| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bryan Simard, Boguslaw Tomanek, Frank C J M van Veggel, Abedelnasser Abulro. Optimal dye-quencher pairs for the design of an "activatable" nanoprobe for optical imaging. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. vol 12. issue 10. 2014-04-18. PMID:23892541. |
signal activation upon cleavage by the matrix metalloproteinase mmp9 was proportional to the quenching efficiencies, ranging from 3-fold with cy5.5-cy5 to 67-fold with qc1-ir800. |
2014-04-18 |
2023-08-12 |
Not clear |
| T V Kvetnaia, N S Lin'kova, E V Sedov, S U Mursalov, K L Kozlo. [The expression of differential and matrix remodelling factors in human buccal epithelium in aging]. Advances in gerontology = Uspekhi gerontologii. vol 26. issue 3. 2014-04-15. PMID:24640689. |
the expression of signaling molecules mmp2, mmp9, erbb3, cxcl12, nkx2.5, cd90 (the markers of remodeling intracellular matrix and cell differentiation) in human buccal epithelium in ageing has been studied. |
2014-04-15 |
2023-08-12 |
human |
| Manoj Nepal, Hwa Jung Choi, Bo-Yun Choi, Moon-Shik Yang, Jung-Il Chae, Liang Li, Yunjo So. Hispidulin attenuates bone resorption and osteoclastogenesis via the RANKL-induced NF-κB and NFATc1 pathways. European journal of pharmacology. vol 715. issue 1-3. 2014-04-14. PMID:23791609. |
the inhibitory effect on in vitro osteoclastogenesis was evaluated by counting the number of tartrate-resistant acid phosphatase (trap)-positive multinucleated cells and by measuring the expression levels of osteoclast-specific genes such as matrix metalloproteinase 9 (mmp9), trap and cathepsin k. similarly, hispidulin significantly inhibited osteoclast activity in raw 264.7 cell as well as stimulated the alp activity of mc3t3e1 cells. |
2014-04-14 |
2023-08-12 |
mouse |
| Ping Cheng, Weiqi Dai, Fan Wang, Jie Lu, Miao Shen, Kan Chen, Jingjing Li, Yan Zhang, Chengfen Wang, Jing Yang, Rong Zhu, Huawei Zhang, Yuanyuan Zheng, Chuan-Yong Guo, Ling X. Ethyl pyruvate inhibits proliferation and induces apoptosis of hepatocellular carcinoma via regulation of the HMGB1-RAGE and AKT pathways. Biochemical and biophysical research communications. vol 443. issue 4. 2014-04-14. PMID:24361892. |
moreover, ep decreased the expression of hmgb1, rage, p-akt and matrix metallopeptidase-9 (mmp9) and increased the bax/bcl-2 ratio. |
2014-04-14 |
2023-08-12 |
Not clear |
| Marta E Polak, Stephen M Thirdborough, Chuin Y Ung, Tim Elliott, Eugene Healy, Tom C Freeman, Michael R Ardern-Jone. Distinct molecular signature of human skin Langerhans cells denotes critical differences in cutaneous dendritic cell immune regulation. The Journal of investigative dermatology. vol 134. issue 3. 2014-04-09. PMID:24005050. |
conversely, tnf-α induced classical activation in ddcs with early downregulation of surface receptors (mannose receptor-1 (mrc1) and c-type lectins), and subsequent upregulation of cytokines, chemokines (il1a, il1b, and ccl18), and matrix metalloproteinases (mmp1, mmp3, and mmp9; p<0.05-p<0.0001). |
2014-04-09 |
2023-08-12 |
human |
| Dian Zhang, Yu-hua Li, Man Mi, Feng-Liang Jiang, Zheng-gang Yue, Yang Sun, Lei Fan, Jin Meng, Xin Zhang, Li Liu, Qi-Bing Me. Modified apple polysaccharides suppress the migration and invasion of colorectal cancer cells induced by lipopolysaccharide. Nutrition research (New York, N.Y.). vol 33. issue 10. 2014-04-04. PMID:24074742. |
map significantly decreased lps-induced expression of tlr4, cyclooxygenase-2, matrix metallopeptidase 9 (mmp9), matrix metallopeptidase 2, inducible nitric oxide synthase, and prostaglandin e2, and it increased the protein expression of the inhibitor of κbα and nf-κb p65 in cytoplasm when it was given in combination with lps. |
2014-04-04 |
2023-08-12 |
Not clear |
| Abebayehu N Yilma, Shree R Singh, Saurabh Dixit, Vida A Denni. Anti-inflammatory effects of silver-polyvinyl pyrrolidone (Ag-PVP) nanoparticles in mouse macrophages infected with live Chlamydia trachomatis. International journal of nanomedicine. vol 8. 2014-04-02. PMID:23882139. |
of significance, ag-pvp nanoparticles (10 nm) caused perturbations in a variety of upstream (toll like receptor 2 [tlr2], nucleotide-binding oligomerization-protein 2 [nod2], cluster of differentiation [cd]40, cd80, and cd86) and downstream (il-1 receptor-associated kinase 3 [irak3] and matrix metallopeptidase 9 [mmp9]) inflammatory signaling pathways by downregulating their messenger ribonucleic acid (mrna) gene transcript expressions as induced by c. trachomatis in macrophages. |
