocrinology. vol 106. issue 2. 1980-04-17. PMID:6153357. |
stimulation of insulin release in the absence of extracellular calcium by isobutylmethylxanthine and its inhibition by somatostatin. |
1980-04-17 |
2023-08-12 |
rat |
| L Mandarino, M Itoh, W Blanchard, G Patton, J Geric. Stimulation of insulin release in the absence of extracellular calcium by isobutylmethylxanthine and its inhibition by somatostatin. Endocrinology. vol 106. issue 2. 1980-04-17. PMID:6153357. |
it has been suggested that somatostatin may inhibit insulin release by interfering with pancreatic islet calcium uptake. |
1980-04-17 |
2023-08-12 |
rat |
| L Mandarino, M Itoh, W Blanchard, G Patton, J Geric. Stimulation of insulin release in the absence of extracellular calcium by isobutylmethylxanthine and its inhibition by somatostatin. Endocrinology. vol 106. issue 2. 1980-04-17. PMID:6153357. |
to further investigate this hypothesis, the effect of somatostatin on insulin release was examined under conditions where islet uptake of calcium would be unlikely to occur. |
1980-04-17 |
2023-08-12 |
rat |
| L Mandarino, M Itoh, W Blanchard, G Patton, J Geric. Stimulation of insulin release in the absence of extracellular calcium by isobutylmethylxanthine and its inhibition by somatostatin. Endocrinology. vol 106. issue 2. 1980-04-17. PMID:6153357. |
since uptake of extracellular calcium by islets was unlikely under the present experimental conditions, these results suggest that somatostatin inhibition of insulin release is probably due to interference with a camp-dependent translocation of intraislet calcium, or to interference with some other effects of camp or an effect of calcium itself rather than to interference with islet calcium uptake. |
1980-04-17 |
2023-08-12 |
rat |
| A V Greco, A G Rebuzzi, L Altomonte, R Manna, A Bertoli, G Ghirland. Glucose, insulin and somatostatin infusion for the determination of insulin resistance in liver cirrhosis. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 11. issue 10. 1980-03-27. PMID:521009. |
glucose, insulin and somatostatin infusion for the determination of insulin resistance in liver cirrhosis. |
1980-03-27 |
2023-08-11 |
human |
| A V Greco, A G Rebuzzi, L Altomonte, R Manna, A Bertoli, G Ghirland. Glucose, insulin and somatostatin infusion for the determination of insulin resistance in liver cirrhosis. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 11. issue 10. 1980-03-27. PMID:521009. |
using a constant intravneous infusion of glucose, insulin and somatostatin over 2 1/2 hours we determined the stteady state plasma glucose level (sspg) in order to measure insulin resistance. |
1980-03-27 |
2023-08-11 |
human |
| J R Henderson, P M Danie. A comparative study of the portal vessels connecting the endocrine and exocrine pancreas, with a discussion of some functional implications. Quarterly journal of experimental physiology and cognate medical sciences. vol 64. issue 4. 1980-03-24. PMID:118478. |
some of the functional implications of these vascular connexions are discussed, particularly the influence of the islet hormones insulin, glucagon and somatostatin upon the exocrine cells. |
1980-03-24 |
2023-08-11 |
mouse |
| G C Weir, J A Schwarz, C J Math. Inhibition of glucagon and insulin secretion from the perfused rat pancreas by a B-cell-selective somatostatin analog. Metabolism: clinical and experimental. vol 29. issue 1. 1980-03-24. PMID:6986012. |
inhibition of glucagon and insulin secretion from the perfused rat pancreas by a b-cell-selective somatostatin analog. |
1980-03-24 |
2023-08-12 |
rat |
| G C Weir, J A Schwarz, C J Math. Inhibition of glucagon and insulin secretion from the perfused rat pancreas by a B-cell-selective somatostatin analog. Metabolism: clinical and experimental. vol 29. issue 1. 1980-03-24. PMID:6986012. |
the isolated perfused rat pancreas was used to study the effects of somatostatin and the analog des-asn5-[d-trps, d-ser13]-somatostatin on arginine-stimulated insulin and glucagon secretion. |
1980-03-24 |
2023-08-12 |
rat |
| G I Shulman, W W Lacy, J E Liljenquist, U Keller, P E Williams, A D Cherringto. Effect of glucose, independent of changes in insulin and glucagon secretion, on alanine metabolism in the conscious dog. The Journal of clinical investigation. vol 65. issue 2. 1980-03-24. PMID:7356691. |
to study the effects of hyperglycemia on the metabolism of alanine and lactate independent of changes in plasma insulin and glucagon, glucose was infused into five 36-h-fasted dogs along with somatostatin and constant replacement amounts of both insulin and glucagon. |
1980-03-24 |
2023-08-12 |
dog |
| S Efendić, F Enzmann, A Nylén, K Uvnäs-Wallensten, R Luf. Effect of glucose/sulfonylurea interaction on release of insulin, glucagon, and somatostatin from isolated perfused rat pancreas. Proceedings of the National Academy of Sciences of the United States of America. vol 76. issue 11. 1980-03-17. PMID:118458. |
effect of glucose/sulfonylurea interaction on release of insulin, glucagon, and somatostatin from isolated perfused rat pancreas. |
1980-03-17 |
2023-08-11 |
rat |