| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Franciosa, G Diluvio, F Del Gaudio, M V Giuli, R Palermo, P Grazioli, A F Campese, C Talora, D Bellavia, G D'Amati, Z M Besharat, C Nicoletti, C W Siebel, L Choy, A Rustighi, G Del Sal, I Screpanti, S Checquol. Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression. Oncogene. vol 35. issue 36. 2017-08-31. PMID:26876201. |
we demonstrate that the combined inhibition of notch3 and pin1 in the notch3-overexpressing human leukemic tall-1 cells reduces their high invasive potential, by decreasing the expression of the matrix metalloprotease mmp9. |
2017-08-31 |
2023-08-13 |
mouse |
| K Nagaoka, K Fujii, H Zhang, K Usuda, G Watanabe, M Ivshina, J D Richte. CPEB1 mediates epithelial-to-mesenchyme transition and breast cancer metastasis. Oncogene. vol 35. issue 22. 2017-08-28. PMID:26411364. |
matrix metalloproteinase 9 (mmp9) mrna, which encodes a metastasis-promoting factor, undergoes poly(a) lengthening and enhanced translation upon cpeb reduction. |
2017-08-28 |
2023-08-13 |
mouse |
| Eleanor L Davis, Corinne Sonnet, ZaWaunyka W Lazard, Gabrielle Henslee, Zbigniew Gugala, Elizabeth A Salisbury, Edward V Strecker, Thomas A Davis, Jonathan A Forsberg, Alan R Davis, Elizabeth A Olmsted-Davi. Location-dependent heterotopic ossification in the rat model: The role of activated matrix metalloproteinase 9. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 34. issue 11. 2017-08-28. PMID:26919547. |
further experimentation has shown that a potential reason for this difference may be the inability of rat to activate matrix metalloproteinase 9 (mmp9), an essential protease in mice necessary for recruitment of progenitors. |
2017-08-28 |
2023-08-13 |
mouse |
| Stephanie E Seidl, Lawrence G Pessolano, Christopher A Bishop, Michael Best, Celeste B Rich, Phillip J Stone, Barbara M Schreibe. Toll-like receptor 2 activation and serum amyloid A regulate smooth muscle cell extracellular matrix. PloS one. vol 12. issue 3. 2017-08-22. PMID:28257481. |
cultured rat aortic smooth muscle cells were treated with saa or tlr2 agonists and the effect on expression of matrix metallopeptidase 9 (mmp9) and tropoelastin studied. |
2017-08-22 |
2023-08-13 |
rat |
| Stephanie E Seidl, Lawrence G Pessolano, Christopher A Bishop, Michael Best, Celeste B Rich, Phillip J Stone, Barbara M Schreibe. Toll-like receptor 2 activation and serum amyloid A regulate smooth muscle cell extracellular matrix. PloS one. vol 12. issue 3. 2017-08-22. PMID:28257481. |
tropoelastin is an mmp9 substrate and decreased tropoelastin levels in saa-treated cells supported the concept of extracellular matrix remodeling. |
2017-08-22 |
2023-08-13 |
rat |
| Hafizurrahman Khan, Radha Dutt Singh, Ratnakar Tiwari, Siddhartha Gangopadhyay, Somendu Kumar Roy, Dhirendra Singh, Vikas Srivastav. Mercury exposure induces cytoskeleton disruption and loss of renal function through epigenetic modulation of MMP9 expression. Toxicology. vol 386. 2017-08-22. PMID:28526320. |
in this study, we have shown for the first time how mehg could epigenetically modulate matrix metalloproteinase 9(mmp9) to promote nephrotoxicity using an animal model of sub chronic mehg exposure. |
2017-08-22 |
2023-08-13 |
human |
| Xiu-Bo Sang, Zhi-Hong Zong, Li-Li Wang, Dan-Dan Wu, Shuo Chen, Bo-Liang Liu, Yang Zha. E2F-1 targets miR-519d to regulate the expression of the ras homolog gene family member C. Oncotarget. vol 8. issue 9. 2017-08-18. PMID:28146423. |
e2f1 overexpression increased rhoc, bcl-2, cyclin d1, survivin, mmp2 (matrix metalloproteinase 2), mmp9, stat3 (signal transducer and activator of transcription 3), and hur (elav-like rna-binding protein 1) expression; mir-519d overexpression decreased their expression. |
2017-08-18 |
2023-08-13 |
Not clear |
