| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ga Bin Park, Yoon Hee Chung, Daejin Ki. Induction of galectin-1 by TLR-dependent PI3K activation enhances epithelial-mesenchymal transition of metastatic ovarian cancer cells. Oncology reports. vol 37. issue 5. 2017-05-08. PMID:28350104. |
gene silencing of tlr4 and galectin-1 with sirna decreased the expression of matrix metalloproteinase-2 (mmp2) and mmp9 and reduced mesenchymal markers in lps-treated sk‑ov‑3 cells. |
2017-05-08 |
2023-08-13 |
Not clear |
| Chia-Chen Liu, Jin Hu, Na Zhao, Jian Wang, Na Wang, John R Cirrito, Takahisa Kanekiyo, David M Holtzman, Guojun B. Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 15. 2017-04-19. PMID:28275161. |
in addition, silencing of lrp1 in astrocytes led to downregulation of several major aβ-degrading enzymes, including matrix metalloproteases mmp2, mmp9, and insulin-degrading enzyme. |
2017-04-19 |
2023-08-13 |
Not clear |
| Xiaofeng Li, Chunchun Xue, Libo Wang, Dezhi Tang, Jian Huang, Yongjian Zhao, Yan Chen, Dongfeng Zhao, Qi Shi, Yongjun Wang, Bing Sh. Osteoprotective effects of osthole in a mouse model of 5/6 nephrectomy through inhibiting osteoclast formation. Molecular medicine reports. vol 14. issue 4. 2017-04-17. PMID:27571745. |
immunohistochemistry staining and reverse transcription‑quantitative polymerase chain reaction were performed to detect the expression of nuclear factor of activated t‑cells, cytoplasmic‑1 (nfatc‑1), c‑fos, cathepsin k, trap, matrix metalloproteinase 9 (mmp9), osteoprotegerin (opg) and receptor activator for nuclear factor‑κb ligand (rankl). |
2017-04-17 |
2023-08-13 |
mouse |
| Yue Shi, Duo Zuo, Xia Wang, Meng Han, Yan W. shRNA‑mediated silencing of TARBP2 inhibits NCI‑H1299 non‑small cell lung cancer cell invasion and migration via the JNK/STAT3/AKT pathway. Molecular medicine reports. vol 14. issue 4. 2017-04-17. PMID:27599909. |
western blotting and reverse transcription‑quantitative polymerase chain reaction indicated that the protein expression levels of amyloid β (a4) precursor protein (app) and zinc finger protein 395 (znf395) were upregulated, while expression levels of pro‑metastatic proteins including interleukin (il)‑1β, il‑8, cyclooxygenase (cox)‑2, matrix metalloproteinase 2 (mmp2) and mmp9 were downregulated. |
2017-04-17 |
2023-08-13 |
human |
| Wenna Liang, Xihai Li, Houhuang Chen, Xiang Shao, Xuejuan Lin, Jianying Shen, Shanshan Ding, Jie Kang, Candong L. Expressing human SHOX in Shox2SHOX KI/KI mice leads to congenital osteoarthritis‑like disease of the temporomandibular joint in postnatal mice. Molecular medicine reports. vol 14. issue 4. 2017-04-17. PMID:27601064. |
a marked increase in matrix metalloproteinase 9 (mmp9) and mmp13 in the condyles was also observed. |
2017-04-17 |
2023-08-13 |
mouse |
| Wioletta Pietruszewska, Katarzyna Bojanowska-Poźniak, Józef Kobo. Matrix metalloproteinases MMP1, MMP2, MMP9 and their tissue inhibitors TIMP1, TIMP2, TIMP3 in head and neck cancer: an immunohistochemical study. Otolaryngologia polska = The Polish otolaryngology. vol 70. issue 3. 2017-04-10. PMID:27386931. |
matrix metalloproteinases mmp1, mmp2, mmp9 and their tissue inhibitors timp1, timp2, timp3 in head and neck cancer: an immunohistochemical study. |
2017-04-10 |
2023-08-13 |
Not clear |
