| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ailing Sui, Xiuping Chen, Jikui Shen, Anna M Demetriades, Yiyun Yao, Yixuan Yao, Yanji Zhu, Xi Shen, Bing Xi. Inhibiting the NLRP3 inflammasome with MCC950 ameliorates retinal neovascularization and leakage by reversing the IL-1β/IL-18 activation pattern in an oxygen-induced ischemic retinopathy mouse model. Cell death & disease. vol 11. issue 10. 2021-04-09. PMID:33093455. |
moreover, mcc950 could regulate the expression of endothelial cell- and pericyte function-associated molecules, such as vascular endothelial growth factor (vegf), vegf receptor (vegfr)1, vegfr2, matrix metalloproteinase (mmp)2, mmp9, tissue inhibitor of metalloproteinases (timp)1, timp2, platelet-derived growth factor receptor-β (pdgfr-β), platelet-derived growth factor-b (pdgf-b), and angiopoietin2 (ang2). |
2021-04-09 |
2023-08-13 |
mouse |
| Yuanyuan Liu, Yingying Tian, Weizhen Cai, Yao Guo, Changhu Xue, Jingfeng Wan. DHA/EPA-Enriched Phosphatidylcholine Suppresses Tumor Growth and Metastasis via Activating Peroxisome Proliferator-Activated Receptor γ in Lewis Lung Cancer Mice. Journal of agricultural and food chemistry. vol 69. issue 2. 2021-04-06. PMID:33406839. |
in addition, dha-pc and epa-pc significantly decreased the levels of nf-κb-mediated matrix metallopeptidase 9 (mmp9) and heparanase (hpa), which block the extracellular matrix (ecm) degradation, thereby suppressing lung metastasis. |
2021-04-06 |
2023-08-13 |
mouse |
| Yan Chen, Jian Cao, Weixia Peng, Wen Che. Neurotrophin-3 accelerates reendothelialization through inducing EPC mobilization and homing. Open life sciences. vol 15. issue 1. 2021-04-06. PMID:33817212. |
besides, nt-3 promoted the expression of stromal cell-derived factor-1α (sdf-1α), matrix metalloproteinase-9 (mmp9), and chemokine (c-x-c motif) receptor 4 (cxcr4) in epcs, which increased by 59.89%, 74.46%, and 107.7%, respectively, compared with the control group. |
2021-04-06 |
2023-08-13 |
Not clear |
| Xiaolian Fang, Jun Chen, Wei Wang, Guoshuang Feng, Xiaodan Li, Xin Zhang, Yamei Zhang, Jie Zhang, Zhifei Xu, Jun Tai, Xin N. Matrix metalloproteinase 9 (MMP9) level and MMP9 -1562C>T in patients with obstructive sleep apnea: a systematic review and meta-analysis of case-control studies. Sleep medicine. vol 67. 2021-04-05. PMID:31918116. |
matrix metalloproteinase 9 (mmp9) level and mmp9 -1562c>t in patients with obstructive sleep apnea: a systematic review and meta-analysis of case-control studies. |
2021-04-05 |
2023-08-13 |
Not clear |
| Xiaolian Fang, Jun Chen, Wei Wang, Guoshuang Feng, Xiaodan Li, Xin Zhang, Yamei Zhang, Jie Zhang, Zhifei Xu, Jun Tai, Xin N. Matrix metalloproteinase 9 (MMP9) level and MMP9 -1562C>T in patients with obstructive sleep apnea: a systematic review and meta-analysis of case-control studies. Sleep medicine. vol 67. 2021-04-05. PMID:31918116. |
the peripheral level of matrix metalloproteinase (mmp)-9 and polymorphism of mmp9 -1562c>t in patients with obstructive sleep apnea (osa) remains controversial. |
2021-04-05 |
2023-08-13 |
Not clear |
| Fang Chen, Chunyan Yao, Yue Feng, Ying Yu, Honggang Guo, Jing Yan, Jin Che. The identification of neutrophils-mediated mechanisms and potential therapeutic targets for the management of sepsis-induced acute immunosuppression using bioinformatics. Medicine. vol 100. issue 12. 2021-04-02. PMID:33761636. |
the drugs targeting the hub genes and the therapy strategies for sepsis or immunosuppression were reviewed and used to construct the drug-gene-therapy-cell network to illustrate the potential therapeutic roles of the hub genes.a total of 357 overlapping degs between the two groups were identified and were used for the stem clustering analysis, which generated four significant profiles with 195 upregulated (including annexin a1, anxa1; matrix metallopeptidase 9, mmp9; and interleukin 15, il-15) and 151 downregulated degs (including, akt1, ifn-related genes, and hla antigen genes). |
