| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Soon Young Jang, Aeree Kim, Jin Kyoung Kim, Chungyel Kim, Youl-Hee Cho, Jong-Ho Kim, Chul Hwan Kim, Ji-Yun Le. Metformin inhibits tumor cell migration via down-regulation of MMP9 in tamoxifen-resistant breast cancer cells. Anticancer research. vol 34. issue 8. 2014-11-11. PMID:25075039. |
this inhibition was correlated with the modulation of matrix metalloproteinase-9 (mmp9) via the suppression of its expression and proteolytic activity. |
2014-11-11 |
2023-08-13 |
human |
| H Li, F Huang, L Fan, Y Jiang, X Wang, J Li, Q Wang, H Pan, J Sun, X Cao, X Wan. Phosphatidylethanolamine-binding protein 4 is associated with breast cancer metastasis through Src-mediated Akt tyrosine phosphorylation. Oncogene. vol 33. issue 37. 2014-11-10. PMID:24276246. |
further investigation showed that hpebp4 promoted the expression or activity of the metastasis-related proteinases mmp (matrix metalloproteinase) 2, mmp9 and mmp13. |
2014-11-10 |
2023-08-12 |
mouse |
| Heiani Touaitahuata, Gaelle Cres, Sylvain de Rossi, Virginie Vives, Anne Blang. The mineral dissolution function of osteoclasts is dispensable for hypertrophic cartilage degradation during long bone development and growth. Developmental biology. vol 393. issue 1. 2014-11-06. PMID:24992711. |
in vitro, we show that dock5(-/-) osteoclasts do present acidic compartments at the ventral plasma membrane and produce normal amounts of active mmp9, trap and ctsk for matrix protein degradation but they are unable to solubilize minerals. |
2014-11-06 |
2023-08-13 |
mouse |
| Shu-Lin Guo, Cheng-Ta Han, Jiun-Lung Jung, Wei-Jung Chen, John Jian-Feng Mei, Hoong-Chien Lee, Yu-Che Chen. Cystatin C in cerebrospinal fluid is upregulated in elderly patients with chronic osteoarthritis pain and modulated through matrix metalloproteinase 9-specific pathway. The Clinical journal of pain. vol 30. issue 4. 2014-11-04. PMID:23887333. |
this study evaluated the effects of intrathecal cysc content from chronic pain caused by osteoarthritis (oa) and the novel relationship with matrix metalloproteinases 2 and 9 (mmp2 and mmp9) in csf. |
2014-11-04 |
2023-08-12 |
Not clear |
| Hiroaki Inaba, Hideyuki Sugita, Masae Kuboniwa, Soichi Iwai, Masakazu Hamada, Takeshi Noda, Ichijiro Morisaki, Richard J Lamont, Atsuo Aman. Porphyromonas gingivalis promotes invasion of oral squamous cell carcinoma through induction of proMMP9 and its activation. Cellular microbiology. vol 16. issue 1. 2014-11-04. PMID:23991831. |
furthermore, matrix metalloproteinase 9 (mmp9) is implicated in the invasion and metastasis of tumour cells. |
2014-11-04 |
2023-08-12 |
Not clear |
| Mathew B Cox, Nikola A Bowden, Rodney J Scott, Jeannette Lechner-Scot. Common genetic variants in the plasminogen activation pathway are not associated with multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). vol 20. issue 4. 2014-10-31. PMID:23897640. |
matrix metalloproteinase 9 (mmp9) is involved in multiple sclerosis (ms) aetiology. |
2014-10-31 |
2023-08-12 |
Not clear |
| Nino Muradashvili, Reeta Tyagi, Naira Metreveli, Suresh C Tyagi, David Lominadz. Ablation of MMP9 gene ameliorates paracellular permeability and fibrinogen-amyloid beta complex formation during hyperhomocysteinemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 34. issue 9. 2014-10-31. PMID:24865997. |
we hypothesized that hhcy-enhanced cerebrovascular permeability occurs via activation of matrix metalloproteinase-9 (mmp9) and leads to an increased formation of fibrinogen-β-amyloid (fg-aβ) complex. |
2014-10-31 |
2023-08-13 |
mouse |