| Shi-Wei Chen, Qing Zhang, Zhi-Feng Xu, Hai-Ping Wang, Yi Shi, Feng Xu, Wen-Jian Zhang, Ping Wang, Yong L. HOXC6 promotes gastric cancer cell invasion by upregulating the expression of MMP9. Molecular medicine reports. vol 14. issue 4. 2017-04-10. PMID:27573865. |
semi‑quantitative pcr was used to detect the effect of different levels of hoxc6 expression on the expression of matrix metalloproteinase (mmp)2 and mmp9 in gastric cancer cells. |
2017-04-10 |
2023-08-13 |
Not clear |
| Dong-Liang Shi, Gui-Rong Shi, Jing Xie, Xu-Zhao Du, Hao Yan. MicroRNA-27a Inhibits Cell Migration and Invasion of Fibroblast-Like Synoviocytes by Targeting Follistatin-Like Protein 1 in Rheumatoid Arthritis. Molecules and cells. vol 39. issue 8. 2017-04-07. PMID:27498552. |
in addition, the down-regulated expression of matrix metalloproteinases (mmp2, mmp9, and mmp13) and rho family proteins (rac1, cdc42, and rhoa) was detected after treatment with mir-27a in ra-fls by quantitative reverse transcription-pcr and western blot analysis. |
2017-04-07 |
2023-08-13 |
Not clear |
| Chunping Zhang, Peng Wang, Pengfei Jiang, Yongbin Lv, Changxia Dong, Xiuyu Dai, Lixia Tan, Zhenlin Wan. Upregulation of lncRNA HOTAIR contributes to IL-1β-induced MMP overexpression and chondrocytes apoptosis in temporomandibular joint osteoarthritis. Gene. vol 586. issue 2. 2017-04-06. PMID:27063559. |
furthermore, in interleukin-1β (il-1β)-induced tmj oa in vitro model (primary rabbit condylar chondrocytes), the expressions of matrix metalloproteinase (mmp)-1, mmp3, mmp9 and hotair were all dramatically increased. |
2017-04-06 |
2023-08-13 |
rabbit |
| Bo Liu, Jian Cui, Jing Sun, Juan Li, Xiuchun Han, Jie Guo, Min Yi, Norio Amizuka, Xin Xu, Minqi L. Immunolocalization of MMP9 and MMP2 in osteolytic metastasis originating from MDA-MB-231 human breast cancer cells. Molecular medicine reports. vol 14. issue 2. 2017-04-06. PMID:27278284. |
taken together, the results suggested that mmp9 and mmp2 may have their own importance in extracellular matrix degradation and trabecular bone damage in different zones of bone metastasis, including the metaphysis and diaphysis. |
2017-04-06 |
2023-08-13 |
mouse |
| Mingjing Yuan, Hui Guo, Jing Li, Chengzhi Sui, Ying Qin, Jingjing Wang, Yasir Hayat Khan, Liying Ye, Fuan Xie, Heng Wang, Li Yuan, Jun Y. Slit2 and Robo1 induce opposing effects on metastasis of hepatocellular carcinoma Sk-hep-1 cells. International journal of oncology. vol 49. issue 1. 2017-03-30. PMID:27176045. |
robo1 overexpression upregulated matrix metalloproteinase (mmp)2, -9 and membrane-type1 mmp (mt1-mmp) expression, stimulated mmp2, but not mmp9 activation, and downregulated expression of timp1 and 2. |
2017-03-30 |
2023-08-13 |
human |
| Yun-Qiang Xu, Zhen-Hui Zhang, Yong-Fa Zheng, Shi-Qing Fen. Dysregulated miR-133a Mediates Loss of Type II Collagen by Directly Targeting Matrix Metalloproteinase 9 (MMP9) in Human Intervertebral Disc Degeneration. Spine. vol 41. issue 12. 2017-03-24. PMID:26656045. |
dysregulated mir-133a mediates loss of type ii collagen by directly targeting matrix metalloproteinase 9 (mmp9) in human intervertebral disc degeneration. |
2017-03-24 |
2023-08-13 |
human |
| Xiu-Bo Sang, Kai-Xuan Sun, Li-Li Wang, Shuo Chen, Dan-Dan Wu, Zhi-Hong Zong, Yang Zha. Effects and mechanism of RhoC downregulation in suppressing ovarian cancer stem cell proliferation, drug resistance, invasion and metastasis. Oncology reports. vol 36. issue 6. 2017-03-24. PMID:27748937. |
