| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Gupta, M H Stoler, L H Fossom, A W Tan. Tyrosine hydroxylase mRNA in the dopaminergic neurons of young adult and aged mice by in situ hybridization. Neuroscience letters. vol 119. issue 1. 1991-07-19. PMID:1982959. |
the results suggest that th gene expression in dopaminergic neurons of the sn and vta is not different in young adult and aged mice. |
1991-07-19 |
2023-08-11 |
mouse |
| E K O'Malley, I B Black, C F Dreyfu. Local support cells promote survival of substantia nigra dopaminergic neurons in culture. Experimental neurology. vol 112. issue 1. 1991-05-14. PMID:1672852. |
to examine the regulation of neuronal survival, we have studied the substantia nigra (sn) dopaminergic (da) system, in dissociated cell culture. |
1991-05-14 |
2023-08-11 |
Not clear |
| C Yoshihara, N Saito, K Taniyama, C Tanak. Differential localization of four subspecies of protein kinase C in the rat striatum and substantia nigra. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 11. issue 3. 1991-04-17. PMID:1672152. |
the double-staining and lesion studies revealed that the alpha-pkc-immunopositive neurons in the striatum were intrinsic cholinergic neurons, and that most of the alpha-pkc-immunoreactive neurons in the sn were dopaminergic neurons. |
1991-04-17 |
2023-08-11 |
rat |
| D M Gao, L Jeaugey, P Pollak, A L Benabi. Intensity-dependent nociceptive responses from presumed dopaminergic neurons of the substantia nigra, pars compacta in the rat and their modification by lateral habenula inputs. Brain research. vol 529. issue 1-2. 1991-03-19. PMID:2282499. |
the characteristics of nociceptive responses from presumed dopaminergic (daergic) neurons in the sn were investigated in the anesthetized rat with extracellular recordings. |
1991-03-19 |
2023-08-11 |
rat |
| T H McNeill, L L Koe. Differential effects of advancing age on neurotransmitter cell loss in the substantia nigra and striatum of C57BL/6N mice. Brain research. vol 521. issue 1-2. 1990-11-09. PMID:1976411. |
the present study was carried out to examine the extrapyramidal motor system of c57bl/6n mice for age-related cell loss in cholinergic neurons of the striatum (st) and dopaminergic (da) neurons of the substantia nigra (sn). |
1990-11-09 |
2023-08-11 |
mouse |
| H A Se. Differentiation gradient of dopaminergic neurons in substantia nigra of rat. Shi yan sheng wu xue bao. vol 23. issue 1. 1990-09-11. PMID:1974379. |
the chemical differentiation featured by the appearance of tyrosine hydroxylase (th) and the distribution pattern of the dopaminergic cells of rat substantia nigra (sn) were studied with combined immunocytochemical and electronmicroscopic techniques. |
1990-09-11 |
2023-08-11 |
rat |
| D J Doudet, C Gross, M Arluison, B Bioula. Modifications of precentral cortex discharge and EMG activity in monkeys with MPTP-induced lesions of DA nigral neurons. Experimental brain research. vol 80. issue 1. 1990-08-01. PMID:1972680. |
the dopaminergic (da) neurons of the substantia nigra (sn) were destroyed selectively by repeated series of intravenous injections of mptp. |
1990-08-01 |
2023-08-11 |
monkey |
| H Dabadie, N Mons, M Geffar. Simultaneous detection of tryptamine and dopamine in rat substantia nigra and raphe nuclei using specific antibodies. Brain research. vol 512. issue 1. 1990-06-21. PMID:2337800. |
secondly, using a monoclonal anti-dopamine (da) antibody and our anti-t antibodies, the simultaneous and specific detection of these compounds enabled us to define the spatial relationships existing between the dopaminergic and tryptaminergic neuronal systems from the substantia nigra (sn) to the raphe nuclei. |
1990-06-21 |
2023-08-11 |
rat |
| P N'Gouemo, M Lerner-Natoli, G Rondouin, K Watanabe, F Sandillon, A Privat, M Baldy-Moulinie. Catecholaminergic systems and amygdala kindling development. Effects of bilateral lesions of substantia nigra dopaminergic or locus coeruleus noradrenergic neurones. Epilepsy research. vol 5. issue 2. 1990-05-30. PMID:2109692. |
the effects of the bilateral and selective destruction of substantia nigra (sn) dopaminergic or locus coeruleus (lc) noradrenergic neurones, consecutive to a local injection of 6-hydroxydopamine, were studied on the development of amygdala kindling. |
1990-05-30 |
2023-08-11 |
Not clear |
| B Fornstedt, A Brun, E Rosengren, A Carlsso. The apparent autoxidation rate of catechols in dopamine-rich regions of human brains increases with the degree of depigmentation of substantia nigra. Journal of neural transmission. Parkinson's disease and dementia section. vol 1. issue 4. 1990-01-26. PMID:2597314. |