2021-04-02 |
2023-08-13 |
Not clear |
| Xiaoying Qiao, Shreyas Bhave, Lija Swain, Elric Zweck, Lara Reyelt, Paige Crowley, Shiva K Annamalai, Aditya Chennjorwala, Michele Esposito, Allen Razavi, Sina Foroutanjazi, Cody Machen, Katherine Thayer, Lena Jorde, Richard H Karas, Navin K Kapu. Myocardial Injury Promotes Matrix Metalloproteinase-9 Activity in the Renal Cortex in Preclinical Models of Acute Myocardial Infarction. Journal of cardiovascular translational research. 2021-03-30. PMID:33782857. |
we hypothesized that ami promotes inflammation and matrix metalloproteinase-9 (mmp9) activity in the kidney and studied the effect of initiating an impella cp or veno-arterial extracorporeal membrane oxygenation (va-ecmo) before coronary reperfusion during ami. |
2021-03-30 |
2023-08-13 |
Not clear |
| Guobing Chen, Dandan Ge, Bizhen Zhu, Huixuan Shi, Qilin M. Upregulation of matrix metalloproteinase 9 (MMP9)/tissue inhibitor of metalloproteinase 1 (TIMP1) and MMP2/TIMP2 ratios may be involved in lipopolysaccharide-induced acute lung injury. The Journal of international medical research. vol 48. issue 4. 2021-03-22. PMID:32339071. |
upregulation of matrix metalloproteinase 9 (mmp9)/tissue inhibitor of metalloproteinase 1 (timp1) and mmp2/timp2 ratios may be involved in lipopolysaccharide-induced acute lung injury. |
2021-03-22 |
2023-08-13 |
Not clear |
| Jae-Jun Song, Yoon Young Go, Jong Kyou Lee, Bum Sang Lee, Su-Kyoung Park, Harry Jung, Jun Ho Lee, Jiwon Chan. Transcriptomic analysis of tobacco-flavored E-cigarette and menthol-flavored E-cigarette exposure in the human middle ear. Scientific reports. vol 10. issue 1. 2021-03-22. PMID:33247188. |
under menthol-flavored e-liquid treatment, mmp9 (matrix metallopeptidase 9), ptgs2 (prostaglandin-endoperoxide synthase 2), myc (myc proto-oncogene, bhlh transcription factor), hmox1 (heme oxygenase 1), nos3 (nitric oxide synthase 3), and cav1 (caveolin 1) were predicted as key genes. |
2021-03-22 |
2023-08-13 |
human |
| Jun Liu, Xin Song, Zhongwei Re. The effect of microRNA-330 replacement on inhibition of growth and migration in renal cancer cells. Biotechnology and applied biochemistry. 2021-03-22. PMID:33605482. |
quantitative real-time pcr was conducted to assess expression levels of matrix metalloproteinase 2 (mmp2), mmp9, a disintegrin and metalloproteinase with thrombospondin motifs (adamts), kirsten rat sarcoma virus (k-ras), cellular myc (c-myc), and c-x-c chemokine receptor type 4 (cxcr-4) as metastatic genes in the progression of rcc. |
2021-03-22 |
2023-08-13 |
rat |
| Xu-E Chen, Pu Chen, Shanshan Chen, Jin Lu, Ting Ma, Guang Shi, Liang Shen. Long non-coding RNA FENDRR inhibits migration and invasion of cutaneous malignant melanoma cells. Bioscience reports. vol 40. issue 3. 2021-03-19. PMID:32134466. |
the protein expression levels of matrix metallopeptidase 2 (mmp2), mmp9, and related factors in jnk/c-jun pathway were detected using western blot. |
2021-03-19 |
2023-08-13 |
Not clear |
| Yihang Yuan, Jue Wang, Ming Xu, Yunpeng Zhang, Zhiqiang Wang, Leilei Liang, Peng Su. 20(S)-ginsenoside Rh2 as agent for the treatment of LMN-CRC via regulating epithelial-mesenchymal transition. Bioscience reports. vol 40. issue 3. 2021-03-19. PMID:32141497. |
furthermore, the results of western blotting revealed that sgrh2 decreased the expression of matrix metalloproteinase (mmp)-2 and mmp9. |
2021-03-19 |
2023-08-13 |
Not clear |
| Yujing Fan, Kuanyu Wan. miR‑205 suppresses cell migration, invasion and EMT of colon cancer by targeting mouse double minute 4. Molecular medicine reports. vol 22. issue 2. 2021-03-16. PMID:32467998. |
