| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Goodma. Globin evolution was apparently very rapid in early vertebrates: a reasonable case against the rate-constancy hypothesis. Journal of molecular evolution. vol 17. issue 2. 1981-09-15. PMID:7253036. |
it was found that the three types of gnathostome globins (mb, alpha hb, beta hb) evolved between the shark-boney vertebrate and bird-mammal ancestors at a much faster rate than from the latter ancestor to the present. |
1981-09-15 |
2023-08-12 |
mouse |
| A E Felice, C A Altay, P F Milner, T H Huisma. The occurrence and identification of alpha-thalassemia-2 among hemoglobin S heterozygotes. American journal of clinical pathology. vol 76. issue 1. 1981-09-15. PMID:7258153. |
the percentages of hb s (which fell between 27% and 42%) and the mean corpuscular volume values correlated directly with the alpha/non-alpha values, confirming previous suggestions (huisman, hemoglobin 1:349, 1977) that the concomitant occurrence of an alpha-thalassemia-2 heterozygosity (alpha alpha(0)/alpha alpha; beta/beta(s)) or homozygosity (alpha(0) alpha/alpha(0) alpha; beta/beta(s)) resulted in intermediate or lower levels of hb s compared with hb s heterozygotes having four active alpha-chain genes (alpha alpha/alpha alpha; beta/beta(s)). |
1981-09-15 |
2023-08-12 |
Not clear |
| H Furuta, M Ohe, A Kajit. Ligand-dependent polymerization of tetrameric hemoglobin from the blood clam Anadara broughtonii. Biochimica et biophysica acta. vol 668. issue 3. 1981-08-20. PMID:7236720. |
hemoglobin (hb ii) of the blood clam anadara broughtonii has a alpha 2 beta 2 sub-unit structure in athe oxy form with a sedimentation constant of 4.8 s. when deoxygenated, hb ii polymerizes with a major component, s20,w = 11.5 (above 150 microm in heme). |
1981-08-20 |
2023-08-12 |
Not clear |
| T H Huisman, A L Reese, B Webber, K Okonjo, C Altay, A E Felic. In vitro synthesis of hemoglobin and hemoglobin chains in the BFUe-derived colonies form person with alpha- or beta-thalassemia. American journal of hematology. vol 10. issue 3. 1981-08-10. PMID:6166190. |
the synthesis of alpha and non-alpha chains of human hemoglobin (hb) was studied in reticulocytes and in bfue-derived cell colonies from patients with alpha chain or beta chain deficiencies. |
1981-08-10 |
2023-08-12 |
human |
| T H Huisman, A L Reese, B Webber, K Okonjo, C Altay, A E Felic. In vitro synthesis of hemoglobin and hemoglobin chains in the BFUe-derived colonies form person with alpha- or beta-thalassemia. American journal of hematology. vol 10. issue 3. 1981-08-10. PMID:6166190. |
the subjects included normal adults (alpha alpha/alpha alpha) with or without a beta chain variant (hb s, hb leslie) or an alpha chain variant (hb g-georgia); alpha-thalassemia-2 heterozygotes (alpha 0 alpha/alpha alpha) with an alpha chain variant (g-georgia or g-philadelphia); an alpha-thalassemia-1 heterozygote (alpha 0 alpha 0/alpha alpha); alpha-thalassemia-2 homozygotes (alpha 0 alpha 0/alpha 0 alpha) with a beta chain variant (hb s), an alpha chain variant (g-philadelphia), a hb s homozygosity with hb g-philadelphia, or a hb g-philadelphia homozygosity; and three black beta +-thalassemia homozygotes. |
1981-08-10 |
2023-08-12 |
human |
| P E Nute, T Papayannopoulou, B Tatsis, G Stamatoyannopoulo. Toward a system for detecting somatic-cell mutations. V. Preparation of fluorescent antibodies to hemoglobin hasharon, a human alpha-chain variant. Journal of immunological methods. vol 42. issue 1. 1981-08-10. PMID:6787135. |
antibodies against the abnormal human hemoglobin, hb hasharon (alpha 47 asp leads to his), were raised in horse and purified by absorption against sepharose 4b to which normal hemoglobins or hb hasharon were bound. |
1981-08-10 |
2023-08-12 |
human |
| A B Kriegler, T R Bradley, G S Hodgson, I K McNiec. Identification of the "factor" in erythrocyte lysates which enhances colony growth in agar cultures. Experimental hematology. vol 9. issue 1. 1981-08-10. PMID:6972314. |
since the enhancement activity is associated with both the alpha and beta globin peaks even under these dissociating conditions, it has been concluded that the enhancement factor in erythrocyte lysates is hb itself. |
1981-08-10 |
2023-08-12 |
mouse |
| V A Spivak, T P Molchanova, N V Ermakov, Tokarev YuN, G Martinez, J Szelenyi, M Horanyi, J Foldi, S Hollan, H Kazieva, I A Shamo. A new hemoglobin variant: Hb Dagestan alpha 60(E9) Lys leads to Glu. Hemoglobin. vol 5. issue 2. 1981-06-23. PMID:6783600. |
a new hemoglobin variant: hb dagestan alpha 60(e9) lys leads to glu. |
1981-06-23 |
2023-08-12 |
Not clear |
| T Asakura, K Adachi, E Schwartz, J Wile. Molecular stability of Hb Philly (alpha 2 beta 2 35(Cl) Tyr leads to Phe). Rhe relationship of hemoglobin stability to ligand state as defined by heat and mechanical shaking tests. Hemoglobin. vol 5. issue 2. 1981-06-23. PMID:7216817. |
molecular stability of hb philly (alpha 2 beta 2 35(cl) tyr leads to phe). |
