| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kimberly Kirkpatrick, Andrew T Marshall, Aaron P Smith, Juraj Koci, Yoonseong Par. Individual differences in impulsive and risky choice: effects of environmental rearing conditions. Behavioural brain research. vol 269. 2015-01-15. PMID:24769268. |
hplc analyses were conducted to determine how monoamine concentrations within the prefrontal cortex (pfc) and nucleus accumbens (nac) related to behavior in different tasks. |
2015-01-15 |
2023-08-13 |
rat |
| Zai-Man Zhu, Tian-Miao Hua, Hong-Ming Zhou, Qun-Wan Pan, Jing Li, Min L. [A wireless telemetry study on the electrical activity in nucleus accumbens of heroin-induced place preference rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 30. issue 4. 2015-01-15. PMID:25330679. |
to analyze the electrical activity property changes in nucleus accumbens (nac) of heroin-induced conditioned place preference (cpp) rats during different stages of heroin dependence and to explore nac's roles in the formation of drug dependence. |
2015-01-15 |
2023-08-13 |
rat |
| Michael D Roberts, Ryan G Toedebusch, Kevin D Wells, Joseph M Company, Jacob D Brown, Clayton L Cruthirds, Alexander J Heese, Conan Zhu, George E Rottinghaus, Thomas E Childs, Frank W Boot. Nucleus accumbens neuronal maturation differences in young rats bred for low versus high voluntary running behaviour. The Journal of physiology. vol 592. issue 10. 2015-01-12. PMID:24665095. |
we compared the nucleus accumbens (nac) transcriptomes of generation 8 (g8), 34-day-old rats selectively bred for low (lvr) versus high voluntary running (hvr) behaviours in rats that never ran (lvr(non-run) and hvr(non-run)), as well as in rats after 6 days of voluntary wheel running (lvr(run) and hvr(run)). |
2015-01-12 |
2023-08-12 |
rat |
| Marloes S Oudijn, Jitschak G Storosum, Elise Nelis, Damiaan Deny. Is deep brain stimulation a treatment option for anorexia nervosa? BMC psychiatry. vol 13. 2015-01-06. PMID:24175936. |
given the overlap in symptomatology and neurocircuitry between reward-related disorders such as obsessive compulsive disorder (ocd) and an, and the established efficacy of accumbal dbs in ocd, we hypothesize that dbs of the nucleus accumbens (nac) and other areas associated with reward, e.g. |
2015-01-06 |
2023-08-12 |
Not clear |
| Morgan H James, Rikki K Quinn, Lin Kooi Ong, Emily M Levi, Janine L Charnley, Doug W Smith, Phillip W Dickson, Christopher V Daya. mTORC1 inhibition in the nucleus accumbens 'protects' against the expression of drug seeking and 'relapse' and is associated with reductions in GluA1 AMPAR and CAMKIIα levels. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 7. 2014-12-29. PMID:24469593. |
we found that withdrawal from cocaine self-administration increased indices of mtorc1 activity in the nucleus accumbens (nac). |
2014-12-29 |
2023-08-12 |
rat |
| Bahareh Pakpour, Shamseddin Ahmadi, Touraj Nayer-Nouri, Shahrbanoo Oryan, Mohammad Reza Zarrindas. Inhibitory avoidance memory deficit induced by scopolamine: interaction with glutamatergic system in the nucleus accumbens. Behavioural pharmacology. vol 21. issue 8. 2014-12-22. PMID:20926947. |
the possible involvement of n-methyl-d-aspartate (nmda) receptors of the nucleus accumbens (nac) in amnesia induced by scopolamine was investigated. |
2014-12-22 |
2023-08-12 |
rat |
