| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Glauce Socorro de Barros Viana, Cecilia Coelho Xavier, Eduardo Mulato do Vale, Maria Janice Pereira Lopes, Viviane de Jesus Alves, Roberta de Oliveira Costa, Kelly Rose Tavares Neve. The monoaminergic pathways and inhibition of monoamine transporters interfere with the antidepressive-like behavior of ketamine. IBRO reports. vol 4. 2020-09-30. PMID:30135946. |
furthermore, reductions in sert immunoreactivities were observed in the striatum and hippocampus. |
2020-09-30 |
2023-08-13 |
mouse |
| Jun Zhao, Huiling Tian, Hongtao Song, Xu Wang, Tong Luo, Liya Ai, Yumin Fang, Jianghao Zhao, Saiyin Chao-Ke-Tu, Zhigang L. Effect of Electroacupuncture on Reuptake of Serotonin via miRNA-16 Expression in a Rat Model of Depression. Evidence-based complementary and alternative medicine : eCAM. vol 2019. 2020-09-30. PMID:31929820. |
after ea treatment for 4 weeks, behavioral changes and indices including 5-ht transporter (sert), 5-ht, and mirna-16 levels in the hippocampus and serum were examined. |
2020-09-30 |
2023-08-13 |
rat |
| Jun Zhao, Huiling Tian, Hongtao Song, Xu Wang, Tong Luo, Liya Ai, Yumin Fang, Jianghao Zhao, Saiyin Chao-Ke-Tu, Zhigang L. Effect of Electroacupuncture on Reuptake of Serotonin via miRNA-16 Expression in a Rat Model of Depression. Evidence-based complementary and alternative medicine : eCAM. vol 2019. 2020-09-30. PMID:31929820. |
the ea treatment significantly improved base levels of sucrose preference and exploratory behavior and significantly decreased sert protein and mrna expression in the hippocampus of depressed rats. |
2020-09-30 |
2023-08-13 |
rat |
| Per Plenge, Ara M Abramyan, Gunnar Sørensen, Arne Mørk, Pia Weikop, Ulrik Gether, Benny Bang-Andersen, Lei Shi, Claus J Lolan. The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter. Nature communications. vol 11. issue 1. 2020-07-17. PMID:32198394. |
the sert inhibition by lu af60097 is demonstrated by the potentiated imipramine binding and increased hippocampal serotonin level in rats. |
2020-07-17 |
2023-08-13 |
rat |
| Abdeslam Mouihate, Samah Kalakh, Rawan AlMutairi, Abdelrahman Alashqa. Prenatal Inflammation Dampens Neurogenesis and Enhances Serotonin Transporter Expression in the Hippocampus of Adult Female Rats. Medical principles and practice : international journal of the Kuwait University, Health Science Centre. vol 28. issue 4. 2020-06-30. PMID:30884483. |
therefore, we explored the impact of prenatal lps on neurogenesis, sert expression in the hippocampus, and anxiety-like behavior in female rats during prepubertal and adulthood stages. |
2020-06-30 |
2023-08-13 |
rat |
| Roberto Laureano-Melo, Janaina Sena de Souza, Rodrigo Rodrigues da Conceição, Josie Marcelle Lira Albuquerque, Nayana Coutinho Rodrigues, Bruno Guimarães Marinho, Emerson Lopes Olivares, Gisele Giannocco, Wellington da Silva Côrte. Prenatal thyroxine treatment promotes anxiolysis in male Swiss mice offspring. Hormones and behavior. vol 108. 2020-01-22. PMID:30576638. |
in the hippocampus, t4 offspring had a higher expression of tryptophan hydroxylase 2 (tph2), serotonin transporter (sert) and glutamate decarboxylase 67 (gad 67) in comparison to controls. |
2020-01-22 |
2023-08-13 |
mouse |
| Wei-Yu Zhu, Xia Feng, Jin Wang, Yu-Pan Lu, Xian-Zhe Dong, Ping Li. [Effect of Dingzhi Xiaowan on miR-16 expression and 5-HT reuptake]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 43. issue 17. 2019-07-29. PMID:30347920. |
