| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hyunjung Min, Boomin Choi, Yong Ho Jang, Ik-Hyun Cho, Sung Joong Le. Heme molecule functions as an endogenous agonist of astrocyte TLR2 to contribute to secondary brain damage after intracerebral hemorrhage. Molecular brain. vol 10. issue 1. 2018-04-16. PMID:28646881. |
this effect was most likely due to reduced matrix metalloproteinase 9 (mmp9) activity in the tlr2 ko mice compared to wt mice. |
2018-04-16 |
2023-08-13 |
mouse |
| Yadong Wang, Haiyu Wang, Teng Pan, Li Li, Jiangmin Li, Haiyan Yan. STIM1 silencing inhibits the migration and invasion of A549 cells. Molecular medicine reports. vol 16. issue 3. 2018-04-16. PMID:28713917. |
the protein expression levels of snail1, vimentin, matrix metalloproteinase (mmp) 2 and mmp9 were markedly decreased in a549‑shstim1 compared with in a549 cells transfected with control shrna (shcon). |
2018-04-16 |
2023-08-13 |
Not clear |
| Adina Zamfir-Chiru-Anton, Cristian Gheorghe Da. Implication of gelatinases in retinoblastoma development. Romanian journal of ophthalmology. vol 60. issue 2. 2018-04-12. PMID:29450326. |
the aim of this paper was to reveal the latest clinical and research findings regarding the implications of mmp2 and mmp9 matrix metalloproteinases in retinoblastoma development. |
2018-04-12 |
2023-08-13 |
Not clear |
| Patrizia Farina, Emeline Tabouret, Pierre Lehmann, Maryline Barrie, Gregorio Petrirena, Chantal Campello, Celine Boucard, Thomas Graillon, Nadine Girard, Olivier Chino. Relationship between magnetic resonance imaging characteristics and plasmatic levels of MMP2 and MMP9 in patients with recurrent high-grade gliomas treated by Bevacizumab and Irinotecan. Journal of neuro-oncology. vol 132. issue 3. 2018-04-11. PMID:28265824. |
matrix metalloproteases mmp2 and mmp9 are involved in cancer angiogenesis and invasion. |
2018-04-11 |
2023-08-13 |
Not clear |
| Yongqu Lu, Jie An, Yulin Liu, Lehao Ren, Li Zhan. MMP9 is involved in HO-1-mediated upregulation of apical junctional complex in Caco-2 cells under oxygen-glucose deprivation. Biochemical and biophysical research communications. vol 498. issue 1. 2018-04-06. PMID:29425821. |
notably, activation of ho-1 largely enhanced the expression of ajc proteins including claudin-4, e-cadherin and β-catenin in caco-2 cells, but decreased the expression of matrix metalloproteinase 9 (mmp9). |
2018-04-06 |
2023-08-13 |
Not clear |
| Chen Yu, Yang Lixia, Guo Ruiwei, Shi Yankun, Ye Jinsha. The Role of FAK in the Secretion of MMP9 after CD147 Stimulation in Macrophages. International heart journal. vol 59. issue 2. 2018-04-06. PMID:29563383. |
to investigate whether focal adhesion kinase (fak) can participate in the secretion of matrix metalloproteinase 9 (mmp9) after cd147 stimulation in thp-1 induced macrophages; thus, to explore the potential treatment perspectives for acute coronary syndrome (acs).phorbol-12-myristate-13-acetate (pma) was used to induce thp-1 cells to differentiate into macrophages. |
2018-04-06 |
2023-08-13 |
Not clear |
| Shingo Haneda, Kentaro Nagaoka, Yasuo Nambo, Masato Kikuchi, Yasuko Nakano, Junyou Li, Motozumi Matsui, Yo-Ichi Miyake, Kazuhiko Imakaw. Expression of uterine lipocalin 2 and its receptor during early- to mid-pregnancy period in mares. The Journal of reproduction and development. vol 63. issue 2. 2018-03-26. PMID:27980236. |
the presence of matrix metalloproteinase-9 (mmp9) was also examined because mmp9 is known to form a complex with lcn2. |
2018-03-26 |
2023-08-13 |
Not clear |
