Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Fong-Sian Lin, Jian-Jr Lee, Alvin Kai-Xing Lee, Chia-Che Ho, Yen-Ting Liu, Ming-You Shi. Calcium Silicate-Activated Gelatin Methacrylate Hydrogel for Accelerating Human Dermal Fibroblast Proliferation and Differentiation. Polymers. vol 13. issue 1. 2021-01-12. PMID:33375390. |
furthermore, si-gelma enhanced cellular adhesion and proliferation, therefore leading to the increased secretion of collagen i other important extracellular matrix (ecm) remodeling-related proteins including ki67, mmp9, and decorin. |
2021-01-12 |
2023-08-13 |
human |
Yi Tan, Carmelo Sgobio, Thomas Arzberger, Felix Machleid, Qilin Tang, Elisabeth Findeis, Jorg Tost, Tasnim Chakroun, Pan Gao, Mathias Höllerhage, Kai Bötzel, Jochen Herms, Günter Höglinger, Thomas Koeglsperge. Loss of fragile X mental retardation protein precedes Lewy pathology in Parkinson's disease. Acta neuropathologica. vol 139. issue 2. 2021-01-12. PMID:31768670. |
reminiscent of fxs neurons, α-syn-overexpressing cells exhibited an increase in membrane n-type calcium channels, increased phosphorylation of erk1/2, eif4e and s6, increased overall protein synthesis, and increased expression of matrix metalloproteinase 9 (mmp9). |
2021-01-12 |
2023-08-13 |
mouse |
Chitra Joseph, Mansour Alsaleem, Nnamdi Orah, Pavan L Narasimha, Islam M Miligy, Sasagu Kurozumi, Ian O Ellis, Nigel P Mongan, Andrew R Green, Emad A Rakh. Elevated MMP9 expression in breast cancer is a predictor of shorter patient survival. Breast cancer research and treatment. vol 182. issue 2. 2021-01-11. PMID:32445177. |
mmp9 is a matricellular protein associated with extracellular matrix (ecm) remodelling, that promotes tumour progression, and modulates the activity of cell adhesion molecules and cytokines. |
2021-01-11 |
2023-08-13 |
Not clear |
Minghui Ou, Chuntang Zhang, Jing Chen, Shibo Zhao, Shichao Cui, Jie T. Overexpression of MicroRNA-340-5p Inhibits Pulmonary Arterial Hypertension Induced by APE by Downregulating IL-1β and IL-6. Molecular therapy. Nucleic acids. vol 21. 2021-01-10. PMID:32712318. |
meanwhile, mir-340-5p led to the blocked nuclear factor κb (nf-κb) pathway with reduced nf-κb p65, matrix metalloproteinase 2 (mmp2), and mmp9 expression in pasmcs. |
2021-01-10 |
2023-08-13 |
human |
Qixin Wang, Isaac K Sundar, Jason L Blum, Jill R Ratner, Joseph H Lucas, Tsai-Der Chuang, Ying Wang, Jie Liu, Virender K Rehan, Judith T Zelikoff, Irfan Rahma. Prenatal Exposure to Electronic-Cigarette Aerosols Leads to Sex-Dependent Pulmonary Extracellular-Matrix Remodeling and Myogenesis in Offspring Mice. American journal of respiratory cell and molecular biology. vol 63. issue 6. 2021-01-07. PMID:32853043. |
mmp9 (matrix metalloproteinase 9), a downstream target of pai-1, was downregulated in both sexes exposed to e-cig aerosols with nicotine. |
2021-01-07 |
2023-08-13 |
mouse |
Minchae Kim, Sora Lee, Chang Seok K. Cellular Behavior of RAW264.7 Cells in 3D Poly(ethylene glycol) Hydrogel Niches. ACS biomaterials science & engineering. vol 5. issue 2. 2021-01-06. PMID:33405849. |
interestingly, we observed the significant upregulation of matrix metalloproteinases (mmps) (i.e., mmp9 and mmp14) as well as m1 polarization markers (i.e., inos, cox2, tnf-α) in 3d, whereas m2 polarization markers (i.e., cd206, arg1, tgf-β) were downregulated. |
2021-01-06 |
2023-08-13 |
Not clear |
Xiaodong Li, Qingshan Huang, Shenglin Wang, Zhen Huang, Fengqiang Yu, Jianhua Li. HER4 promotes the growth and metastasis of osteosarcoma via the PI3K/AKT pathway. Acta biochimica et biophysica Sinica. vol 52. issue 4. 2021-01-06. PMID:32181480. |
