All Relations between nac and nucleus accumbens

Publication Sentence Publish Date Extraction Date Species
Jordan T Yorgason, Mark J Ferris, Scott C Steffensen, Sara R Jone. Frequency-dependent effects of ethanol on dopamine release in the nucleus accumbens. Alcoholism, clinical and experimental research. vol 38. issue 2. 2014-09-29. PMID:24117706. ethanol (etoh) is known to have excitatory effects on dopamine (da) release, with moderate-to-high doses (0.5 to 2.5 g/kg) of acute etoh enhancing da neuron firing rates in the ventral tegmental area (vta) and da levels in the nucleus accumbens (nac). 2014-09-29 2023-08-12 Not clear
N Zhao, Y Chen, J Zhu, L Wang, G Cao, Y Dang, C Yan, J Wang, T Che. Levo-tetrahydropalmatine attenuates the development and expression of methamphetamine-induced locomotor sensitization and the accompanying activation of ERK in the nucleus accumbens and caudate putamen in mice. Neuroscience. vol 258. 2014-09-29. PMID:24269936. therefore, the current study aims to examine the roles of l-thp in the development and expression of meth-induced locomotor sensitization as well as the accompanying extracellular-regulated kinase (erk) activation in the nucleus accumbens (nac), caudate putamen (cpu) and prefrontal cortex (pfc) in mice. 2014-09-29 2023-08-12 mouse
Jeffrey L Barr, Gina L Forster, Ellen M Unterwal. Repeated cocaine enhances ventral hippocampal-stimulated dopamine efflux in the nucleus accumbens and alters ventral hippocampal NMDA receptor subunit expression. Journal of neurochemistry. vol 130. issue 4. 2014-09-29. PMID:24832868. a behaviorally sensitizing regimen of cocaine (20 mg/kg, ip 7 days) also sensitized ventral hippocampus (hipp)-mediated dopaminergic transmission within the nucleus accumbens (nac) to nmda stimulation (bolts). 2014-09-29 2023-08-13 rat
J L Harenza, P P Muldoon, M De Biasi, M I Damaj, M F Mile. Genetic variation within the Chrna7 gene modulates nicotine reward-like phenotypes in mice. Genes, brain, and behavior. vol 13. issue 2. 2014-09-25. PMID:24289814. to identify molecular events downstream of chrna7 that may modulate nicotine preference, we performed microarray analysis of α7 knock-out (ko) and wild-type (wt) nucleus accumbens (nac) tissue, followed by confirmation with quantitative polymerase chain reaction (pcr) and immunoblotting. 2014-09-25 2023-08-12 mouse
Xuekun Ding, Yanhua Qiao, Chengji Piao, Xigeng Zheng, Zhengkui Liu, Jing Lian. N-methyl-D-aspartate receptor-mediated glutamate transmission in nucleus accumbens plays a more important role than that in dorsal striatum in cognitive flexibility. Frontiers in behavioral neuroscience. vol 8. 2014-09-24. PMID:25249952. the blockade of nmdars in the nucleus accumbens (nac) core by ap5 impaired set-shifting ability by causing a failure to modify prior learning. 2014-09-24 2023-08-13 rat
Kazuya Toriumi, Mizuki Kondo, Taku Nagai, Ryota Hashimoto, Kazutaka Ohi, Ziyu Song, Junko Tanaka, Akihiro Mouri, Takenao Koseki, Hidenaga Yamamori, Yoko Furukawa-Hibi, Takayoshi Mamiya, Takeshi Fukushima, Masatoshi Takeda, Atsumi Nitta, Kiyofumi Yamada, Toshitaka Nabeshim. Deletion of SHATI/NAT8L increases dopamine D1 receptor on the cell surface in the nucleus accumbens, accelerating methamphetamine dependence. The international journal of neuropsychopharmacology. vol 17. issue 3. 2014-09-17. PMID:24246274. shati/nat8l attenuates the meth-induced increase in dopamine overflow in the nucleus accumbens (nac) by promoting plasmalemmal and vesicular dopamine uptake. 2014-09-17 2023-08-12 mouse