| Michelle Limoge, Alfiya Safina, Amy Beattie, Lauren Kapus, Alexander M Truskinovsky, Andrei V Baki. Tumor-fibroblast interactions stimulate tumor vascularization by enhancing cytokine-driven production of MMP9 by tumor cells. Oncotarget. vol 8. issue 22. 2018-03-26. PMID:28423685. |
these cytokines cooperatively induced expression of matrix metalloproteinase mmp9 in tumor cells. |
2018-03-26 |
2023-08-13 |
Not clear |
| Haiqiong Ye, Yujiao Zhang, Yongzhou Wang, Jiyi Xia, Xiguang Mao, Xiaolan Y. The restraining effect of baicalein and U0126 on human cervical cancer cell line HeLa. Molecular medicine reports. vol 16. issue 1. 2018-03-26. PMID:28560420. |
baicalein and u0126 markedly downregulated extracellular signal‑regulated kinase 1/2, matrix metalloproteinase (mmp) 2 and mmp9 levels both in mrna and protein. |
2018-03-26 |
2023-08-13 |
human |
| Li Xu, Jinquan Li, Zhen Bao, Peng Xu, Hao Chang, Jingjing Wu, Yuanqi Bei, Liuwan Xia, Peizhang Wu, Ke Yan, Bing Lu, Gang Cu. Silencing of OTUB1 inhibits migration of human glioma cells in vitro. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 37. issue 3. 2018-03-14. PMID:28139865. |
furthermore, down-regulated expression of otub1 also resulted in decreased expression of some extracellular matrix degradation-related proteins, such as matrix metallopeptidase (mmp)2 and mmp9. |
2018-03-14 |
2023-08-13 |
human |
| Patricia G Tremblay, Marc-André Sirar. Transcriptomic analysis of gene cascades involved in protein kinase A and C signaling in the KGN line of human ovarian granulosa tumor cells†. Biology of reproduction. vol 96. issue 4. 2018-03-12. PMID:28383663. |
gene associations with seven major ovarian functions were identified: prostaglandin- endoperoxide synthase 2 (ptgs2), interleukin 8 (il8), and interleukin 6 (il6) with inflammation; steroidogenic acute regulatory protein (star), cytochrome p450scc (cyp11a1), and cytochrome p450 family 19 subfamily a member 1 (cyp19a1) with steroidogenesis; vascular endothelial growth factor c (vegfc), vascular endothelial growth factor a (vegfa), and c-x-c chemokine receptor type 4 (cxcr4) with angiogenesis; amphiregulin (areg), epidermal growth factor receptor (egfr), and sprouty rtk signaling antagonist 2 (spry2) with differentiation, bcl2 associated x (bax), bcl2 like 12 (bcl2l12), and caspase 1(casp1) with apoptosis, cyclin d1 (ccnd1), cyclin b1 (ccnb1), and cyclin b2 (ccnb2) with division; and matrix metalloproteinase-1 (mmp1), matrix metallopeptidase 9 (mmp9), and timp metallopeptidase inhibitor 1 (timp1) with ovulation. |
2018-03-12 |
2023-08-13 |
human |
| Tian-Yue Wang, Qian-Lan Zhou, Miao Li, Yun-Xiao Shan. Shikonin alleviates allergic airway remodeling by inhibiting the ERK-NF-κB signaling pathway. International immunopharmacology. vol 48. 2018-03-12. PMID:28521243. |
furthermore, the abnormal activation of extracellular signal-regulated kinase (erk)/nuclear factor-κb (nf-κb) pathway and the elevation of matrix metalloproteinase 9 (mmp9) in the lung of asthmatic mice were suppressed by shikonin. |
2018-03-12 |
2023-08-13 |
mouse |
| Tian-Yue Wang, Qian-Lan Zhou, Miao Li, Yun-Xiao Shan. Shikonin alleviates allergic airway remodeling by inhibiting the ERK-NF-κB signaling pathway. International immunopharmacology. vol 48. 2018-03-12. PMID:28521243. |
in addition, asmcs exposed to pdgf acquired an enhanced migratory ability, and the activities of mmp9 and matrix metalloproteinase 2 (mmp2) and expression of mmp9 of these cells were significantly up-regulated. |
2018-03-12 |
2023-08-13 |
mouse |
| Deepika Ramu, Vettriselvi Venkatesan, Solomon Franklin Durairaj Paul, Teena Kosh. Genetic variation in matrix metalloproteinase MMP2 and MMP9 as a risk factor for idiopathic recurrent spontaneous abortions in an Indian population. Journal of assisted reproduction and genetics. vol 34. issue 7. 2018-03-05. PMID:28500450. |
