| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Annette Leibetseder, Judith Wagner, Josef Tomasits, Hans-Peter Haring, Markus Hutterer, Johannes Trenkler, Tim J von Oertze. Spontaneous Intracerebral Hemorrhage Due to Delta Storage Pool Disease in a Patient on a Serotonin-Norepinephrine Reuptake Inhibitor. Frontiers in neurology. vol 10. 2020-10-01. PMID:31849820. |
increased susceptibility to snri-effects on hemostasis was due to a genetic disposition mediated by a polymorphism of the slc6a4 gene coding for the human serotonin transporter (sert). |
2020-10-01 |
2023-08-13 |
human |
| Gregory M James, Pia Baldinger-Melich, Cecile Philippe, Georg S Kranz, Thomas Vanicek, Andreas Hahn, Gregor Gryglewski, Marius Hienert, Marie Spies, Tatjana Traub-Weidinger, Markus Mitterhauser, Wolfgang Wadsak, Marcus Hacker, Siegfried Kasper, Rupert Lanzenberge. Effects of Selective Serotonin Reuptake Inhibitors on Interregional Relation of Serotonin Transporter Availability in Major Depression. Frontiers in human neuroscience. vol 11. 2020-09-30. PMID:28220069. |
here, we use positron emission tomography (pet) to quantify ssri's main target, the serotonin transporter (sert), and assess treatment-induced molecular changes in the interregional relation of sert binding potential (bp |
2020-09-30 |
2023-08-13 |
Not clear |
| Sonja Sucic, Ameya Kasture, H M Mazhar Asjad, Carina Kern, Ali El-Kasaby, Michael Freissmut. When transporters fail to be transported: how to rescue folding-deficient SLC6 transporters. Journal of neurology & neuromedicine. vol 1. issue 9. 2020-09-30. PMID:28405636. |
the folding trajectory of dat itself is not understood, though many insights have been gained from studies of folding-deficient mutants of the closely related serotonin transporter (sert); i.e. |
2020-09-30 |
2023-08-13 |
human |
| E Zoons, J Booij, J D Speelman, Y E M Dreissen, M Smit, M A J Tijsse. Lower serotonin transporter binding in patients with cervical dystonia is associated with psychiatric symptoms. EJNMMI research. vol 7. issue 1. 2020-09-30. PMID:29071431. |
we hypothesized that cd is associated with reduced serotonin transporter (sert) binding, more specific that sert binding is lower in cd patients with psychiatric symptoms and/or jerks/tremor compared to those without, and to controls. |
2020-09-30 |
2023-08-13 |
Not clear |
| Margaret Mandy R MacLea. The serotonin hypothesis in pulmonary hypertension revisited: targets for novel therapies (2017 Grover Conference Series). Pulmonary circulation. vol 8. issue 2. 2020-09-30. PMID:29468941. |
pulmonary endothelial serotonin synthesis via tryptophan hydroxlase 1 (tph1) is increased in patients with pah and serotonin can act in a paracrine fashion on underlying pulmonary arterial smooth muscle cells (pasmcs), in humans, serotonin can enter pasmcs via the serotonin transporter (sert) or activate the 5-ht1b receptor; 5-ht1b activation and sert activity cooperate to induce pasmc contraction and proliferation via activation of downstream proliferative and contractile signaling pathways. |
2020-09-30 |
2023-08-13 |
Not clear |
| Mark W Burke, Myriam Fillion, Jose Mejia, Frank R Ervin, Roberta M Palmou. Perinatal MAO Inhibition Produces Long-Lasting Impairment of Serotonin Function in Offspring. Brain sciences. vol 8. issue 6. 2020-09-30. PMID:29891804. |
the goal of the present study was to determine the extent to which this treatment influences dopamine and serotonin innervation of murine cortical and subcortical areas, as measured by regional density of dopamine (dat) and serotonin transporters (sert). |
2020-09-30 |
2023-08-13 |
Not clear |