Yafang Zhang, Elizabeth J Crofton, Dingge Li, Mary Kay Lobo, Xiuzhen Fan, Eric J Nestler, Thomas A Gree. Overexpression of DeltaFosB in nucleus accumbens mimics the protective addiction phenotype, but not the protective depression phenotype of environmental enrichment. Frontiers in behavioral neuroscience. vol 8. 2014-09-15. PMID:25221490. chronic stress or chronic cocaine treatment each elevates Δfosb protein levels in the nucleus accumbens (nac) of ic rats, but not of ec rats due to an already elevated basal accumulation of Δfosb seen under ec conditions. 2014-09-15 2023-08-13 rat
Michael D Leitl, Sara Onvani, M Scott Bowers, Kejun Cheng, Kenner C Rice, William A Carlezon, Matthew L Banks, S Stevens Negu. Pain-related depression of the mesolimbic dopamine system in rats: expression, blockade by analgesics, and role of endogenous κ-opioids. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 3. 2014-09-10. PMID:24008352. adult male sprague-dawley rats were implanted with electrodes targeting the medial forebrain bundle (for behavior studies of intracranial self-stimulation (icss)) or with cannulae for microdialysis measures of nucleus accumbens dopamine (nac da). 2014-09-10 2023-08-12 rat
William C Griffin, Harold L Haun, Callan L Hazelbaker, Vorani S Ramachandra, Howard C Becke. Increased extracellular glutamate in the nucleus accumbens promotes excessive ethanol drinking in ethanol dependent mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 3. 2014-09-10. PMID:24067300. using a well-established model of ethanol dependence and relapse, this study examined adaptations in glutamatergic transmission in the nucleus accumbens (nac) and their role in regulating voluntary ethanol drinking. 2014-09-10 2023-08-12 mouse
Kai-jun Yang, Hao Long, Ya-wei Yuan, Song-tao Qi, Bo-tao Xu, Ke-wan Wang, Ye Son. Stereotactic neurosurgical technique and electrophysiological study in ablating the ventromedial shell of the nucleus accumbens. Stereotactic and functional neurosurgery. vol 92. issue 1. 2014-09-08. PMID:24217022. to describe in as much detail as possible the method for ablating the ventromedial shell of the nucleus accumbens (nac) and investigate the efficacy and safety of the ablation treatment. 2014-09-08 2023-08-12 Not clear
M M Kraus, H Prast, A Philipp. Influence of the hippocampus on amino acid utilizing and cholinergic neurons within the nucleus accumbens is promoted by histamine via H₁ receptors. British journal of pharmacology. vol 170. issue 1. 2014-09-05. PMID:23594121. the influence of the neurotransmitter histamine on spontaneous and stimulation-evoked release of glutamate, aspartate, gaba and ach in the nucleus accumbens (nac) was investigated in vivo. 2014-09-05 2023-08-12 Not clear
M M Kraus, H Prast, A Philipp. Facilitation of short-term memory by histaminergic neurons in the nucleus accumbens is independent of cholinergic and glutamatergic transmission. British journal of pharmacology. vol 170. issue 1. 2014-09-05. PMID:23750549. here, we have investigated whether learning and/or short-term memory was associated with release of ach and glutamate in the rat nucleus accumbens (nac). 2014-09-05 2023-08-12 rat
Grewo Lim, Hyangin Kim, Michael F McCabe, Chiu-Wen Chou, Shuxing Wang, Lucy L Chen, John J A Marota, Anne Blood, Hans C Breiter, Jianren Ma. A leptin-mediated central mechanism in analgesia-enhanced opioid reward in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 29. 2014-09-05. PMID:25031415. at the cellular level, administration of morphine activated a cascade of leptin expression, glial activation, and dopamine receptor upregulation in the nucleus accumbens (nac), while administration of ibuprofen decreased glial activation with no effect on leptin expression in the nac. 2014-09-05 2023-08-13 mouse
