| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Hermanse. Pancreatic D-cell recognition of D-glucose: studies with D-glucose, D-glyceraldehyde, dihydroxyacetone, D-mannoheptulose, D-fructose, D-galactose, and D-ribose. Diabetes. vol 30. issue 3. 1981-05-21. PMID:6110600. |
(3) mannoheptulose (5 mm) attenuated somatostatin and insulin secretion to 8.3 mm glucose, while it augmented glucagon output. |
1981-05-21 |
2023-08-12 |
dog |
| K Hermanse. Pancreatic D-cell recognition of D-glucose: studies with D-glucose, D-glyceraldehyde, dihydroxyacetone, D-mannoheptulose, D-fructose, D-galactose, and D-ribose. Diabetes. vol 30. issue 3. 1981-05-21. PMID:6110600. |
(4) the somatostatin, insulin, and glucagon release remained unchanged when 8.3 mm of either galactose, fructose, or ribose was added. |
1981-05-21 |
2023-08-12 |
dog |
| S M Genuth, C L Hoppe. Acute hormonal effects on carnitine metabolism in thin and obese subjects: responses to somatostatin, glucagon, and insulin. Metabolism: clinical and experimental. vol 30. issue 4. 1981-05-21. PMID:6111018. |
acute hormonal effects on carnitine metabolism in thin and obese subjects: responses to somatostatin, glucagon, and insulin. |
1981-05-21 |
2023-08-12 |
human |
| S M Genuth, C L Hoppe. Acute hormonal effects on carnitine metabolism in thin and obese subjects: responses to somatostatin, glucagon, and insulin. Metabolism: clinical and experimental. vol 30. issue 4. 1981-05-21. PMID:6111018. |
the antiketogenic effect of adding glucagon was due to an eventual breakthrough of the somatostatin blockade on insulin secretion, the latter gradually returning toward preinfusion levels. |
1981-05-21 |
2023-08-12 |
human |
| Y Stefan, M Ravazzola, L Orc. Primitive islets contain two populations of cells with differing glucagon immunoreactivity. Diabetes. vol 30. issue 3. 1981-05-21. PMID:6162696. |
immunofluorescence staining with insulin, glucagon, and somatostatin antisera revealed different immunoreactive cell types in the pancreatic islets of the ratfish. |
1981-05-21 |
2023-08-12 |
Not clear |
| P Schauder, C McIntosh, L Herberg, J Arends, H Koop, H Frerichs, W Creutzfeld. Increased somatostatin secretion from pancreatic islets of streptozotocin-diabetic rats in response to glucose. Molecular and cellular endocrinology. vol 20. issue 3. 1981-05-13. PMID:6110594. |
glucose stimulates somatostatin release from perifused pancreatic islets of diabetic rats 42-47 days after the induction of diabetes, and 48 h after withdrawal of insulin replacement therapy. |
1981-05-13 |
2023-08-12 |
rat |
| Y Goto, M Berelowitz, L A Frohma. Acute effects of alloxan- and streptozotocin-induced insulin deficiency on somatostatin and glucagon secretion by the perfused isolated rat pancreatico-duodenal preparation. Diabetologia. vol 20. issue 1. 1981-05-13. PMID:6110604. |
acute effects of alloxan- and streptozotocin-induced insulin deficiency on somatostatin and glucagon secretion by the perfused isolated rat pancreatico-duodenal preparation. |
1981-05-13 |
2023-08-12 |
rat |
| Y Goto, M Berelowitz, L A Frohma. Acute effects of alloxan- and streptozotocin-induced insulin deficiency on somatostatin and glucagon secretion by the perfused isolated rat pancreatico-duodenal preparation. Diabetologia. vol 20. issue 1. 1981-05-13. PMID:6110604. |
the secretion of somatostatin and glucagon by the perfused rat pancreatico-duodenal preparation was examined in situ under control conditions and after the induction of acute insulin deficiency by alloxan or streptozotocin. |
1981-05-13 |
2023-08-12 |
rat |
| Y Goto, M Berelowitz, L A Frohma. Acute effects of alloxan- and streptozotocin-induced insulin deficiency on somatostatin and glucagon secretion by the perfused isolated rat pancreatico-duodenal preparation. Diabetologia. vol 20. issue 1. 1981-05-13. PMID:6110604. |
a 10 min 0.625 mmol/l alloxan perfusion resulted in an immediate and transient increase in basal insulin and glucagon release and a slightly delayed and persistent increase in basal somatostatin secretion. |
1981-05-13 |
2023-08-12 |
rat |
| Y Goto, M Berelowitz, L A Frohma. Acute effects of alloxan- and streptozotocin-induced insulin deficiency on somatostatin and glucagon secretion by the perfused isolated rat pancreatico-duodenal preparation. Diabetologia. vol 20. issue 1. 1981-05-13. PMID:6110604. |
addition of 1 microgram/ml porcine insulin to the perfusion medium did not modify the alterations in somatostatin and glucagon responses to arginine. |
1981-05-13 |
2023-08-12 |
rat |