firstly, a chronic unpredictable mild moderate stimulation (cums) combined with solitary rising depression rat model was established, the behavior changes were detected after different doses of dz (600, 300, 150 mg·kg⁻¹) given for 3 weeks, high performance liquid chromatography (hplc) was used to detect 5-ht level in hippocampal, pcr method was used to observe the effect of dz on the expression of sert mrna and mir-16 in hippocampus of cums rat. |
2019-07-29 |
2023-08-13 |
rat |
| Wei-Yu Zhu, Xia Feng, Jin Wang, Yu-Pan Lu, Xian-Zhe Dong, Ping Li. [Effect of Dingzhi Xiaowan on miR-16 expression and 5-HT reuptake]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 43. issue 17. 2019-07-29. PMID:30347920. |
the effects of dz (10, 100, 200, 500 mg·l⁻¹) on the expression of mir-16 and sert mrna in the cell model induced by mir-16 silencing and corticosterone or glutamate injury were observed in primary cultured hippocampal neurons of rats in vitro. |
2019-07-29 |
2023-08-13 |
rat |
| Wei-Yu Zhu, Xia Feng, Jin Wang, Yu-Pan Lu, Xian-Zhe Dong, Ping Li. [Effect of Dingzhi Xiaowan on miR-16 expression and 5-HT reuptake]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 43. issue 17. 2019-07-29. PMID:30347920. |
it was found that 300 mg·kg⁻¹ and 600 mg·kg⁻¹ dz could significantly improve the behavioral score of cums rats, increase the level of 5-ht in hippocampus, and increase the expression of mir-16 and decrease the expression of sert in the hippocampus of rats. |
2019-07-29 |
2023-08-13 |
rat |
| Wei-Yu Zhu, Xia Feng, Jin Wang, Yu-Pan Lu, Xian-Zhe Dong, Ping Li. [Effect of Dingzhi Xiaowan on miR-16 expression and 5-HT reuptake]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 43. issue 17. 2019-07-29. PMID:30347920. |
at the same time, in primary cultured hippocampal neurons, 100, 200, 500 mg·l⁻¹ of dz could significantly increase the expression level of mir-16 in mir-16 silencing and corticosterone or glutamate injury cell model, and decrease the expression level of sert significantly. |
2019-07-29 |
2023-08-13 |
rat |
| Eric Brown, Conor J Mc Veigh, Leilani Santos, Martina Gogarty, Heidi Kaastrup Müller, Betina Elfving, David J Brayden, Jana Haas. TNFα-dependent anhedonia and upregulation of hippocampal serotonin transporter activity in a mouse model of collagen-induced arthritis. Neuropharmacology. vol 137. 2019-02-20. PMID:29723540. |
behavioural symptoms are temporally correlated with a region-specific upregulation of sert activity in the hippocampus, which occurs at a post-translational level and is independent of sert trafficking. |
2019-02-20 |
2023-08-13 |
mouse |
| Matthew J Robson, Meagan A Quinlan, Kara Gross Margolis, Paula A Gajewski-Kurdziel, Jeremy Veenstra-VanderWeele, Michael D Gershon, D Martin Watterson, Randy D Blakel. p38α MAPK signaling drives pharmacologically reversible brain and gastrointestinal phenotypes in the SERT Ala56 mouse. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 43. 2018-12-11. PMID:30297392. |
mice expressing the most common of these variants (sert ala56) exhibit hyperserotonemia, a biomarker observed in asd subjects, as well as p38 mapk-dependent sert hyperphosphorylation, elevated hippocampal 5-ht clearance, hypersensitivity of cns 5-ht |
2018-12-11 |
2023-08-13 |
mouse |
| Wan-Hui Lin, Xiao-Feng Li, Ming-Xing Lin, Ying Zhou, Hua-Pin Huan. Novel insights into the effect of paroxetine administration in pilocarpine‑induced chronic epileptic rats. Molecular medicine reports. vol 16. issue 6. 2018-06-26. PMID:28983622. |
the aim of the present study was to investigate the role of paroxetine intervention in epilepsy, and its association with the expression of serotonin transporter (sert) and hippocampal apoptosis. |
2018-06-26 |
2023-08-13 |
rat |