thus depigmentation and degeneration of dopaminergic sn neurons, seem to be correlated to enhanced rates of autoxidation, possibly due to an impaired antioxidant capacity. |
1990-01-26 |
2023-08-11 |
human |
| Y Solberg, Y Pollack, W F Silverma. Expression of tyrosine hydroxylase mRNA in transplanted fetal dopamine neurons. Neuroscience letters. vol 106. issue 1-2. 1990-01-04. PMID:2573868. |
compared to host sn neurons, the grafted dopaminergic cells expressed more message for the enzyme, while they showed lower amounts of the enzyme itself. |
1990-01-04 |
2023-08-11 |
Not clear |
| G S Robertson, H A Robertso. Evidence that L-dopa-induced rotational behavior is dependent on both striatal and nigral mechanisms. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 9. issue 9. 1989-11-07. PMID:2795165. |
this is accompanied by a loss of dopamine in brain regions, such as the corpus striatum, which receives input from dopaminergic neurons in the substantia nigra (sn). |
1989-11-07 |
2023-08-11 |
rat |
| R Barke. Adrenal grafting for Parkinson's disease: a role for substance P. The International journal of neuroscience. vol 46. issue 1-2. 1989-09-25. PMID:2475450. |
adrenal grafting for parkinson's disease: a role for substance p. parkinson's disease (pd) is a progressive neurodegenerative disorder in which the primary pathology is thought to be a loss of dopaminergic neurons in the substantia nigra (sn). |
1989-09-25 |
2023-08-11 |
Not clear |
| J C Chen, V D Ramire. In vivo dopaminergic activity from nucleus accumbens, substantia nigra and ventral tegmental area in the freely moving rat: basal neurochemical output and prolactin effect. Neuroendocrinology. vol 48. issue 4. 1989-02-21. PMID:2463493. |
in this paper, by means of a push-pull perfusion technique, we have examined the local effect of ovine prolactin (oprl) on the spontaneous in vivo dopaminergic (daergic) activity of the nucleus accumbens (nacc), substantia nigra (sn) and ventral tegmental area (vta) of living male rats. |
1989-02-21 |
2023-08-11 |
rat |
| M Hajós, G Engberg, H Nissbrandt, T Magnusson, A Carlsso. Capsaicin-sensitive vasodilatatory mechanisms in the rat substantia nigra and striatum. Journal of neural transmission. vol 74. issue 3. 1989-02-13. PMID:3210010. |
analyses of the levels of monoamines and their metabolites in the striatum following injection of capsaicin into the sn or cpu revealed that dopaminergic neurons are not primarily involved in this effect. |
1989-02-13 |
2023-08-11 |
rat |
| W J Friedman, C F Dreyfus, B McEwen, I B Blac. Presynaptic transmitters and depolarizing influences regulate development of the substantia nigra in culture. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 8. issue 10. 1989-01-03. PMID:2461433. |
development of the dopaminergic phenotype in the mouse substantia nigra (sn) was studied by monitoring tyrosine hydroxylase (th), the rate-limiting enzyme in ca biosynthesis in vivo and in culture. |
1989-01-03 |
2023-08-11 |
mouse |
| F Gra. [The neuropathology of Parkinson syndrome]. Revue neurologique. vol 144. issue 4. 1988-10-14. PMID:2843979. |
parkinsonism is due to an alteration of the dopaminergic nigro-striatal pathway the main morphological basis of which is a lesion of the substantia nigra (sn). |
1988-10-14 |
2023-08-11 |
Not clear |
| H Nabatame, M Sasa, S Takaori, M Kameyam. Muscarinic receptor-mediated inhibition of dopaminergic excitatory input to caudate neurons from the substantia nigra. Japanese journal of pharmacology. vol 46. issue 4. 1988-09-09. PMID:3404769. |
these results suggest that the muscarinic receptors located on the sn-derived dopaminergic nerve terminals mainly play a role in inhibiting inputs from the sn to the caudate neurons, probably by reducing the release of dopamine from the nerve terminals. |
1988-09-09 |
2023-08-11 |
rat |
| M Sasa, Y Ohno, S Takaor. Presynaptic inhibition of excitatory input from the substantia nigra to caudate nucleus neurons by a substituted quinolinone derivative, 7-[3-(4-(2,3-dimethylphenyl)piperazinyl)propoxy]-2(1H)-quinolinone (OPC-4392). Life sciences. vol 43. issue 3. 1988-08-31. PMID:3398698. |
these results suggest that opc-4392 acts on the dopaminergic nerve terminals and inhibits excitatory transmission from the sn to the cn. |
1988-08-31 |
2023-08-11 |
Not clear |
| G S Robertson, H A Robertso. Evidence that the substantia nigra is a site of action for L-DOPA. Neuroscience letters. vol 89. issue 2. 1988-08-22. PMID:3393296. |
the results are discussed in terms of dopaminergic regulation of the striatonigral pathway, their clinical relevance to parkinson's disease and the suggestion that the sn is an important site for the action of l-dopa. |
1988-08-22 |
2023-08-11 |
rat |