| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna M S Kindlundh-Högberg, Helgi B Schiöth, Per Svenningsso. Repeated intermittent MDMA binges reduce DAT density in mice and SERT density in rats in reward regions of the adolescent brain. Neurotoxicology. vol 28. issue 6. 2008-02-07. PMID:17692920. |
behavioral responses in the open-field and autoradiographic ligand-binding to dopamine (dat) and serotonin (sert) transporters in reward regions of the brain were measured. |
2008-02-07 |
2023-08-12 |
mouse |
| Matthew L Banks, Paul W Czoty, H Donald Gage, Michael C Bounds, Pradeep K Garg, Sudha Garg, Michael A Nade. Effects of cocaine and MDMA self-administration on serotonin transporter availability in monkeys. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 2. 2008-02-06. PMID:17443127. |
the present study assessed 5-ht transporter (sert) availability using positron emission tomography (pet) in rhesus monkeys with the sert-specific radioligand [(11)c]3-amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-benzonitrile (dasb). |
2008-02-06 |
2023-08-12 |
human |
| Matthew L Banks, Paul W Czoty, H Donald Gage, Michael C Bounds, Pradeep K Garg, Sudha Garg, Michael A Nade. Effects of cocaine and MDMA self-administration on serotonin transporter availability in monkeys. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 2. 2008-02-06. PMID:17443127. |
the higher level of sert availability in cocaine-experienced monkeys may lead to a reduced inhibitory tone of 5-ht on the da system, which may explain, in part, differences in the abuse liability between cocaine and mdma. |
2008-02-06 |
2023-08-12 |
human |
| T Montgomery, C Buon, S Eibauer, P J Guiry, A K Keenan, G J McBea. Comparative potencies of 3,4-methylenedioxymethamphetamine (MDMA) analogues as inhibitors of [3H]noradrenaline and [3H]5-HT transport in mammalian cell lines. British journal of pharmacology. vol 152. issue 7. 2008-02-05. PMID:17891159. |
since monoamine transporters are one of the primary targets of mdma action in the brain, a number of mdma analogues have been tested for their ability to inhibit [3h]noradrenaline uptake into rat pc12 cells expressing the noradrenaline transporter (net) and [3h]5-ht uptake into hek293 cells stably transfected with the 5-ht transporter (sert). |
2008-02-05 |
2023-08-12 |
rat |
| Judith R Homberg, Tommy Pattij, Mieke C W Janssen, Eric Ronken, Sietse F De Boer, Anton N M Schoffelmeer, Edwin Cuppe. Serotonin transporter deficiency in rats improves inhibitory control but not behavioural flexibility. The European journal of neuroscience. vol 26. issue 7. 2008-01-29. PMID:17897403. |
in the present study we addressed the effect of lifelong reduced or absent serotonin transporter (sert) function, which is associated with constitutively increased extracellular 5-ht levels, on impulsivity and aggression. |
2008-01-29 |
2023-08-12 |
rat |
| Judith R Homberg, Tommy Pattij, Mieke C W Janssen, Eric Ronken, Sietse F De Boer, Anton N M Schoffelmeer, Edwin Cuppe. Serotonin transporter deficiency in rats improves inhibitory control but not behavioural flexibility. The European journal of neuroscience. vol 26. issue 7. 2008-01-29. PMID:17897403. |
we determined monoamine (metabolite) tissue levels in the medial prefrontal cortex, orbitofrontal cortex, lateral hypothalamus, raphe nuclei and cerebrospinal fluid, and found that the 5-ht levels, but not other monoamine tissue levels, were reduced in sert( -/-) rats. |
2008-01-29 |
2023-08-12 |
rat |
