| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E George, G Selama. Haemaglobin Bart's in cord blood of Malaysians. The Southeast Asian journal of tropical medicine and public health. vol 12. issue 1. 1981-09-25. PMID:6894805. |
hb bart's itself is not a simple inherited character but arises from genetically determined imbalance in the biosynthesis of alpha and non alpha chains. |
1981-09-25 |
2023-08-12 |
Not clear |
| E George, G Selama. Haemaglobin Bart's in cord blood of Malaysians. The Southeast Asian journal of tropical medicine and public health. vol 12. issue 1. 1981-09-25. PMID:6894805. |
the rare occurrence of these syndromes in the malays and indians in spite of the presence of hb bart's indicates an altered expression of the alpha thalassaemia gene in these populations. |
1981-09-25 |
2023-08-12 |
Not clear |
| M L North, J Thillet, J Ros. Effect of some physical features and of amino acid substitutions on the mechanical precipitation of hemoglobin. Hemoglobin. vol 5. issue 4. 1981-09-15. PMID:7251379. |
we have studied the mechanical stability of hb crétil (beta 89 ser leads to asn), hb hope (beta 136 gly leads to asp), hb strasbourg (beta 23 val leads to asp), and the hybrid hb s/stanleyville-ii (beta 6 glu leads to val: alpha 78 asn leads to lys) by the method of roth et al. |
1981-09-15 |
2023-08-12 |
Not clear |
| M L North, J Thillet, J Ros. Effect of some physical features and of amino acid substitutions on the mechanical precipitation of hemoglobin. Hemoglobin. vol 5. issue 4. 1981-09-15. PMID:7251379. |
from comparisons with published results, but excluding thermosensitive hbs, we conclude that: - standard methods for isolation of hemoglobins modify its mechanical stability, - alpha mutation increases the mechanical stability of hb s in the hybrid hb s/st-ii, - some mutations produce a more stable hemoglobin than hb a. |
1981-09-15 |
2023-08-12 |
Not clear |
| R Vestri, S Salmaso, S G Condò, E Antonin. Distribution and respiratory properties of sheep hemoglobins A and B containing the II alphaHis chain. Hemoglobin. vol 5. issue 4. 1981-09-15. PMID:7251380. |
oxygen equilibrium determination showed no differences in the oxygen affinity, the bohr effect and the heme-heme interaction of hb a (alpha 2 beta 2a) and hb b (alpha 2 beta 2b), each containing one of the three possible alpha chain phenotypes. |
1981-09-15 |
2023-08-12 |
Not clear |
| M Goodma. Globin evolution was apparently very rapid in early vertebrates: a reasonable case against the rate-constancy hypothesis. Journal of molecular evolution. vol 17. issue 2. 1981-09-15. PMID:7253036. |
it was found that the three types of gnathostome globins (mb, alpha hb, beta hb) evolved between the shark-boney vertebrate and bird-mammal ancestors at a much faster rate than from the latter ancestor to the present. |
1981-09-15 |
2023-08-12 |
mouse |
| A E Felice, C A Altay, P F Milner, T H Huisma. The occurrence and identification of alpha-thalassemia-2 among hemoglobin S heterozygotes. American journal of clinical pathology. vol 76. issue 1. 1981-09-15. PMID:7258153. |
the percentages of hb s (which fell between 27% and 42%) and the mean corpuscular volume values correlated directly with the alpha/non-alpha values, confirming previous suggestions (huisman, hemoglobin 1:349, 1977) that the concomitant occurrence of an alpha-thalassemia-2 heterozygosity (alpha alpha(0)/alpha alpha; beta/beta(s)) or homozygosity (alpha(0) alpha/alpha(0) alpha; beta/beta(s)) resulted in intermediate or lower levels of hb s compared with hb s heterozygotes having four active alpha-chain genes (alpha alpha/alpha alpha; beta/beta(s)). |
1981-09-15 |
2023-08-12 |
Not clear |
| H Furuta, M Ohe, A Kajit. Ligand-dependent polymerization of tetrameric hemoglobin from the blood clam Anadara broughtonii. Biochimica et biophysica acta. vol 668. issue 3. 1981-08-20. PMID:7236720. |
hemoglobin (hb ii) of the blood clam anadara broughtonii has a alpha 2 beta 2 sub-unit structure in athe oxy form with a sedimentation constant of 4.8 s. when deoxygenated, hb ii polymerizes with a major component, s20,w = 11.5 (above 150 microm in heme). |
1981-08-20 |
2023-08-12 |
Not clear |
| T H Huisman, A L Reese, B Webber, K Okonjo, C Altay, A E Felic. In vitro synthesis of hemoglobin and hemoglobin chains in the BFUe-derived colonies form person with alpha- or beta-thalassemia. American journal of hematology. vol 10. issue 3. 1981-08-10. PMID:6166190. |
the synthesis of alpha and non-alpha chains of human hemoglobin (hb) was studied in reticulocytes and in bfue-derived cell colonies from patients with alpha chain or beta chain deficiencies. |
1981-08-10 |
2023-08-12 |
human |
| T H Huisman, A L Reese, B Webber, K Okonjo, C Altay, A E Felic. In vitro synthesis of hemoglobin and hemoglobin chains in the BFUe-derived colonies form person with alpha- or beta-thalassemia. American journal of hematology. vol 10. issue 3. 1981-08-10. PMID:6166190. |
