| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yali Wang, Jia Jia, Guizhen Ao, Lifang Hu, Hui Liu, Yunqi Xiao, Huaping Du, Nabil J Alkayed, Chun-Feng Liu, Jian Chen. Hydrogen sulfide protects blood-brain barrier integrity following cerebral ischemia. Journal of neurochemistry. vol 129. issue 5. 2014-07-10. PMID:24673410. |
we also investigated if adt protected bbb integrity by suppressing post-ischemic inflammation-induced matrix metalloproteimase-9 (mmp9) and nicotinamide adenine dinucleotide phosphate (nadph) oxidase (nox). |
2014-07-10 |
2023-08-12 |
mouse |
| A V Shevchenko, V I Konenkov, V F Prokof'ev, E A Pokushalo. [Analysis of genotype combinations at the polymorphic points of the promoter regions of the genes of three matrix metalloproteinases and the gene of vascular endothelial growth factor (VEGF) in patients with history of acute myocardial infarction]. Terapevticheskii arkhiv. vol 86. issue 4. 2014-06-26. PMID:24864463. |
to analyze the association of the promoter polymorphism of the genes of the matrix metalloproteinases (mmp) mmp2 (-1306), mmp3 (-1171), and mmp9 (-1562) and two vascular endothelial growth factor (vegf) gene regulatory regions (-2578, +936) with the development of myocardial infarction (mi). |
2014-06-26 |
2023-08-13 |
Not clear |
| Jin Dai, Ning Zhang, Jinhui Wang, Minhu Chen, Jie Che. Gastrokine-2 is downregulated in gastric cancer and its restoration suppresses gastric tumorigenesis and cancer metastasis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 35. issue 5. 2014-06-24. PMID:24408014. |
overexpression of gkn2 also reduced the expression levels of cylind1, cycline1, and matrix metalloproteinase 9 (mmp9), which were correlated with proliferation and metastasis of cancer cells. |
2014-06-24 |
2023-08-12 |
mouse |
| Zhi-hua Yu, Te Liu, Yan-hui Zhao, Yong-yi Huang, Yong-tao Ga. Cisplatin targets the stromal cell-derived factor-1-CXC chemokine receptor type 4 axis to suppress metastasis and invasion of ovarian cancer-initiating cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 35. issue 5. 2014-06-24. PMID:24408020. |
the expression levels of stromal cell-derived factor (sdf)-1, cxcr4, matrix metalloproteinase (mmp) 2, and mmp9 mrna and protein levels were significantly reduced in cddp-treated cells compared to untreated ovarian cics. |
2014-06-24 |
2023-08-12 |
human |
| Vladimir Riabov, Alexandru Gudima, Nan Wang, Amanda Mickley, Alexander Orekhov, Julia Kzhyshkowsk. Role of tumor associated macrophages in tumor angiogenesis and lymphangiogenesis. Frontiers in physiology. vol 5. 2014-06-24. PMID:24634660. |
elevated expression of mmp9 by tam mediates extracellular matrix (ecm) degradation and the release of bioactive vegfa. |
2014-06-24 |
2023-08-12 |
human |
| Dong Chen, Daogong Zhang, Lei Xu, Yuechen Han, Haibo Wan. The alterations of matrix metalloproteinase-9 in mouse brainstem during herpes simplex virus type 1-induced facial palsy. Journal of molecular neuroscience : MN. vol 51. issue 3. 2014-06-23. PMID:23817985. |
the aim of this study is to explore the changes of matrix metalloproteinase-9 (mmp9) in the mouse brainstem during the development of facial paralysis induced by herpes simplex virus type 1 (hsv-1) and the inhibitory effect of methylprednisolone sodium succinate (mpss) on mmp9 expression. |
2014-06-23 |
2023-08-12 |
mouse |
| Shunzeng Lv, Juan Qin, Ruiyang Yi, Melody Coreman, Ranran Shi, Huihui Kang, Chengjun Ya. CrkL efficiently mediates cell proliferation, migration, and invasion induced by TGF-β pathway in glioblastoma. Journal of molecular neuroscience : MN. vol 51. issue 3. 2014-06-23. PMID:23959425. |
erk1/2, smad2, and matrix metalloproteinase 9 (mmp9) were also analyzed by western blot. |
2014-06-23 |
2023-08-12 |
Not clear |