| Y Goto, M Berelowitz, L A Frohma. Acute effects of alloxan- and streptozotocin-induced insulin deficiency on somatostatin and glucagon secretion by the perfused isolated rat pancreatico-duodenal preparation. Diabetologia. vol 20. issue 1. 1981-05-13. PMID:6110604. |
streptozotocin treatment 90 min prior to the onset of perfusion resulted in changes in somatostatin, glucagon, and insulin responses to glucose and arginine similar to those of alloxan. |
1981-05-13 |
2023-08-12 |
rat |
| P Metcalfe, D G Johnston, R Nosadini, H Orksov, K G Albert. Metabolic effects of acute and prolonged growth hormone excess in normal and insulin-deficient man. Diabetologia. vol 20. issue 2. 1981-05-13. PMID:6110606. |
the metabolic effects of acute (4 h) and prolonged (24 h) growth hormone excess at pathophysiological concentrations were studied by growth hormone administration to normal subjects with and without somatostatin induced insulin deficiency. |
1981-05-13 |
2023-08-12 |
human |
| P Metcalfe, D G Johnston, R Nosadini, H Orksov, K G Albert. Metabolic effects of acute and prolonged growth hormone excess in normal and insulin-deficient man. Diabetologia. vol 20. issue 2. 1981-05-13. PMID:6110606. |
when insulin secretion was suppressed by somatostatin, a hyperglycaemic effect of acute growth hormone excess was unmasked, and the hyperglycaemic effect of chronic growth hormone excess was exaggerated. |
1981-05-13 |
2023-08-12 |
human |
| P Metcalfe, D G Johnston, R Nosadini, H Orksov, K G Albert. Metabolic effects of acute and prolonged growth hormone excess in normal and insulin-deficient man. Diabetologia. vol 20. issue 2. 1981-05-13. PMID:6110606. |
acute growth hormone administration without somatostatin had a mild ketogenic action despite stimulated insulin secretion but no change in plasma non-esterified fatty acid or blood glycerol levels was observed. |
1981-05-13 |
2023-08-12 |
human |
| P Metcalfe, D G Johnston, R Nosadini, H Orksov, K G Albert. Metabolic effects of acute and prolonged growth hormone excess in normal and insulin-deficient man. Diabetologia. vol 20. issue 2. 1981-05-13. PMID:6110606. |
prolonged growth hormone excess had a lipolytic action that was increased by somatostatin, although the ketogenic effect of growth hormone was only seen during somatostatin induced insulin deficiency. |
1981-05-13 |
2023-08-12 |
human |
| b' P E Lins, B Petersson, S Efendi\\xc4\\x8. Effects of short-term and prolonged infusions of somatostatin on endocrine pancreas, body weight and food intake in rats. Acta physiologica Scandinavica. vol 110. issue 3. 1981-05-13. PMID:6111176.' |
the same dose of somatostatin applied 60 min prior to and during a 30 min load of glucose or arginine significantly inhibited their effects on insulin and glucagon release. |
1981-05-13 |
2023-08-12 |
rat |
| b' P E Lins, B Petersson, S Efendi\\xc4\\x8. Effects of short-term and prolonged infusions of somatostatin on endocrine pancreas, body weight and food intake in rats. Acta physiologica Scandinavica. vol 110. issue 3. 1981-05-13. PMID:6111176.' |
route it did not inhibit glucose induced insulin release though circulating somatostatin levels were constantly and markedly elevated. |
1981-05-13 |
2023-08-12 |
rat |
| b' P E Lins, B Petersson, S Efendi\\xc4\\x8. Effects of short-term and prolonged infusions of somatostatin on endocrine pancreas, body weight and food intake in rats. Acta physiologica Scandinavica. vol 110. issue 3. 1981-05-13. PMID:6111176.' |
furthermore, in rats continuously infused with somatostatin for 4 days, no effect was found either on plasma concentrations of glucose, insulin, glucagon, growth hormone and cyclic amp, or on body weight gain, food consumption or water intake. |
1981-05-13 |
2023-08-12 |
rat |
| b' P E Lins, B Petersson, S Efendi\\xc4\\x8. Effects of short-term and prolonged infusions of somatostatin on endocrine pancreas, body weight and food intake in rats. Acta physiologica Scandinavica. vol 110. issue 3. 1981-05-13. PMID:6111176.' |
our experiments demonstrate that, in short-term experiments in rats, somatostatin influences insulin and glucagon release as well as glucose homeostasis. |
1981-05-13 |
2023-08-12 |
rat |
| J E Geric. Somatostatin and diabetes. The American journal of medicine. vol 70. issue 3. 1981-05-13. PMID:6111219. |
somatostatin, a tetradecapeptide originally isolated from the hypothalamus on the basis of its ability to inhibit the secretion of growth hormone, is now known to be widely distributed in various endocrine and gastrointestinal tissues and to have diverse actions, including inhibition of insulin and glucagon secretion. |
1981-05-13 |
2023-08-12 |
Not clear |