her4 overexpression upregulated the expression of phosphorylated protein kinase b (pakt), proliferation marker antigen ki67, and metastasis cell marker matrix metalloproteinase 9 (mmp9). |
2021-01-06 |
2023-08-13 |
mouse |
Zhi Jiao, Lei Huang, Jiali Sun, Jie Xie, Tiantian Wang, Xiu Yin, Haozheng Zhang, Jie Che. Six-transmembrane epithelial antigen of the prostate 1 expression promotes ovarian cancer metastasis by aiding progression of epithelial-to-mesenchymal transition. Histochemistry and cell biology. vol 154. issue 2. 2021-01-01. PMID:32382787. |
matrix metalloproteinase-2 (mmp2) and matrix metalloproteinase-9 (mmp9) activities were examined using matrix metalloproteinase zymography assay. |
2021-01-01 |
2023-08-13 |
human |
Tik-Chee Cheng, Jennifer L Philip, Diana M Tabima, Santosh Kumari, Bakhtiyor Yakubov, Andrea L Frump, Timothy A Hacker, Alessandro Bellofiore, Rongbo Li, Xin Sun, Kara N Goss, Tim Lahm, Naomi C Chesle. Estrogen receptor-α prevents right ventricular diastolic dysfunction and fibrosis in female rats. American journal of physiology. Heart and circulatory physiology. vol 319. issue 6. 2020-12-31. PMID:33064565. |
there was an increased protein expression ratio of timp metallopeptidase inhibitor 1 (timp1) to matrix metalloproteinase 9 (mmp9) in female erαmut compared with wt pab rats, suggesting less collagen degradation. |
2020-12-31 |
2023-08-13 |
rat |
Shyam S Nandi, Kenichi Katsurada, Neeru M Sharma, Daniel R Anderson, Sushil K Mahata, Kaushik P Pate. MMP9 inhibition increases autophagic flux in chronic heart failure. American journal of physiology. Heart and circulatory physiology. vol 319. issue 6. 2020-12-31. PMID:33064567. |
increased matrix metalloprotease 9 (mmp9) after myocardial infarction (mi) exacerbates ischemia-induced chronic heart failure (chf). |
2020-12-31 |
2023-08-13 |
rat |
Katarina Kalavska, Zuzana Cierna, Marian Karaba, Gabriel Minarik, Juraj Benca, Tatiana Sedlackova, Denisa Kolekova, Ivana Mrvova, Daniel Pindak, Jozef Mardiak, Michal Meg. Prognostic role of matrix metalloproteinase 9 in early breast cancer. Oncology letters. vol 21. issue 2. 2020-12-29. PMID:33363615. |
mmp9 is involved in extracellular matrix degradation during various physiological and pathological conditions, including tumorigenesis. |
2020-12-29 |
2023-08-13 |
Not clear |
Jing Jin Gu, Jacob Hoj, Clay Rouse, Ann Marie Pendergas. Mesenchymal stem cells promote metastasis through activation of an ABL-MMP9 signaling axis in lung cancer cells. PloS one. vol 15. issue 10. 2020-12-21. PMID:33119681. |
mscs elicit transcriptional alterations in lung cancer cells leading to increased expression of factors implicated in the epithelial-to-mesenchymal transition (emt) and secreted proteins including matrix metalloproteinase-9 (mmp9). |
2020-12-21 |
2023-08-13 |
Not clear |
Juan Zhao, Xue-Bin Zeng, Hong-Yan Zhang, Jie-Wei Xiang, Yu-Song Li. Long non-coding RNA FOXD2-AS1 promotes cell proliferation, metastasis and EMT in glioma by sponging miR-506-5p. Open medicine (Warsaw, Poland). vol 15. issue 1. 2020-12-19. PMID:33336050. |
in the present study, rt-qpcr was conducted to detect the levels of foxd2-as1 and microrna (mir)-506-5p, and western blot assays were performed to measure the expression of cdk2, cycline1, p21, matrix metalloproteinase (mmp)7, mmp9, n-cadherin, e-cadherin and vimentin in glioma cells. |
2020-12-19 |
2023-08-13 |
human |