2014-04-02 |
2023-08-12 |
mouse |
| Hongqiang Wang, Baohua Zhu, Zhiwei He, Hui Fu, Zhong Dai, Guoliang Huang, Binbin Li, Dongyun Qin, Xiaoyan Zhang, Lu Tian, Weiyi Fang, Huiling Yan. Deuterium-depleted water (DDW) inhibits the proliferation and migration of nasopharyngeal carcinoma cells in vitro. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 67. issue 6. 2014-03-31. PMID:23773852. |
western blot analysis revealed that treatment with ddw significantly increased the expression of nadph:quinone oxidoreductase-1 (nqo1), while immunofluorescence assay analysis revealed that treatment with ddw decreased the expression of pcna and matrix metalloproteinase 9 (mmp9) in npc cells. |
2014-03-31 |
2023-08-12 |
Not clear |
| Jeremy Molligan, Lew Schon, Zijun Zhan. A stereologic study of the plantar fat pad in young and aged rats. Journal of anatomy. vol 223. issue 5. 2014-03-28. PMID:24033117. |
immunohistochemistry of matrix metalloproteinase 9 (mmp9) was also performed on pfp tissue sections. |
2014-03-28 |
2023-08-12 |
rat |
| Susanne Schiffmann, Andreas Weigert, Julia Männich, Max Eberle, Kerstin Birod, Annett Häussler, Nerea Ferreiros, Yannick Schreiber, Hana Kunkel, Manuel Grez, Benjamin Weichand, Bernhard Brüne, Waltraud Pfeilschifter, Rolf Nüsing, Ellen Niederberger, Sabine Grösch, Klaus Scholich, Gerd Geisslinge. PGE2/EP4 signaling in peripheral immune cells promotes development of experimental autoimmune encephalomyelitis. Biochemical pharmacology. vol 87. issue 4. 2014-03-27. PMID:24355567. |
moreover, mice lacking cox-2 or ep4 in bone marrow-derived cells show a reduced expression of matrix metalloproteinase 9 (mmp9), which results in decreased infiltration of monocytes and t cells into the cns. |
2014-03-27 |
2023-08-12 |
mouse |
| Xingjun Feng, Guozhuan Miao, Yipeng Han, Yi X. CARMA3 is overexpressed in human glioma and promotes cell invasion through MMP9 regulation in A172 cell line. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 35. issue 1. 2014-03-26. PMID:23893382. |
in addition, mrna and protein levels of matrix metallopeptidase 9 (mmp9) were downregulated, indicating carma3 might regulate invasion through mmp9. |
2014-03-26 |
2023-08-12 |
human |
| Bilge Debelec-Butuner, Cansu Alapinar, Lokman Varisli, Burcu Erbaykent-Tepedelen, Syed Muhammad Hamid, Ceren Gonen-Korkmaz, Kemal Sami Korkma. Inflammation-mediated abrogation of androgen signaling: an in vitro model of prostate cell inflammation. Molecular carcinogenesis. vol 53. issue 2. 2014-03-25. PMID:22911881. |
prostate cells were then fed with cm containing varying concentrations of tnfα, and ikb degradation, nuclear factor kappa b (nfκb) translocation and transactivation, and the expression of matrix metalloproteinase-8 (mmp8) and matrix metalloproteinase-9 (mmp9) were then assessed. |
2014-03-25 |
2023-08-12 |
Not clear |
| Elena Ioana Braicu, Khayal Gasimli, Rolf Richter, Mani Nassir, Sherko Kümmel, Jens-Uwe Blohmer, Isil Yalcinkaya, Radoslav Chekerov, Iulia Ignat, Andra Ionescu, Monika Mentze, Christina Fotopoulou, Carmen Pop, Werner Lichtenegger, Jalid Sehoul. Role of serum VEGFA, TIMP2, MMP2 and MMP9 in monitoring response to adjuvant radiochemotherapy in patients with primary cervical cancer--results of a companion protocol of the randomized NOGGO-AGO phase III clinical trial. Anticancer research. vol 34. issue 1. 2014-03-25. PMID:24403492. |
the aim of the current study was to analyze the type of variations in expression profiles of matrix metalloproteinase 2 (mmp2), matrix metalloproteinase 9 (mmp9), tissue inhibitor of metalloproteinase 2 (timp2), and vascular endothelial growth factor a (vegfa) before and after radiochemotherapy in patients with locally advanced figo stage ib-iib cervical cancer. |
2014-03-25 |
2023-08-12 |
Not clear |
| Pedro González-Muniesa, María Pilar Marrades, José Alfredo Martínez, María Jesús Moreno-Aliag. Differential proinflammatory and oxidative stress response and vulnerability to metabolic syndrome in habitual high-fat young male consumers putatively predisposed by their genetic background. International journal of molecular sciences. vol 14. issue 9. 2014-03-19. PMID:23975165. |