A M Falco, C G McDonald, S E Bachus, R F Smit. Developmental alterations in locomotor and anxiety-like behavior as a function of D1 and D2 mRNA expression. Behavioural brain research. vol 260. 2014-09-02. PMID:24239691. research suggests that these behavioral effects may be due in part to dopamine (da) receptors d1 and d2 in the mesolimbic system, specifically the nucleus accumbens (nac). 2014-09-02 2023-08-12 rat
Amy M Gancarz-Kausch, Gabrielle L Schroeder, Clarisse Panganiban, Danielle Adank, Monica S Humby, Michael A Kausch, Stewart D Clark, David M Diet. Transforming growth factor beta receptor 1 is increased following abstinence from cocaine self-administration, but not cocaine sensitization. PloS one. vol 8. issue 12. 2014-08-31. PMID:24386286. here, we investigated transforming growth factor-beta type i receptor (tgf-β r1) expression in the nucleus accumbens (nac) following periods of withdrawal from cocaine self-administration (sa) and a sensitizing regimen of non-contingent cocaine. 2014-08-31 2023-08-12 rat
Lucia Caffino, Chiara Cassina, Giuseppe Giannotti, Alessandro Orrù, Federico Moro, Angelo Di Clemente, Giorgio Racagni, Fabio Fumagalli, Luigi Cerv. Short-term abstinence from cocaine self-administration, but not passive cocaine infusion, elevates αCaMKII autophosphorylation in the rat nucleus accumbens and medial prefrontal cortex. The international journal of neuropsychopharmacology. vol 17. issue 2. 2014-08-26. PMID:23953174. increased αcamkii autophosphorylation in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc), but not dorsolateral striatum (dls), was found 24 h, but not immediately, after the last cocaine self-administration session. 2014-08-26 2023-08-12 rat
Balakrishnan Selvakumar, Peter W Campbell, Mike Milovanovic, Diana J Park, Anthony R West, Solomon H Snyder, Marina E Wol. AMPA receptor upregulation in the nucleus accumbens shell of cocaine-sensitized rats depends upon S-nitrosylation of stargazin. Neuropharmacology. vol 77. 2014-08-26. PMID:24035918. behavioral sensitization to cocaine is associated with increased ampa receptor (ampar) surface expression in the nucleus accumbens (nac). 2014-08-26 2023-08-12 rat
Katharine L Campi, Gian D Greenberg, Amita Kapoor, Toni E Ziegler, Brian C Traino. Sex differences in effects of dopamine D1 receptors on social withdrawal. Neuropharmacology. vol 77. 2014-08-26. PMID:24120838. dopamine signaling in the nucleus accumbens (nac) plays a critical role in the regulation of motivational states. 2014-08-26 2023-08-12 mouse
Jamie D Roitman, Amy L Loriau. Nucleus accumbens responses differentiate execution and restraint in reward-directed behavior. Journal of neurophysiology. vol 111. issue 2. 2014-08-26. PMID:24174652. the nucleus accumbens (nac) is ideally situated to integrate multiple cognitive and affective inputs to bias action via outputs through the basal ganglia. 2014-08-26 2023-08-12 rat
Debra A Cooper, Heather L Kimmel, Daniel F Manvich, Karl T Schmidt, David Weinshenker, Leonard L Howel. Effects of pharmacologic dopamine β-hydroxylase inhibition on cocaine-induced reinstatement and dopamine neurochemistry in squirrel monkeys. The Journal of pharmacology and experimental therapeutics. vol 350. issue 1. 2014-08-26. PMID:24817036. to investigate the neurochemical mechanisms underlying the behavioral results, the effects of dbh inhibition on extracellular da were analyzed in the nucleus accumbens (nac) using in vivo microdialysis in squirrel monkeys. 2014-08-26 2023-08-13 rat