| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Phyllis F Y Cheung, Chi Wai Yip, Nicholas C L Wong, Daniel Y T Fong, Linda W C Ng, Angus M Y Wan, Chun Kwok Wong, Tan To Cheung, Irene O L Ng, Ronnie T P Poon, Sheung Tat Fan, Siu Tim Cheun. Granulin-epithelin precursor renders hepatocellular carcinoma cells resistant to natural killer cytotoxicity. Cancer immunology research. vol 2. issue 12. 2015-07-23. PMID:25315249. |
matrix metalloproteinase (mmp)2 and mmp9 activity was involved partly in the gep-regulated mica shedding from hcc cells. |
2015-07-23 |
2023-08-13 |
human |
| Ou Huang, Weili Zhang, Qiaoming Zhi, Xiaofeng Xue, Hongchun Liu, Daoming Shen, Meiyu Geng, Zuoquan Xie, Min Jian. Teriflunomide, an immunomodulatory drug, exerts anticancer activity in triple negative breast cancer cells. Experimental biology and medicine (Maywood, N.J.). vol 240. issue 4. 2015-07-20. PMID:25304315. |
among them, we identified down-regulation of growth factor receptors to abolish growth maintenance, suppression of c-myc, and cyclin d1 to contribute to its anti-proliferative effect, modulation of components of cell cycle to induce s-phase arrest, degradation of bcl-xl, and up-regulation of bax via activation of mapk pathway to induce apoptosis, and inhibition of epithelial-mesenchymal transition (emt) process, matrix metalloproteinase-9 (mmp9) expression, and inactivation of src/fak to reduce tnbc migration and invasion. |
2015-07-20 |
2023-08-13 |
human |
| Catherine K Hathaway, Ruriko Grant, John R Hagaman, Sylvia Hiller, Feng Li, Longquan Xu, Albert S Chang, Victoria J Madden, C Robert Bagnell, Mauricio Rojas, Hyung-Suk Kim, Bingruo Wu, Bin Zhou, Oliver Smithies, Masao Kakok. Endothelin-1 critically influences cardiac function via superoxide-MMP9 cascade. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 16. 2015-06-29. PMID:25848038. |
young adult l/l and l/+ mice have dilated cardiomyopathy, hypertension, and increased plasma volumes, together with increased ventricular superoxide levels, increased matrix metalloproteinase 9 (mmp9) expression, and reduced ventricular stiffness. |
2015-06-29 |
2023-08-13 |
mouse |
| Wakiro Sat. [Chemokine receptor expression of T cells in the cerebrospinal fluid of relapsing multiple sclerosis]. Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology. vol 37. issue 2. 2015-06-25. PMID:24835135. |
peripheral ccr2+ccr5+cd4+ t cells produced both ifn-γ and il-17, expressed matrix metalloproteinase-9 (mmp9) and osteopontin, and transmigrated in an in vitro blood brain barrier model more efficiently than other th cells, suggesting a bbb-invading mechanism and an important role in the relapse of ms. |
2015-06-25 |
2023-08-13 |
Not clear |
| Sen-Lin Xu, Sha Liu, Wei Cui, Yu Shi, Qin Liu, Jiang-Jie Duan, Shi-Cang Yu, Xia Zhang, You-Hong Cui, Hsiang-Fu Kung, Xiu-Wu Bia. Aldehyde dehydrogenase 1A1 circumscribes high invasive glioma cells and predicts poor prognosis. American journal of cancer research. vol 5. issue 4. 2015-06-23. PMID:26101711. |
mechanistically, both in vitro and in vivo studies revealed that aldh1a1(+) cells isolated from either a glioblastoma cell line u251 or primary glioblastoma cells displayed significant invasiveness, clonogenicity, and proliferation as compared to aldh1a1(-) cells, due to increased levels of mrna and protein for matrix metalloproteinase 2, 7 and 9 (mmp2, mmp7 and mmp9). |
2015-06-23 |
2023-08-13 |
Not clear |
| Zhang Juan, Zhang Wei-Guo, Song Heng-Liang, Wan Da-Gu. Association of Matrix Metalloproteinase 9 C-1562T Polymorphism with Genetic Susceptibility to Myocardial Infarction: A Meta-Analysis. Current therapeutic research, clinical and experimental. vol 77. 2015-06-17. PMID:26082814. |