rt-pcr was used to assess rhoc, cd117, cd133 and matrix metalloproteinase 9 (mmp9) mrna expression levels. |
2017-03-24 |
2023-08-13 |
Not clear |
| H Y Wang, Z Zhang, S Y. Expression of PAPPA2 in human fetomaternal interface and involvement in trophoblast invasion and migration. Genetics and molecular research : GMR. vol 15. issue 3. 2017-03-21. PMID:27525857. |
pappa2-sirna transfection significantly depressed the invasion and migration ability of a trophoblast cell line (htr8/svneo) in a transwell migration and matrigel invasion model compared to a negative control sirna (p < 0.05), also revealing that matrix metalloproteinase 9 (mmp9) secretion is downregulated. |
2017-03-21 |
2023-08-13 |
human |
| Ying Liu, Hui Lv, Xiaoying Wu, Jun Zhou, Ying Shi, Jifang We. Demethylation of Repressor Element-1 Silencing Transcription (REST) Suppresses the Malignant Phenotype of Breast Cancer via MMP9. Oncology research. vol 25. issue 3. 2017-03-21. PMID:27697091. |
furthermore, we also determined matrix metalloproteinase-9 (mmp9) as a target of rest. |
2017-03-21 |
2023-08-13 |
human |
| Xiaoxiao Mao, Zhengxiang Zhou, Ke Xia, Qiong Duan, Yixia Zhao, Dafeng Yang, Yi Xiao, Zhenzhen Liu, Ya Wang, Tianlun Yan. [Y-27632 reduces the MMP2 and MMP9 expression in endothelial cell via inhibition of ROCK signal pathway]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 41. issue 6. 2017-03-20. PMID:27374439. |
to explore the effect of rock inhibitor y-27632 on the matrix metalloproteinase 2 and 9 (mmp2 and mmp9) gene expression and activity in tumor necrosis factor α (tnf-α)-treated human umbilical vein endothelial cell (huvec).
|
2017-03-20 |
2023-08-13 |
human |
| Qian Li, Jing Jin, Jianghui Liu, Liqun Wang, Yutong H. Knockdown of Zinc Transporter ZIP5 by RNA Interference Inhibits Esophageal Cancer Growth In Vivo. Oncology research. vol 24. issue 3. 2017-03-14. PMID:27458102. |
however, we did not find that the downregulation of zip5 caused a change in the relative expressions of cyclin d1, vegf (vascular endothelial growth factor), mmp9 (matrix metalloprotein 9), and bcl-2 (b-cell lymphoma/leukmia-2) mrna or an alteration in the average level of zinc in the peripheral blood and xenografts in vivo. |
2017-03-14 |
2023-08-13 |
Not clear |
| Shengchao Zhang, Jun Yuan, Ruheng Zhen. Suppression of Ubiquitin-Specific Peptidase 17 (USP17) Inhibits Tumorigenesis and Invasion in Non-Small Cell Lung Cancer Cells. Oncology research. vol 24. issue 4. 2017-03-14. PMID:27656837. |
molecular mechanism studies found that usp17 silencing downregulated the expression of matrix metalloproteases (mmp3 and mmp9) in nsclc cells. |
2017-03-14 |
2023-08-13 |
Not clear |
| Yun-Liang Cui, Sheng Zhang, Zhao-Tao Tian, Zhao-Fen Lin, De-Chang Che. Rhubarb Antagonizes Matrix Metalloproteinase-9-induced Vascular Endothelial Permeability. Chinese medical journal. vol 129. issue 14. 2017-03-13. PMID:27411464. |
in this study, we investigated the effects and mechanisms of rhubarb on matrix metalloproteinase-9 (mmp9)-induced vascular endothelial (ve) permeability. |
2017-03-13 |
2023-08-13 |
rat |
| Qian Wang, Wei Yu, Tao Huang, Yan Zhu, Changshan Huan. RUNX2 promotes hepatocellular carcinoma cell migration and invasion by upregulating MMP9 expression. Oncology reports. vol 36. issue 5. 2017-03-10. PMID:27666365. |
notably, runx2 positively regulated matrix metalloproteinase 9 (mmp9) accumulation in hcc cells. |
2017-03-10 |
2023-08-13 |
human |