| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N König, V Han, E Lieth, J Laude. Effects of coculture on the morphology of identified raphe and substantia nigra neurons from the embryonic rat brain. Journal of neuroscience research. vol 17. issue 4. 1987-10-21. PMID:2887662. |
although this might suggest that there was a greater effect of coculture on the th-ir (dopaminergic) cells of the sn than on the 5-ht-ir cells of the rn, we must consider the fact that a significant population of th-ir cells were present in single rn cultures, which contributed to the total population of th-ir cells in cocultures. |
1987-10-21 |
2023-08-11 |
rat |
| K Morimoto, G V Goddar. The substantia nigra is an important site for the containment of seizure generalization in the kindling model of epilepsy. Epilepsia. vol 28. issue 1. 1987-02-19. PMID:3792287. |
the relative involvements of gabaergic gamma-aminobutyric acid and dopaminergic systems of the sn in this inhibitory function are discussed. |
1987-02-19 |
2023-08-11 |
rat |
| J D Elsworth, A Y Deutch, D E Redmond, J R Sladek, R H Rot. Differential responsiveness to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in sub-regions of the primate substantia nigra and striatum. Life sciences. vol 40. issue 2. 1987-02-11. PMID:3491946. |
the sn of asymptomatic animals had a slight increase in lipofuscin fluorescence within dopaminergic neurons and a small reduction in the number of dopaminergic cells, while fluorescent intensity of individual neurons was unchanged. |
1987-02-11 |
2023-08-11 |
monkey |
| R Barke. Substance P and Parkinson's disease: a causal relationship? Journal of theoretical biology. vol 120. issue 3. 1987-01-22. PMID:2431225. |
here i present evidence to show that pd may result from a primary loss of active tachykinin, probably substance p (sp) in the substantia nigra (sn), and that this loss leads to a secondary degeneration of the dopaminergic neurones. |
1987-01-22 |
2023-08-11 |
Not clear |
| B J Albala, S L Moshé, J F Cubells, N S Sharpless, M H Makma. Unilateral peri-substantia nigra catecholaminergic lesion and amygdala kindling. Brain research. vol 370. issue 2. 1986-06-27. PMID:3085869. |
in this report we investigated the role of the dopaminergic nigrostriatal pathway in mediating the sn effect on seizures by lesioning this pathway with unilateral infusions of 6-hydroxydopamine (6-ohda) in the vicinity of the right sn with or without desmethylimipramine pretreatment. |
1986-06-27 |
2023-08-11 |
rat |
| J M Durand-Gorde, J Bert, A Nieoullo. Changes in tyrosine hydroxylase, glutamic acid decarboxylase and choline acetyltransferase after local microinoculation of scrapie agent into the nigrostriatal system of the golden hamster. Brain research. vol 341. issue 2. 1985-11-04. PMID:2864098. |
the microinoculation of a homogenate of an infected brain unilaterally into the substantia nigra (sn) provokes a decrease in tyrosine hydroxylase (th), the synthesizing enzyme for dopamine in the dopaminergic neurones, in the striatum ipsilateral to the injected sn. |
1985-11-04 |
2023-08-11 |
Not clear |
| M Morelli, G Di Chiar. Non-dopaminergic mechanisms in the turning behavior evoked by intranigral opiates. Brain research. vol 341. issue 2. 1985-11-04. PMID:2864100. |
in order to study the role of the dopaminergic nigrostriatal system, we made unilateral lesions of the medial forebrain bundle (mfb) with 6-hydroxydopamine (6-ohda) and kainic acid lesions of the striatum and we looked at the effect elicited by these lesions on the behavior produced by the above compounds when injected into the sn. |
1985-11-04 |
2023-08-11 |
rat |
| M Morelli, G Di Chiar. Non-dopaminergic mechanisms in the turning behavior evoked by intranigral opiates. Brain research. vol 341. issue 2. 1985-11-04. PMID:2864100. |
the lesion of the dopaminergic nigrostriatal system failed to affect either the number of turns or the duration of the contralateral circling produced by unilateral injections of morphine, dynorphin and enkephalin analogs into the sn correspondent to the lesioned side. |
1985-11-04 |
2023-08-11 |
rat |
| J A Javitch, S M Strittmatter, S H Snyde. Differential visualization of dopamine and norepinephrine uptake sites in rat brain using [3H]mazindol autoradiography. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 5. issue 6. 1985-07-30. PMID:4009243. |
thus, the da uptake sites in the caudate-putamen are located on the presynaptic terminals of dopaminergic axons originating from the sn. |
1985-07-30 |
2023-08-11 |
rat |
| K N Duggal, S Baras. Electrical stimulation of the substantia nigra does not increase tail-flick latency in the rat. Experimental neurology. vol 87. issue 2. 1985-03-06. PMID:3967714. |
this effect was not due to current spread to dopaminergic neurons in the zona compacta compartment of the sn because administration of cis-flupenthixol failed to block the effect. |
1985-03-06 |
2023-08-11 |
rat |