many studies have identified the associations between matrix metalloproteinase 9 (mmp9) c-1562t polymorphisms and mi. |
2015-06-17 |
2023-08-13 |
Not clear |
| Ji-Gang Zhang, Xiao-Yu Li, Yu-Zhu Wang, Qi-Di Zhang, Sheng-Ying Gu, Xin Wu, Guan-Hua Zhu, Qin Li, Gao-Lin Li. ROCK is involved in vasculogenic mimicry formation in hepatocellular carcinoma cell line. PloS one. vol 9. issue 9. 2015-06-16. PMID:25238232. |
to elucidate the possible mechanism of rock on vm formation, real-time qpcr, western blot and immunofluorescence were used to detect changes of the key vm-related factors, including ve-cadherin, erythropoietin-producing hepatocellular carcinoma-a2 (epha2), phosphoinositide 3-kinase (pi3k), matrix metalloproteinase (mmp)14, mmp2, mmp9 and laminin 5γ2-chain (lamc2), and epithelial-mesenchymal-transition (emt) markers: e-cadherin and vimentin. |
2015-06-16 |
2023-08-13 |
Not clear |
| Suzanne Lam, Eliza Wiercinska, Amina F A S Teunisse, Kirsten Lodder, Peter ten Dijke, Aart G Jochemse. Wild-type p53 inhibits pro-invasive properties of TGF-β3 in breast cancer, in part through regulation of EPHB2, a new TGF-β target gene. Breast cancer research and treatment. vol 148. issue 1. 2015-06-16. PMID:25257729. |
pharmacological activation of p53 inhibited induction of several tgf-β3 targets involved in tgf-β3-induced tumor cell invasion, i.e., matrix metallo proteinase (mmp)2, mmp9, and integrin β 3 . |
2015-06-16 |
2023-08-13 |
human |
| Gang Liu, Shengbao Xu, Fanglei Jiao, Tao Ren, Qinchuan L. Vascular endothelial growth factor B coordinates metastasis of non-small cell lung cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 36. issue 3. 2015-06-15. PMID:25424698. |
both vascular endothelial growth factor b (vegf-b) and matrix metalloproteinases 9 (mmp9) play essential roles in neovascularization of nsclc. |
2015-06-15 |
2023-08-13 |
human |
| Xiyu Liu, Changyan Pei, Song Yan, Guifeng Liu, Gang Liu, Wenqing Chen, Youbin Cui, Yahui Li. NADPH oxidase 1-dependent ROS is crucial for TLR4 signaling to promote tumor metastasis of non-small cell lung cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 36. issue 3. 2015-06-15. PMID:25592377. |
further, nox1 could regulate the expression of cxcr4 and matrix metallopeptidase 9 (mmp9) in nsclc cells. |
2015-06-15 |
2023-08-13 |
Not clear |
| Phuongmai Nguyen, Sunmin Lee, Dominique Lorang-Leins, Jane Trepel, DeeDee K Smar. SIRT2 interacts with β-catenin to inhibit Wnt signaling output in response to radiation-induced stress. Molecular cancer research : MCR. vol 12. issue 9. 2015-06-05. PMID:24866770. |
in sirt2 null mefs, an upregulation of matrix metalloproteinase 9 (mmp9) and decreased e-cadherin (cdh1) expression is observed that produces increased cellular migration and invasion. |
2015-06-05 |
2023-08-13 |
mouse |
| Fan Wang, Peng Zhang, Lang Yang, Xi Yu, Xianzhong Ye, Jing Yang, Cheng Qian, Xia Zhang, You-Hong Cui, Xiu-Wu Bia. Activation of toll-like receptor 2 promotes invasion by upregulating MMPs in glioma stem cells. American journal of translational research. vol 7. issue 3. 2015-06-05. PMID:26045899. |
the expressions of matrix metalloproteinases 2, 9 (mmp2 and mmp9) by gscs were enhanced by treatment of pam3csk4 and decreased by tlr2 knockdown, implying that mmp2 and mmp9 were involved in tlr2-mediated invasion of gscs. |
2015-06-05 |
2023-08-13 |
mouse |
| Wei Xiang, Ting Jiang, Fengjing Guo, Chen Gong, Kaixiang Yang, Yingxing Wu, Xin Huang, Weiting Cheng, Kai X. Hedgehog pathway inhibitor-4 suppresses malignant properties of chondrosarcoma cells by disturbing tumor ciliogenesis. Oncology reports. vol 32. issue 4. 2015-06-01. PMID:25110171. |
hh downstream effect molecular gli2 was restrained to block parathyroid hormone-related protein and affect mapk/erk-regulated matrix metalloproteinases (mmp2 and mmp9). |