Dan Zhang, Dian Li, Lianju Shen, Dong Hu, Bo Tang, Wenhao Guo, Zhang Wang, Zhaoxia Zhang, Guanghui Wei, Dawei H. Exosomes derived from Piwil2‑induced cancer stem cells transform fibroblasts into cancer‑associated fibroblasts. Oncology reports. vol 43. issue 4. 2020-12-16. PMID:32323829. |
protein expression [matrix metalloproteinase (mmp)2, mmp9, α‑smooth muscle actin (α‑sma) and vimentin and fibroblast‑activating protein (fap)] was examined in fbs by western blot analysis. |
2020-12-16 |
2023-08-13 |
Not clear |
Mei Chen, Nan Yang, Judith Lechner, Levente Toth, Ruth Hogg, Giuliana Silvestri, Usha Chakravarthy, Heping X. Plasma level of lipocalin 2 is increased in neovascular age-related macular degeneration patients, particularly those with macular fibrosis. Immunity & ageing : I & A. vol 17. issue 1. 2020-12-12. PMID:33292361. |
this study investigated the plasma levels of lcn2, matrix metalloproteinase 9 (mmp9) and lcn2/mmp9 complex in different types of namd and examined whether the levels were related to patients' responsiveness to anti-vegf therapy. |
2020-12-12 |
2023-08-13 |
Not clear |
Yu Jiang, Yajun Lu, Xu Jiang, Jiawei Hu, Rong Li, Yun Liu, Guoxing Zhu, Xiaoxu Ron. Glucocorticoids induce osteoporosis mediated by glucocorticoid receptor-dependent and -independent pathways. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 125. 2020-12-10. PMID:32044718. |
a dual-luciferase reporter assay further revealed that gcs and nr3c1 transcriptionally regulate matrix metalloproteinase 9 (mmp9), alkaline phosphatase (alp), and acid phosphatase 5a (acp5a). |
2020-12-10 |
2023-08-13 |
zebrafish |
Xue Wen, Yao Xiong, Ling Jin, Ming Zhang, Lei Huang, Yanhong Mao, Chun Zhou, Yuan Qiao, Yuanzhen Zhan. Bisphenol A Exposure Enhances Endometrial Stromal Cell Invasion and Has a Positive Association with Peritoneal Endometriosis. Reproductive sciences (Thousand Oaks, Calif.). vol 27. issue 2. 2020-12-09. PMID:32046440. |
upregulated matrix metalloproteinase (mmp) 2 and mmp9 are involved in the development of ems. |
2020-12-09 |
2023-08-13 |
human |
Peng Wang, Chun Wang, Chunying Li. Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration. Oncology letters. vol 21. issue 1. 2020-12-08. PMID:33281970. |
additionally, dioscin markedly downregulated the expression levels of matrix metalloproteinase 2 (mmp2), mmp9, rho and cdc42, which are all associated with tumor invasion. |
2020-12-08 |
2023-08-13 |
human |
Adriel Barrios-Anderson, Xiaodi Chen, Sakura Nakada, Ray Chen, Yow-Pin Lim, Barbara S Stonestree. Inter-alpha Inhibitor Proteins Modulate Neuroinflammatory Biomarkers After Hypoxia-Ischemia in Neonatal Rats. Journal of neuropathology and experimental neurology. 2020-12-08. PMID:31274164. |
the effects of hiaips on hi-induced neuroinflammation were quantified by image analysis of positively stained astrocytic (glial fibrillary acid protein [gfap]), microglial (ionized calcium binding adaptor molecule-1 [iba-1]), neutrophilic (myeloperoxidase [mpo]), matrix metalloproteinase-9 (mmp9), and mmp9-mpo cellular markers in brain regions. |
2020-12-08 |
2023-08-13 |
human |
Zareen Amtul, Jasmine Randhawa, Abdullah N Najdat, David J Hill, Edith J Aran. Role of Delayed Neuroglial Activation in Impaired Cerebral Blood Flow Restoration Following Comorbid Injury. Cellular and molecular neurobiology. vol 40. issue 3. 2020-12-07. PMID:31522299. |
astrocytes were also found to be releasing matrix metalloproteinase9 (mmp9), which stabilized matrix ligand β-dystroglycan (β-dg) in repaired or functional vessels. |
2020-12-07 |
2023-08-13 |
rat |