| Judith R Homberg, Tommy Pattij, Mieke C W Janssen, Eric Ronken, Sietse F De Boer, Anton N M Schoffelmeer, Edwin Cuppe. Serotonin transporter deficiency in rats improves inhibitory control but not behavioural flexibility. The European journal of neuroscience. vol 26. issue 7. 2008-01-29. PMID:17897403. |
in conclusion, our data show that the absence of the sert affects aggression and inhibitory control, but not behavioural flexibility, characteristics that may reflect the trait-like consequences of constitutive changes in central 5-ht levels. |
2008-01-29 |
2023-08-12 |
rat |
| G B Yang, C L Qiu, P Aye, Y Shao, A A Lackne. Expression of serotonin transporters by peripheral blood mononuclear cells of rhesus monkeys (Macaca mulatta). Cellular immunology. vol 248. issue 2. 2008-01-21. PMID:17980355. |
although the presence of 5-ht receptor mrnas in peripheral blood mononuclear cells (pbmcs) of rhesus monkeys has been reported, there is little information about serotonin transporter (sert) expression by these cells. |
2008-01-21 |
2023-08-12 |
monkey |
| G B Yang, C L Qiu, P Aye, Y Shao, A A Lackne. Expression of serotonin transporters by peripheral blood mononuclear cells of rhesus monkeys (Macaca mulatta). Cellular immunology. vol 248. issue 2. 2008-01-21. PMID:17980355. |
these data demonstrate expression of sert by rhesus macaque pbmcs, and indicate that rhesus macaques would be suitable models to test the in vivo immune regulatory effects of 5-ht or drugs targeting sert. |
2008-01-21 |
2023-08-12 |
monkey |
| Cassandra M Miller-Butterworth, Jay R Kaplan, M Michael Barmada, Stephen B Manuck, Robert E Ferrel. The serotonin transporter: sequence variation in Macaca fascicularis and its relationship to dominance. Behavior genetics. vol 37. issue 5. 2008-01-18. PMID:17605101. |
specific genotypes of the rhesus monkey and human serotonin transporter gene (sert) promoter region are associated with personality traits and serotonergic activity. |
2008-01-18 |
2023-08-12 |
human |
| Luigi M Pavone, Simona Tafuri, Vincenzo Mastellone, Rossella Della Morte, Pietro Lombardi, Luigi Avallone, Veeramani Maharajan, Norma Staiano, Gaetano Scal. Expression of the serotonin transporter (SERT) in the choroid plexuses from buffalo brain. Anatomical record (Hoboken, N.J. : 2007). vol 290. issue 12. 2008-01-17. PMID:17957753. |
expression of the serotonin transporter (sert) in the choroid plexuses from buffalo brain. |
2008-01-17 |
2023-08-12 |
Not clear |
| Luigi M Pavone, Simona Tafuri, Vincenzo Mastellone, Rossella Della Morte, Pietro Lombardi, Luigi Avallone, Veeramani Maharajan, Norma Staiano, Gaetano Scal. Expression of the serotonin transporter (SERT) in the choroid plexuses from buffalo brain. Anatomical record (Hoboken, N.J. : 2007). vol 290. issue 12. 2008-01-17. PMID:17957753. |
the serotonin transporter (sert) regulates the entire serotonergic system, including serotonin receptors by means of modulation of serotonin concentration in the extracellular fluid. |
2008-01-17 |
2023-08-12 |
Not clear |
| Luigi M Pavone, Simona Tafuri, Vincenzo Mastellone, Rossella Della Morte, Pietro Lombardi, Luigi Avallone, Veeramani Maharajan, Norma Staiano, Gaetano Scal. Expression of the serotonin transporter (SERT) in the choroid plexuses from buffalo brain. Anatomical record (Hoboken, N.J. : 2007). vol 290. issue 12. 2008-01-17. PMID:17957753. |
we suggest that sert might have an important role in mammalian cps, possibly regulating the serotonin flow between brain and rest of the body. |
2008-01-17 |
2023-08-12 |
Not clear |
