| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christopher J O'Connell, Evan L Reeder, Sean M Collins, Kainat Lungani, Sophia V Norman, Matthew J Robso. Mild traumatic brain injury elicits time- and region-specific reductions in serotonin transporter protein expression and uptake capacity. Neuroreport. vol 33. issue 14. 2022-09-05. PMID:36062511. |
these studies illustrate the critical importance of ongoing research efforts to characterize the molecular effects of various forms of neurotrauma on sert protein expression and function, which may yield novel drug targets within 5-ht systems. |
2022-09-05 |
2023-08-14 |
Not clear |
| Jessica Cornell, Andrew Conchas, Xin-Qun Wang, Jeffrey C Fink, Hegang Chen, Maureen A Kane, Nageswara Pilli, Nassima Ait-Daoud, David A Gorelick, Ming D Li, Bankole A Johnson, Chamindi Seneviratn. Validation of serotonin transporter mRNA as a quantitative biomarker of heavy drinking and its comparison to ethyl glucuronide/ethyl sulfate: A randomized, double-blind, crossover trial. Alcoholism, clinical and experimental research. 2022-08-29. PMID:36031718. |
the serotonin transporter (sert) mrna was previously reported as a quantitative and pathophysiology-based biomarker of heavy drinking in 5httlpr:ll genotype-carriers treated with ondansetron. |
2022-08-29 |
2023-08-14 |
Not clear |
| Margaret R MacLean, Barry Fanburg, Nicolas Hill, Howard M Lazarus, Thomas F Pack, Michelle Palacios, Krishna C Penumatsa, Stephen A Wrin. Serotonin and Pulmonary Hypertension; Sex and Drugs and ROCK and Rho. Comprehensive Physiology. vol 12. issue 4. 2022-08-29. PMID:36036567. |
in humans, serotonin enters pasmcs cells via the serotonin transporter (sert) and it can cooperate with the 5-ht1b receptor on the plasma membrane; this activates both contractile and proliferative signaling pathways. |
2022-08-29 |
2023-08-14 |
Not clear |
| Margaret R MacLean, Barry Fanburg, Nicolas Hill, Howard M Lazarus, Thomas F Pack, Michelle Palacios, Krishna C Penumatsa, Stephen A Wrin. Serotonin and Pulmonary Hypertension; Sex and Drugs and ROCK and Rho. Comprehensive Physiology. vol 12. issue 4. 2022-08-29. PMID:36036567. |
the "serotonin hypothesis of pulmonary hypertension" arose when serotonin was associated with pah induced by diet pills such as fenfluramine, aminorex, and chlorphentermine; these act as indirect serotonergic agonists causing the release of serotonin from platelets and cells through the sert. |
2022-08-29 |
2023-08-14 |
Not clear |
| Cristiano Bombardi, Giulia Salamanca, Claudio Tagliavia, Annamaria Grandis, Fanny Mille, Maria Grazia De Iorio, Giulietta Minozz. Immunohistochemical Distribution of Serotonin Transporter (SERT) in the Optic Lobe of the Honeybee, Animals : an open access journal from MDPI. vol 12. issue 16. 2022-08-26. PMID:36009622. |
immunohistochemical distribution of serotonin transporter (sert) in the optic lobe of the honeybee, visual information is processed in the optic lobes, which consist of three retinotopic neuropils. |
2022-08-26 |
2023-08-14 |
Not clear |
| Cristiano Bombardi, Giulia Salamanca, Claudio Tagliavia, Annamaria Grandis, Fanny Mille, Maria Grazia De Iorio, Giulietta Minozz. Immunohistochemical Distribution of Serotonin Transporter (SERT) in the Optic Lobe of the Honeybee, Animals : an open access journal from MDPI. vol 12. issue 16. 2022-08-26. PMID:36009622. |
the aim of this investigation was to immunohistochemically localize the distribution of serotonin transporter (sert) in the optic lobe of moderate, docile and aggressive worker honeybees. |
2022-08-26 |
2023-08-14 |
Not clear |
| Diego Del Alamo, Lillian DeSousa, Rahul M Nair, Suhaila Rahman, Jens Meiler, Hassane S Mchaoura. Integrated AlphaFold2 and DEER investigation of the conformational dynamics of a pH-dependent APC antiporter. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 34. 2022-08-15. PMID:35969794. |