| Hongyu Li, Qian Bu, Bo Chen, Xue Shao, Zhengtao Hu, Pengchi Deng, Lei Lv, Yi Deng, Ruiming Zhu, Yan Li, Baolai Zhang, Jing Hou, Changman Du, Qian Zhao, Dengqi Fu, Yinglan Zhao, Xiaobo Ce. Mechanisms of metabonomic for a gateway drug: nicotine priming enhances behavioral response to cocaine with modification in energy metabolism and neurotransmitter level. PloS one. vol 9. issue 1. 2014-12-22. PMID:24489831. |
(1)h nuclear magnetic resonance based on metabonomics was used to investigate metabolic profiles of the nucleus accumbens (nac) and striatum. |
2014-12-22 |
2023-08-12 |
mouse |
| Hannah M Cates, Mackenzie Thibault, Madeline Pfau, Elizabeth Heller, Andrew Eagle, Paula Gajewski, Rosemary Bagot, Christopher Colangelo, Thomas Abbott, Gabby Rudenko, Rachael Neve, Eric J Nestler, Alfred J Robiso. Threonine 149 phosphorylation enhances ΔFosB transcriptional activity to control psychomotor responses to cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 34. 2014-12-22. PMID:25143625. |
of particular interest is the transcription factor Δfosb, a truncated and stable fosb gene product whose expression in nucleus accumbens (nac), a key reward region, is induced by chronic exposure to virtually all drugs of abuse and regulates their psychomotor and rewarding effects. |
2014-12-22 |
2023-08-13 |
mouse |
| Munir G Kutlu, Dennis Burke, Susan Slade, Brandon J Hall, Jed E Rose, Edward D Levi. Role of insular cortex D₁ and D₂ dopamine receptors in nicotine self-administration in rats. Behavioural brain research. vol 256. 2014-12-18. PMID:23948214. |
the da projection from the ventral tegmental area to the nucleus accumbens (nac) has been shown to be a vital pathway for the primary reinforcement caused by taking a variety of abused drugs. |
2014-12-18 |
2023-08-12 |
rat |
| Alex S James, Jane Y Chen, Carlos Cepeda, Nitish Mittal, James David Jentsch, Michael S Levine, Christopher J Evans, Wendy Walwy. Opioid self-administration results in cell-type specific adaptations of striatal medium spiny neurons. Behavioural brain research. vol 256. 2014-12-18. PMID:23968589. |
thereafter, the electrophysiological properties of d1- and d2-msns in the shell region of the nucleus accumbens (nac) were assessed. |
2014-12-18 |
2023-08-12 |
mouse |
| Jeremy M Reimers, Jessica A Loweth, Marina E Wol. BDNF contributes to both rapid and homeostatic alterations in AMPA receptor surface expression in nucleus accumbens medium spiny neurons. The European journal of neuroscience. vol 39. issue 7. 2014-12-18. PMID:24712995. |
we recently showed that intracranial injection of bdnf into the rat nucleus accumbens (nac), a key region for cocaine addiction, rapidly increases α-amino-3-hyroxy-5-methyl-4-isoxazole-propionic acid receptor (ampar) surface expression. |
2014-12-18 |
2023-08-13 |
mouse |
| Yu-Jun Wang, Peng Huang, Julie A Blendy, Lee-Yuan Liu-Che. Brain region- and sex-specific alterations in DAMGO-stimulated [(35) S]GTPγS binding in mice with Oprm1 A112G. Addiction biology. vol 19. issue 3. 2014-12-16. PMID:22862850. |
in the nucleus accumbens (nac) core, female g/g mice displayed lower damgo-stimulated [(35) s]gtpγs binding than female a/a mice, which is consistent with the previously reported deficiency in morphine-induced conditioned place preference in female g/g mice. |
2014-12-16 |
2023-08-12 |
mouse |
| Anushka B P Fernando, Gonzalo P Urcelay, Adam C Mar, Tony A Dickinson, Trevor W Robbin. The role of the nucleus accumbens shell in the mediation of the reinforcing properties of a safety signal in free-operant avoidance: dopamine-dependent inhibitory effects of d-amphetamine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 6. 2014-12-15. PMID:24336447. |
