| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sarah A Prins, Magdalena M Przybycien-Szymanska, Yathindar S Rao, Toni R Pa. Long-term effects of peripubertal binge EtOH exposure on hippocampal microRNA expression in the rat. PloS one. vol 9. issue 1. 2014-09-08. PMID:24416161. |
in addition, we measured the effects of binge etoh-exposure on hippocampal drosha and dicer mrna levels, as well as the putative mir target genes, bdnf and sirt1. |
2014-09-08 |
2023-08-12 |
rat |
| Xiao-Hong Li, Chong Chen, Yue Tu, Hong-Tao Sun, Ming-Liang Zhao, Shi-Xiang Cheng, Yang Qu, Sai Zhan. Sirt1 promotes axonogenesis by deacetylation of Akt and inactivation of GSK3. Molecular neurobiology. vol 48. issue 3. 2014-06-18. PMID:23475611. |
then, we found that genetic inhibition of sirt1 retarded axonal development in embryonic hippocampal neurons, whereas genetic and pharmacologic upregulation of sirt1 promoted not only the formation but also the elongation of axons. |
2014-06-18 |
2023-08-12 |
Not clear |
| L Sarga, N Hart, L G Koch, S L Britton, G Hajas, I Boldogh, X Ba, Z Rada. Aerobic endurance capacity affects spatial memory and SIRT1 is a potent modulator of 8-oxoguanine repair. Neuroscience. vol 252. 2014-06-11. PMID:23973402. |
these findings imply that high-running capacity is associated with increased hippocampal function, and sirt1 level/activity and inversely correlates with acogg1 levels and thereby the repair of genomic 8-oxog. |
2014-06-11 |
2023-08-12 |
rat |
| Jean-Louis Guéant, Jean-Luc Daval, Paul Vert, Jean-Pierre Nicola. [Folates and fetal programming: role of epigenetics and epigenomics]. Bulletin de l'Academie nationale de medecine. vol 196. issue 9. 2014-03-31. PMID:24552105. |
deficiency in folate and vitamin b12 produces impaired fatty acid oxidation in liver and heart through imbalanced methylation and acetylation of pgc1-alpha and decreased expression of sirt1, and long-lasting cognitive disabilities through impaired hippocampal cell proliferation, differentiation and plasticity and atrophy of hippocampal ca1. |
2014-03-31 |
2023-08-12 |
mouse |
| Sung Chung, Hee Jeong Kim, In Seon Yoon, Hyun Ju Kim, Sun Hye Choi, Yong Sik Kim, Kyung Ho Shi. Electroconvulsive shock increases SIRT1 immunoreactivity in the mouse hippocampus and hypothalamus. The journal of ECT. vol 29. issue 2. 2014-01-08. PMID:23519217. |
electroconvulsive shock increases sirt1 immunoreactivity in the mouse hippocampus and hypothalamus. |
2014-01-08 |
2023-08-12 |
mouse |
| Sung Chung, Hee Jeong Kim, In Seon Yoon, Hyun Ju Kim, Sun Hye Choi, Yong Sik Kim, Kyung Ho Shi. Electroconvulsive shock increases SIRT1 immunoreactivity in the mouse hippocampus and hypothalamus. The journal of ECT. vol 29. issue 2. 2014-01-08. PMID:23519217. |
the present study was designed to observe whether ecs dynamically regulates sirt1 levels in the hippocampus and hypothalamus; both of these regions have been implicated in the pathophysiology of depression. |
2014-01-08 |
2023-08-12 |
mouse |
| Jean-Louis Guéant, Fares Namour, Rosa-Maria Guéant-Rodriguez, Jean-Luc Dava. Folate and fetal programming: a play in epigenomics? Trends in endocrinology and metabolism: TEM. vol 24. issue 6. 2013-12-31. PMID:23474063. |
deficiency in folate and other methyl donors increases birth defects and produces visceral manifestations of fetal programming, including liver and heart steatosis, through imbalanced methylation and acetylation of pgc1-α and decreased sirt1 expression, and produces persistent cognitive and learning disabilities through impaired plasticity and hippocampal atrophy. |
2013-12-31 |
2023-08-12 |
Not clear |
| Amrita Datta Chaudhuri, Sowmya V Yelamanchili, Maria Cecilia G Marcondes, Howard S Fo. Up-regulation of microRNA-142 in simian immunodeficiency virus encephalitis leads to repression of sirtuin1. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 27. issue 9. 2013-11-12. PMID:23752207. |
sirtuin1 (sirt1) was predicted as a potential mir-142 target by analysis of its 3'-utr and bioinformatic analysis of factors linked to altered hippocampal gene expression profile in sive. |
2013-11-12 |
2023-08-12 |
human |
| Dae-Won Kim, Young-Mi Kim, Sung-Don Kang, Young-Min Han, Hyun-Ock Pa. Effects of Resveratrol and trans-3,5,4'-Trimethoxystilbene on Glutamate-Induced Cytotoxicity, Heme Oxygenase-1, and Sirtuin 1 in HT22 Neuronal Cells. Biomolecules & therapeutics. vol 20. issue 3. 2013-10-16. PMID:24130928. |
in this study, the effects of resveratrol and trans-3,5,4'-trimethoxystilbene (tms), a resveratrol derivative, on cytotoxicity caused by glutamate-induced oxidative stress, ho-1 expression, and sirt1 activation have been investigated by using murine hippocampal ht22 cells, which have been widely used as an in vitro model for investigating glutamate-induced neurotoxicity. |
2013-10-16 |
2023-08-12 |
Not clear |