genes involved in inflammation (alcam, ctsb, c1s, ykl-40, mif, saa2), extracellular matrix remodeling (mmp9, palld), angiogenesis (egfl6, leptin) and oxidative stress (akr1c3, uchl1, hspb7 and nqo1) were upregulated; whereas apoptosis, signal transcription (cited 2 and nr3c1), cell control and cell cycle-related genes were downregulated. |
2014-03-19 |
2023-08-12 |
human |
| Zilan Lv, Dandan Yang, Jie Li, Min Hu, Min Luo, Xiaoqin Zhan, Peipei Song, Chen Liu, Huili Bai, Baolin Li, Yang Yang, Yingying Chen, Qiong Shi, Yaguang Wen. Bone morphogenetic protein 9 overexpression reduces osteosarcoma cell migration and invasion. Molecules and cells. vol 36. issue 2. 2014-03-14. PMID:23807047. |
we further investigated the expression of a panel of cancer-related genes and found that bmp9 overexpression increased the phosphorylation of smad1/5/8 proteins, increased the expression of id1, and reduced the expression and activity of matrix metalloproteinase 9 (mmp9) in os cells. |
2014-03-14 |
2023-08-12 |
human |
| Joan Blin, Zalinah Ahmad, Lekhraj Rampal S O Gyanchand Rampal, Norhafizah Mohtarrudin, Abdul Karim Haji Tajudin, Rohayu Shahar Adna. Preliminary assessment of differential expression of candidate genes associated with atherosclerosis. Genes & genetic systems. vol 88. issue 3. 2014-03-14. PMID:24025248. |
this preliminary study was aimed at assessing the expression levels of 11 candidate genes, namely tumor protein (tp53), transforming growth factor, beta receptor ii (tgfbr2), cysthathionenine-beta-synthase (cbs), insulin receptor substrate 1 (irs1), lipoprotein lipase (lpl), methylenetetrahydrofolate reductase (mthfr), thrombomodulin (thbd), lecithin-cholesterol acyltransferase (lcat), matrix metallopeptidase 9 (mmp9), low density lipoprotein receptor (ldlr), and arachidonate 5-lipoxygenase-activating protein (alox5ap) genes associated with ath. |
2014-03-14 |
2023-08-12 |
human |
| Daniela Di Paolo, Fabio Pastorino, Guendalina Zuccari, Irene Caffa, Monica Loi, Danilo Marimpietri, Chiara Brignole, Patrizia Perri, Michele Cilli, Beatrice Nico, Domenico Ribatti, Vito Pistoia, Mirco Ponzoni, Gabriella Pagna. Enhanced anti-tumor and anti-angiogenic efficacy of a novel liposomal fenretinide on human neuroblastoma. Journal of controlled release : official journal of the Controlled Release Society. vol 170. issue 3. 2014-03-11. PMID:23792118. |
indeed, in this group of mice a marked reduction of tumor progression, of intra-tumoral vessel counts and vegf expression, together with a marked down-modulation of matrix metalloproteinases mmp2 and mmp9, was observed. |
2014-03-11 |
2023-08-12 |
mouse |
| Edyta Wieczorek, Edyta Reszka, Zbigniew Jablonowski, Ewa Jablonska, Magdalena Beata Krol, Adam Grzegorczyk, Jolanta Gromadzinska, Marek Sosnowski, Wojciech Wasowic. Genetic polymorphisms in matrix metalloproteinases (MMPs) and tissue inhibitors of MPs (TIMPs), and bladder cancer susceptibility. BJU international. vol 112. issue 8. 2014-03-11. PMID:23819551. |
to elucidate genetic polymorphisms of the matrix metalloproteinases (mmps) mmp1 (rs1799750), mmp2 (rs243865), mmp9 (rs3918242), mmp12 (rs2276109) and tissue inhibitors of mmps (timps) timp1 (rs2070584) and timp3 (rs9619311) genes that may be involved in susceptibility to bladder cancer (bc). |
2014-03-11 |
2023-08-12 |
Not clear |
| Ping Jiang, Jing-He Li, Geng-Qiu Luo, Jie Li. [Effect of EphA2 protein on the expression of VEGF and MMP9 proteins in HCT116 cells]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 32. issue 4. 2014-03-10. PMID:17767065. |
to determine the effect of epha2 protein on the expression of vascular endothelial growth factor (vegf) and matrix metalloproteinase 9 (mmp9) proteins in hct116 cells. |
2014-03-10 |
2023-08-12 |
Not clear |
| A Baker, C L Wood, A M Wood, P Timms, A J Allsop. Changes in vitamin D and matrix metalloproteinase-9 in submariners during a submerged patrol. Occupational and environmental medicine. vol 71. issue 2. 2014-03-10. PMID:24306365. |
to quantify changes in vitamin d and matrix metalloproteinase-9 (mmp9) in submariners over a single long patrol and compare the data to a group of non-deploying servicemen from their base port. |
2014-03-10 |
2023-08-12 |
Not clear |