| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tzung Lieh Yeh, I Hui Lee, Kao Ching Chen, Po See Chen, Wei Jen Yao, Yeng Kuang Yang, Nan Tsing Chiu, Ru Band L. The relationships between daily life events and the availabilities of serotonin transporters and dopamine transporters in healthy volunteers--a dual-isotope SPECT study. NeuroImage. vol 45. issue 2. 2009-05-13. PMID:19130891. |
the aim of this study was to examine the relationships between the daily life events and the availabilities of serotonin transporters (sert) and dopamine transporters (dat) in healthy volunteers. |
2009-05-13 |
2023-08-12 |
human |
| Stephan C Bischoff, Reiner Mailer, Oliver Pabst, Gisela Weier, Wanda Sedlik, Zhishan Li, Jason J Chen, Dennis L Murphy, Michael D Gersho. Role of serotonin in intestinal inflammation: knockout of serotonin reuptake transporter exacerbates 2,4,6-trinitrobenzene sulfonic acid colitis in mice. American journal of physiology. Gastrointestinal and liver physiology. vol 296. issue 3. 2009-04-28. PMID:19095763. |
the serotonin reuptake transporter (sert; slc6a4), which inactivates 5-ht, is expressed in the intestinal mucosa and the enteric nervous system. |
2009-04-28 |
2023-08-12 |
mouse |
| Stephan C Bischoff, Reiner Mailer, Oliver Pabst, Gisela Weier, Wanda Sedlik, Zhishan Li, Jason J Chen, Dennis L Murphy, Michael D Gersho. Role of serotonin in intestinal inflammation: knockout of serotonin reuptake transporter exacerbates 2,4,6-trinitrobenzene sulfonic acid colitis in mice. American journal of physiology. Gastrointestinal and liver physiology. vol 296. issue 3. 2009-04-28. PMID:19095763. |
we tested the hypotheses that 5-ht plays a role in regulating intestinal inflammation and that the potentiation of serotonergic signaling that results from sert deletion is proinflammatory. |
2009-04-28 |
2023-08-12 |
mouse |
| Steven M Bromidge, Barbara Bertani, Manuela Borriello, Stefania Faedo, Laurie J Gordon, Enrica Granci, Matthew Hill, Howard R Marshall, Luigi P Stasi, Valeria Zucchelli, Giancarlo Merlo, Alessia Vesentini, Jeannette M Watson, Laura Zonzin. 6-[2-(4-Aryl-1-piperazinyl)ethyl]-2H-1,4-benzoxazin-3(4H)-ones: dual-acting 5-HT1 receptor antagonists and serotonin reuptake inhibitors. Bioorganic & medicinal chemistry letters. vol 18. issue 20. 2009-04-24. PMID:18799312. |
investigation of a series 6-[2-(4-aryl-1-piperazinyl)ethyl]-2h-1,4-benzoxazin-3(4h)-ones has led to the discovery of potent 5-ht(1a/1b/1d) receptor antagonists with and without additional sert affinity. |
2009-04-24 |
2023-08-12 |
Not clear |
| Robin Spille. Serotonin and GI clinical disorders. Neuropharmacology. vol 55. issue 6. 2009-04-14. PMID:18687345. |
inflammation in animal models acts via t lymphocytes to increase ec cell numbers and mucosal serotonin (5-ht) content while inflammatory cytokines decrease serotonin transporter (sert) function. |
2009-04-14 |
2023-08-12 |
Not clear |
| Robin Spille. Serotonin and GI clinical disorders. Neuropharmacology. vol 55. issue 6. 2009-04-14. PMID:18687345. |
inflammation due to coeliac disease and following gastrointestinal infection increases mucosal 5-ht availability by a combination of increased ec cells and depressed sert. |
2009-04-14 |
2023-08-12 |
Not clear |
| T Deltheil, B P Guiard, J Cerdan, D J David, K F Tanaka, C Repérant, J-P Guilloux, F Coudoré, R Hen, A M Gardie. Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice. Neuropharmacology. vol 55. issue 6. 2009-04-14. PMID:18761360. |
(1) in heterozygous bdnf+/- mice in which brain bdnf protein levels were decreased by half, an enhancement of basal extracellular 5-ht levels (5-htext) that induced a down-regulation of sert, i.e., a decrease in its capacity to reuptake 5-ht, was found in the hippocampus. |
2009-04-14 |
2023-08-12 |
mouse |
| T Deltheil, B P Guiard, J Cerdan, D J David, K F Tanaka, C Repérant, J-P Guilloux, F Coudoré, R Hen, A M Gardie. Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice. Neuropharmacology. vol 55. issue 6. 2009-04-14. PMID:18761360. |
however, the decreased capacity of sert to reuptake 5-ht was not associated to an increase in basal 5-htext in the hippocampus of wt mice. |
2009-04-14 |
2023-08-12 |
mouse |
| Nicolas Narboux-Nême, Luigi Michele Pavone, Luigi Avallone, Xiaoxi Zhuang, Patricia Gaspa. Serotonin transporter transgenic (SERTcre) mouse line reveals developmental targets of serotonin specific reuptake inhibitors (SSRIs). Neuropharmacology. vol 55. issue 6. 2009-04-14. PMID:18789954. |
the serotonin transporter gene (slc6a4; synonyms, sert, 5-htt) is expressed much more broadly during development than in adulthood. |
2009-04-14 |
2023-08-12 |
mouse |
| Nicolas Narboux-Nême, Luigi Michele Pavone, Luigi Avallone, Xiaoxi Zhuang, Patricia Gaspa. Serotonin transporter transgenic (SERTcre) mouse line reveals developmental targets of serotonin specific reuptake inhibitors (SSRIs). Neuropharmacology. vol 55. issue 6. 2009-04-14. PMID:18789954. |
to obtain a full picture of all sites of sert expression during development we used a new mouse model where cre recombinase was inserted into the gene encoding the serotonin transporter. |
2009-04-14 |
2023-08-12 |
mouse |
