| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lewins Walter, Adani Pujada, Noopur Bhatnagar, Agnieszka B Bialkowska, Vincent W Yang, Hamed Laroui, Pallavi Gar. Epithelial derived-matrix metalloproteinase (MMP9) exhibits a novel defensive role of tumor suppressor in colitis associated cancer by activating MMP9-Notch1-ARF-p53 axis. Oncotarget. vol 8. issue 1. 2018-02-21. PMID:27861153. |
matrix-metalloproteinase (mmp9) is one of the essential regulators of extra cellular matrix components. |
2018-02-21 |
2023-08-13 |
mouse |
| Stefania Schiavone, Emanuela Mhillaj, Margherita Neri, Maria Grazia Morgese, Paolo Tucci, Maria Bove, Mario Valentino, Giuseppe Di Giovanni, Cristoforo Pomara, Emanuela Turillazzi, Luigia Trabace, Vincenzo Cuom. Early Loss of Blood-Brain Barrier Integrity Precedes NOX2 Elevation in the Prefrontal Cortex of an Animal Model of Psychosis. Molecular neurobiology. vol 54. issue 3. 2018-02-07. PMID:26910819. |
the expression of specific markers of bbb integrity, such as matrix metalloproteinase 2 (mmp2), matrix metalloproteinase 9 (mmp9), occludin 1, and plasmalemmal vesicle associated protein-1 (pv-1), was also significantly altered after 1 week of social isolation. |
2018-02-07 |
2023-08-13 |
rat |
| Min Zhang, Kang Guo, Qiong Li, Yunjian Wang, Ling Zhang, Tao He, Baishun Wan, Xiaoqian Wan. [Stem cell factor enhances invasive ability of BxPC-3 cells via hypoxia-inducible factor 1α (HIF-1α)]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 33. issue 7. 2018-02-06. PMID:28712397. |
the expressions of matrix metalloproteinase-2 (mmp2), mmp9, and urokinase type plasminogen activator (upa) were detected by real-time quantitative pcr and western blotting in bxpc-3 cells after treated with scf or sihif-1α. |
2018-02-06 |
2023-08-13 |
Not clear |
| Yue Liu, Zhen-Gang Tang, Yi Lin, Xin-Guo Qu, Wei Lv, Guo-Bin Wang, Cai-Li L. Effects of quercetin on proliferation and migration of human glioblastoma U251 cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 92. 2018-02-05. PMID:28528183. |
we further found that quercetin impaired cell migration and invasion via downregulating the expression of matrix metallopeptidases mmp9 and mmp2. |
2018-02-05 |
2023-08-13 |
human |
| Neibla Priego, María Arechederra, Celia Sequera, Paloma Bragado, Ana Vázquez-Carballo, Álvaro Gutiérrez-Uzquiza, Víctor Martín-Granado, Juan José Ventura, Marcelo G Kazanietz, Carmen Guerrero, Almudena Porra. C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms. Oncotarget. vol 7. issue 29. 2018-01-30. PMID:27286263. |
we also found that matrix metalloproteases mmp2 and mmp9 are involved in the pro-invasive effect of c3g down-regulation. |
2018-01-30 |
2023-08-13 |
Not clear |
| Petra Kotnik, Metka Koren Krajnc, Artur Pahor, Matjaž Finšgar, Željko Kne. HPLC-MS/MS method optimisation for matrix metalloproteinase 3 and matrix metalloproteinase 9 determination in human blood serum using target analysis. Journal of pharmaceutical and biomedical analysis. vol 150. 2018-01-30. PMID:29223062. |
a quantitative analysis of zinc endopeptidases matrix metalloproteinase 9 (mmp9) and matrix metalloproteinase 3 (mmp3) from human blood serum are presented. |
2018-01-30 |
2023-08-13 |
human |
| Lihong Bai, Gengpeng Lin, Longhua Sun, Yangli Liu, Xinyan Huang, Chuangjie Cao, Yubiao Guo, Canmao Xi. Upregulation of SIRT6 predicts poor prognosis and promotes metastasis of non-small cell lung cancer via the ERK1/2/MMP9 pathway. Oncotarget. vol 7. issue 26. 2018-01-17. PMID:27777384. |
sirt6 overexpression in nsclc cell lines increased extracellular signal-regulated kinase (p-erk)1/2 phosphorylation, activated matrix metalloproteinase 9 (mmp9) and promoted tumor cell migration and invasion. |
2018-01-17 |
2023-08-13 |
Not clear |