this study investigated whether infusions of d-amphetamine in the nucleus accumbens (nac), previously shown to potentiate responding for appetitive conditioned reinforcers (crfs), also regulate avoidance responding for a ss. |
2014-12-15 |
2023-08-12 |
rat |
| Catherine M Claussen, Samuel L Chong, Nachum Dafn. Nucleus accumbens neuronal activity correlates to the animal's behavioral response to acute and chronic methylphenidate. Physiology & behavior. vol 129. 2014-12-15. PMID:24534179. |
acute and chronic methylphenidate (mpd) exposure was recorded simultaneously for the rat's locomotor activity and the nucleus accumbens (nac) neuronal activity. |
2014-12-15 |
2023-08-12 |
rat |
| Pei-Ching Chang, Sarah Lynn Pollema-Mays, Maria Virginia Centeno, Daniel Procissi, Massimo Contini, Alex Tomas Baria, Marco Martina, Apkar Vania Apkaria. Role of nucleus accumbens in neuropathic pain: linked multi-scale evidence in the rat transitioning to neuropathic pain. Pain. vol 155. issue 6. 2014-12-15. PMID:24607959. |
despite recent evidence implicating the nucleus accumbens (nac) as causally involved in the transition to chronic pain in humans, underlying mechanisms of this involvement remain entirely unknown. |
2014-12-15 |
2023-08-12 |
rat |
| X Jiang, J J Zhang, M Y Wang, N Su. Differential muscarinic modulation of synaptic transmission in dorsal and ventral regions of the rat nucleus accumbens core. Physiological research. vol 63. issue 1. 2014-12-08. PMID:24182333. |
the nucleus accumbens (nac) core is critical in the control of motivated behaviors. |
2014-12-08 |
2023-08-12 |
rat |
| Jonathan A Sugam, Michael P Saddoris, Regina M Carell. Nucleus accumbens neurons track behavioral preferences and reward outcomes during risky decision making. Biological psychiatry. vol 75. issue 10. 2014-12-03. PMID:24143880. |
the nucleus accumbens (nac) has been shown to be critical for this processing and is necessary for appropriate risk-based decision-making behavior. |
2014-12-03 |
2023-08-12 |
Not clear |
| Giuseppe Mocci, Laura Jiménez-Sánchez, Albert Adell, Roser Cortés, Francesc Artiga. Expression of 5-HT2A receptors in prefrontal cortex pyramidal neurons projecting to nucleus accumbens. Potential relevance for atypical antipsychotic action. Neuropharmacology. vol 79. 2014-12-03. PMID:24211653. |
classical antipsychotic drugs modulate information processing in cortico-limbic circuits via dopamine d2 receptor blockade in nucleus accumbens (nac) whereas atypical antipsychotic drugs preferentially target cortical serotonin (5-ht) receptors. |
2014-12-03 |
2023-08-12 |
rat |
| Alessia Salamone, Stefania Zappettini, Massimo Grilli, Guendalina Olivero, Paula Agostinho, Angelo R Tomé, Jiayang Chen, Anna Pittaluga, Rodrigo A Cunha, Mario March. Prolonged nicotine exposure down-regulates presynaptic NMDA receptors in dopaminergic terminals of the rat nucleus accumbens. Neuropharmacology. vol 79. 2014-12-03. PMID:24373903. |
the presynaptic control of dopamine release in the nucleus accumbens (nac) by glutamate and acetylcholine has a profound impact on reward signaling. |
2014-12-03 |
2023-08-12 |
rat |
| Kimberly A Leite-Morris, Kendra L Kobrin, Marsha D Guy, Angela J Young, Stephen C Heinrichs, Gary B Kapla. Extinction of opiate reward reduces dendritic arborization and c-Fos expression in the nucleus accumbens core. Behavioural brain research. vol 263. 2014-12-03. PMID:24406724. |
changes in dendritic morphology and spine quantity were examined in the nucleus accumbens (nac) core and shell neurons. |
2014-12-03 |
2023-08-12 |
mouse |