1981-06-23 |
2023-08-12 |
Not clear |
| T Asakura, K Adachi, E Schwartz, J Wile. Molecular stability of Hb Philly (alpha 2 beta 2 35(Cl) Tyr leads to Phe). Rhe relationship of hemoglobin stability to ligand state as defined by heat and mechanical shaking tests. Hemoglobin. vol 5. issue 2. 1981-06-23. PMID:7216817. |
the molecular stability of hb philly (alpha 2 beta 2 35(cl) tyr leads to phe) with different ligand states was compared with that of hb a and hb s using mechanical shaking and heat stability tests. |
1981-06-23 |
2023-08-12 |
Not clear |
| A Maggio, A Massa, A Giampaolo, F Mavilio, L Tentor. Occurrence of Hb M Iwate (alpha 2 87 His leads to Tyr beta 2) in an Italian carrier. Hemoglobin. vol 5. issue 2. 1981-06-23. PMID:7216821. |
occurrence of hb m iwate (alpha 2 87 his leads to tyr beta 2) in an italian carrier. |
1981-06-23 |
2023-08-12 |
Not clear |
| J A Jones, H K Broszeit, C N LeCrone, J C Dette. An improved method for detection of red cell hemoglobin H inclusions. The American journal of medical technology. vol 47. issue 2. 1981-06-13. PMID:6261580. |
this simple test is useful in the diagnosis of alpha thalassemia trait; however, the search for hb h containing cells in often very tedious. |
1981-06-13 |
2023-08-12 |
Not clear |
| G R Honig, L N Vida, M Shamsuddin, R G Mason, H W Schlumpf, R A Luk. Hemoglobin Milledgeville (alpha 44 (CD2) Pro leads to Leu): a new variant with increased oxygen affinity. Biochimica et biophysica acta. vol 626. issue 2. 1981-06-13. PMID:7213661. |
the hb a2 fraction as well as hb a from erythrocytes of affected individuals exhibited increased oxygen affinity, indicating that the altered oxygen equilibrium was the result of a hemoglobin alpha chain abnormality. |
1981-06-13 |
2023-08-12 |
Not clear |
| H R Marti, R Scherrer, M Pille. [Clinicohematologic effects of hemoglobin Altdorf (alpha 2 beta 2 135 Ala replaced by Pro)]. Folia haematologica (Leipzig, Germany : 1928). vol 107. issue 4. 1981-05-26. PMID:6162732. |
hb altdorf alpha 2 beta 2 135 ala leads to pro is an unstable variant occurring near lecce in italy. |
1981-05-26 |
2023-08-12 |
Not clear |
| M L North, W Hassan, J Thillet, M Schwartz, C Taubert, J Ritter, R Gandar, J Ros. [Clinical and biological studies of an hybrid S/Stanleyville II hemoglobin (alpha 2 78 Asn replaced by Lys beta 2 6 Glu replaced by Val) (author's transl)]. Nouvelle revue francaise d'hematologie. vol 22. issue 3. 1981-05-13. PMID:6782549. |
a report of a doubly heterozygous case for both haemoglobins: hb stanleyville ii (alpha 78 replaced by lys) and hb s (beta 6 glu replaced by val) with hb hybrid s/st ii. |
1981-05-13 |
2023-08-12 |
Not clear |
| A Giuliani, D Maffi, M P Cappabianca, L Tentor. Hemoglobin Legnano (alpha 2 141 (HC3) Arg leads to Leu beta2) a new high oxygen affinity variant. Functional and structural studies. Journal of biochemistry. vol 88. issue 5. 1981-04-21. PMID:7462179. |
hb legnano (alpha 2 141 (hc3) arg leads to leu beta 2) is an abnormal hemoglobin, for which preliminary structural and functional studies demonstrated an amino acid substitution (arg leads to leu) in the alpha-c-terminus. |
1981-04-21 |
2023-08-12 |
Not clear |
| A Giuliani, D Maffi, M P Cappabianca, L Tentor. Hemoglobin Legnano (alpha 2 141 (HC3) Arg leads to Leu beta2) a new high oxygen affinity variant. Functional and structural studies. Journal of biochemistry. vol 88. issue 5. 1981-04-21. PMID:7462179. |
the findings are compared with those for hb suresnes (alpha 2 141 (hc3) arg leads his beta2) and hb-cpb, a normal hemoglobin in which the c-terminal alpha 141 arg has been cleaved by carboxypeptidase b. hb legnano, like the other hemoglobins considered, shows an increased p50, a decreased hill's "n" values and a decreased bohr effect that are partially restored in presence of organic phosphates. |
1981-04-21 |
2023-08-12 |
Not clear |
| O Castro, W P Winter, T C Lee, V E Heading. Prevalence of alpha-chain variants at birth. American journal of clinical pathology. vol 75. issue 1. 1981-03-27. PMID:7457429. |
although the expected frequency of the genes for hemoglobins s and c were observed, six newborns (five kindreds) were heterozygous for an alpha g hb. |
1981-03-27 |
2023-08-12 |
Not clear |
| O Castro, W P Winter, T C Lee, V E Heading. Prevalence of alpha-chain variants at birth. American journal of clinical pathology. vol 75. issue 1. 1981-03-27. PMID:7457429. |
in four kindreds, the alpha chain variant was identified as hb g-philadelphia. |
1981-03-27 |
2023-08-12 |
Not clear |
| O Castro, W P Winter, T C Lee, V E Heading. Prevalence of alpha-chain variants at birth. American journal of clinical pathology. vol 75. issue 1. 1981-03-27. PMID:7457429. |
in each case, heterozygosity for this hb was manifested at birth by the presence of hb f/g (alpha 2 g gamma 2), a slow hb migrating between the positions of hbs s and c on cellulose acetate. |
1981-03-27 |
2023-08-12 |
Not clear |