| R Romo, A Chéramy, G Godeheu, J Glowinsk. Distinct commissural pathways are involved in the enhanced release of dopamine induced in the contralateral caudate nucleus and substantia nigra by unilateral application of GABA in the cat thalamic motor nuclei. Brain research. vol 308. issue 1. 1984-11-14. PMID:6383515. |
the effects of diencephalic or telencephalic commissural sectioning on the changes in [3h]dopamine ([3h]da) release from nerve terminals (in the caudate nucleus, cn) and dendrites (in the substantia nigra, sn) of the two nigro-striatal dopaminergic pathways induced by the application of gaba (10(-5) m, 30 min) into the left ventralis medialis (vm) or ventralis lateralis (vl) thalamic nuclei were investigated. |
1984-11-14 |
2023-08-12 |
cat |
| E G McGeer, P L McGee. Substantia nigra cell death from kainic acid or folic acid injections into the pontine tegmentum. Brain research. vol 298. issue 2. 1984-07-13. PMID:6144364. |
injections of kainic acid into the rostral pontine tegmentum in rats caused not only local lesions but destruction of gabaergic and dopaminergic cells in the substantia nigra (sn), as indicated histologically and by measurements of tyrosine hydroxylase (th) and glutamate decarboxylase (gad). |
1984-07-13 |
2023-08-12 |
rat |
| W J Free. Functional brain tissue transplantation: reversal of lesion-induced rotation by intraventricular substantia nigra and adrenal medulla grafts, with a note on intracranial retinal grafts. Biological psychiatry. vol 18. issue 11. 1984-02-14. PMID:6652162. |
the sn grafts produced a dopaminergic reinnervation of the dorsomedial striatum that appeared to be responsible for the behavioral amelioration. |
1984-02-14 |
2023-08-12 |
rat |
| M F Chesselet, A Chéramy, T D Reisine, C Lubetzki, M Desban, J Glowinsk. Local and distal effects induced by unilateral striatal application of opiates in the absence or in the presence of naloxone on the release of dopamine in both caudate nuclei and substantiae nigrae of the cat. Brain research. vol 258. issue 2. 1983-04-15. PMID:6824913. |
halothane-anesthetized cats implanted with push-pull cannulae in both caudate nuclei (cn) and substantiae nigrae (sn) were used to study the effects of naloxone and various opiates when applied into the left cn on the release of newly synthetized tritiated dopamine (da) from nerve terminals and dendrites of the two nigro-striatal dopaminergic pathways. |
1983-04-15 |
2023-08-12 |
cat |
| W H Oertel, M L Tappaz, A Berod, E Mugnain. Two-color immunohistochemistry for dopamine and GABA neurons in rat substantia nigra and zona incerta. Brain research bulletin. vol 9. issue 1-6. 1983-02-25. PMID:6129046. |
dopaminergic and gabaergic neurons were visualized in the same section of rat substantia nigra (sn) and zona incerta (zi) by a two-color double immunoperoxidase procedure or by double immunofluorescence. |
1983-02-25 |
2023-08-12 |
rat |
| W H Oertel, M L Tappaz, A Berod, E Mugnain. Two-color immunohistochemistry for dopamine and GABA neurons in rat substantia nigra and zona incerta. Brain research bulletin. vol 9. issue 1-6. 1983-02-25. PMID:6129046. |
this study suggests a dichotomy of both sn and zi into a predominantly dopaminergic and a predominantly gabaergic part. |
1983-02-25 |
2023-08-12 |
rat |
| J H Pazo, J H Medin. Changes in multiunit activity of nigral neurons induced by cholinergic and dopaminergic stimulation of the caudate nucleus. Brain research. vol 249. issue 2. 1983-01-19. PMID:6291714. |
in conclusion, our results indicate an opposite action of caudate cholinergic and dopaminergic receptors on multiunit activity in the sn of the cat. |
1983-01-19 |
2023-08-12 |
cat |
| C Vadasz, H Baker, T H Joh, A Lajtha, D J Rei. The inheritance and genetic correlation of tyrosine hydroxylase activities in the substantia nigra and corpus striatum in the C x B recombinant inbred mouse strains. Brain research. vol 234. issue 1. 1982-05-12. PMID:6120745. |
in mouse, strain differences in the activity of tyrosine hydroxylase (th) in ventral midbrain dopamine systems of substantia nigra-a10 (sn) region of mouse brain and in a terminal field, the striatum (cs), can be entirely attributed to variations in the number of dopaminergic neurons2. |
1982-05-12 |
2023-08-12 |
mouse |
| C Vadasz, H Baker, T H Joh, A Lajtha, D J Rei. The inheritance and genetic correlation of tyrosine hydroxylase activities in the substantia nigra and corpus striatum in the C x B recombinant inbred mouse strains. Brain research. vol 234. issue 1. 1982-05-12. PMID:6120745. |
assuming that our two measures reflect the number of dopaminergic neurons in sn-a10 area and density of their processes in corpus striatum, our results lead us to the hypothesis that the number of dopaminergic neurons and the axonal arborization of these neurons in the nigrostriatal system are in part under a common genetic control but that other genes may contribute to branching of sn neurons. |
1982-05-12 |
2023-08-12 |
mouse |
| Sharon Pay, S Baras. A study of the connections of nociceptive substantia nigra neurones. Pain. vol 12. issue 1. 1982-04-12. PMID:7058061. |
(iv) experiments were performed to determine whether nociceptive sn neurones were dopaminergic. |
1982-04-12 |
2023-08-12 |
rat |