| Glauce Socorro de Barros Viana, Cecilia Coelho Xavier, Eduardo Mulato do Vale, Maria Janice Pereira Lopes, Viviane de Jesus Alves, Roberta de Oliveira Costa, Kelly Rose Tavares Neve. The monoaminergic pathways and inhibition of monoamine transporters interfere with the antidepressive-like behavior of ketamine. IBRO reports. vol 4. 2020-09-30. PMID:30135946. |
in addition dat and sert (da and 5-ht transporters, respectively) were also assessed. |
2020-09-30 |
2023-08-13 |
mouse |
| Glauce Socorro de Barros Viana, Cecilia Coelho Xavier, Eduardo Mulato do Vale, Maria Janice Pereira Lopes, Viviane de Jesus Alves, Roberta de Oliveira Costa, Kelly Rose Tavares Neve. The monoaminergic pathways and inhibition of monoamine transporters interfere with the antidepressive-like behavior of ketamine. IBRO reports. vol 4. 2020-09-30. PMID:30135946. |
the results indicate that ket antidepressive-like effect probably involves, among other factors, monoaminergic pathways, as suggested by the increased striatal th immunoreactivity and reduced brain da (dat) and 5-ht (sert) transporters. |
2020-09-30 |
2023-08-13 |
mouse |
| Wen-Sheng Huang, Guann-Juh Chen, Tung-Han Tsai, Chen-Yi Cheng, Chyng-Yann Shiue, Kuo-Hsing Ma, Skye Hsin-Hsien Ye. In vivo long-lasting alterations of central serotonin transporter activity and associated dopamine synthesis after acute repeated administration of methamphetamine. EJNMMI research. vol 9. issue 1. 2020-09-30. PMID:31535286. |
methamphetamine (meth)-associated alterations in the striatal dopamine (da) system or dopamine transport (dat) have been identified in clinical and preclinical studies with positron emission tomography (pet) imaging but have not been well correlated with in vivo serotonin transporter (sert) availability due to the lack of appropriate imaging agents to assess serts. |
2020-09-30 |
2023-08-13 |
Not clear |
| Jun Zhao, Huiling Tian, Hongtao Song, Xu Wang, Tong Luo, Liya Ai, Yumin Fang, Jianghao Zhao, Saiyin Chao-Ke-Tu, Zhigang L. Effect of Electroacupuncture on Reuptake of Serotonin via miRNA-16 Expression in a Rat Model of Depression. Evidence-based complementary and alternative medicine : eCAM. vol 2019. 2020-09-30. PMID:31929820. |
after ea treatment for 4 weeks, behavioral changes and indices including 5-ht transporter (sert), 5-ht, and mirna-16 levels in the hippocampus and serum were examined. |
2020-09-30 |
2023-08-13 |
rat |
| Mojgan Mohammadi, Hossein Tahmasebi Abdar, Hamid Reza Mollaei, Hossein Hajghani, Mohammad Reza Baneshi, Mohammad Mahdi Hayatbakhs. Serotonin Transporter Gene (SLC6A4) Polymorphism and Mucosal Serotonin Levels in Southeastern Iranian Patients with Irritable Bowel Syndrome. Middle East journal of digestive diseases. vol 9. issue 1. 2020-09-29. PMID:28316763. |
polymorphism in serotonin re-uptake transporter (sert or slc6a4) gene may have a functional role in the gut of patients with ibs. |
2020-09-29 |
2023-08-13 |
Not clear |
| Hope Pan, Michael R Dohn, Rody Kingston, Ana M D Carneir. Integrin αVβ3 Function Influences Citalopram Immobility Behavior in the Tail Suspension Test. Frontiers in neuroscience. vol 13. 2020-09-29. PMID:30787865. |
human studies first identified genetic and expression interactions between integrin β3 and serotonin (5-ht) transporter (sert) genes. |
2020-09-29 |
2023-08-13 |
mouse |
| Kimberly B Schauder, Christopher L Muller, Jeremy Veenstra-VanderWeele, Carissa J Casci. Genetic Variation in Serotonin Transporter Modulates Tactile Hyperresponsiveness in ASD. Research in autism spectrum disorders. vol 10. 2020-09-28. PMID:25558276. |
specifically, the serotonin transporter (5-htt, sert) has been scrutinized as an asd candidate risk gene. |
2020-09-28 |