| Yohtaro Numachi, Arihisa Ohara, Motoyasu Yamashita, Setsu Fukushima, Hideaki Kobayashi, Harumi Hata, Hidekazu Watanabe, F Scott Hall, Klaus-Peter Lesch, Dennis L Murphy, George R Uhl, Ichiro Sor. Methamphetamine-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters. European journal of pharmacology. vol 572. issue 2-3. 2008-01-14. PMID:17673199. |
we examined the hyperthermic and lethal toxic effects of methamphetamine in dopamine transporter (dat) and/or serotonin transporter (sert) knockout (ko) mice. |
2008-01-14 |
2023-08-12 |
mouse |
| Meredith A Fox, Catherine L Jensen, Pamela S Gallagher, Dennis L Murph. Receptor mediation of exaggerated responses to serotonin-enhancing drugs in serotonin transporter (SERT)-deficient mice. Neuropharmacology. vol 53. issue 5. 2008-01-14. PMID:17765930. |
receptor mediation of exaggerated responses to serotonin-enhancing drugs in serotonin transporter (sert)-deficient mice. |
2008-01-14 |
2023-08-12 |
mouse |
| Meredith A Fox, Catherine L Jensen, Pamela S Gallagher, Dennis L Murph. Receptor mediation of exaggerated responses to serotonin-enhancing drugs in serotonin transporter (SERT)-deficient mice. Neuropharmacology. vol 53. issue 5. 2008-01-14. PMID:17765930. |
we previously reported that mice with a targeted disruption of the serotonin transporter (sert) display some of these behaviors spontaneously, in the absence of drug. |
2008-01-14 |
2023-08-12 |
mouse |
| Meredith A Fox, Catherine L Jensen, Pamela S Gallagher, Dennis L Murph. Receptor mediation of exaggerated responses to serotonin-enhancing drugs in serotonin transporter (SERT)-deficient mice. Neuropharmacology. vol 53. issue 5. 2008-01-14. PMID:17765930. |
in the current studies, we assessed the drug-induced serotonin syndrome in sert wildtype (+/+), heterozygous (+/-) and knockout (-/-) mice. |
2008-01-14 |
2023-08-12 |
mouse |
| Meredith A Fox, Catherine L Jensen, Pamela S Gallagher, Dennis L Murph. Receptor mediation of exaggerated responses to serotonin-enhancing drugs in serotonin transporter (SERT)-deficient mice. Neuropharmacology. vol 53. issue 5. 2008-01-14. PMID:17765930. |
in sert -/- mice, the monoamine oxidase inhibitor (maoi) tranylcypromine (1mg/kg) or the serotonin precursor 5-hydroxy-l-tryptophan (5-htp; 80 mg/kg) led to markedly exaggerated serotonin syndrome behaviors relative to sert +/+ mice, with an intermediate phenotype in sert +/- mice. |
2008-01-14 |
2023-08-12 |
mouse |
| Meredith A Fox, Catherine L Jensen, Pamela S Gallagher, Dennis L Murph. Receptor mediation of exaggerated responses to serotonin-enhancing drugs in serotonin transporter (SERT)-deficient mice. Neuropharmacology. vol 53. issue 5. 2008-01-14. PMID:17765930. |
sert +/+ mice developed significant serotonin syndrome behaviors only with the combination of the mao-a/b inhibitor tranylcypromine (0.5 or 1 mg/kg) or the mao-a-selective inhibitor clorgyline (1.2 mg/kg) plus 5-htp. |
2008-01-14 |
2023-08-12 |
mouse |
| Amy Cecilia Sanders, Ali J Hussain, René Hen, Xiaoxi Zhuan. Chronic blockade or constitutive deletion of the serotonin transporter reduces operant responding for food reward. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 11. 2008-01-09. PMID:17356573. |
we report here the effects of chronic fluoxetine treatment and genetic deletion of the serotonin transporter (sert) on food reinforced behavior in three paradigms: the progressive ratio operant task, the concurrent choice operant task, and the pavlovian-to-instrumental transfer task. |
2008-01-09 |
2023-08-12 |
mouse |