its structure, determined in an inward-facing conformation at alkaline ph, consists of the canonical leut-fold with a conserved five-helix inverted repeat, thereby resembling functionally divergent transporters such as the serotonin transporter sert and the glucose-sodium symporter sglt1. |
2022-08-15 |
2023-08-14 |
Not clear |
| Andréa V Maglione, Bruna P P do Nascimento, Miriam O Ribeiro, Talytha J L de Souza, Renata E C da Silva, Monica A Sato, Carlos A A Penatti, Luiz R G Britto, Janaina S de Souza, Rui M B Maciel, Rodrigo Rodrigues da Conceição, Roberto Laureano-Melo, Gisele Giannocc. Triiodothyronine Treatment reverses Depression-Like Behavior in a triple-transgenic animal model of Alzheimer's Disease. Metabolic brain disease. 2022-08-11. PMID:35951206. |
when compared to control hippocampal samples, the t3 group exhibited attenuated glycogen synthase kinase-3 (gsk3), metalloproteinase 10 (adam10), amyloid-beta precursor-protein (app), serotonin transporter (sert), 5ht1a receptor, monocarboxylate transporter 8 (mct8) and bone morphogenetic protein 7 (bmp-7) gene expression, whereas augmented superoxide dismutase 2 (sod2) and hairless gene expression. |
2022-08-11 |
2023-08-14 |
mouse |
| Ayodele Oyadeyi, Folasade Ajao, Temitope Babalola, Yusuf Mustaph. Effects of Ruzu, a Polyherbal Mixture, on Neurobehaviour and Expression of Serotonin and Dopamine Transporters in Rats. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. vol 36. issue 2. 2022-08-10. PMID:35947744. |
animals were subsequently sacrificed and the expression of serotonin transporter (sert) and dopamine transporter (dat) was determined in the striatum by immunofluorescence while specific activities of catalase, alkaline phosphatase and gamma glutamyltransferase were determined. |
2022-08-10 |
2023-08-14 |
rat |
| Remi Janet, Romain Ligneul, Annabel B Losecaat-Vermeer, Remi Philippe, Gabriele Bellucci, Edmund Derrington, Soyoung Q Park, Jean-Claude Drehe. Regulation of social hierarchy learning by serotonin transporter availability. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-08-09. PMID:35945275. |
here we determined the relationship between serotonin transporter (sert) availability and brain systems engaged in learning social ranks combining computational approaches with simultaneous pet-fmri acquisition in healthy males. |
2022-08-09 |
2023-08-14 |
Not clear |
| Sahir Hussain, Heidi M D Lesscher, Darren J Day, Bart A Ellenbroe. Genetics and epigenetics: paternal adolescent ethanol consumption in serotonin transporter knock-out rats and offspring sensitivity to ethanol. Psychopharmacology. 2022-08-08. PMID:35939082. |
one of the genes associated with aud is slc6a4 (solute carrier family 6 member a4) which codes for the serotonin transporter (sert). |
2022-08-08 |
2023-08-14 |
rat |
| Sahir Hussain, Heidi M D Lesscher, Darren J Day, Bart A Ellenbroe. Genetics and epigenetics: paternal adolescent ethanol consumption in serotonin transporter knock-out rats and offspring sensitivity to ethanol. Psychopharmacology. 2022-08-08. PMID:35939082. |
the study looked at serotonin dysfunction on ethanol consumption in adolescents and the subsequent intergenerational effects of drinking by using a rat model: sert |
2022-08-08 |
2023-08-14 |
rat |
| Camilla Borgsted, Emma Hoegsted, Susanne Henningsson, Anja Pinborg, Melanie Ganz, Vibe G Frokjae. Hippocampal volume changes in a pharmacological sex-hormone manipulation risk model for depression in women. Hormones and behavior. vol 145. 2022-07-29. PMID:35905507. |
in a pharmacological sex-hormone manipulation model, we previously reported that estradiol reductions, induced with a gonadotropin-releasing hormone agonist (gnrha), provoked subclinical depressive symptoms in healthy women, especially if neocortical serotonin transporter (sert) binding also increased. |
2022-07-29 |
2023-08-14 |
Not clear |