| Peng-Cheng Chen, Ji-Run Peng, Lei Huang, Wen-Xia Li, Wen-Zhen Wang, Zhu-Qing-Qing Cui, Hui Han, Lei Gong, Da-Peng Xiang, Shi-Shi Qiao, Xin Yu, Yu-Hua Wei, Li-Ping Ma, Na Li, Ji-Ye Zhu, Xi-Sheng Len. Overexpression of human telomerase reverse transcriptase promotes the motility and invasiveness of HepG2 cells in vitro. Oncology reports. vol 30. issue 3. 2014-06-12. PMID:23799592. |
further analysis suggested that enhanced invasiveness and metastasis may act through corresponding upregulation of mrna and protein expression of matrix metalloproteinase 9 (mmp9) and ras homolog gene family member c (rhoc). |
2014-06-12 |
2023-08-12 |
human |
| P K Kamat, A Kalani, S Givvimani, P B Sathnur, S C Tyagi, N Tyag. Hydrogen sulfide attenuates neurodegeneration and neurovascular dysfunction induced by intracerebral-administered homocysteine in mice. Neuroscience. vol 252. 2014-06-11. PMID:23912038. |
the increased expression of matrix metalloproteinase (mmp) mmp9, mmp2 and decreased expression of tissue inhibitor of metalloproteinase (timp) timp-1, timp-2, tight junction proteins (zonula occulden 1) in hcy-treated group indicate neurovascular remodeling. |
2014-06-11 |
2023-08-12 |
mouse |
| Boleslaw K Winiarski, Nichola Cope, Mary Alexander, Luke C Pilling, Sophie Warren, Nigel Acheson, Nicholas J Gutowski, Jacqueline L Whatmor. Clinical Relevance of Increased Endothelial and Mesothelial Expression of Proangiogenic Proteases and VEGFA in the Omentum of Patients with Metastatic Ovarian High-Grade Serous Carcinoma. Translational oncology. vol 7. issue 2. 2014-06-10. PMID:24913675. |
we investigated the expression of angiogenic proteases [cathepsin d (cd), cathepsin l (cl), and matrix metalloproteinase 2 (mmp2) and mmp9] and vascular endothelial growth factor a (vegfa) in the mesothelium and endothelium of omentum from patients with eoc with omental metastases and control patients with benign ovarian tumors. |
2014-06-10 |
2023-08-13 |
Not clear |
| Lucas González-Herrera, Aurora Valenzuela, Juan A Marchal, José A Lorente, Enrique Villanuev. Studies on RNA integrity and gene expression in human myocardial tissue, pericardial fluid and blood, and its postmortem stability. Forensic science international. vol 232. issue 1-3. 2014-06-05. PMID:24053884. |
gene expression of cardiac troponin i (tnni3), myosin light chain 3 (myl3), matrix metalloprotease 9 (mmp9), transforming growth factor beta 1 (tgfb1), and vascular endothelial growth factor a (vegfa) in myocardial zones and body fluids were subsequently studied by real-time quantitative pcr. |
2014-06-05 |
2023-08-12 |
human |
| Anindita Dutta, Jing Li, Huimin Lu, Jacqueline Akech, Jitesh Pratap, Tao Wang, Brad J Zerlanko, Thomas J FitzGerald, Zhong Jiang, Ruth Birbe, John Wixted, Shelia M Violette, Janet L Stein, Gary S Stein, Jane B Lian, Lucia R Languin. Integrin αvβ6 promotes an osteolytic program in cancer cells by upregulating MMP2. Cancer research. vol 74. issue 5. 2014-06-03. PMID:24385215. |
we show for the first time that αvβ6 selectively induces matrix metalloproteinase 2 (mmp2) in vitro in multiple prostate cancer cells and promotes osteolysis in vivo in an immunodeficient mouse model of bone metastasis through upregulation of mmp2, but not mmp9. |
2014-06-03 |
2023-08-12 |
mouse |
| Shou-Tang Wang, Ying-Jie Gao, Cui-Cui Duan, Dang-Dang Li, Xue-Chao Tian, Qiao-Ling Zhang, Bin Guo, Zhan-Peng Yu. Effects of PTHrP on expression of MMP9 and MMP13 in sika deer antler chondrocytes. Cell biology international. vol 37. issue 12. 2014-05-28. PMID:23956041. |
we have determined the role of pthrp on the mrna expression of matrix metalloproteinase-9 (mmp9) and mmp13 in the antler chondrocytes. |
2014-05-28 |
2023-08-12 |
Not clear |
| Kyle A DiVito, Cynthia M Simbulan-Rosenthal, You-Shin Chen, Valerie A Trabosh, Dean S Rosentha. Id2, Id3 and Id4 overcome a Smad7-mediated block in tumorigenesis, generating TGF-β-independent melanoma. Carcinogenesis. vol 35. issue 4. 2014-05-27. PMID:24343358. |