2015-06-01 |
2023-08-13 |
human |
| Lin Li, Jinjing Tan, Ying Zhang, Naijun Han, Xuebing Di, Ting Xiao, Shujun Cheng, Yanning Gao, Yu Li. DLK1 promotes lung cancer cell invasion through upregulation of MMP9 expression depending on Notch signaling. PloS one. vol 9. issue 3. 2015-05-29. PMID:24621612. |
western blotting and gelatin zymography analysis indicated that dlk1 could affect both matrix metalloproteinase-9 (mmp9) expression and its extracellular activity. |
2015-05-29 |
2023-08-12 |
human |
| Dong-Ni Zhou, Yan-Fei Deng, Rong-Hua Li, Ping Yin, Chun-Sheng Y. Concurrent alterations of RAGE, RECK, and MMP9 protein expression are relevant to Epstein-Barr virus infection, metastasis, and survival in nasopharyngeal carcinoma. International journal of clinical and experimental pathology. vol 7. issue 6. 2015-05-26. PMID:25031745. |
this study aimed to concurrently investigate the expressions of receptor for advanced glycation end products (rage), reversion inducing cysteine-rich protein with kazal motifs (reck) and matrix metalloproteinase 9 (mmp9) in nasopharyngeal carcinoma (npc) and their correlations with clinicopathological properties. |
2015-05-26 |
2023-08-13 |
Not clear |
| Zhi Zhang, Fang Wang, Bing-Jian Wang, Guang Chu, Qunan Cao, Bao-Gui Sun, Qiu-Yan Da. Inhibition of leptin-induced vascular extracellular matrix remodelling by adiponectin. Journal of molecular endocrinology. vol 53. issue 2. 2015-05-22. PMID:24982243. |
we validated the profibrogenic effects of leptin and analysed matrix metalloproteinase 2 (mmp2), mmp9, tissue inhibitor of metalloproteinase 1 (timp1) and collagen types ii/iv secretion in 3d vessel models. |
2015-05-22 |
2023-08-13 |
Not clear |
| Toshio Kojima, Xiaofei Wang, Kyoko Fujiwara, Shunzo Osaka, Yukihiro Yoshida, Eiji Osaka, Masashi Taniguchi, Takahiro Ueno, Noboru Fukuda, Masayoshi Soma, Yasuaki Tokuhashi, Hiroki Nagas. Inhibition of human osteosarcoma cell migration and invasion by a gene silencer, pyrrole-imidazole polyamide, targeted at the human MMP9 NF-κB binding site. Biological & pharmaceutical bulletin. vol 37. issue 9. 2015-05-22. PMID:25177029. |
matrix metalloproteinase 9 (mmp9), a type iv collagenase, is a known anticancer target and is overexpressed in osteosarcomas. |
2015-05-22 |
2023-08-13 |
human |
| Yanqing Gu, Weimin Fan, Guoyong Yi. The study of mechanisms of protective effect of Rg1 against arthritis by inhibiting osteoclast differentiation and maturation in CIA mice. Mediators of inflammation. vol 2014. 2015-05-15. PMID:25214714. |
rg1 also significantly inhibited the rank signaling pathway, including suppressing the expression of trap, cathepsin k, matrix metalloproteinase 9 (mmp9), and calcitonin receptor (ctr). |
2015-05-15 |
2023-08-13 |
mouse |
| Amit Ranjan, Rajiv D Kalraiy. Invasive potential of melanoma cells correlates with the expression of MT1-MMP and regulated by modulating its association with motility receptors via N-glycosylation on the receptors. BioMed research international. vol 2014. 2015-05-14. PMID:25180193. |
using high metastatic b16f10 and its invasive variant b16bl6 cells, we previously demonstrated that the expression of β1,6 branched n-oligosaccharides promotes cellular adhesion on different matrix components which in turn induces secretion of mmp9. |
2015-05-14 |
2023-08-13 |
Not clear |
| Peng Zhang, Ying Lu, Xue You Liu, Yu Hua Zho. Knockdown of Rho-associated protein kinase 1 suppresses proliferation and invasion of glioma cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 36. issue 1. 2015-05-11. PMID:25266804. |
in addition, the effects of rock1 on the regulation of ki67, cyclin d1, matrix metalloproteinases 9 (mmp9), and e-cadherin were also investigated. |
2015-05-11 |
2023-08-13 |
Not clear |