emt processes were suppressed in mir‑205‑overexpressed cells; upregulation of e‑cadherin, and downregulation of n‑cadherin, vimentin, matrix metalloproteinase (mmp)2 and mmp9 were observed. |
2021-03-16 |
2023-08-13 |
mouse |
| William R Swindell, Krzysztof Bojanowski, Ratan K Chaudhur. A novel fumarate, isosorbide di-(methyl fumarate) (IDMF), replicates astrocyte transcriptome responses to dimethyl fumarate (DMF) but specifically down-regulates genes linked to a reactive phenotype. Biochemical and biophysical research communications. vol 532. issue 3. 2021-03-16. PMID:32892947. |
the shared dmf/idmf transcriptome response involved altered expression of antioxidant genes (e.g., hmox1) and genes linked to extracellular matrix integrity (timp3, mmp9) and migration of pro-inflammatory cells into cns (ccl2). |
2021-03-16 |
2023-08-13 |
Not clear |
| Guohong Shi, Zhen Zhan. Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway. Oncology letters. vol 21. issue 4. 2021-03-12. PMID:33692846. |
enzyme-linked immunosorbent assay (elisa) and western blot analysis were utilized to detect the protein levels of matrix metalloproteinase (mmp)2 and mmp9. |
2021-03-12 |
2023-08-13 |
human |
| Datong Sun, Shenghui Yang, Xufeng Zhang, Sai Li, Lin Wang, Junmin Chen, Chun Qiu, Ke X. Forkhead box protein O3a promotes glioma cell resistance to temozolomide by regulating matrix metallopeptidase and β-catenin. Oncology letters. vol 21. issue 4. 2021-03-12. PMID:33692860. |
subsequent experiments demonstrated that, in u87-tr and u251-tr cells, foxo3a knockdown significantly reduced the protein levels of matrix metallopeptidase (mmp)9, while overexpression of foxo3a in u87 and u251 cells enhanced the nuclear accumulation of β-catenin, concomitantly with an increase in mmp9 levels. |
2021-03-12 |
2023-08-13 |
Not clear |
| Yuan Chen, Chengkun Qin, Xianping Cui, Wenmao Geng, Guozhe Xian, Zhiyi Wan. miR-4510 acts as a tumor suppressor in gastrointestinal stromal tumor by targeting APOC2. Journal of cellular physiology. vol 235. issue 7-8. 2021-03-10. PMID:31975384. |
overexpression of mir-4510 also inhibited the phosphorylation of akt and erk1/2, reduced the expression of matrix metallopeptidase 2 (mmp2) and mmp9. |
2021-03-10 |
2023-08-13 |
Not clear |
| Fuzhou Li, Lan Dai, Jixiang Ni. GPX2 silencing relieves epithelial-mesenchymal transition, invasion, and metastasis in pancreatic cancer by downregulating Wnt pathway. Journal of cellular physiology. vol 235. issue 11. 2021-03-08. PMID:31774184. |
gpx2 level in pc tissues, the levels of gpx2, β-catenin, vimentin, snail, epithelial-cadherin (e-cadherin), matrix metalloproteinase 2 (mmp2), mmp9, and wnt2 in cells were determined. |
2021-03-08 |
2023-08-13 |
Not clear |
| Che Wang, Qingmin Li, Honghui Yang, Chuanyu Gao, Qiubo Du, Caili Zhang, Lijie Zhu, Qingman L. MMP9, CXCR1, TLR6, and MPO participant in the progression of coronary artery disease. Journal of cellular physiology. vol 235. issue 11. 2021-03-08. PMID:32052443. |
the degrees of ppi network nodes matrix metallopeptidase 9 (mmp9), c-x-c motif chemokine receptor 1 (cxcr1), toll-like receptor 6 (tlr6), and myeloperoxidase (mpo) were relatively higher. |
2021-03-08 |
2023-08-13 |
human |
| Tung-Wei Hung, Chao-Yang Chu, Chen-Lin Yu, Chu-Che Lee, Li-Sung Hsu, Yong-Syuan Chen, Yi-Hsien Hsieh, Jen-Pi Tsa. Endothelial Cell-Specific Molecule 1 Promotes Endothelial to Mesenchymal Transition in Renal Fibrosis. Toxins. vol 12. issue 8. 2021-03-08. PMID:32781625. |
in esm1-overexpressing mes 13 cells, we also observed elevated expression of mesenchymal markers (n-cadherin, vimentin, matrix metallopeptidase 9 (mmp9)) and the fibrosis marker α-smooth muscle actin (α-sma) and decreased expression of the endothelial marker vascular endothelial cadherin (ve-cadherin) and cd31. |
2021-03-08 |
2023-08-13 |
mouse |