| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Elizabeth Linder, Kevin M Beggs, Robert J Burnett, Stephanie W Watt. Body distribution of infused serotonin in rats. Clinical and experimental pharmacology & physiology. vol 36. issue 5-6. 2009-11-24. PMID:19207716. |
mini-osmotic pumps containing 5-ht or vehicle were implanted in rats knocked out for sert (sert-ko) or in wild-type (wt) rats. |
2009-11-24 |
2023-08-12 |
rat |
| A Elizabeth Linder, Kevin M Beggs, Robert J Burnett, Stephanie W Watt. Body distribution of infused serotonin in rats. Clinical and experimental pharmacology & physiology. vol 36. issue 5-6. 2009-11-24. PMID:19207716. |
although 5-ht uptake in the kidney, seminal vesicle, prostate, jejunum and trachea is sert dependent, it is sert independent in the pancreas. |
2009-11-24 |
2023-08-12 |
rat |
| A Elizabeth Linder, Kevin M Beggs, Robert J Burnett, Stephanie W Watt. Body distribution of infused serotonin in rats. Clinical and experimental pharmacology & physiology. vol 36. issue 5-6. 2009-11-24. PMID:19207716. |
altogether, tissues from different systems, such as the cardiovascular, endocrine, genitourinary and gastrointestinal, accumulate 5-ht mainly via sert and, thus, these systems are potential targets for drugs that interfere with 5-ht homeostasis. |
2009-11-24 |
2023-08-12 |
rat |
| Alex Ward, Vyvyca J Walker, Zhaoyang Feng, X Z Shawn X. Cocaine modulates locomotion behavior in C. elegans. PloS one. vol 4. issue 6. 2009-11-17. PMID:19536276. |
cocaine, a potent addictive substance, is an inhibitor of monoamine transporters, including dat (dopamine transporter), sert (serotonin transporter) and net (norepinephrine transporter). |
2009-11-17 |
2023-08-12 |
caenorhabditis_elegans |
| Jacobi I Cunningham, Jamie Raudensky, John Tonkiss, Bryan K Yamamot. MDMA pretreatment leads to mild chronic unpredictable stress-induced impairments in spatial learning. Behavioral neuroscience. vol 123. issue 5. 2009-11-17. PMID:19824774. |
mdma pretreatment was hypothesized to enhance the effects of cus leading to enhanced 5-ht transporter (sert) depletion in the hippocampus and increased anxiety and cognitive impairment. |
2009-11-17 |
2023-08-12 |
rat |
| F S Hall, X-F Li, J Randall-Thompson, I Sora, D L Murphy, K-P Lesch, M Caron, G R Uh. Cocaine-conditioned locomotion in dopamine transporter, norepinephrine transporter and 5-HT transporter knockout mice. Neuroscience. vol 162. issue 4. 2009-11-10. PMID:19482066. |
the behavioral effects of cocaine are affected by gene knockout (ko) of the dopamine transporter (dat), the serotonin transporter (sert) and the norepinephrine transporter (net). |
2009-11-10 |
2023-08-12 |
mouse |
| N Matheus, C Mendoza, R Iceta, J E Mesonero, A I Alcald. Regulation of serotonin transporter activity by adenosine in intestinal epithelial cells. Biochemical pharmacology. vol 78. issue 9. 2009-11-10. PMID:19539610. |
the serotonin transporter (sert) expressed in the intestinal epithelium determines 5-ht availability and activity. |
2009-11-10 |
2023-08-12 |
human |
| Mélanie Viau, Julie Lafond, Cathy Vaillancour. Expression of placental serotonin transporter and 5-HT 2A receptor in normal and gestational diabetes mellitus pregnancies. Reproductive biomedicine online. vol 19. issue 2. 2009-11-09. PMID:19712556. |
the involvement of the serotonin transporter (sert) and 5-ht(2a) receptor (5-ht(2a)r) in diabetes has also been suggested. |
2009-11-09 |
2023-08-12 |
human |
| Mélanie Viau, Julie Lafond, Cathy Vaillancour. Expression of placental serotonin transporter and 5-HT 2A receptor in normal and gestational diabetes mellitus pregnancies. Reproductive biomedicine online. vol 19. issue 2. 2009-11-09. PMID:19712556. |
however, placental sert and 5-ht(2a)r have never been studied in gdm-complicated pregnancies. |
2009-11-09 |
2023-08-12 |
human |
| Mélanie Viau, Julie Lafond, Cathy Vaillancour. Expression of placental serotonin transporter and 5-HT 2A receptor in normal and gestational diabetes mellitus pregnancies. Reproductive biomedicine online. vol 19. issue 2. 2009-11-09. PMID:19712556. |
the aim of this study was to investigate the effect of gdm on the expression of both placental sert and 5-ht(2a)r. first, immunohistochemical analysis demonstrated the presence of sert and 5-ht(2a)r proteins in the villous trophoblast and the fetal capillary endothelium of normal term placental tissue. |
2009-11-09 |
2023-08-12 |
human |