| Wan-Hui Lin, Xiao-Feng Li, Ming-Xing Lin, Ying Zhou, Hua-Pin Huan. Novel insights into the effect of paroxetine administration in pilocarpine‑induced chronic epileptic rats. Molecular medicine reports. vol 16. issue 6. 2018-06-26. PMID:28983622. |
in the se group, sert expression was not altered in the raphe nucleus but was decreased in the hippocampus. |
2018-06-26 |
2023-08-13 |
rat |
| Wan-Hui Lin, Xiao-Feng Li, Ming-Xing Lin, Ying Zhou, Hua-Pin Huan. Novel insights into the effect of paroxetine administration in pilocarpine‑induced chronic epileptic rats. Molecular medicine reports. vol 16. issue 6. 2018-06-26. PMID:28983622. |
following paroxetine administration, sert expression was decreased in the raphe nucleus and increased in the hippocampus. |
2018-06-26 |
2023-08-13 |
rat |
| Cindy S Tao, Prateek Dhamija, Linda Booij, Janet L Menar. Adversity in early adolescence promotes an enduring anxious phenotype and increases serotonergic innervation of the infralimbic medial prefrontal cortex. Neuroscience. vol 364. 2018-06-08. PMID:28893650. |
after behavioural testing, we used immunohistochemistry for the 5-ht transporter (sert) to evaluate 5-ht innervation profiles in the medial prefrontal cortex (mpfc) and ventral hippocampus (vh). |
2018-06-08 |
2023-08-13 |
rat |
| Jia Zhang, Yan Fan, Muhammad U Raza, Yanqiang Zhan, Xiang-Dong Du, Paresh D Patel, Meng-Yang Zh. The regulation of corticosteroid receptors in response to chronic social defeat. Neurochemistry international. vol 108. 2018-04-13. PMID:28577990. |
as an extension of our previous studies, in situ hybridization and immunohistochemical staining demonstrated that csd regimen caused a notable increase of sert mrna levels in the dorsal raphe nucleus and increased sert immunoreactivities in ca1 and ca3 of the hippocampus, as well as those in the basolateral nuclei of the amygdala. |
2018-04-13 |
2023-08-13 |
Not clear |
| Jasmine I Caulfield, Michael J Caruso, Kerry C Michael, Rebecca A Bourne, Nicole R Chirichella, Laura C Klein, Timothy Craig, Robert H Bonneau, Avery August, Sonia A Cavigell. Peri-adolescent asthma symptoms cause adult anxiety-related behavior and neurobiological processes in mice. Behavioural brain research. vol 326. 2018-03-07. PMID:28284954. |
compared to controls, mice that experienced methacholine-induced labored breathing during adolescence displayed a ∼20% decrease in time on open arms of the elevated plus maze in early adulthood (p60), a ∼30% decrease in brainstem serotonin transporter (sert) mrna expression and a ∼50% increase in hippocampal serotonin receptor 1a (5htr1a) and corticotropin releasing hormone receptor 1 (crhr1) expression in adulthood (p75). |
2018-03-07 |
2023-08-13 |
mouse |
| Xiaoning Chen, Emilie I Petit, Kostantin Dobrenis, Ji Ying Sz. Spatiotemporal SERT expression in cortical map development. Neurochemistry international. vol 98. 2018-01-08. PMID:27282696. |
sert is transiently expressed in glutamatergic thalamic neurons projecting to sensory cortices and in pyramidal neurons in the prefrontal cortex (pfc) and hippocampus (hpc) during the period that lays down the basic functional neural circuits. |
2018-01-08 |
2023-08-13 |
mouse |
| Alex G Nackenoff, Alexandra B Moussa-Tooks, Austin M McMeekin, Jeremy Veenstra-VanderWeele, Randy D Blakel. Essential Contributions of Serotonin Transporter Inhibition to the Acute and Chronic Actions of Fluoxetine and Citalopram in the SERT Met172 Mouse. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 7. 2018-01-02. PMID:26514584. |
in addition, sert met172 mice are insensitive to chronic fluoxetine and citalopram administration in the novelty induced hypophagia test (nih) and fail to exhibit enhanced proliferation or survival of hippocampal stem cells. |
2018-01-02 |
2023-08-13 |
mouse |