| Anwesha Barik, Satarupa Banerjee, Santanu Dhara, Nishant Chakravort. A reductionist approach to extract robust molecular markers from microarray data series - Isolating markers to track osseointegration. Journal of biomedical informatics. vol 68. 2018-01-15. PMID:28288857. |
the results from our study revealed panels comprising of matrix metalloproteinases and collagen genes were able to track osseointegration on implant surfaces (mmp9 and col1a2 on micro-textured; mmp12 and col6a3 on superimposed nano-textured surfaces) with 100% classification accuracy, specificity and sensitivity. |
2018-01-15 |
2023-08-13 |
Not clear |
| Laura Vila, Ricard Marcos, Alba Hernánde. Long-term effects of silver nanoparticles in caco-2 cells. Nanotoxicology. vol 11. issue 6. 2018-01-04. PMID:28707555. |
as for the assayed parameters of cell transformation such as ability to growth without requiring adherence to a surface (soft-agar assay), the secretion of extracellular matrix metalloproteinase to the medium (zymography), migration capacity and ability of the secretome of exposed cells to promote tumor growth, significant effects were detected in all cases, with the exception of the extracellular matrix metalloproteinases (mmp2 and mmp9) secretion. |
2018-01-04 |
2023-08-13 |
human |
| Agnieszka Cudna, Anna Jopowicz, Paweł Mierzejewski, Iwona Kurkowska-Jastrzębsk. Serum metalloproteinase 9 levels increase after generalized tonic-clonic seizures. Epilepsy research. vol 129. 2018-01-03. PMID:27886560. |
metalloproteinase 9 (mmp9) is a member of a family of enzymes that mediate the degradation of extracellular matrix proteins, and is especially involved in blood-brain barrier maintenance. |
2018-01-03 |
2023-08-13 |
human |
| Katrin Gutsche, Elisa B Randi, Volker Blank, Daniel Fink, Roland H Wenger, Cornelia Leo, Carsten C Schol. Intermittent hypoxia confers pro-metastatic gene expression selectively through NF-κB in inflammatory breast cancer cells. Free radical biology & medicine. vol 101. 2017-12-25. PMID:27717868. |
gene array analysis of ibc cells following chronic ih (45-60 days) demonstrated increased expression of pro-metastatic genes of the extracellular matrix, such as tenascin-c (tnc; an essential factor of the metastatic niche) and matrix metalloproteinase 9 (mmp9), and of pro-inflammatory processes, such as cyclooxygenase-2 (cox-2). |
2017-12-25 |
2023-08-13 |
Not clear |
| Yu Sun, Yangshan Chen, Shuhua Li, Yiyan Lei, Di Xu, Neng Jiang, Yang Zhang, Jessica Cao, Zunfu K. NanoVelcro-captured CTC number concomitant with enhanced serum levels of MMP7 and MMP9 enables accurate prediction of metastasis and poor prognosis in patients with lung adenocarcinoma. International journal of nanomedicine. vol 12. 2017-12-25. PMID:28919743. |
circulating tumor cell (ctc) number, matrix metalloproteinase (mmp) 7, and mmp9 show great prospects as predictive biomarkers in many tumors. |
2017-12-25 |
2023-08-13 |
mouse |
| Michael A Paltsev, Victoria O Polyakova, Igor M Kvetnoy, George Anderson, Tatiana V Kvetnaia, Natalia S Linkova, Ekaterina M Paltseva, Rosa Rubino, Salvatore De Cosmo, Angelo De Cata, Gianluigi Mazzoccol. Morphofunctional and signaling molecules overlap of the pineal gland and thymus: role and significance in aging. Oncotarget. vol 7. issue 11. 2017-12-11. PMID:26943046. |
this study looks at ageing-associated alterations in pineal and thymic gland functioning evaluating common signaling molecules present in both human and animal pinealocytes and thymocytes: endocrine cell markers (melatonin, serotonin, pcreb, aanat, cgrp, vip, chromogranin Ð); cell renovation markers (p53, aif, ki67), matrix metalloproteinases (mmp2, mmp9) and lymphocytes markers (cd4, cd5, cd8, cd20). |
2017-12-11 |
2023-08-13 |
human |