2023-08-13 |
human |
| Ekaterina Veniaminova, Raymond Cespuglio, Irina Chernukha, Angelika G Schmitt-Boehrer, Sergey Morozov, Allan V Kalueff, Oxana Kuznetsova, Daniel C Anthony, Klaus-Peter Lesch, Tatyana Strekalov. Metabolic, Molecular, and Behavioral Effects of Western Diet in Serotonin Transporter-Deficient Mice: Rescue by Heterozygosity? Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32132889. |
reduced function of the serotonin transporter (sert) is associated with increased susceptibility to anxiety and depression and with type-2 diabetes, which is especially true in older women. |
2020-09-28 |
2023-08-13 |
mouse |
| Prerna Jha, Lotten Ragnarsson, Richard J Lewi. Structure-Function of the High Affinity Substrate Binding Site (S1) of Human Norepinephrine Transporter. Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32210813. |
the human norepinephrine transporter (hnet) is a member of the neurotransmitter/sodium symporter family, which also includes the neuronal monoamine transporters for serotonin (sert) and dopamine (dat). |
2020-09-28 |
2023-08-13 |
human |
| Zi-Wen Zhong, Wen-Chang Zhou, Xing-Feng Sun, Qi-Chao Wu, Wan-Kun Chen, Chang-Hong Mia. Dezocine regulates the malignant potential and aerobic glycolysis of liver cancer targeting Akt1/GSK-3β pathway. Annals of translational medicine. vol 8. issue 7. 2020-09-28. PMID:32395524. |
former studies find dezocine inhibits the norepinephrine transporters (net) and serotonin transporters (sert) and sigma-1opioid receptors. |
2020-09-28 |
2023-08-13 |
Not clear |
| Geng Qin, Yu Zhang, Shu-Kun Ya. Serotonin transporter and cholecystokinin in diarrhea-predominant irritable bowel syndrome: Associations with abdominal pain, visceral hypersensitivity and psychological performance. World journal of clinical cases. vol 8. issue 9. 2020-09-28. PMID:32432141. |
previous studies have found that cholecystokinin (cck) can enhance colon movement and that serotonin transporter (sert) is a transmembrane transport protein with high affinity for 5-hydroxytryptamine, which can rapidly reuptake 5-hydroxytryptamine and then regulate its action time and intensity. |
2020-09-28 |
2023-08-13 |
Not clear |
| Meagan A Quinlan, Matthew J Robson, Ran Ye, Kristie L Rose, Kevin L Schey, Randy D Blakel. Frontiers in molecular neuroscience. vol 13. 2020-09-28. PMID:32581705. |
the presynaptic, high-affinity 5-ht transporter (sert) tightly regulates 5-ht clearance after release from serotonergic neurons in the brain and enteric nervous systems, among other sites. |
2020-09-28 |
2023-08-13 |
human |
| Gabriel Araujo Tavares, Amada Torres, Julliet Araujo de Souz. Early Life Stress and the Onset of Obesity: Proof of MicroRNAs' Involvement Through Modulation of Serotonin and Dopamine Systems' Homeostasis. Frontiers in physiology. vol 11. 2020-09-28. PMID:32848865. |
the first pieces of evidence highlight the presence of the mir-16 in the regulation of the serotonin transporter (sert) as well as the receptors 1a (5ht1a) and 2a (5ht2a). |
2020-09-28 |
2023-08-13 |
Not clear |
| Karine Roversi, Carolina Buizza, Paola Brivio, Francesca Calabrese, Michel M M Verheij, Caren T D Antoniazzi, Marilise E Burger, Marco A Riva, Judith R Homber. Neonatal Tactile Stimulation Alters Behaviors in Heterozygous Serotonin Transporter Male Rats: Role of the Amygdala. Frontiers in behavioral neuroscience. vol 14. 2020-09-28. PMID:32903627. |
the serotonin transporter (sert) gene, especially the short allele of the human serotonin transporter linked polymorphic region (5-httlpr), has been associated with the development of stress-related neuropsychiatric disorders. |
2020-09-28 |
2023-08-13 |
human |