| Nicolas Narboux-Nême, Luigi Michele Pavone, Luigi Avallone, Xiaoxi Zhuang, Patricia Gaspa. Serotonin transporter transgenic (SERTcre) mouse line reveals developmental targets of serotonin specific reuptake inhibitors (SSRIs). Neuropharmacology. vol 55. issue 6. 2009-04-14. PMID:18789954. |
this fate map of serotonin transporter expressing cells emphasizes the broad expression of sert in non-serotonin neurons during development and clarifies the localization of sert expression in the hippocampus and limbic cortex. |
2009-04-14 |
2023-08-12 |
mouse |
| Yejun Zhao, Lena Su. Antidepressants modulate the in vitro inhibitory effects of propofol and ketamine on norepinephrine and serotonin transporter function. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 15. issue 11. 2009-04-14. PMID:18815045. |
norepinephrine transporter (net) and serotonin transporter (sert) proteins regulate norepinephrine (ne) and serotonin via their reuptake function and are targets of antidepressants action. |
2009-04-14 |
2023-08-12 |
Not clear |
| Yejun Zhao, Lena Su. Antidepressants modulate the in vitro inhibitory effects of propofol and ketamine on norepinephrine and serotonin transporter function. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 15. issue 11. 2009-04-14. PMID:18815045. |
we examined the effect of different iv anesthetics on net and sert function, with and without chronic antidepressant pretreatment, by measuring ne or 5-hydroxytryptamine (5-ht) uptake and determined net and sert protein expression via immunoblotting. |
2009-04-14 |
2023-08-12 |
Not clear |
| Dennis L Murphy, Meredith A Fox, Kiara R Timpano, Pablo R Moya, Renee Ren-Patterson, Anne M Andrews, Andrew Holmes, Klaus-Peter Lesch, Jens R Wendlan. How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems. Neuropharmacology. vol 55. issue 6. 2009-04-14. PMID:18824000. |
the serotonin transporter (sert) has been the most comprehensively studied of the serotonin system molecular components, and will be the primary focus of this review. |
2009-04-14 |
2023-08-12 |
mouse |
| R Ramakrishnan, R Sheeladevi, A Namasivaya. Regulation of protein kinases and coregulatory interplay of S-100beta and serotonin transporter on serotonin levels in diabetic rat brain. Journal of neuroscience research. vol 87. issue 1. 2009-04-08. PMID:18711746. |
however, our consecutive studies have shown that the 5-ht level in pm was regulated by p38-mitogen-activated protein kinase (p38-mapk) both in vivo and in vitro, whereas the 5-ht level in ccx was coregulated by s-100beta by protein-protein interaction with serotonin transporter (sert) via 8-bromoadenosine 3',5'-cyclic monophosphate sodium salt (8-br-camp)-induced camp/pkaii pathway(s). |
2009-04-08 |
2023-08-12 |
rat |
| Kristen A Horner, Erika S Noble, Edward C Lauterbac. Differential regulation of prodynophin, c-fos, and serotonin transporter mRNA following withdrawal from a chronic, escalating dose regimen of D-amphetamine. Synapse (New York, N.Y.). vol 63. issue 4. 2009-04-08. PMID:19116947. |
changes in the serotonin transporter (sert) have also been reported in mdd, and changes in the immediate early gene c-fos have been observed in the context of psychostimulant withdrawal. |
2009-04-08 |
2023-08-12 |
rat |
| Morgane Thomsen, F Scott Hall, George R Uhl, S Barak Cain. Dramatically decreased cocaine self-administration in dopamine but not serotonin transporter knock-out mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 4. 2009-04-08. PMID:19176817. |
we tested the hypotheses that mice lacking the dopamine transporter (dat(-/-)), the serotonin transporter (sert(-/-)), or both (dat(-/-)sert(-/-)) exhibit decreased reinforcing effects of cocaine. |
2009-04-08 |
2023-08-12 |
mouse |
| Saloua Benmansour, Jonathan P Piotrowski, Alfonso V Altamirano, Alan Fraze. Impact of ovarian hormones on the modulation of the serotonin transporter by fluvoxamine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 3. 2009-03-30. PMID:18322468. |
blockade of serotonin transporter (sert) function by selective serotonin reuptake inhibitors (ssris) is the initial event that triggers a not completely understood process that results in clinical improvement in depression. |
2009-03-30 |
2023-08-12 |
rat |
| Saloua Benmansour, Jonathan P Piotrowski, Alfonso V Altamirano, Alan Fraze. Impact of ovarian hormones on the modulation of the serotonin transporter by fluvoxamine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 3. 2009-03-30. PMID:18322468. |
to investigate whether there are differences in the ability of ssris to inhibit the sert between male and female rats at different phases of the estrous cycle, clearance of locally applied serotonin (5-ht) was measured by in vivo chronoamperometry. |
2009-03-30 |
2023-08-12 |
rat |
| A Cupello, C Albano, E Gatta, S Scarrone, E Villa, G Zon. Binding of paroxetine to the serotonin transporter in membranes from different cells, subcellular fractions and species. Neurochemical research. vol 34. issue 2. 2009-03-30. PMID:18563559. |
the binding of [(3)h]-paroxetine to membrane serotonin transporter (sert) has been studied in membranes from different sources and subcellular fractions. |
2009-03-30 |
2023-08-12 |
human |