| So Motoyoshi, Yasuhiko Yamamoto, Seiichi Munesue, Hirobumi Igawa, Ai Harashima, Hidehito Saito, Dong Han, Takuo Watanabe, Hiroshi Sato, Hiroshi Yamamot. cAMP ameliorates inflammation by modulation of macrophage receptor for advanced glycation end-products. The Biochemical journal. vol 463. issue 1. 2014-10-31. PMID:24995813. |
this shedding is the result of ectodomain cleavage of mrage (membrane-bound rage) by mmp9 (matrix metalloproteinase 9). |
2014-10-31 |
2023-08-13 |
mouse |
| C Bearzi, C Gargioli, D Baci, O Fortunato, K Shapira-Schweitzer, O Kossover, M V G Latronico, D Seliktar, G Condorelli, R Rizz. PlGF-MMP9-engineered iPS cells supported on a PEG-fibrinogen hydrogel scaffold possess an enhanced capacity to repair damaged myocardium. Cell death & disease. vol 5. 2014-10-21. PMID:24525729. |
cell-based regenerative therapies are significantly improved by engineering allografts to express factors that increase vascularization and engraftment, such as placental growth factor (plgf) and matrix metalloproteinase 9 (mmp9). |
2014-10-21 |
2023-08-12 |
mouse |
| Wei Zhang, Guanjun Tu, Chen Lv, Jun Long, Lin Cong, Yaxin Ha. Matrix metalloproteinase-9 is up-regulated by CCL19/CCR7 interaction via PI3K/Akt pathway and is involved in CCL19-driven BMSCs migration. Biochemical and biophysical research communications. vol 451. issue 2. 2014-10-21. PMID:25086360. |
the aim of this study was to determine the possible interaction between ccl19-induced conditions and matrix metalloproteinases-9 (mmp9) expression in bmscs. |
2014-10-21 |
2023-08-13 |
Not clear |
| Christoph Wille, Conny Köhler, Milena Armacki, Arsia Jamali, Ulrike Gössele, Klaus Pfizenmaier, Thomas Seufferlein, Tim Eisele. Protein kinase D2 induces invasion of pancreatic cancer cells by regulating matrix metalloproteinases. Molecular biology of the cell. vol 25. issue 3. 2014-10-17. PMID:24336522. |
pkd2 enhances invasion in three-dimensional extracellular matrix (3d-ecm) cultures by stimulating expression and secretion of matrix metalloproteinases 7 and 9 (mmp7/9), by which mmp7 is likely to act upstream of mmp9. |
2014-10-17 |
2023-08-12 |
Not clear |
| Begum Alural, Gizem Ayna Duran, Kemal Ugur Tufekci, Jens Allmer, Zeynep Onkal, Dogan Tunali, Kursad Genc, Sermin Gen. EPO Mediates Neurotrophic, Neuroprotective, Anti-Oxidant, and Anti-Apoptotic Effects via Downregulation of miR-451 and miR-885-5p in SH-SY5Y Neuron-Like Cells. Frontiers in immunology. vol 5. 2014-10-17. PMID:25324845. |
low expression of mirnas in sh-sy5y was correlated with high expression of their target genes, vascular endothelial growth factor a, matrix metallo peptidase 9 (mmp9), cyclin-dependent kinase 2 (cdk2), erythropoietin receptor, mini chromosome maintenance complex 5 (mcm5), b-cell lymphoma 2 (bcl2), and galanin (gal). |
2014-10-17 |
2023-08-13 |
Not clear |
| Jun Pei, Yuqing Lou, Runbo Zhong, Baohui Ha. MMP9 activation triggered by epidermal growth factor induced FoxO1 nuclear exclusion in non-small cell lung cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 35. issue 7. 2014-10-06. PMID:24705809. |
the molecular mechanism underlying activation of matrix metallopeptidase 9 (mmp9) in non-small cell lung cancer (nsclc) cells, which controls cancer invasiveness and metastasis, remains elusive. |
2014-10-06 |
2023-08-13 |
human |
| Hongtao Song, Zhennan Tian, Yu Qin, Guodong Yao, Songbin Fu, Jingshu Gen. Astrocyte elevated gene-1 activates MMP9 to increase invasiveness of colorectal cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 35. issue 7. 2014-10-06. PMID:24705862. |
transcription, protein levels, and secretion of matrix metalloproteinase 9 (mmp9), all increased by aeg-1 overexpression in crc cells, and all decreased by aeg-1 inhibition. |