the subjects included normal adults (alpha alpha/alpha alpha) with or without a beta chain variant (hb s, hb leslie) or an alpha chain variant (hb g-georgia); alpha-thalassemia-2 heterozygotes (alpha 0 alpha/alpha alpha) with an alpha chain variant (g-georgia or g-philadelphia); an alpha-thalassemia-1 heterozygote (alpha 0 alpha 0/alpha alpha); alpha-thalassemia-2 homozygotes (alpha 0 alpha 0/alpha 0 alpha) with a beta chain variant (hb s), an alpha chain variant (g-philadelphia), a hb s homozygosity with hb g-philadelphia, or a hb g-philadelphia homozygosity; and three black beta +-thalassemia homozygotes. |
1981-08-10 |
2023-08-12 |
human |
| P E Nute, T Papayannopoulou, B Tatsis, G Stamatoyannopoulo. Toward a system for detecting somatic-cell mutations. V. Preparation of fluorescent antibodies to hemoglobin hasharon, a human alpha-chain variant. Journal of immunological methods. vol 42. issue 1. 1981-08-10. PMID:6787135. |
antibodies against the abnormal human hemoglobin, hb hasharon (alpha 47 asp leads to his), were raised in horse and purified by absorption against sepharose 4b to which normal hemoglobins or hb hasharon were bound. |
1981-08-10 |
2023-08-12 |
human |
| A B Kriegler, T R Bradley, G S Hodgson, I K McNiec. Identification of the "factor" in erythrocyte lysates which enhances colony growth in agar cultures. Experimental hematology. vol 9. issue 1. 1981-08-10. PMID:6972314. |
since the enhancement activity is associated with both the alpha and beta globin peaks even under these dissociating conditions, it has been concluded that the enhancement factor in erythrocyte lysates is hb itself. |
1981-08-10 |
2023-08-12 |
mouse |
| V A Spivak, T P Molchanova, N V Ermakov, Tokarev YuN, G Martinez, J Szelenyi, M Horanyi, J Foldi, S Hollan, H Kazieva, I A Shamo. A new hemoglobin variant: Hb Dagestan alpha 60(E9) Lys leads to Glu. Hemoglobin. vol 5. issue 2. 1981-06-23. PMID:6783600. |
a new hemoglobin variant: hb dagestan alpha 60(e9) lys leads to glu. |
1981-06-23 |
2023-08-12 |
Not clear |
| T Asakura, K Adachi, E Schwartz, J Wile. Molecular stability of Hb Philly (alpha 2 beta 2 35(Cl) Tyr leads to Phe). Rhe relationship of hemoglobin stability to ligand state as defined by heat and mechanical shaking tests. Hemoglobin. vol 5. issue 2. 1981-06-23. PMID:7216817. |
molecular stability of hb philly (alpha 2 beta 2 35(cl) tyr leads to phe). |
1981-06-23 |
2023-08-12 |
Not clear |
| T Asakura, K Adachi, E Schwartz, J Wile. Molecular stability of Hb Philly (alpha 2 beta 2 35(Cl) Tyr leads to Phe). Rhe relationship of hemoglobin stability to ligand state as defined by heat and mechanical shaking tests. Hemoglobin. vol 5. issue 2. 1981-06-23. PMID:7216817. |
the molecular stability of hb philly (alpha 2 beta 2 35(cl) tyr leads to phe) with different ligand states was compared with that of hb a and hb s using mechanical shaking and heat stability tests. |
1981-06-23 |
2023-08-12 |
Not clear |
| A Maggio, A Massa, A Giampaolo, F Mavilio, L Tentor. Occurrence of Hb M Iwate (alpha 2 87 His leads to Tyr beta 2) in an Italian carrier. Hemoglobin. vol 5. issue 2. 1981-06-23. PMID:7216821. |
occurrence of hb m iwate (alpha 2 87 his leads to tyr beta 2) in an italian carrier. |
1981-06-23 |
2023-08-12 |
Not clear |
| J A Jones, H K Broszeit, C N LeCrone, J C Dette. An improved method for detection of red cell hemoglobin H inclusions. The American journal of medical technology. vol 47. issue 2. 1981-06-13. PMID:6261580. |
this simple test is useful in the diagnosis of alpha thalassemia trait; however, the search for hb h containing cells in often very tedious. |
1981-06-13 |
2023-08-12 |
Not clear |
| G R Honig, L N Vida, M Shamsuddin, R G Mason, H W Schlumpf, R A Luk. Hemoglobin Milledgeville (alpha 44 (CD2) Pro leads to Leu): a new variant with increased oxygen affinity. Biochimica et biophysica acta. vol 626. issue 2. 1981-06-13. PMID:7213661. |
the hb a2 fraction as well as hb a from erythrocytes of affected individuals exhibited increased oxygen affinity, indicating that the altered oxygen equilibrium was the result of a hemoglobin alpha chain abnormality. |
1981-06-13 |
2023-08-12 |
Not clear |
| H R Marti, R Scherrer, M Pille. [Clinicohematologic effects of hemoglobin Altdorf (alpha 2 beta 2 135 Ala replaced by Pro)]. Folia haematologica (Leipzig, Germany : 1928). vol 107. issue 4. 1981-05-26. PMID:6162732. |
hb altdorf alpha 2 beta 2 135 ala leads to pro is an unstable variant occurring near lecce in italy. |
1981-05-26 |
2023-08-12 |
Not clear |
| M L North, W Hassan, J Thillet, M Schwartz, C Taubert, J Ritter, R Gandar, J Ros. [Clinical and biological studies of an hybrid S/Stanleyville II hemoglobin (alpha 2 78 Asn replaced by Lys beta 2 6 Glu replaced by Val) (author's transl)]. Nouvelle revue francaise d'hematologie. vol 22. issue 3. 1981-05-13. PMID:6782549. |
a report of a doubly heterozygous case for both haemoglobins: hb stanleyville ii (alpha 78 replaced by lys) and hb s (beta 6 glu replaced by val) with hb hybrid s/st ii. |
1981-05-13 |
2023-08-12 |
Not clear |