| Wen Zhu, Karen E Carney, Victoria M Pigott, Lindsay M Falgoust, Paul A Clark, John S Kuo, Dandan Su. Glioma-mediated microglial activation promotes glioma proliferation and migration: roles of Na+/H+ exchanger isoform 1. Carcinogenesis. vol 37. issue 9. 2017-08-10. PMID:27287871. |
glioma cells, via conditioned medium or non-contact glioma-microglia co-cultures, concurrently upregulated microglial expression of nhe1 protein and other microglial activation markers (inos, arginase-1, tgf-β, il-6, il-10 and the matrix metalloproteinases mt1-mmp and mmp9). |
2017-08-10 |
2023-08-13 |
Not clear |
| Zhaoxia Shen, Dongmei Zhu, Jiao Liu, Juan Chen, Yun Liu, Chunyan Hu, Zhong Li, Yuan L. 27-Hydroxycholesterol induces invasion and migration of breast cancer cells by increasing MMP9 and generating EMT through activation of STAT-3. Environmental toxicology and pharmacology. vol 51. 2017-08-08. PMID:28257824. |
here, we found that 27-hydroxycholesterol (27hc) could induce epithelial-mesenchymal transition (emt) and increase the expression of the matrix metalloproteinase 9 (mmp9) at mrna level and the active form. |
2017-08-08 |
2023-08-13 |
Not clear |
| Abitha Jacob, Erik Linklater, Brian A Bayless, Traci Lyons, Rytis Prekeri. The role and regulation of Rab40b-Tks5 complex during invadopodia formation and cancer cell invasion. Journal of cell science. vol 129. issue 23. 2017-07-31. PMID:27789576. |
this is the first study that identifies a new rab40b-tks5- and mir-204-dependent invadopodia transport pathway that regulates mmp2 and mmp9 secretion, and extracellular matrix remodeling during cancer progression. |
2017-07-31 |
2023-08-13 |
Not clear |
| Sehwan Shim, Hyo-Sun Jang, Hyun-Wook Myung, Jae Kyung Myung, Jin-Kyu Kang, Min-Jung Kim, Seung Bum Lee, Won-Suk Jang, Sun-Joo Lee, Young-Woo Jin, Seung-Sook Lee, Sunhoo Par. Rebamipide ameliorates radiation-induced intestinal injury in a mouse model. Toxicology and applied pharmacology. vol 329. 2017-07-31. PMID:28526636. |
the levels of proinflammatory cytokines and matrix metallopeptidase 9 (mmp9) were significantly reduced upon rebamipide administration. |
2017-07-31 |
2023-08-13 |
mouse |
| Naveen K Somanna, Anthony J Valente, Maike Krenz, Kerry S McDonald, Yusuke Higashi, Makoto Noda, Bysani Chandraseka. Histone deacetyltransferase inhibitors Trichostatin A and Mocetinostat differentially regulate MMP9, IL-18 and RECK expression, and attenuate Angiotensin II-induced cardiac fibroblast migration and proliferation. Hypertension research : official journal of the Japanese Society of Hypertension. vol 39. issue 10. 2017-07-28. PMID:27278287. |
treatment with trichostatin a (tsa), a broad-spectrum hdac inhibitor, restored their physical association, and attenuated ang-ii-induced mmp9 expression, il-18 induction, and extracellular matrix (collagen i, collagen iii and fibronectin) production. |
2017-07-28 |
2023-08-13 |
mouse |
| Xueli Chen, Yuhong Chen, Janey L Wiggs, Louis R Pasquale, Xinghuai Sun, Bao Jian Fa. Association of Matrix Metalloproteinase-9 (MMP9) Variants with Primary Angle Closure and Primary Angle Closure Glaucoma. PloS one. vol 11. issue 6. 2017-07-26. PMID:27272641. |
association of matrix metalloproteinase-9 (mmp9) variants with primary angle closure and primary angle closure glaucoma. |
2017-07-26 |
2023-08-13 |
Not clear |
| Xueli Chen, Yuhong Chen, Janey L Wiggs, Louis R Pasquale, Xinghuai Sun, Bao Jian Fa. Association of Matrix Metalloproteinase-9 (MMP9) Variants with Primary Angle Closure and Primary Angle Closure Glaucoma. PloS one. vol 11. issue 6. 2017-07-26. PMID:27272641. |
shorter axial length observed in patients with primary angle closure glaucoma (pacg) might be due to altered matrix metalloproteinase-9 (mmp9) activity resulting in ecm remodeling during eye growth and development. |
2017-07-26 |
2023-08-13 |
Not clear |