downstream, ids suppressed cyclin-dependent kinase inhibitors, and re-upregulated invasion and metastasis-related genes matrix metalloproteinase 2 (mmp2), mmp9, cxcr4 and osteopontin, shown previously to be downregulated in response to smad7. |
2014-05-27 |
2023-08-12 |
mouse |
| Sophia E Tsiligiannis, Marina Zaitseva, Peter R Coombs, Paul Shekleton, Moshe Olshansky, Martha Hickey, Beverley Vollenhoven, Peter A W Roger. Fibroid-associated heavy menstrual bleeding: correlation between clinical features, Doppler ultrasound assessment of vasculature, and tissue gene expression profiles. Reproductive sciences (Thousand Oaks, Calif.). vol 20. issue 4. 2014-05-19. PMID:22995988. |
we identified 19 angiogenesis pathway-related genes with significant differences in expression between f and dm, and 2 genes, matrix metalloproteinase 9 (mmp9) and neuropilin 2 (nrp2), that were significantly different between f and pm. |
2014-05-19 |
2023-08-12 |
human |
| X Wu, T Liu, O Fang, L J Leach, X Hu, Z Lu. miR-194 suppresses metastasis of non-small cell lung cancer through regulating expression of BMP1 and p27(kip1). Oncogene. vol 33. issue 12. 2014-05-07. PMID:23584484. |
the resulting downregulation of bmp1 leads to suppression of tgfβ activity and, thus, to downregulation of the expression of key oncogenic genes (matrix metalloproteinases mmp2 and mmp9). |
2014-05-07 |
2023-08-12 |
Not clear |
| Yoshihiro Morifuji, Hideya Onishi, Hironori Iwasaki, Akira Imaizumi, Kenji Nakano, Masao Tanaka, Mitsuo Katan. Reoxygenation from chronic hypoxia promotes metastatic processes in pancreatic cancer through the Hedgehog signaling. Cancer science. vol 105. issue 3. 2014-05-06. PMID:24397700. |
gli1 knockdown inhibited reoxygenation-induced increases in proliferation and tumorigenicity and decreased invasiveness through suppression of matrix metalloproteinase (mmp) 2 and mmp9. |
2014-05-06 |
2023-08-12 |
Not clear |
| Hong Chen, Bangwei Luo, Xiaofeng Yang, Jian Xiong, Zongwei Liu, Man Jiang, Rongchen Shi, Chuansheng Yan, Yuzhang Wu, Zhiren Zhan. Therapeutic effects of nonerythropoietic erythropoietin analog ARA290 in experimental autoimmune encephalomyelitis rat. Journal of neuroimmunology. vol 268. issue 1-2. 2014-04-30. PMID:24518674. |
therapeutic (from day 7 to day 18 or from day 9 to day 19) administration of ara290 (35, 70 μg/kg, intra-peritoneal) to eae rats once daily significantly reduced the severity and shortened the duration of clinical score, reduced the accumulation of inflammatory cells in eae spinal cords and suppressed mrna levels of interleukin-1β (il-1β), il-17, tumor necrosis factor-α (tnf-α), interferon-γ (ifn-γ), inducible nitric oxide synthase (inos), matrix metalloproteinase 9 (mmp9) and transcription factor t-bet in spinal cords of eae rats. |
2014-04-30 |
2023-08-12 |
rat |
| Pim J Koelink, Saskia A Overbeek, Saskia Braber, Mary E Morgan, Paul A J Henricks, Mojtaba Abdul Roda, Hein W Verspaget, Simone C Wolfkamp, Anje A te Velde, Caleb W Jones, Patricia L Jackson, J Edwin Blalock, Rolf W Sparidans, John A W Kruijtzer, Johan Garssen, Gert Folkerts, Aletta D Kranevel. Collagen degradation and neutrophilic infiltration: a vicious circle in inflammatory bowel disease. Gut. vol 63. issue 4. 2014-04-23. PMID:23525573. |
pgp is derived from collagen by the combined action of matrix metalloproteinase (mmp) 8 and/or mmp9 and prolyl endopeptidase (pe). |
2014-04-23 |
2023-08-12 |
Not clear |
| Chandra Prakash Prasad, Shivendra Kumar Chaurasiya, Lena Axelsson, Tommy Andersso. WNT-5A triggers Cdc42 activation leading to an ERK1/2 dependent decrease in MMP9 activity and invasive migration of breast cancer cells. Molecular oncology. vol 7. issue 5. 2014-04-18. PMID:23727359. |
to gain information on how erk1/2 can mediate its effect on breast cancer cell migration and invasion, we next investigated and demonstrated that wnt-5a signaling and constitutively active cdc42 both decreased matrix metalloproteinase 9 (mmp9) activity. |
2014-04-18 |
2023-08-12 |
Not clear |