| Mélanie Viau, Julie Lafond, Cathy Vaillancour. Expression of placental serotonin transporter and 5-HT 2A receptor in normal and gestational diabetes mellitus pregnancies. Reproductive biomedicine online. vol 19. issue 2. 2009-11-09. PMID:19712556. |
protein and mrna expression of sert and 5-ht(2a)r in the villous cytotrophoblastic and syncytiotrophoblastic cells was further confirmed in primary culture. |
2009-11-09 |
2023-08-12 |
human |
| Mélanie Viau, Julie Lafond, Cathy Vaillancour. Expression of placental serotonin transporter and 5-HT 2A receptor in normal and gestational diabetes mellitus pregnancies. Reproductive biomedicine online. vol 19. issue 2. 2009-11-09. PMID:19712556. |
a significantly (p < 0.05) decreased expression of sert mrna (56.3%) and protein (79.7%), and 5-ht(2a)r mrna (79.1%) and protein (29.1%) was observed in placental tissues from gdm compared with non-gdm pregnancies. |
2009-11-09 |
2023-08-12 |
human |
| Mélanie Viau, Julie Lafond, Cathy Vaillancour. Expression of placental serotonin transporter and 5-HT 2A receptor in normal and gestational diabetes mellitus pregnancies. Reproductive biomedicine online. vol 19. issue 2. 2009-11-09. PMID:19712556. |
these data suggest that sert and 5-ht(2a)r might be implicated in the aetiology of gdm. |
2009-11-09 |
2023-08-12 |
human |
| Mélanie Viau, Julie Lafond, Cathy Vaillancour. Expression of placental serotonin transporter and 5-HT 2A receptor in normal and gestational diabetes mellitus pregnancies. Reproductive biomedicine online. vol 19. issue 2. 2009-11-09. PMID:19712556. |
moreover, the presence of sert and 5-ht(2a)r in villous trophoblastic cells argues in favour of an important role of serotonin in human placental function. |
2009-11-09 |
2023-08-12 |
human |
| Zheng Zhou, Juan Zhen, Nathan K Karpowich, Christopher J Law, Maarten E A Reith, Da-Neng Wan. Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures. Nature structural & molecular biology. vol 16. issue 6. 2009-10-27. PMID:19430461. |
they exert their effects by inhibiting the presynaptic plasma membrane serotonin transporter (sert). |
2009-10-27 |
2023-08-12 |
Not clear |
| Julie L Wang, Ajit K Parhi, Shunichi Oya, Brian Lieberman, Hank F Kun. In vivo characterization of a series of 18F-diaryl sulfides (18F-2-(2'-((dimethylamino)methyl)-4'-(fluoroalkoxy)phenylthio)benzenamine) for PET imaging of the serotonin transporter. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 50. issue 9. 2009-10-22. PMID:19690040. |
pet of the serotonin transporter (sert) in the brain is a useful tool for examining normal physiologic functions as well as disease states involving the serotonergic system. |
2009-10-22 |
2023-08-12 |
Not clear |
| Nirmal S Bhide, Jack W Lipton, Jacobi I Cunningham, Bryan K Yamamoto, Gary A Gudelsk. Repeated exposure to MDMA provides neuroprotection against subsequent MDMA-induced serotonin depletion in brain. Brain research. vol 1286. 2009-10-20. PMID:19555677. |
the 5-ht depleting regimen of mdma also resulted in a 40-80% reduction in 5-ht transporter immunoreactivity (sert(ir)), and the reduction in sert(ir) also was completely attenuated in mdma-preconditioned animals. |
2009-10-20 |
2023-08-12 |
rat |
| Jennifer Joeyen-Waldorf, Nicole Edgar, Etienne Sibill. The roles of sex and serotonin transporter levels in age- and stress-related emotionality in mice. Brain research. vol 1286. 2009-10-20. PMID:19577546. |
the s/l promoter polymorphism in the serotonin transporter (sert) gene moderates both trait emotion and the vulnerability to develop depressive states in humans. |
2009-10-20 |
2023-08-12 |
mouse |
| Prashant S Kharkar, Angela M Batman, Juan Zhen, Patrick M Beardsley, Maarten E A Reith, Aloke K Dutt. Synthesis and biological characterization of (3R,4R)-4-(2-(benzhydryloxy)ethyl)-1-((R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol and its stereoisomers for activity toward monoamine transporters. ChemMedChem. vol 4. issue 7. 2009-10-08. PMID:19449323. |
interestingly, compounds 9 b and 9 d exhibit affinities for all three monoamine transporters, with highest potency at dat and net, and moderate potency at the serotonin transporter (sert) (k(i): 2.29, 78.4, and 155 nm for 9 b and 1.55, 14.1, and 259 nm for 9 d, respectively). |
2009-10-08 |
2023-08-12 |
mouse |
| L M Pavone, P Mithbaokar, V Mastellone, R Lo Muto, A Spina, V Maharajan, G Paino, L Avallon. Expression of the serotonin transporter (SERT) gene during mouse development. Veterinary research communications. vol 32 Suppl 1. 2009-09-30. PMID:18685991. |
expression of the serotonin transporter (sert) gene during mouse development. |
2009-09-30 |
2023-08-12 |
mouse |