| Chi-Jung Tsai, Chuang-Hsin Chiu, Yu-Yeh Kuo, Wen-Sheng Huang, Tsung-Hsun Yu, Leo Garcia Flores, Skye Hsin-Hsien Yeh, Kuo-Hsing M. Amitriptyline Accelerates SERT Binding Recovery in a Rat 3,4-Methylenedioxymethamphetamine (MDMA) Model: In Vivo 4-[ International journal of molecular sciences. vol 23. issue 13. 2022-07-09. PMID:35806049. |
amitriptyline accelerates sert binding recovery in a rat 3,4-methylenedioxymethamphetamine (mdma) model: in vivo 4-[ numerous studies have confirmed that 3,4-methylenedioxymethamphetamine (mdma) produces long-lasting changes to the density of the serotonin reuptake transporter (sert). |
2022-07-09 |
2023-08-14 |
rat |
| Rudy Schreiber, Una Campbell, Maria S Quinton, Larry W Hardy, Q Kevin Fang, Robert Le. In vitro and in vivo pharmacological characterization of dasotraline, a dual dopamine and norepinephrine transporter inhibitor in vivo. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 153. 2022-07-05. PMID:35785702. |
inhibitors of dopamine transporters (dat), norepinephrine transporters (net) and serotonin transporters (sert) are effective treatments for neuropsychiatric diseases. |
2022-07-05 |
2023-08-14 |
Not clear |
| Jasmin N Beaver, Brady L Weber, Matthew T Ford, Anna E Anello, Sarah K Kassis, T Lee Gilma. Uncovering Functional Contributions of PMAT ( Cells. vol 11. issue 12. 2022-06-24. PMID:35741002. |
uncovering functional contributions of pmat ( plasma membrane monoamine transporter (pmat, slc29a4) transports monoamine neurotransmitters, including dopamine and serotonin, faster than more studied monoamine transporters, e.g., dopamine transporter (dat), or serotonin transporter (sert), but with ~400-600-fold less affinity. |
2022-06-24 |
2023-08-14 |
mouse |
| Camilla Borgsted, Stinne Høgh, Emma Sofie Høgsted, Laura Fonnesbech-Sandberg, Kim Ekelund, Charlotte Krebs Albrechtsen, Julie Therese Wiis, Hanne Hegaard, Eleonora Cvetanovska, Anders Juul, Hanne Frederiksen, Anja Pinborg, Pia Weikop, Vibe Frokjae. The role of central serotonergic markers and estradiol changes in perinatal mental health. Acta psychiatrica Scandinavica. 2022-06-22. PMID:35729864. |
the serotonin transporter (sert) may be involved in the emergence of depressive symptoms postpartum and during other sex-hormone transitions. |
2022-06-22 |
2023-08-14 |
Not clear |
| Roberto Laureano-Melo, Raoni Conceição Dos-Santos, Rodrigo Rodrigues da Conceição, Janaina Sena de Souza, Claudio da Silva Almeida, Luís Carlos Reis, Bruno Guimarães Marinho, Gisele Giannocco, Ahmed Rg, Wellington da Silva Côrte. Neonatal D-fenfluramine Treatment Promotes Long-Term Behavioral Changes in Adult Mice. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-06-19. PMID:35718760. |
the programmed animals had a decrease in 5ht1a, serotonin transporter (sert), and brain-derived neurotrophic factor (bdnf) expression in the mesencephalic raphe region. |
2022-06-19 |
2023-08-14 |
mouse |
| Yu Gu, Chen Wang, Xiali Qin, Bingqian Zhou, Xiang Liu, Tianyu Liu, Runxiang Xie, Jinghua Liu, Bangmao Wang, Hailong Ca. Saccharomyces boulardii, a yeast probiotic, inhibits gut motility through upregulating intestinal serotonin transporter and modulating gut microbiota. Pharmacological research. 2022-06-11. PMID:35690329. |
the abnormal serotonin transporter (sert) / 5-hydroxytryptamine (5-ht) system could cause disordered gastrointestinal sensation and motility, which closely related to ibs pathogenesis. |
2022-06-11 |
2023-08-14 |
mouse |
| John Sebastiani, Allyson Sabatelli, M Danielle McDonal. Mild hypoxia exposure impacts peripheral serotonin uptake and degradation in Gulf toadfish, Opsanus beta. The Journal of experimental biology. 2022-06-06. PMID:35662341. |
plasma 5-ht homeostasis is maintained through the combined processes of uptake (via the 5-ht transporter sert, and others), degradation (via monoamine oxidase, mao), and excretion. |
2022-06-06 |
2023-08-14 |
Not clear |