| Sumiti Saharan, Dhanisha J Jhaveri, Perry F Bartlet. SIRT1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampus. Journal of neuroscience research. vol 91. issue 5. 2013-09-10. PMID:23404532. |
sirt1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampus. |
2013-09-10 |
2023-08-12 |
mouse |
| Sumiti Saharan, Dhanisha J Jhaveri, Perry F Bartlet. SIRT1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampus. Journal of neuroscience research. vol 91. issue 5. 2013-09-10. PMID:23404532. |
we show that sirt1 is expressed by proliferating adult subventricular zone and hippocampal neural precursors, although its transcript and protein levels are dramatically reduced during neural precursor differentiation. |
2013-09-10 |
2023-08-12 |
mouse |
| Sumiti Saharan, Dhanisha J Jhaveri, Perry F Bartlet. SIRT1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampus. Journal of neuroscience research. vol 91. issue 5. 2013-09-10. PMID:23404532. |
however, sirt1 knock down results in a significant increase in neuronal production in both the subventricular zone and the hippocampus. |
2013-09-10 |
2023-08-12 |
mouse |
| Sumiti Saharan, Dhanisha J Jhaveri, Perry F Bartlet. SIRT1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampus. Journal of neuroscience research. vol 91. issue 5. 2013-09-10. PMID:23404532. |
importantly, knock down of sirt1 in hippocampal precursors in vivo, either through rnai or through genetic ablation, promotes their neurogenic potential. |
2013-09-10 |
2023-08-12 |
mouse |
| Sumiti Saharan, Dhanisha J Jhaveri, Perry F Bartlet. SIRT1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampus. Journal of neuroscience research. vol 91. issue 5. 2013-09-10. PMID:23404532. |
these findings highlight sirt1 signaling as a negative regulator of neuronal differentiation of adult subventricular zone and hippocampal neural precursors. |
2013-09-10 |
2023-08-12 |
mouse |
| Tatiane Katsue Furuya, Patrícia Natália Oliveira da Silva, Spencer Luiz Marques Payão, Lucas Trevizani Rasmussen, Roger Willian de Labio, Paulo Henrique Ferreira Bertolucci, Ianna Lacerda Sampaio Braga, Elizabeth Suchi Chen, Gustavo Turecki, Naguib Mechawar, Jonathan Mill, Marília de Arruda Cardoso Smit. SORL1 and SIRT1 mRNA expression and promoter methylation levels in aging and Alzheimer's Disease. Neurochemistry international. vol 61. issue 7. 2013-06-05. PMID:22836009. |
as sorl1 (sortilin-related receptor) and sirt1 (sirtuin 1) genes have been linked to ad pathogenesis, we aimed to investigate their mrna expression and promoter dna methylation in post mortem brain tissues (entorhinal and auditory cortices and hippocampus) from healthy elderly subjects and ad patients. |
2013-06-05 |
2023-08-12 |
human |
| Juan F Codocedo, Claudio Allard, Juan A Godoy, Lorena Varela-Nallar, Nibaldo C Inestros. SIRT1 regulates dendritic development in hippocampal neurons. PloS one. vol 7. issue 10. 2013-05-31. PMID:23056585. |
sirt1 regulates dendritic development in hippocampal neurons. |
2013-05-31 |
2023-08-12 |
Not clear |
| Juan F Codocedo, Claudio Allard, Juan A Godoy, Lorena Varela-Nallar, Nibaldo C Inestros. SIRT1 regulates dendritic development in hippocampal neurons. PloS one. vol 7. issue 10. 2013-05-31. PMID:23056585. |
in the present study, the role of sirt1 in dendritic development was evaluated in cultured hippocampal neurons which were transfected at 3 days in vitro with a construct coding for sirt1 or for the dominant negative sirt1h363y, which lacks the catalytic activity. |
2013-05-31 |
2023-08-12 |
Not clear |
| Juan F Codocedo, Claudio Allard, Juan A Godoy, Lorena Varela-Nallar, Nibaldo C Inestros. SIRT1 regulates dendritic development in hippocampal neurons. PloS one. vol 7. issue 10. 2013-05-31. PMID:23056585. |
moreover, hippocampal neurons overexpressing sirt1 were resistant to dendritic dystrophy induced by aβ aggregates, an effect that was dependent on the deacetylase activity of sirt1. |
2013-05-31 |
2023-08-12 |
Not clear |
| Juan F Codocedo, Claudio Allard, Juan A Godoy, Lorena Varela-Nallar, Nibaldo C Inestros. SIRT1 regulates dendritic development in hippocampal neurons. PloS one. vol 7. issue 10. 2013-05-31. PMID:23056585. |
our findings indicate that sirt1 plays a role in the development and maintenance of dendritic branching in hippocampal neurons, and suggest that these effects are mediated by the rock signaling pathway. |
2013-05-31 |
2023-08-12 |
Not clear |
| Stefano Falone, Antonella D'Alessandro, Alessandro Mirabilio, Marisa Cacchio, Carmine Di Ilio, Silvia Di Loreto, Fernanda Amicarell. Late-onset running biphasically improves redox balance, energy- and methylglyoxal-related status, as well as SIRT1 expression in mouse hippocampus. PloS one. vol 7. issue 10. 2013-04-26. PMID:23110231. |
late-onset running biphasically improves redox balance, energy- and methylglyoxal-related status, as well as sirt1 expression in mouse hippocampus. |
2013-04-26 |
2023-08-12 |
mouse |