genetic variation in matrix metalloproteinase mmp2 and mmp9 as a risk factor for idiopathic recurrent spontaneous abortions in an indian population. |
2018-03-05 |
2023-08-13 |
Not clear |
| Deepika Ramu, Vettriselvi Venkatesan, Solomon Franklin Durairaj Paul, Teena Kosh. Genetic variation in matrix metalloproteinase MMP2 and MMP9 as a risk factor for idiopathic recurrent spontaneous abortions in an Indian population. Journal of assisted reproduction and genetics. vol 34. issue 7. 2018-03-05. PMID:28500450. |
matrix metalloproteinases, mmp2 and mmp9, are found to have an important role during ovulation and pregnancy because of their capacity to degrade components of the extracellular matrix (ecm) thereby facilitating cell migration and angiogenesis. |
2018-03-05 |
2023-08-13 |
Not clear |
| Shanshan Yan, Xiuchun Li, Jing Dai, Yiqun Wang, Binbin Wang, Yi Lu, Jianlin Shi, Pengyu Huang, Jinkang Gong, Yuan Ya. Electrospinning of PVA/sericin nanofiber and the effect on epithelial-mesenchymal transition of A549 cells. Materials science & engineering. C, Materials for biological applications. vol 79. 2018-03-05. PMID:28629038. |
gene expression analysis was conducted by real-time pcr using multiple markers for detecting emt: n-cadherin (ncad), vimentin (vim), fibronectin (fib) and matrix metallopeptidase (mmp9). |
2018-03-05 |
2023-08-13 |
Not clear |
| Anushruti Ashok, Nagendra Kumar Rai, Waseem Raza, Rukmani Pandey, Sanghamitra Bandyopadhya. Chronic cerebral hypoperfusion-induced impairment of Aβ clearance requires HB-EGF-dependent sequential activation of HIF1α and MMP9. Neurobiology of disease. vol 95. 2018-02-27. PMID:27431094. |
delving into bbb disruption mechanism demonstrated hb-egf-mediated stimulation of matrix metalloprotease-9 (mmp9), which affected bbb via hb-egf-ectodomain shedding and epidermal growth factor receptor activation. |
2018-02-27 |
2023-08-13 |
mouse |
| Sami A Anjum, Helen Lawrence, James P Holland, John A Kirby, David J Deehan, Alison J Tyson-Cappe. Effect of cobalt-mediated Toll-like receptor 4 activation on inflammatory responses in endothelial cells. Oncotarget. vol 7. issue 47. 2018-02-26. PMID:27835611. |
although sicam-1 can be generated through activity of matrix metalloproteinase-9 (mmp-9), we did not find any changes in mmp9 expression following co2+ stimulation.in summary we show that co2+ can induce endothelial inflammation via activation of tlr4. |
2018-02-26 |
2023-08-13 |
human |
| Z M Shi, Y N Liu, B Fu, Y F Shen, L M L. Expression profile of eukaryotic translation initiation factor and matrix metalloproteinase 9 in endometrial cancer tissue. Journal of biological regulators and homeostatic agents. vol 31. issue 4. 2018-02-22. PMID:29254314. |
the aim of the present study was to provide a novel method for the diagnosis, prevention and treatment of endometrial cancer by the determination of the characteristic expression of the eukaryotic translation initiation factor 4e (eif4e) and the enzyme matrix metalloproteinase 9 (mmp9) in endometrial cancer tissue. |
2018-02-22 |
2023-08-13 |
Not clear |
| Jiaqi Liu, Wenjie Luan, Yong Zhang, Jianying Gu, Yuedong Shi, Yanwen Yang, Zihao Feng, Fazhi Q. HDAC6 interacts with PTPN1 to enhance melanoma cells progression. Biochemical and biophysical research communications. vol 495. issue 4. 2018-02-22. PMID:29278704. |
furthermore, we found that matrix metallopeptidase 9 (mmp9) was increased by hdac6/ptpn1/erk1/2 axis, which might serve as a mechanism for melanoma invasion and metastasis. |
2018-02-22 |
2023-08-13 |
Not clear |