2014-10-06 |
2023-08-13 |
human |
| Jin Chen, Qin Huang, Feng Wan. Inhibition of FoxO1 nuclear exclusion prevents metastasis of glioblastoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 35. issue 7. 2014-10-06. PMID:24771221. |
although previous studies have demonstrated that expression of matrix metalloproteinase-9 (mmp9) in glioblastoma promotes cancer metastasis, the upstream molecular signaling cascades that control activation of mmp9 remain largely unknown. |
2014-10-06 |
2023-08-13 |
human |
| Pauli Puolakkainen, Aino Koski, Sanna Vainionpää, Zhanlong Shen, Heikki Repo, Esko Kemppainen, Harri Mustonen, Hanna Seppäne. Anti-inflammatory macrophages activate invasion in pancreatic adenocarcinoma by increasing the MMP9 and ADAM8 expression. Medical oncology (Northwood, London, England). vol 31. issue 3. 2014-09-30. PMID:24526468. |
the aim of this study was to examine the role of the inflammatory cells in the invasion of pancreatic cancer cells, focusing on the involvement of a disintegrin and metalloproteinase 8 (adam8) and matrix metalloproteinase 9 (mmp9) proteins. |
2014-09-30 |
2023-08-12 |
Not clear |
| Pauli Puolakkainen, Aino Koski, Sanna Vainionpää, Zhanlong Shen, Heikki Repo, Esko Kemppainen, Harri Mustonen, Hanna Seppäne. Anti-inflammatory macrophages activate invasion in pancreatic adenocarcinoma by increasing the MMP9 and ADAM8 expression. Medical oncology (Northwood, London, England). vol 31. issue 3. 2014-09-30. PMID:24526468. |
anti-inflammatory macrophages increase pancreatic cancer cell migration rate in basement membrane matrix by inducing adam8 and mmp9 expression in cancer cells, thereby possibly enhancing the invasiveness of cancer. |
2014-09-30 |
2023-08-12 |
Not clear |
| Martha Lappa. NOD1 expression is increased in the adipose tissue of women with gestational diabetes. The Journal of endocrinology. vol 222. issue 1. 2014-09-28. PMID:24829218. |
in both omental and subcutaneous adipose tissues from ngt and gdm women, the nod1 ligand g-d-glutamyl-meso-diaminopimelic acid (ie-dap) significantly induced the expression and secretion of the pro-inflammatory cytokine interleukin 6 (il6) and chemokine il8; cox2 (ptgs2) gene expression and subsequent prostaglandin production; the expression and secretion of the extracellular matrix remodelling enzyme matrix metalloproteinase 9 (mmp9) and the gene expression and secretion of the adhesion molecules icam1 and vcam1. |
2014-09-28 |
2023-08-13 |
Not clear |
| Jing Wang, Jia Zhou, Ning Zhang, Xiaoling Zhang, Qingfeng L. A heterocyclic molecule kartogenin induces collagen synthesis of human dermal fibroblasts by activating the smad4/smad5 pathway. Biochemical and biophysical research communications. vol 450. issue 1. 2014-09-21. PMID:24928394. |
results showed that without obvious influence on fibroblasts' apoptosis and viability, kgn stimulated type-i collagen synthesis of fibroblasts at the mrna and protein levels in a time-dependent manner, but kgn did not induce expression of α-skeletal muscle actin (α-sma) or matrix metallopeptidase1 (mmp1), mmp9 in vitro. |
2014-09-21 |
2023-08-13 |
mouse |
| Z N Zhou, V P Sharma, B T Beaty, M Roh-Johnson, E A Peterson, N Van Rooijen, P A Kenny, H S Wiley, J S Condeelis, J E Segal. Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in vivo. Oncogene. vol 33. issue 29. 2014-09-19. PMID:24013225. |
hbegf expression also resulted in enhanced invadopodium function via upregulation of matrix metalloprotease 2 (mmp2) and mmp9 expression levels. |
2014-09-19 |
2023-08-12 |
Not clear |