| Brijendra Singh, Rajesh K Kasam, Vishwaraj Sontake, Thomas A Wynn, Satish K Madal. Repetitive intradermal bleomycin injections evoke T-helper cell 2 cytokine-driven pulmonary fibrosis. American journal of physiology. Lung cellular and molecular physiology. vol 313. issue 5. 2017-12-07. PMID:28775096. |
importantly, in vivo findings demonstrated that il-13 augments matrix metalloproteinase (mmp)-2 and mmp9 activity that has also been shown to increase migration and invasiveness of fibroblasts in the lungs during bleomycin-induced pulmonary fibrosis. |
2017-12-07 |
2023-08-13 |
mouse |
| Xiao-Yan Bai, Shujing Li, Miao Wang, Xiahui Li, Yangyang Yang, Zhaowei Xu, Bowen Li, Yanan Li, Kangkai Xia, Huan Chen, Huijian W. Krüppel-like factor 9 down-regulates matrix metalloproteinase 9 transcription and suppresses human breast cancer invasion. Cancer letters. vol 412. 2017-12-05. PMID:29107105. |
here, we found the expression of klf9 was significantly down-regulated in breast cancer and was inversely correlated with the expression of matrix metalloproteinase 9 (mmp9) in breast cancer patients. |
2017-12-05 |
2023-08-13 |
human |
| Karyn Schmidt, Cailin E Joyce, Frank Buquicchio, Adam Brown, Justin Ritz, Robert J Distel, Charles H Yoon, Carl D Novin. The lncRNA SLNCR1 Mediates Melanoma Invasion through a Conserved SRA1-like Region. Cell reports. vol 15. issue 9. 2017-11-21. PMID:27210747. |
slncr1, ar, and brn3a are specifically required for transcriptional activation of matrix metalloproteinase 9 (mmp9) and increased melanoma invasion. |
2017-11-21 |
2023-08-13 |
Not clear |
| Mei Zhang, Longjun Zha. CKAP2 Promotes Ovarian Cancer Proliferation and Tumorigenesis Through the FAK-ERK Pathway. DNA and cell biology. vol 36. issue 11. 2017-11-21. PMID:28933561. |
mrna expression levels of proliferating cell nuclear antigen (pcna), matrix metalloproteinase 2 (mmp2), matrix metalloproteinase 9 (mmp9), and snai1 were elevated in overexpressed skov3 cells. |
2017-11-21 |
2023-08-13 |
mouse |
| Ganesh Swaminathan, Venkat S Gadepalli, Ivan Stoilov, Robert P Mecham, Raj R Rao, Anand Ramamurth. Pro-elastogenic effects of bone marrow mesenchymal stem cell-derived smooth muscle cells on cultured aneurysmal smooth muscle cells. Journal of tissue engineering and regenerative medicine. vol 11. issue 3. 2017-11-20. PMID:25376929. |
our study indicates that bm-msc-derived smlcs secrete trophic factors, contained in conditioned medium (cm) from their cultures, that, when exposed to earasmc cultures in real time, stimulate elastin precursor and matrix deposition and crosslinking by these elastogenically deficient cells, with added benefits in terms of attenuating mmps, specifically mmp9. |
2017-11-20 |
2023-08-13 |
rat |
| Devon M Chenette, Adam B Cadwallader, Tiffany L Antwine, Lauren C Larkin, Jinhua Wang, Bradley B Olwin, Robert J Schneide. Targeted mRNA Decay by RNA Binding Protein AUF1 Regulates Adult Muscle Stem Cell Fate, Promoting Skeletal Muscle Integrity. Cell reports. vol 16. issue 5. 2017-11-16. PMID:27452471. |
satellite cell mrna analysis and regeneration studies demonstrate that auf1(-/-) satellite cell self-renewal is impaired due to increased stability and overexpression of are-mrnas, including cell-autonomous overexpression of matrix metalloprotease mmp9. |
2017-11-16 |
2023-08-13 |
mouse |
| Devon M Chenette, Adam B Cadwallader, Tiffany L Antwine, Lauren C Larkin, Jinhua Wang, Bradley B Olwin, Robert J Schneide. Targeted mRNA Decay by RNA Binding Protein AUF1 Regulates Adult Muscle Stem Cell Fate, Promoting Skeletal Muscle Integrity. Cell reports. vol 16. issue 5. 2017-11-16. PMID:27452471. |
secreted mmp9 degrades the skeletal muscle matrix, preventing satellite-cell-mediated regeneration and return to quiescence. |
2017-11-16 |
2023-08-13 |
mouse |