| Yucai Wei, Lei Zhao, Wenting He, Jingwei Yang, Chunyu Geng, Yusheng Chen, Tao Liu, Hao Chen, Yumin L. Benzo[a]pyrene promotes gastric cancer cell proliferation and metastasis likely through the Aryl hydrocarbon receptor and ERK-dependent induction of MMP9 and c-myc. International journal of oncology. vol 49. issue 5. 2017-07-13. PMID:27601158. |
further study indicated that bap promotes the expression of matrix metalloproteinase-9 (mmp9) and c-myc at mrna and protein level, and activates aryl hydrocarbon receptor (ahr) and erk pathway. |
2017-07-13 |
2023-08-13 |
human |
| Ming Ye, Zejun Fang, Hongqian Gu, Rui Song, Jiangwei Ye, Hongzhang Li, Zhiguang Wu, Shenghui Zhou, Peng Li, Xiang Cai, Xiaokun Ding, Songshan Y. Histone deacetylase 5 promotes the migration and invasion of hepatocellular carcinoma via increasing the transcription of hypoxia-inducible factor-1α under hypoxia condition. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 39. issue 6. 2017-07-11. PMID:28653891. |
and then knockdown of hypoxia-inducible factor-1α decreased the expressions of mesenchymal markers, n-cadherin, and vimentin, as well as matrix metalloproteinases, mmp7 and mmp9; however, the epithelial marker, e-cadherin, increased. |
2017-07-11 |
2023-08-13 |
Not clear |
| Mingcui Xu, Feng Zhang, Aixiu Wang, Chen Wang, Yu Cao, Ming Zhang, Mingming Zhang, Min Su, Xiaoping Zou, Guifang Xu, Yuzheng Zhug. Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Promotes Hepatic Stellate Cells Migration via Canonical NF-κB/MMP9 Pathway. PloS one. vol 11. issue 12. 2017-07-06. PMID:27907201. |
cell migration was detected by transwell assay; cell viability was evaluated by cell counting kit-8; the expression of mmp1, mmp2, mmp3, mmp7, mmp8, mmp9, mmp10, mmp11, mmp12, mmp13 gene was identified by quantitative real-time polymerase chain reaction and western blotting; the activity of matrix metalloproteinases (mmps) was tested by enzyme-linked immuno sorbent assay; small interfering rna transfection was applied for depletion of mmp9 and p65. |
2017-07-06 |
2023-08-13 |
human |
| Tokuji Tsuji, Yayoi Kurokawa, Johanna Chiche, Jacques Pouysségur, Hiroshi Sato, Hideya Fukuzawa, Masaya Nagao, Taiho Kamb. Dissecting the Process of Activation of Cancer-promoting Zinc-requiring Ectoenzymes by Zinc Metalation Mediated by ZNT Transporters. The Journal of biological chemistry. vol 292. issue 6. 2017-07-04. PMID:28028180. |
in this study, we investigated this activation process by using three cancer-promoting zinc-requiring ectoenzymes, autotaxin (atx), matrix metalloproteinase 9 (mmp9), and carbonic anhydrase ix (caix), and the chicken dt40 cell mutants that we generated; we specifically focused on clarifying whether the same or a similar activation mechanism operates in these ectoenzymes. |
2017-07-04 |
2023-08-13 |
chicken |
| Liping Feng, Carla E Ransom, Matthew K Nazzal, Terrence K Allen, Yi-Ju Li, Tracy Truong, Lauren C Potts, Patrick C Seed, Amy P Murth. The Role of Progesterone and a Novel Progesterone Receptor, Progesterone Receptor Membrane Component 1, in the Inflammatory Response of Fetal Membranes to Ureaplasma parvum Infection. PloS one. vol 11. issue 12. 2017-07-03. PMID:27977732. |
interleukin-8 (il-8), matrix metalloproteinase 9 (mmp9) and cyclooxygenase (cox-2) mrna expression were quantified by qrt-pcr. |
2017-07-03 |
2023-08-13 |
Not clear |
| Pankaj Chaturvedi, Suresh C Tyag. Epigenetic silencing of TIMP4 in heart failure. Journal of cellular and molecular medicine. vol 20. issue 11. 2017-06-30. PMID:27396717. |
tissue inhibitor of matrix metalloprotease 4 (timp4) is endogenously one of the key modulators of matrix metalloprotease 9 (mmp9) and we have reported earlier that cardiac specific timp4 instigates contractility and helps in differentiation of cardiac progenitor cells. |
2017-06-30 |
2023-08-13 |
mouse |